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The current study involved 70 patients with atopic dermatitis who were treated with herbal medicine at this hospital’s Oriental Medicine department. This study examined a total of 237 prescriptions with Kampo diagnosis used to treat those patients. Patients who no longer needed to use a steroid ointment preparation were defined as “complete responders” and both these patients and patients whose use of a steroid ointment preparation decreased 50% or more from the level prior to use of herbal medicine were defined as “responders.” The complete response rate was the percentage of complete responders and efficacy rate was the percentage of responders. Among all patients, efficacy was 56.3% for unseiin > 50.0% for tokiinshi > 41.0% for Keigairengyoto > others. The complete response rate was 25.0% for unseiin > 16.7% for tokiinshi > 15.8% for shishihakuhito > 13.1% for Keigairengyoto > others. Among patients with “reddish” atopic dermatitis, unseiin had the highest efficacy and resulted in the highest complete response rate, followed by shishihakuhito and then keigairengyoto. Among patients with “wet” atopic dermatitis, unseiin had the highest efficacy and resulted in the highest complete response rate, followed by shofusan. When Kampo diagnosis is equivocal and herbal medicines are urgently needed, unseiin should be the prescription of first choice. Based on the condition of the skin, shofusan, shishihakuhito, or tokiinshi should be the second-best option.
ABSTRACT
Traditional herbal medicine (THM) is an important part of the traditional Chinese medicine culture. Due to its high medicinal potential, it should not only serve for the Chinese people's medical use, but also contribute to the world medicine, THM for the international market must be standardized and large-scale, and produced according to the “Good Agriculture Practice” (GAP). The quality of THM directly affects the patient's treatment status and safety of use. Therefore, the quality assurance of THM runs through the entire process of research and development, production and clinical practice. The standardized production and cultivation of THM is the starting point of the THM industry chain and plays a decisive role in the economic development of the THM industry. This article summarizes the development history, limitations and future development of GAP, and clarifies the opportunities for THM in the rapid development of the international and domestic Chinese medicine industry. In addition, analyzing the deficiencies that were existing in the former GAP implementation process and by suggesting science-based quality measures, it is hoped to stipulate improved GAP guidelines in the future and to lay the foundation for a modern THM international trade.
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The south Indian State of Karnataka, once part of several kingdoms and princely states of repute in the Deccan peninsula, is rich in its historic, cultural and anthropological heritage. The state is the home to 42,48,987 tribal people, of whom 50,870 belong to the primitive group. Although these people represent only 6.95 per cent of the population of the State, there are as many as 50 different tribes notified by the Government of India, living in Karnataka, of which 14 tribes including two primitive ones, are primarily natives of this State. Extreme poverty and neglect over generations have left them in poor state of health and nutrition. Unfortunately, despite efforts from the Government and non-Governmental organizations alike, literature that is available to assess the state of health of these tribes of the region remains scanty. It is however, interesting to note that most of these tribes who had been original natives of the forests of the Western Ghats have been privy to an enormous amount of knowledge about various medicinal plants and their use in traditional/folklore medicine and these practices have been the subject matter of various scientific studies. This article is an attempt to list and map the various tribes of the State of Karnataka and review the studies carried out on the health of these ethnic groups, and the information obtained about the traditional health practices from these people.
ABSTRACT
IntroductionRheumatoid Arthritis (RA) is chronic systemic inflammatory autoimmune disorder that still remains a disease of unknown etiology and complex disease without a single treatment that is dominated by serious and debilitating sequalae resulting from synovial membrane, cartilage and progressive joint destruction involvement. There is a one major obstacle in elucidating the early events in the pathogenesis of RA has been the lack of definition of the initial features of the disease. To overcome these difficulties, various animal models have been developed. But Collagen Induced Arthritis (CIA) mouse model is known to be the most valuable animal model to explore the pathogenic process, molecular and cellular mechanisms of joint destruction, to discover the immune system respond and activation and to develop new effective treatment methods and useful drugs [1].Materials and Methods:Within this study we have used 40 male mice at age 6-8 weeksfor 0-60 days and divided into following 4 groups which are:I group–CIA induced mouse group treated with Derveger Jirgeruu (Saposhnicovia divaricata) (n=12) II group–CIA induced mouse group treated with Natriisalicylas (10%) (n=12) III group–Healthy control mouse group (n=8) IV group–CIA inducedcontrol mouse group (n=8). To induce CIA model, we have used standard method of Murali /2005/’s design. Standard drug Natriisalicylas (10mg/ 20gr), one of the often used drug anti-inflammatory and Mongolian herbal plant Derveger jirgeruu (Saposhnicovia divaricate) (0.26mg/20gr) were daily administered by orally, starting on day 21 until day 60.To evaluate and compare 2 drug’s anti-inflammatory effect, we have done clinical score evaluation (Kim W.U, 2002), laboratory testing and histological examination of the joints using standard methods.ResultTo summarize the research result, both medications have proven to be as a medication which has anti-inflammatory effect that decreased the signs and symptoms of RA by it is histological and laboratory analysis.Conclusions:1. CIA model was effectively induced, which have proven by clinical signs, laboratory result and histological examination.2. Within this study it has proven that traditional herbal medicine Derveger Jirgeruu (Saposhnicovia divaricate) (0.26mg/20g) have anti-inflammatory effect on CIA induced mouse model of Rheumatoid Arthritis, which have had similar effect asstandard non-steroid medicine Natriisalicylas (10mg/20g).
ABSTRACT
OBJETIVO: identificar aspectos relacionados con el uso de las plantas medicinales por quinientos pobladores de Artemisa, provincia La Habana, quienes accedieron de forma voluntaria y con consentimiento informado previo a la aplicación del instrumento, se analizaron variables de interés. MÉTODOS: se realizó un estudio descriptivo, prospectivo, transversal. RESULTADOS: los artemiseños conocen acerca del tema investigado, utilizan un sin número de plantas, muchas de las cuales no tienen su uso autorizado por el MINSAP, no existe un modo de preparación distinguido, la mayoría las emplea para combatir las enfermedades o dolencias ligadas al uso místico-religioso y el principal prescriptor fue el curandero. CONCLUSIONES: se demostró una vez más el poder resolutivo que desde la antigüedad le confieren los humanos a las plantas, ligadas a los rituales místico-religiosos, en nuestra localidad ha llegado hasta nuestros días. El uso de las plantas descritas en el presente trabajo influye de forma directa sobre la vida cotidiana, las costumbres y la salud de la comunidad(AU)
OBJECTIVE: To identify aspects related to the use of medicinal plants by five hundred inhabitants of Artemisa, Havana province, that volunteered to and gave their previous informed consent for the application of the instrument. Some variables of interest were analyzed. METHODS: A descriptional, prospective and cross-sectional study was conducted. RESULTS: The inhabitants of Artemisa know about the research topic. They utilize a great number of plants, whose use is not authorized by the Ministry of Public Health. There is no a specific way to prepare them. Most of them take these plants to fight diseases or ailments related to the mystic-religious use. The healer was the main prescriber. CONCLUSIONS: Once more, it was proved that the resolving power human beings have conferred to plants, linked with mystic-religious rituals, since ancient times, has come to our days in our locality. The use of the plants described in this paper influence directly on the daily life, the customs and the health of the community(AU)
Subject(s)
Humans , Plants, Medicinal/adverse effects , Informed Consent , Medicine, Traditional/methods , Epidemiology, Descriptive , Cross-Sectional Studies , Prospective StudiesABSTRACT
In general EU legislation on pharmaceutical products for human use also applies to herbal medicines.In 2004 EU adopted a Directive to introduce a new pathway for marketing traditional herbal medicinal products,the "simplified registration" procedure.Subject to satisfying certain conditions,it allows the registration of traditional herbal medicinal products without requiring particulars and documents on tests and trials on safety and efficacy,provided that there is sufficient evidence of a minimum 30 years medicinal use,including at least 15 years in the EU.Accordingly pharmaceutical companies should to be able in theory to save considerable expenditure of time,effort and money when applying for marketing authorization.But in practice the new pathway doesn't work out as smoothly as expected.This article analyze the various pieces of European legislation that affect the development of both modern and traditional herbal medicine,the continued growth of their demand,EU's response to the latest market trend,and how Chinese herbal medicine companies should grasp the opportunities to penetrate into the European market.It also stresses the fact that publication of Chinese medicine scientific research articles in international medical journals will be the key to the sector's future success.