ABSTRACT
【Objective】 To study and analyze the fluctuation of peripheral blood of apheresis platelet donors aged 56~60, so as to provide data support for safe recruitment and retention of elderly donorsin China. 【Methods】 Elderly apheresisplatelet donors, aged 56~60, donated for 6 769 occasions from 2017 to 2019 in Guangzhou Blood Center were analyzed retrospectively and grouped by gender and age. The fluctuation of peripheral blood was analyzed byone way ANOVA.Further pairwise comparison was carried out by Turky if there were statistical differences. 【Results】 All the peripheral blood levels were statistically significant between men and women aged around 56 (P<0.05). The Plt(×109 / L), RBC(×1012 / L) and Hb(g/L) of women after and before 56 were (274.33±49.47) vs (296.61±44.89), (4.48±0.35) vs (4.4±0.3), and (125.87±9.08) vs (128.33±8.79), respectively, and the differences were statistically significant (P<0.05), while no differences was noticed between them inWBC(×109 / L) and Hct, (6.29±1.36) vs (6.26±1.46) and (0.39±0.05) vs (0.39±0.02), respectively(P>0.05). The RBC(1012 / L), Hb(g/L), WBC(×109 / L) and Hctof men after and before 56 were (4.94±0.39) vs (4.91±0.35), (137.15±12.83) vs (141.29±10.67), (5.77±1.23) vs (6.03±1.26) and (0.42±0.03) vs (0.42±0.03), respectively, and the differences were statistically significant (P<0.05), and no significant difference was noticed in Plt(×109 / L)(283.94±59.63) vs (283.5±62.7)(P>0.05). There was no significant difference in Plt between men and women after 56 (P>0.05). The RBC, Hb and Hct of men around 56 were higher than those of women (P<0.05). The deferral rate of pretransfusion blood testing increased as the platelet donors were older than 56, showing statistical significance(P<0.05). 【Conclusion】 Fluctuation of peripheral blood levelof platelet donors aged 56~60 occurred when they were around 56 years old, but within the normal range.Therefore, blood donation is generally safe under the current policy. As the physiological regulation function of these donors has decreased, the monitoring of peripheral blood routine before and after blood donation needs to be strengthened to ensure blood quality and the health of elderly platelet donors.