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@#AIM: To analyze the influence of total femtosecond laser small incision lenticule extraction(SMILE)on corneal surface regularity index(SRI).<p>METHODS:Totally 210(401 eyes)myopic patients treated in Qinhuangdao Optometry Ophthalmology Hospital between January 2017 and December 2019 were enrolled in the study. Among them, patients treated with total femtosecond laser SMILE were included in the observation group(<i>n</i>=110, 205 eyes), while those treated with femtosecond laser-assisted <i>in situ</i> keratomileusis(FS-LASIK)were includded in the control group(<i>n</i>=100, 196 eyes). The uncorrected visual acuity(UCVA), best corrected visual acuity(BCVA), anterior corneal surface asphericity index(Q-value)at a diameter of 6mm and SRI were compared between the two groups before and after operation.<p>RESULTS: The UCVA and BCVA of both groups were improved at 3mo and 6mo after operation(<i>P</i><0.05), without significant differences between the groups(<i>P</i>>0.05). The observation group had higher SRI than the control group at 3mo, 6mo and 1a(<i>P</i><0.05). The asphericity parameter Q-values increased at each time point after operation. Besides, the observation group had lower Q-values than the control group at 6mo and 1a(<i>P</i><0.05).<p>CONCLUSION: Compared with FS-LASIK, SMILE can achieve similar visual recovery effect. However, the SRI is larger after SMILE, and the influence on asphericity index Q-value is less.
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· AIM:To assess the effect of bandage contact lens on the corneal epithelium healing condition,degree of pain and corneal surface after recurrent pterygium excision.· METHODS:Retrospective case-series study.A total of 64 patients (64 eyes) with recurrent pterygium who received treatment in the First Affiliated Hospital of Huzhou University from September 2015 to September 2017 were divided into Group A (34 cases with bandage contact lens group) and Group B (30 cases without bandage contact lens group).The healing status of corneal epithelium was evaluated by fluorescent staining between the two groups at 1d and 1wk after surgery.The degree of pain was assessed between the two groups at 2h,1d and 1wk after recurrent pterygium excision by visual analogue score.Computerized corneal topography was performed on all cases with recurrent pterygium before and 1 mo after successful excision surgery.Statistical analysis of surface regularity index (SRI),surface asymmetry index (SAI) and corneal astigmatism (CA),was done before and 1mo after surgery.· RESULTS:Average scores of corneal epithelium healing condition at 1d and 1wk were better in Group A than that in Group B (P＜0.01).The mean scores of pain values at 2h,1d and 1wk after surgery in Group A were significantly lower than that in Group B respectively (P＜ 0.01).The indicators reflecting corneal surface at 1mo after surgery,including SRI,SAI,CA,were significantly lower in Group A than that in Group B (P＜0.01),while they were not significantly different before surgery between the two groups (P＞0.05).· CONCLUSION:Bandage contact lenses could significantly promote the healing status of corneal epithelium,release pain response and improve corneal refractive status after recurrent pterygium excision.
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Objective To determine the parameters of corneal surface shape and optical quality that affect the results of trial fitting in overnight orthokeratology (OK lenses) in adolescents with myopia.Methods Thirty-eight subjects (67 eyes) who met the inclusion criteria were enrolled in this study.The parameters of corneal surface shape including surface regularity index (SRI),surface asymmetry index (SAI),and Q value were assessed with a corneal topographer before beginning orthokemtology.The Strehl ratio (SR) and the root-mean-square (RMS) of the total higherorder aberrations in a 4-mm pupil were measured before the trial fitting.Participants who had tried orthokeratology were divided into two groups according to the success or failure of trial fitting.Then,we compared the differences in the comeal surface shape and optical quality between the two groups.Results There were 45 eyes in the success group,and 22 eyes in the failure group.There were no statistically significant differences for SRI (P =0.188),SAI (P =0.338),Q value (P =0.657),RMS (P =0.456),and SR (P =0.479) in the two groups.Conclusion The result of trial fitting in orthokemtology is not correlated with the parameters of comeal status and optical quality (SRI,SAI,Q value,RMS,SR).
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?AIM: To evaluate the clinical effects, corneal surface shape and corneal thickness variation after treated by Danzhi Xiaoyao Capsule combined with hypromellose 2910, dextran 70 and glycerol eye drops for dry eye in menopausal patients.?METHODS: Eighty menopausal patients ( 160 eyes ) diagnosed as dry eye were randomly divided into groups A and B ( 40 patients each ) . Group A was treated with hypromellose 2910,dextran 70 and glycerol eye drops only and group B was treated with Danzhi Xiaoyao Capsule and eye drops. Before and 1mo after treatment, the clinical effects were evaluated by symptom scores, fluorescein staining ( FL ) , tear film breakup time ( BUT ) and Schirmer Ⅰ test. While the corneal surface regularity index (SRI), surface asymmetry index (SAI) and central corneal thickness ( CCT) were observed.? RESULTS: At 1mo after treatment, the symptoms scores and FL scores of the 2 groups decreased significantly( P0. 05).?CONCLUSION: Combination therapy of Danzhi Xiaoyao Capsule and hypromellose 2910, dextran 70 and glycerol eye drops for menopausal patients with dry eye is more effective than single eye drops, and can improve the symptoms and signs.