CHANGES OF ACTIVITIES OF MITOCHONDRIAL MEMBRANE BINDING ENZYMES IN RATS FED WITH LOW—Se DIET / 西安交通大学学报(医学版)

In this article the activities of succinic dehydrogenase, H~+ -ATPase and creatine kinase in skeletal muscle and heart mitochondria of rats fed with low-Se diet from kashin-beck disease area for 3 to 5 months were observed. The experiments showed that the activities of these three membrane binding enzymes were decreased significantly in mitochondria of rats fed with low-Se diet for 3 to 5 months, as compared to rats suplemented with sodium selenite, but still had not reached the levels in rats fed with diet from Xi'an area.These results suggested that the disturbance of energy metabolism may be induced when the rats fed with low-Se diet for long term.