ABSTRACT
Objective To explore the effects of L-carnitine on the plasma lipid profile and liver function in elderly patients receiving total parenteral nutrition after abdominal operations.Methods In this prospective blinded randomized controlled trial,24 eligible elderly patients were given 6-day total parenteral nutrition.They were further equally divided into L-carnitine group(administered with L-carnitine 50 mg/kg)and control group(without L-carnitine).The changes of lipid profile and liver function and the clinical outcomes were recorded and compared.Results The plasma triglyeride levels were lower in L-carnitine group than in control group on the 4th and 7th post-operative day,but there were not significant difference(P>0.05);There was a significant difference between the two groups in the change of the 4th post-operative day and pre-operative day(P<0.05).However,the liver function indicators were not significantly different between these two groups.Conclusion Administration of L-carnitine during total parenteral nutrition can improve the triglyeride metabolism in elderly patients after abdominal operations and may benefit the recovery of liver function.
ABSTRACT
Objective To study the correlative clinical factors of hypophosphatemia in the patients of acute myocardial infarction(AMI).Methods According to the plasma phosphonium concentrations,1273 patients with AMI were designed into two groups:Hypophosphatemia Group(serum phosphorus≤0.8 mmol/L),Normal Group.Influence factors of the serum phosphate levels were analyzed.Results The mortality of two groups had no difference.The mobility of hypophosphatemia was higher in the elder patients.The plasma phosphonium concentrations were correlated with the level of TG(r=0.154),and the value of LVEF(r=0.053).Conclusion Hypophosphatemia in patients with AMI is correlated with TG and contractile function.