EXPERIMENTAL STUDIES ON BOLBOSTEMMOSAPONINS USED AS INTRAVAGINAL SPERMATOCIDAL AGENTS / 西安交通大学学报(医学版)

This experiment has proved that bolbostemmosaponin and its constituents A and D have relatively powerful spermatocidal effects. They can kill all spermatozoa in a moment at the concentrations of 0.04%, 0.04% and 0.03% respectively. These spermatocidal agents mainly distroy the biomembrane system of sperm. Using the fixed gelatin membrane technique proved that all of them can strongly inhibit tne activity of a single sperm acrosin at the concentration of 0.05%.