A Case of Elderly Woman with Various Preexisting Conditions who Successfully Underwent Fullterm Delivery with the Combined Use of Tokishakuyakusan and Shokenchuto / 日本東洋医学雑誌

The case is a 38-year-old obese woman with complications such as idiopathic thrombocytopenic purpura, thyroid dysfunction, endometriosis, and uterine myoma. She had a wide variety of medical histories and had a long history of infertility treatment, and received various treatments. She has also undergone laparotomy for uterine myoma after the start of infertility treatment. We treated her with Kampo medicine for multiple complaints that appeared during infertility treatment. She received a combination therapy of tokishakuyakusan and shokenchuto, and after about 3 months, her symptoms improved and she became pregnant. In addition, bukuryoin and ryokankyomishingeninto, which were additionally used for hyperemesis gravidarum and cough during pregnancy, were also effective. The course of the pregnancy was uneventful and she gave birth to a girl at term. The girl is growing and developing normally without asphyxia, malformations, etc. It was suggested that it is necessary to pay attention not only to blood stasis and renal deficiency but also to spleen deficiency and consumptive disorder in Kampo medicine treatment for infertility and recurrent miscarriage.

A Case of Pediatric Auditory Processing Disorder Caused by Psychological Stress Successfully Treated with Shokenchuto / 日本東洋医学雑誌

In auditory processing disorder (APD), hearing difficulties occur in noisy or otherwise difficult environments, despite no hearing loss. Most APD patients have developmental disabilities, weak cognitive function, or psychological problems. Here, we report a case of a child who was thought to have developed APD due to mental stress and had a good course using shokenchuto. The case was a 12-year-old girl. She began to be bullied 2 years ago, and from that time she began to find it was difficult to hear the words in a noisy environment. She visited our department and was diagnosed with APD without any abnormalities in various hearing tests. We administered her shokenchuto. After 12 weeks, she felt almost no inconvenience in hearing. She also regained her usual energy and became to be able to shrug off bullying without worrying too much. Afterwards, her symptoms subsided. After 20 weeks, the medication was discontinued.

A Case of Sleep Terrors with Sleepwalking Whose Therapeutic Effect by the Kampo Medicine Shokenchuto was Confirmed by Overnight Polysomnography / 日本東洋医学雑誌

We report a case of sleep terrors complicated with sleepwalking. The patient was 9-year-old boy who suddenly woke up, walked, or screamed in his sleep. These symptoms were sometimes induced by such as fever elevation or school events. In order to prevent injury while sleeping, he was suggested taking medicine to suppress the nocturnal behavior. After taking shokenchuto based on his findings of qi deficiency, the episodes gradually disappeared and the frequency of fever elevation decreased. In this report, we present the improvements of sleep parameters provided by overnight polysomnography, performed before and after treatment. Shokenchuto is known as one of the curative medicines for sleep terrors, but this is the first report showing objective therapeutic effects using overnight polysomnography.

A Case of Secondary Amenorrhea with Polycystic Ovary Syndrome Successfully Treated with Shokenchuto / 日本東洋医学雑誌

Here, we report a case of adolescent woman with secondary amenorrhea complicated with polycystic ovary syndrome, which had a normal menstrual period after prescribed shokenchuto under the therapy based on Kampo diagnosis. The case is 14-year-old woman, who had already hormonal therapy due to the secondary amenorrhea, and was difficult to treat because of edema and weight gain. Secondary amenorrhea, multiple cysts in the ovary, and hypertestosteroneemia were confirmed, and the patient was diagnosed with polycystic ovary syndrome. Abdominal pattern was weak and the abnormalities of the abdominal strength were prominent. Therefore, we administered her shokenchuto. After two weeks, menstruation began, and thereafter the menstruation had progressed without any irregularities. Blood examination also showed normal testosterone level. It was suggested that it would be important to focus on the preparation for digestive function and to treat the secondary amenorrhea of adolescent women.

A Case Report of Pyoderma Chronica Capillitii Successfully Treated with Shokenchuto and Hainosankyuto / 日本東洋医学雑誌

We report a case of pyoderma chronica capillitii successfully treated with shokenchuto. The patient was a 20-­year-­old man, who had been suffering from an abscess and hair loss in the occipital region of his scalp for the past 6 months ; the lesion was gradually enlarging and was 3×3 cm in diameter at presentation. He was di­agnosed with pyoderma chronica capillitii by a dermatologist and treated with puncture and drainage, multiple courses of oral antibiotics, and focal injections of tetracycline twice, with no beneficial response. Furthermore, another similar abscess with hair loss appeared on his occipital scalp and a new similar nodule appeared on his right cheek. He consulted my clinic to receive Kampo therapy. His abdominal examination revealed spasm of the bilateral rectus abdominis ; his abdomen was remarkably hypersensitive. He felt tickling intensely on ab­dominal palpation. Based on these findings, he was treated with shokenchuto, and hainosankyuto was added to relieve his symptoms. After a month of therapy, the nodule on his cheek disappeared, and several months later, the two occipital lesions improved and growth of new hair was noted. With continued treatment, his scalp and hair lesions healed completely and no recurrence was noted. To our knowledge, there is no previous report on the treatment of pyoderma chronica capillitii with shokenchuto. Based on the Kampo diagnostic pattern, Kampo medicine can be a beneficial therapeutic option for pyoderma chronica in cases where standard treatments are ineffective.

<b>A Case of Low Vision with Tonic Accommodation Exacerbated by Fatigue and Successfully Treated by </b><b>Shokenchuto</b> / 日本東洋医学雑誌

<p>An 8-year-old girl was admitted with vision loss. She had no history of amblyopia or other eye diseases. On examination, both eyes showed vision loss and uncorrected myopia, regardless of visual acuity correction by glasses. Her symptoms were considered exacerbated by fatigue. We diagnosed tonic accommodation because a regulatory paralysis agent provided relief. The patient had been treated with tropicamide methyl sulfate and neostigmine, but her visual acuity did not change. Based on a Kampo diagnosis, she was prescribed Shokenchuto. After 4 months' administration, her uncorrected vision improved by 1.2 in both eyes, and her visual acuity was maintained even when fatigued. Kampo medicine can be a treatment option for tonic accommodation in cases where standard treatments are ineffective.</p>

<b>Four Cases of Palpitation with Weak Constitution Successfully Treated with Shokenchuto</b> / 日本東洋医学雑誌

The treatment of palpitation with a weak constitution through the use of modern western medicines is often difficult. We report here 4 cases of palpitation with weak constitution, which were successfully treated with shokenchuto. Case 1 was a 67-year-old female, who complained of palpitation, as well as anorexia and easy fatigability. An electrocardiogram (ECG) showed premature supraventricular contractions. Case 2 was an 83-year-old female, who also complained of palpitation and gastrointestinal dysfunction. ECG revealed premature ventricular contraction. Case 3 was a 34-year-old male, who complained of palpitation with gastrointestinal dysfunction and diarrhea. ECG findings were characteristic of Brugada syndrome. Case 4 was a 71-year-old female, who complained of palpitation and concomitant diarrhea and anorexia. All patients demonstrated tension of bilateral rectus abdominis muscles. After we prescribed shokenchuto, most of their symptoms improved. Thus, shokenchuto may be a suitable herbal medicine for patients with weak constitution presenting with palpitation.

<b>Five Cases of Chronic Primary Headache in Children Successfully Treated with Shokenchuto </b> / 日本東洋医学雑誌

Recently, the authors experienced five cases of chronic primary headache in children which were successfully treated with shokenchuto. This report describes the details of these five cases and results of references in past literature. The common physical findings in these five cases were soft abdominal walls with a spasmodic bilateral m. rectus abdominis. There was only one case report of headache which was successfully treated with shokenchuto. We believe that our case report sheds light on a new aspect of shokenchuto, which might be a useful formulation for chronic headache. In this paper, we also speculate about the mechanism of this formulation for headache from the view point of former research showing the relationship between brain orexin behavior, and ghrelin which is induced from the digestive system.

<b>A Case of Painful Palm and Sole with Burning Sensation Successfully Treated with the Kampo Formulation, Shokenchuto </b> / 日本東洋医学雑誌

A 67 year-old women who suffered from painful palms and soles with burning sensation for 2 years was treated. At first, she visited the department of dermatology and then consulted our department. The authors considered these symptoms as already being described in the great classic <i>Kinkiyoryaku </i>(<i>Chin Keiu Yao Lueh</i>). We then prescribed shokenchuto, which resulted immediate clinical improvement. The authors have again realized that the classical textbook is based on proper clinical observations that are useful today.

Case Report of Infantile Hydrocele Successfully Treated with Therapy Based on Kampo Diagnosis / 日本東洋医学雑誌

We experienced a case of infantile hydrocele with operation indication successfully treated with therapy based on Kampo diagnosis. The case was 4 years-old boy who was advised about an operation with the diagnosis of left hydrocele. At first, goreisan extract was administered, which resulted in a reduction of his hydrocele. However, the condition had worsened after his entrance into preschool. So, we changed the formulation to shokenchuto extract, which resulted in the disappearance of the hydrocele. Up to now, there has been no recurrence. We suggest that it is worthwhile to treat infantile hydrocele patients with Kampo medicine for a certain period of time, if their family gives consent. Moreover, shokenchuto or similar formulations might be practicable for such hydrocele, in addition to formulae which regulate body fluids.

Four Cases Report of Dumping Syndrome Effectively Treated with Keishito and its additional Prescription / 日本東洋医学雑誌

We report four patients suffering from dumping syndrome treated effectively with Keishito and its additional prescription. Case1was a 57-year old male who received subtotal gastrectomy 30 years ago. After the operation he felt shaking sensations and eyes flickering after meals for10minutes to 4 hours. These symptoms tended to occur along with hunger. After taking Keishito, these symptoms improved. Case 2 was a 63-year old male who received subtotal gastrectomy 7 years ago. In recent years, he has had noticeable sweat and fatigability 20-30 minutes after meals. After taking Keishito, these dumping syndrome symptoms disappear. Case 3 was a 71-year old female who received subtotal gastrectomy 9 years ago. Thereafter, cold sweats and dizziness came to appear regardless of what she ate. After taking keishikashakuyakuto or shokenchuto the aforementioned symptoms disappeared. Case 4 was a 72-year old female who received subtotal gastrectomy 2 years ago. Sweats and hot flushes began to occur after meals for 30 minutes to 3 hours, from last July. These symptoms were improved simply by licking candy. After taking Keishito, these symptoms also disappeared.

Kampo for Otorhinolaryngologic Infections in Handicapped Children / 日本東洋医学雑誌

In their infant years, physically handicapped children have a tendency to develop infections, otitis media, tonsillitis and acute sinusitis repeatedly because their physical development is retarded and metabolism poor.<br>A combination of shosaiko-to and Shokenchu-to were prescribed to a 3-year-old boy with Down's syndrome. and a 2-year-old boy with cerebral palsy. They caught fewer colds, stopped contracting infections, and digestive symptoms were ameliorated. When the sho, or Kampo diagnostic procedure, was followed in the administration of the above combination or other Kampo formulas during infection remission, they were effective in improving weak constitutions.<br>When a combination of Shosaiko-to and Keishikashakuyaku-to were prescribed for a mantally handicapped 14-year-old boy who suffered from frequent colds and acute sinusitis, good results were obtained. Although the patient's physical development was normal, he became weak due to his poor basic physical habits, such as snacking, which arose from his retarded mental development.