ABSTRACT
Objective To investigate the clinical efifcacy of Chinese and western medicine on toxic diffuse goiter (Graves disease) diabetes mellitus. Methods 50 cases of Graves' disease and diabetes mellitus collected in Xianhe hospitol of Dongying city,Shandong Province from June 2010 to June 2011 were randomly divided into observation group(n=25) and control group(n=25). Control group was adopted conventional western medicine treatment. Based on western medicine treatment, observation group was, conducted dialectical types according to TCM theory, and used appropriate Chinese medicine to treatment. Efficacy of two groups after 8 weeks treatment were evaluated. Results The total effective rate in observation group was 90%, higher than 80% in control group(P<0.05). Compared with before treatment, insulin resistance index (HOMA-IR), TT 3, TT 4 levels were signiifcantly decreased, and TSH was signiifcantly increased in both two groups(P<0.01). The improvement of TT 3, TT 4, TSH in treatment group were more obvious than control group, and the difference was signiifcant (P<0.01). Conclusion The combination therapy was effective on patients with Graves' disease and diabetes.
ABSTRACT
Se realizó un estudio de intervención terapéutica en 44 pacientes con bocio tóxico difuso descompensado moderado, atendidos en la Consulta de Endocrinología del Hospital Provincial Docente Clinicoquirúrgico "Saturnino Lora Torres" de Santiago de Cuba, desde marzo del 2008 hasta igual mes del 2010, quienes fueron seleccionados aleatoriamente y luego asignados en 2 grupos de idéntica cantidad de integrantes: el de control, que consumió medicación convencional, y el de estudio, que recibió apiterapia; a fin de determinar la eficacia de la miel de abejas como tratamiento adyuvante. La información fue analizada y procesada mediante las pruebas de hipótesis de Mann Whitney y de comparación de medias, con un error de 5 %, y se obtuvo que la apiterapia resultara más efectiva que la aplicación de los fármacos habituales en la rehabilitación de los afectados, por lo que se sugirió la generalización de su uso a otros servicios de salud.
A study of therapeutic intervention was carried out in 44 patients with moderate descompensated toxic diffuse goiter, assisted in the Endocrinology Department of "Saturnino Lora Torres" Provincial Teaching Clinical-Surgical Hospital in Santiago de Cuba from March, 2008 to same month of 2010, who were randomly selected and then divided into 2 groups of identical number of cases: the control group with conventional medication, and the study group that received bee therapy; in order to determine the effectiveness of honey as auxiliary treatment. The information was analyzed and processed by means of the hypothesis tests of Mann Whitney and that of means comparison, with an error of 5%, and it was obtained that bee therapy was more effective than the application of the habitual drugs in the rehabilitation of those affected, so that the generalization of its use was suggested to other health services.