Effect of Modified Cangfu Daotantang on Glucose and Lipid Metabolism in Simple Obese Children with Phlegm Dampness and Stagnation / 中国实验方剂学杂志

ObjectiveTo observe and compare the intervention effect of modified Cangfu Daotantang on glucose and lipid metabolism in simple obese children with phlegm dampness and stagnation. MethodA total of 60 children with simple obesity were randomly divided into two groups according to the simple randomization method of the random number table. The odd number was included in the test group， and the even number was included in the basic treatment group， with 30 cases in each group. On the basis of signing the informed consent notice， the treatment group was given modified Cangfu Daotantang combined with basic treatment， while the control group was only given basic treatment. After three months of treatment， the body mass index （BMI）， glucose and lipid metabolism level ［total cholesterol （TC）， triglyceride （TG）， low-density lipoprotein cholesterol （LDL-C）， fasting plasma glucose （FPG）， fasting insulin （FINS）， and homeostasis model assessment-insulin resistance （HOMA-IR）］， the change in the total score of traditional Chinese medicine （TCM） syndromes， and the effective rate of treatment were observed and compared. ResultAfter treatment， the BMI of the observation group and the control group decreased significantly （P<0.01）. Compared with the control group， the BMI level in the observation group decreased significantly （P<0.05）. After treatment， the levels of TC， TG， and LDL-C in the observation group and the control group decreased significantly （P<0.01）. Compared with the control group， the levels of TC， TG， and LDL-C in the observation group decreased significantly （P<0.05）. In addition， the level of TC in the observation group improved significantly compared with that in the control group （P<0.01）. The levels of FPG， FINS， and HOMA-IR in the observation group and the control group were significantly lower than those before treatment （P<0.05）. After treatment， compared with the control group， the levels of FPG， FINS， and HOMA-IR in the observation group were significantly reduced （P<0.05）. The level of FPG in the observation group was significantly improved compared with that in the control group （P<0.01）. After treatment， the total score of TCM syndromes in the two groups decreased significantly （P<0.01）. Compared with the control group， the total score of TCM syndromes in the observation group was lower （P<0.01）. After treatment， the total effective rate of treatment was 86.67% （26/30） in the observation group and 73.33% （22/30） in the control group. By rank sum test， the total effective rate of the observation group was better than that of the control group （Z=-2.100， P<0.05）. ConclusionModified Cangfu Daotantang combined with basic treatment can effectively reduce the BMI of obese children and improve their glucose and lipid metabolism. It has good clinical effects and high clinical application value， which is worth further in-depth research and promotion.

Simple obesity of stomach heat and damp obstruction treated with acupoint thread embedding therapy: a randomized controlled trial / 中国针灸

OBJECTIVE@#To explore the therapeutic effect and safety of acupoint thread embedding therapy in treatment of simple obesity of stomach heat and damp obstruction.@*METHODS@#A total of 144 patients with simple obesity of stomach heat and damp obstruction were randomized into an acupoint thread embedding group (72 cases, 3 cases dropped off and 1 case removed) and a sham-embedding group (72 cases, 6 cases dropped off and 3 cases removed). On the base of the lifestyle adjustment, the acupoint thread embedding therapy with PGLA thread was applied to Tianshu (ST 25), Zhongwan (CV 12), Ganshu (BL 18), Shuidao (ST 28), etc. in the acupoint thread embedding group, while in the sham-embedding group, the acupoint selection and operation were all same as the acupoint thread embedding group, but without PGLA thread embedded. In either group, the treatment was given once every 2 weeks, consecutively for 12 weeks and the follow-up was conducted for 3 months after treatment. Separately, before and after treatment as well as in follow-up, the obesity indices (body mass index [BMI], waist circumference [WC], waist-to-hip ratio [WHR] and fat percentage [F%]) were observed in the two groups. Before and after treatment, the indices of blood glucose and insulin (fasting blood glucose [FBG], fasting insulin [FINS] and insulin resistance index [HOMA-IR]), adipocyte factor indices (adiponectin, leptin [LP] and serine protease inhibitor [Vaspin]) and inflammatory factor indices (tumor nercosis factor [TNF-α], interleukin-1β [IL-1β] and interleukin-6 [IL-6]) were observed separately in the two groups. The therapeutic effect and safety were compared between the two groups.@*RESULTS@#After treatment and in follow-up, except WC and WHR in the sham-embedding group, BMI, WC, WHR and F% were all reduced as compared with those before treatment in the two groups (P<0.01, P<0.05), and the values in the acupoint thread embedding group were lower than the sham-embedding group (P<0.01). After treatment, except FBG, LP and Vaspin in the sham-embedding group, FBG, FINS, HOMA-IR, LP and Vaspin were all reduced as compared with those before treatment in the two groups (P<0.01, P<0.05), and adiponectin was increased as compared with that before treatment (P<0.01, P<0.05); the improvements in the acupoint thread embedding group were more significant than the sham-embedding group (P<0.01). After treatment, the levels of serum TNF-α, IL-1β and IL-6 in the acupoint thread embedding group were reduced as compared with the values before treatment and those in the sham-embedding group separately (P<0.01). The total effective rate was 89.7% (61/68) in the acupoint thread embedding group, higher than 19.0% (12/63) in the sham-embedding group (P<0.01). There was no severe adverse reaction reported in the two groups.@*CONCLUSION@#Acupoint thread embedding therapy with PGLA thread can alleviate obesity, regulate glucose metabolism and adipocyte factors activity, improve insulin resistance and inhibit the expression of pro-inflammatory factors in the patients with simple obesity with stomach heat and damp obstruction, and this therapy presents a satisfactory safety in treatment.

Analysing the defect of control design of acupuncture: taking RCTs of treating simple obesity with acupuncture for example / 中国针灸

<p><b>OBJECTIVE</b>By analysing the defect of control design in randomized controlled trials (RCTs) of simple obesity treated with acupuncture and using acupuncture as the contrast, presenting the essential factors which should be taken into account as designing the control of clinical trial to further improve the clinical research.</p><p><b>METHODS</b>Setting RCTs of acupuncture treating simple obesity as a example, we searched RCTs of acupuncture treating simple obesity with acupuncture control. According to the characteristics of acupuncture therapy, this research sorted and analysed the control approach of intervention from aspects of acupoint selection, the penetration of needle, the depth of insertion, etc, then calculated the amount of difference factor between the two groups and analyzed the rationality.</p><p><b>RESULTS</b>In 15 RCTs meeting the inclusion criterias, 7 published in English, 8 in Chinese, the amount of difference factors between two groups greater than 1 was 6 (40%), 4 published in English abroad, 2 in Chinese, while only 1 was 9 (60%), 3 published in English, 6 in Chinese.</p><p><b>CONCLUSION</b>Control design of acupuncture in some clinical RCTs is unreasonable for not considering the amount of difference factors between the two groups.</p>

Prescription analysis of electroacupuncture for simple obesity based on complex network technique / 中国针灸

<p><b>OBJECTIVE</b>To analyze the core acupoints and compatibility of electroacupuncture (EA) for simple obesity based on complex network technique, and to explore the usage of EA waveform.</p><p><b>METHODS</b>The clinical research literature regarding EA for simple obesity published from January of 1980 to June of 2016 were searched in PubMed, CNKI, , VIP, CBM and TCM online database to establish a prescription database of EA for simple obesity. The Matlab2014a software was used to perform the center analysis and cluster analysis, and the analysis of core points and compatibility were conducted. Gephi 9.1 software was used to demonstrate the complex network diagram to further analyze the usage of EA waveform.</p><p><b>RESULTS</b>Totally 238 prescriptions were obtained. The selection of acupoints at -meridians were equally important with acupoints at -meridians. The meridians with highest core degree were stomach meridian, conception vessel and spleen meridian. The acupoints with highest core degree were Sanyinjiao (SP 6), Tianshu (ST 25) and Zusanli (ST 36). The cluster analysis indicated three acupoint clusters, including the key-acupoint cluster, syndrome-acupoint cluster, and -point cluster; it was revealed Tianshu (ST 25) and Zhongwan (CV 12) had the highest intensity of compatibility. The sparse-dense wave was mostly used in EA for simple obesity, followed by continuous wave, indicating both sparse-dense wave and continuous wave had high clinical application value.</p><p><b>CONCLUSION</b>The acupoints of EA for simple obesity are mainly in stomach meridian, conception vessel and spleen meridian; sparse-dense wave is mostly used, followed by continuous wave.</p>

Analysis on Randomized Controlled Trials for Acupuncture Treatment of Simple Obesity Collected from PubMed / 针刺研究

OBJECTIVE: To analyze studies published in journals included in PubMed in terms of randomized controlled trials (RCTs) examining the therapeutic effect of acupuncture for simple obesity, so as to provide a reference for subsequent RCT-related designs and results. METHODS: RCT literature about acupuncture treatment of simple obesity from the PubMed database and from 2000 to 2016 was retrieved by using keywords of "obesity" "fat" "acupuncture" "joint application of acupuncture and herbal medicine" or "auricular point" "electroacupuncture", "acupoint application", or "cupping", followed by screening, extraction and evaluation of the design methodology and outcomes using Consolidated Standards for Reporting of Trials (CONSORT) and Standards for Reporting Interventions in Controlled Trials of Acupuncture (STRICTA). RESULTS: Fourteen articles from six countries in Asia examining the therapeutic effect of acupuncture in the treatment of simple obesity mainly by using acupoints of the Stomach Meridian were included. Generally, acupuncture was found to be more effective than sham acupuncture. However, PubMed did not include any RCTs comparing acupuncture with western medicine for weight loss and many problems (as details of needling manipulation, etc.) remained in the the research reports available in the database. CONCLUSION: All the existing RCTs generally affirm the positive efficacy of acupuncture for simple obesity, but high-quality RCTs, particularly those comparing acupuncture with western medicines for weight loss are lacking.

Treatment of Simple Obesity Patients with Phlegm Dampness Stagnation Syndrome with Warming Needle Moxibustion / 针刺研究

OBJECTIVE: To observe the therapeutic effect of warming needle moxibustion stimulation of Hegu (LI 4), Tianshu (ST 25), Zhongwan (CV 12), Zusanli (ST 36), etc. for simple obesity patients with phlegm dampness stagnation syndrome (PDSS)．. METHODS: A total of 60 simple obesity patients with PDSS were equally randomized into control group (13 men and 17 women, 18－53 years in age) and treatment group (14 men and 16 women, 19－45 years in age). All the patients of both groups were treated by diet control (trying their best to reduce high fat, high glucose and high salt foods, supplementing proteins). Patients of the treatment group received additional treatment of warming needle moxibustion, i．e., the inserted acupuncture needles in bilateral Hegu (LI 4), Tianshu (ST 25), Zhongwan (CV 12), and Zusanli (ST 36), Fenglong (ST 40), etc., were manipulated for a while with reducing technique after "deqi"， followed by attachment of ignited moxa-cones at each of the needle handles for 30 min. The treatment was conducted once every other day for 8 weeks. The therapeutic effect was assessed according to the "Criteria for Diagnosis and Therapeutic Effect Evaluation of Simple Obesity" (1998). Before and after the treatment, body fat percentage (F%), body adiposity index (BAI), and body mass index (BMI) were calculated, serum triglyceride (TG), total cholesterol (CHO), low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C) were detected using a biochemical analyzer. RESULTS: Following the treatment, of the two 30 cases of obesity patients in the control and treatment groups, 0 (0.0%) and 1 (3.3%) was under control, 11(36.7%) and 16 (53.3%) had a marked improvement, 8(26.7%) and 10 (33.3%) were effective, and 11 (36.7%) and 3 (10.0%) failed in the treatment, with the effective rates being 63.3% and 90.0%, respectively. The effective rate of the warming needle moxibustion plus diet control was significantly superior to that of the simple diet control (P<0.01). After the treatment, the BMI, F%, serum CHO and TG levels and BAI in the treatment group were significantly decreased in comparison with its own pre-treatment in treatment group (P<0.05, P<0.01), while serum HDL-C of the treatment group was obviously increased compared with its own pre-treatment (P<0.01). The decreased F%, CHO and TG levels were markedly lower in the treatment group than in the control group (P<0.05，P<0.01)．. CONCLUSION: Warming needle moxibustion has a positive effect for simple obesity patients with PDSS in controlling their symptoms.

Clinical Observation on Heat Sensitive Moxibustion in Treating 30 Cases of Simple Obesity with Spleen-kidney Deficiency Type / 中医杂志

Objective To examine the clinical effect of heat sensitive moxibustion in treating simple obesity with spleen-kidney deficiency type.Methods Ninety simple obesity patients with spleen-kidney deficiency type were randomized into a acupuncture group,a heat sensitive moxibustion group and a combination group,with 30 cases in each group.The heat sensitive moxibustion group was given moxibustion by self-made heat sensitive moxa stick.Heat sensitization acupoints were sought at patients' lumbosacral portion and hypogastrium.Two or three heat sensitization acupoints were selected each time.Patients were treated for 5 times each week,each time for 45min.In the acupuncture group,acupoints of Zhongwan (RN12),Shuifen (RN9),Qihai (RN6),Guanyuan (RN4),Mingmen (DU4),Yaoyangguan (DU3),bilateral Tianshu (ST25),Daheng (SP15),Daimai (GB26),Pishu (BL20),Weishu (21) and Shuidao (ST28) were selected.Seven to ten acupoints were selected each time.Even reinforcingreducing method was used.Needle was retained for 30min.During needle retention,manipulating the needles once every 10min.Patients were treated by 5 times each week.The combination group was given both acupuncture and heat sensitive moxibustion.The methods were the same as above.One month was a course.Each group was treated for 3 courses.Patients' body weight,waistline and height were recorded before and after treatment.Body mass index (BMI),body fat percent and waist to height ratio were calculated before and after treatment.The clinical effect was evaluated.Results After treatment,body weight,BMI,body fat percent and waist to height ratio in each group decreased (P ＜ 0.05).After treatment,body weight,BMI,body fat percent and waist to height ratio in the combination group was lower than those in the acupuncture group and the heat sensitive moxibustion group (P ＜ 0.05);while the difference between the acupuncture group and the heat sensitive moxibustion group was not significant (P ＞0.05).The total effective rate in the acupuncture group was 73.3％,with 76.7％ in the heat sensitive moxibustion group,and 86.7％ in the combination group.The clinical effect in the combination group was superior to that in the acupuncture group and in the heat sensitive moxibustion group.Conclusion Heat sensitive moxibustion therapy might be effective in treating simple obesity with spleen-kidney deficiency type.Moreover,the clinical effect seemed better if combined with acupuncture.

Improvement effect of aerobic exercise on haemodynamics and exercise endurance of male old patients with simple obesity / 吉林大学学报(医学版)

Objective:To investigate the effects of 12-week low intensity aerobic exercise on the body composition,haemodynamics and exercise endurance of the male old patients with simple obesity,and to provide evidence for conducting special exercise prescription.Methods:Forty-six male old simple obesity patients were divided into control group (n=19) and exercise group (n=27) according to subjective will.The subjects in control group maintained daily life while those in exercise group performed a 12-week low intensity aerobic exercise.Before and after experiment,the rest heart rates and blood pressures were measured,the maximal oxygen intake (VO2max),maximal power (MP) and exhaust time (ET) were detected by symptom limited graded exercise test,the heart rate curve and blood pressure curve were depicted,and the body composition was determined by body composition analyzer.Results:Compared with before experiment,the fat mass,the percentage of fat body,rest heart rate and blood pressure of the patients in exercise group were decreased (P＜0.05),the VO2 MP and ET were increased (P＜0.05),and the heart rate curve and blood pressure curve during exercise test shifted right;but the indicators in control group showed no significant changes (P＞0.05).Compared with control group,the fat mass,percentage of body fat,rest heart rate and blood pressure were decreased (P＜0.05) and the VO2 MP and ET were increased (P＜ 0.05) in exercise group after experiment.Conclusion:Low intensity aerobic exercise of 12-week may effectively improve the haemodynamic abnormality,reduce the body composition and enhance the exercise endurance.

Application of laparoscopic sleeve gastrectomy in treating simple obesity / 国际外科学杂志

Obesity is becoming an increasingly common health problem in the world.People pay more attention to obesity and the way to lose weight is gradually evolving with the development of science and technology.The widely application of the sleeve gastrectomy in recent years makes the operation has become the world's second-ranked use of weight loss surgery.In this paper,indications and contraindications,surgical methods,surgical results and complications were summarized.

Improvement effect of aerobic exercise on haemodynamics and exercise endurance of male old patients with simple obesity / 吉林大学学报(医学版)

Objective:To investigate the effects of 12-week low intensity aerobic exercise on the body composition,haemodynamics and exercise endurance of the male old patients with simple obesity,and to provide evidence for conducting special exercise prescription.Methods:Forty-six male old simple obesity patients were divided into control group (n=19) and exercise group (n=27) according to subjective will.The subjects in control group maintained daily life while those in exercise group performed a 12-week low intensity aerobic exercise.Before and after experiment,the rest heart rates and blood pressures were measured,the maximal oxygen intake (VO2max),maximal power (MP) and exhaust time (ET) were detected by symptom limited graded exercise test,the heart rate curve and blood pressure curve were depicted,and the body composition was determined by body composition analyzer.Results:Compared with before experiment,the fat mass,the percentage of fat body,rest heart rate and blood pressure of the patients in exercise group were decreased (P＜0.05),the VO2 MP and ET were increased (P＜0.05),and the heart rate curve and blood pressure curve during exercise test shifted right;but the indicators in control group showed no significant changes (P＞0.05).Compared with control group,the fat mass,percentage of body fat,rest heart rate and blood pressure were decreased (P＜0.05) and the VO2 MP and ET were increased (P＜ 0.05) in exercise group after experiment.Conclusion:Low intensity aerobic exercise of 12-week may effectively improve the haemodynamic abnormality,reduce the body composition and enhance the exercise endurance.

Application of laparoscopic sleeve gastrectomy in treating simple obesity / 国际外科学杂志

Obesity is becoming an increasingly common health problem in the world.People pay more attention to obesity and the way to lose weight is gradually evolving with the development of science and technology.The widely application of the sleeve gastrectomy in recent years makes the operation has become the world's second-ranked use of weight loss surgery.In this paper,indications and contraindications,surgical methods,surgical results and complications were summarized.

Clinical Observation of Catgut-embedding Therapy Based on Respiration-induced Reinforcing and Reducing for Treatment of Simple Obesity with Spleen Deficiency and Dampness Retention / 广州中医药大学学报

Objective To observe the therapeutic effect of catgut-embedding (CE) therapy based on respiration-induced reinforcing and reducing and electro-acupuncture (EA) therapy in treating simple obesity with spleen deficiency and dampness retention. Methods Sixty simlpe obesity patients with spleen deficiency and dampness retention were randomized into CE group and EA group, 30 cases in each group. The acupoints selected for the two groups were the same, and the points were Zhongwan, Shuifen, Qihai, Guanyuan, Tianshu, Liangmen, Daheng, Fujie, Quchi, Xuehai, Yinlingquan, Fenglong, and Ashi. CE group was given CE therapy with the needling for CE therapy referred to the respiration-induced reinforcing and reducing method, and EA group was given EA therapy for 2 continuous treatment courses, 4 weeks constituting one course. Body mass and body mass index (BMI) of the two groups before and after treatment were observed, and the clinical efficacy was also evaluated after treatment. Results (1) After treatment for 2 courses, body mass and BMI of the two groups were obviously decreased(P 0.05). (2) The total effective rate of CE group was 90.0% and that of EA group was 86.7%, and the difference between the two groups was insignificant (P > 0.05). Conclusion The therapeutic effect of CE therapy based on respiration-induced reinforcing and reducing in treating simple obesity with spleen deficiency and dampness retention is similar to that of EA therapy, and the patients can choose anyone of them for loosing body weight according to the preference.

Analysis of Composition Principles of Prescriptions for Simple Obesity Based on Traditional Chinese Medicine Inheritance Support System / 广州中医药大学学报

Objective To explore the composition principles of prescriptions for simple obesity based on the analysis of medical literature issued in recently 30 years about Chinese medicine for simple obesity. Methods We collected literature of Chinese medicine in treating simple obesity from VIP, CNKI, Wanfang, CBM and CMCC/CMCI databases, and screened out the formulas for simple obesity to establish a formula database. And then the medication rules were figured out with the Traditional Chinese medicine Inheritance Support System version 2.5 (TCMISS 2.5) software. Results A total of 57 formulas were screened out. And the top 10 herbs with highest occurrence frequency in the prescriptions were Poria, Rhizoma Atractylodis Macrocephalae, Rhizoma Alismatis, Radix et Rhizoma Rhei, Fructus Crataegi, Radix Astragali, Radix Glycyrrhizae, Folium Nelumbinis, Pericarpium Citri Reticulatae and Semen Cassiae. After data mining, we got 13 high-frequency herb-pair combinations and 31 core combinations, and 8 new prescriptions were extracted. Conclusion The research has achieved the quantitative description of the relationship between the Chinese medicines, the extraction of the core combinations and the discovery of new Chinese medicine prescriptions for simple obesity. The results will provide references for the development of new Chinese medicines for the treatment of simple obesity .

Relationship between serum ferritin and nonalcoholic fatty liver diseases in obese children / 中华临床营养杂志

Objective To investigate the relationship between serum ferritin and nonalcoholic fatty liver diseases in obese children.Methods Obese children aged 6 to 14 years old were enrolled.Duration of obesity, anthropometric parameters (height, body weight, waist circumference, hip circumference), bioelectrical impedance analysis (body fat), serological parameters (liver transaminases, lipid metabolism, fasting blood glucose, fasting insulin, serum ferritin) and liver ultrasonography were recorded.Insulin resistance (IR) index was calculated by homeostasis model assessment (HOMA).All subjects were divided into 3 groups according to liver ultrasound and liver transaminases : simple obese children (SOC) group, obese children with nonalcoholic simple fatty liver (NAFL) group and obese children with nonalcoholic steatohepatitis (NASH) group.Results 86 obese children entered the study, with a mean age of (10.4 ± 1.9) years, including 26 in the SOC group, 28 in the NAFL group and 32 in the NASH group.Waist circumference standard deviation score (SDS or Z-score), waist-to-hip ratio, HOMA-IR index and serum ferritin in the NASH group were obviously higher than those in the NAFL group [2.3 ± 0.3 vs.2.1 ± 0.3, P =0.020;1.0 ± 0.0 vs.0.9 ± 0.1,P=0.014;4.0±1.7 vs.2.9±1.8, P=0.006;(104.1 ±49.6) μg/Lvs.(68.4 ±22.7) μg/L, P=0.004] and the SOC group [2.3 ±0.3 vs.1.9 ±0.3, P=0.000;1.0±0.0vs.0.9 ±0.1, P=0.012;4.0 ±1.7 vs.2.5 ±1.6, P=0.001;(104.1 ±49.6) μg/Lvs.(59.2 ±28.9) μg/L, P=0.001], while there was no significant difference in body mass index Z-score [2.8 ± 0.5 vs.2.7 ± 0.6, P =0.524;2.8 ± 0.5 vs.2.7 ± 0.6, P =0.662].There were no significant differences between the NAFL group and the SOC group in the above indicators [2.1 ±0.3 vs.1.9 ±0.3, P =0.260;0.9 ±0.1 vs.0.9 ±0.1, P =0.952;2.9 ± 1.8vs.2.5±1.6, P=0.283;(68.4±22.7) μg/Lvs.(59.2±28.9) μg/L, P=0.161].Mter controlling age, body mass index, waist circumference, waist-to-hip ratio, triglyceride, and HOMA-IR index, serum ferritin was still positively correlated with the magnitude of nonalcoholic fatty liver diseases in obese children (r =0.335, P =0.002).Conclusion Serum ferritin is probably an independent risk factor for NASH in obese children.

Comparison on the efficacy of treatment of children with simple obesity by using comprehensive interventions based on psychotherapy and acupuncture / 中华实用儿科临床杂志

Objective To investigate the efficacy of treatment of children with simple obesity by using comprehensive interventions based on psychotherapy and acupuncture.Methods One hundred and fifty-six cases of simple obesity treated in pediatric clinic were randomly divided into comprehensive intervention group and acupuncture therapy group.Cases in comprehensive intervention group took comprehensive interventions based on psychotherapy,which was on the basis of conventional treatment.Cases in acupuncture therapy group took acupuncture treatment,which was on the basis of conventional treatment.Both groups of exiting cases were recorded.The serum leptin levels of the children between 2 groups were compared before and after treatment.The efficacy was determined based on the circumstances of quality change.The satisfaction of parents in the treatment process and the therapeutic effect were surveyed.Results The good compliance in the comprehensive intervention group was 91.0％,which was significantly higher than that in the acupuncture therapy group(79.5％,x2 =4.131,P =0.042).After 2 months treatment,the serum leptin levels of the male and female in comprehensive group were all lower than those in the acupuncture group(all P ＜ 0.05).The total efficiency of comprehensive intervention group was 91.5％,which was higher than that in the acupuncture therapy group(79.0％,x2 =4.235,P =0.040).The total satisfaction of parents in comprehensive intervention group was 94.4％,which was higher than that in the acupuncture therapy group(82.3 ％,x2 =4.849,P =0.028).Conclusions The therapeutic effect of comprehensive interventions based on psychotherapy for children with simple obesity is better.It helps to improve the compliance of children,and to improve the satisfaction of parents in the treatment process and therapeutic effect.

Meta analysis of trends of simple obesity in children aged 0-7 years old in China / 中华实用儿科临床杂志

Objective To describe the change of obesity incidence over the years by evaluating simple obesity children aged 0-7 years old during 1986 to 2010 in China.Methods Relevant articles were searched for in PubMed,Cochrane Library,Chinese Science Citation Database,CBM,CNKI and Wanfang Database using the key words of "child"," overweight" and "simple obesity" in English and Chinese articles between Jan.1,1980 and Jul.31,2012.A criterion for inclusion was established based on valid criteria for diagnostic research.The eligible studies were collected and analyzed using Stata 10.0.Publication bias was tested by Begg's funnel plot.The heterogeneity test was performed at the same time.The appropriate models was used to calculate prevalence rate and 95％ CI and study gender effect among children.Results Fourteen articles were included with a total of 126 310 children (66 558 boys and 59 752 girls).The rate of child obesity was 4.30％,95％ CI:3.30％-5.40％ ;boys:4.80％,95％ CI:3.60％-6.00％ ;girls:3.70％,95％ CI:2.80％-4.60％.There was no difference between boys and girls in obesity incidence from 1986 to 1995(P ＞0.05),while differences appeared from 1996 to2010(P＜0.05).Conclusions In the 1986 to 2010 period both child obesity incidence and differences between boys and girls continued to increase.The government shall pay attention to such a situation at once and introduce polices to prevent the continuous development of the children simple obesity.

Progress of intervention of child obesity / 国际儿科学杂志

With the improvement of people's living standard,the occurrence of children obesity is also increasing.Children obesity not only affects children' s growth,but also is closely related to the occurrence of many diseases in adults.Therefore,prevention and treatment of child overweight and obesity are very important for improving people's health.This paper summarizes several childhood obesity intervention in recent years.

The Effects of Aerobic Exercises on the Pulmonary Ventilation Function and Electrocardiac Activity of Simple Obesity Primary School Students / 中国运动医学杂志

Objective To investigate the effects of aerobic exercises on the pulmonary ventilation function and electrocardiac activity of simple obesity primary school students. Methods 30 simple obesity boy students were recruited for this study. All the subjects participated in a 12-week aerobic training program (40 min/day,4 days/week). Body composition,pulmonary function and electrocardiogram were tested at the beginning and the end of the training program. Results Decreases of fat mass and body fat ratios were found in response to the exercise stimulus (P<0.05). Free-fat mass(FFM) significantly increased. No statistically significant differences of waist hip ratio (WHR) were found. Among the pulmonary ventilation function indexes,MVV、FEV_1、V_(50)/Ht and PEFR increased significantly (P<0.05, P<0.01). Among the EEG indexes,QTd value and QTcd value decreased significantly (P<0.05,P<0.01). Conclusion Aerobic exercises could improve the pulmonary ventilation function of simple obesity primary school students,and had favorable regulations on electrocardiac activity.

Observation on anricular-point plaster on children with simple obesity / 国际中医中药杂志

Objective To observe effects of auricular-point plaster therapy on children simple obesity.Methods A total of 97 children of simple obesity were treated with auricular-point plaster.Body mass index was measured before and after the treatment.Therapeutic effects and positive changes of auricle were also observed.ResultsBody mass index decreased significantly(P＜0.01)after the treatment as compared to the pre-treatment(t=3.142,P＜0.01).Positive changes of auricle reduced.Auricular-point plaster showed therapeutic effects on obesity in different extents.Conclusion Auricular-point plaster was effective in treating children with simple obesity.

The Influence of Catgut Implantation at Acupoint on Insulin Resistance of Simple Obesity / 国际中医中药杂志

Objective To study the effect of catgut implantation at acupoint on insulin resistance of simple obesity.Methods All patients were separated into the treatment group(catgut implantation group)and the control group(acupuncture group)with 30 cases in each group.Acupoints of zhongwan,tianshu,qihai,shangjuxu,were selected and needled for 3 months.Such indexes as body weight,waistline,hip circumference,body mass index(BMI),fasting blood glucose(FBG),insulin and insulin resistance(IR) before and after treatment were observed.Results Both groups showed obvious anti-obesity effect to simple obesity,manifested by significant differences(P＜0.05)at the indexes of body weight,waistline BMI and appetite before and after treatment.Self-comparison in each group showed such indexes as BFS,insulin and IR were significantly decreased after treatment than those before treatment (P＜0.05)There was no significant difference at the above-mentioned indexes between the two groups(P＞0.05).Conclusions Catgut implantation at acupoint can reduce fat for simple obesity patients by controlling the level of fasting blood sugar,fasting blood insulin and IR in patients.