Advances in the Diagnosis and Treatment of Multiple System Atrophy / 罕见病研究

Multiple system atrophy (MSA) is a rare and rapidly-progressive neurodegenerative disorder, characterized by the combination of dysautonomia, poor levodopa responsive parkinsonism, cerebellar ataxia, and pyramidal tract signs. Insidious onset, clinical heterogeneity and progression of the disease complicate the difficulty of early diagnosis and challenge, the development of neuroprotective drugs. In order to improve the knowledge of diagnosis and treatment of the disease, this paper reviews advances in its diagnostic criteria, biomarkers of early diagnosis and management of the disease.

Research progress on oral characterization of Corona Virus Disease 2019 / 口腔疾病防治

@#Corona Virus Disease 2019 (Corona Virus Disease 2019,COVID-19) has become a public health emergency that has attracted global attention because of its large-scale outbreak resulting in numerous human infections and deaths. COVID-19 is a highly contagious respiratory disease caused by novel coronavirus 2019-nCoV. Due to a large number of infections and fast transmission speed, it's significant to diagnose the infected people quickly and detect the asymptomatic infected people as soon as possible. At present, the preliminary screening is judged by the clinical manifestations of the patients, mainly involving the respiratory system, but recent studies have found that the patients infected with COVID-19 have unique oral manifestations, such as taste disturbance, xerostomia, halitosis, inflammation of salivary glands, necrotizing periodontal disease and some of them are earlier than typical symptoms such as dry cough, fever, etc. Paying attention to the oral manifestations of patients can further improve the COVID-19 screening procedure. At present, symptomatic treatment is mainly used for these oral symptoms.

Urinary Tract Infections in Women.

Urinary tract infections (UTIs) are one of the most common bacterial infections seen in primary care, second only to infections of the respiratory tract. Women are particularly at risk of developing UTIs because of their short urethra, and certain behavioral factors which include delay in micturition, sexual activity and the use of diaphragms and spermicides. Uncomplicated UTIs are usually treated empirically with antibiotics. However, not everyone diagnosed with a UTI and treated with an antibiotic will necessarily have a bacterial infection. At least one-half of women who suspect that they have UTI actually do. Studies have shown that one in 7 patients given an antibiotic for UTI symptoms will return within 28 days for a further prescription of antibiotic. Also, many UTIs are self-limiting, improving without treatment even when culture is positive. Symptomatic treatment of uncomplicated UTI may be an option which merits further research. Phenazopyridine is a time-tested urinary tract antiseptic and analgesic that provide symptomatic relief of the pain, burning, frequency and urgency associated with UTI.

A Study in Selection System of Internet Addiction and Harm / 中国医学伦理学

Not everyone who surf on the internet gets addicted and suffers harm of internet addiction,for the selection system of internet addiction and harm involves biological,physiological,behavioral,personal,environmental and sensitivity factors.Internet harm includes physiological harm,psychical harm,society function harm,and the harm for growing-up.Point of exhorting internet addiction lies in internet game addiction,and violent withdrawing approach should be avoided.