ABSTRACT
Objective To investigate the effect of comprehensive intervention measures on submission of microbiological specimens before therapeutic use of antimicrobial agents.Methods August 2014 to August 2015 was as preintervention group,comprehensive intervention measures were started to carry out from September 2015,Septem ber 2015 to September 2016 was as post-intervention group.Microbiology specimen submission rates before therapeutic antimicrobial use,positive rate of blood culture,and rate of antimicrobial use in all departments and key departments were compared between pre-intervention group and post-intervention group.Results The submission rates of microbiological specimens before general,restricted,and special therapeutic antimicrobial use increased from 42.21％,45.19％,and 74.71％ of pre-intervention respectively to 53.54％,55.68％,and 89.70％ of postintervrntion respectively,showing significant difference (all P＜0.01);after intervention,except gastrointestinal surgery and trauma department of orthopedics,the other departments all met the requirements of the microbiological specimen submission rates set by the hospital;but submission rates of microbiological specimens from department of gastrointestinal surgery and trauma department of orthopedics increased from 5.46％ and 11.67％ before intervention to 11.66％ and 29.45％ respectively after intervention,difference was statistically significant (both P＜0.001).The missing report rate of healthcare-associated infection(HAI) dropped from 13.56％ before intervention to 10.98％ (P＜ 0.05),and the use rate of antimicrobial agents decreased from 57.36％ to 54.47％ (P＜0.001).Conclusion Comprehensive intervention measures can effectively improve the submission rates of microbiological specimens before therapeutic use of antimicrobial agents,reduce missing report rates of HAI and utilization rate of antimicrobial agents,and achieve certain clinical effectiveness.
ABSTRACT
<b>Objective: </b>To reveal the current use of medication notebooks in clinical practice and the differences in submission rates of medication notebooks among patients with different sociodemographic and medical characteristics.<br><b>Methods: </b>We conducted a survey of the submission rates by studying the medication history, from June 19, 2014, to July 3, 2014.<br><b>Results: </b>The overall submission rate of returning patients was 57.1% and the submission rate of patients who visit a single medical institution was significantly lower than patients who visit more than two (55.4% vs. 67.7%, <i>p</i><0.001). Multivariate logistic regression also indicated significant differences between the single and multiple medical institution visit group (adjusted OR=2.74 [95% CI: 1.93-3.89], <i>p</i><0.001). Submission rates for patients in their 20, 30, and 50 s who visit a single medical institution were lower than 40%.<br><b>Conclusions: </b>To improve the usefulness of the community pharmacy and increase the submission rate, we need to increase awareness of the importance of medication notebooks among patients who visit a single medical institution. Additionally, future studies need to focus on factors such as age-related issues that might affect submission rates.
ABSTRACT
Objective To evaluate the clinical application of serum procalcitonin test for diagnosis of sepsis in Xiamen,aimed at observing the application level for serum procalcitonin by different professional clinicians.Methods Retrospectively analyzed the data from 552 specimens collected at three integrated teaching hospitals in Xiamen from July 2012 to October 2013.Patients of sep-sis with positive culture blood were enrolled in the study.All specimens were divided into four groups according to specimen sources,including ICU group,non-ICU group,medicine systems group and surgery systems group.The blood submission rates for procalcitonin detection by different professional clinicians were compared.Results As compared with the non-ICU group,the ICU group had higher submission rate for procalcitonin detection(P < 0.05 ).Medicine systems group had higher submission rate for procalcitonin detection than surgery systems group(P <0.05).Conclusion There is significant difference between professional cli-nicians in procalcitonin application.Surgery clinicians are poor in accepting procalcitonin for diagnosis of sepsis in Xiamen.