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1.
Ciênc. Saúde Colet ; 27(1): 387-398, jan. 2022. tab
Article in English, Portuguese | LILACS | ID: biblio-1356025

ABSTRACT

Resumo O objetivo deste estudo foi descrever as mudanças na frequência do consumo de refeições de adolescentes residentes na região metropolitana do Rio de Janeiro, em período de 5 anos. Utilizaram-se dados de dois estudos transversais, de base populacional, que foram realizados por meio de visitas domiciliares. Em 2005, a amostra final foi de 1089 domicílios com 511 adolescentes (de 12 a 18 anos), e em 2010 de 1121 domicílios com 314 adolescentes. A frequência do consumo de refeições foi obtida por meio de questionário autopreenchido e a avaliação da adequação de peso dos adolescentes foi realizada com base nos pontos de corte do IMC por sexo e faixa etária. Houve aumento da substituição diária do almoço tradicional por lanche (3,7% para 13,7%) e no consumo do jantar tradicional (62,9% para 72,0%). Os adolescentes com sobrepeso consumiram o desjejum com menor frequência do que aqueles sem sobrepeso (2005: 68,3% vs 79,3% p=0,02, 2010: 59,5% vs 77,4% p=0,03). Conclui-se que houve aumento da substituição diária do almoço tradicional por lanche e no consumo do jantar tradicional no período de 5 anos. Ademais, a prática do desjejum diário se associou com a classificação de IMC nos dois momentos do estudo, de modo que aqueles com sobrepeso consomem o desjejum com menor frequência.


Abstract This study described changes in meal frequency over a 5-year period among adolescents living in the Rio de Janeiro metropolitan region. The data used were from two cross-sectional, population-based studies conducted by home visits. In 2005 the final sample was 1089 households with 511 adolescents (aged 12 to 18 years) and in 2010, 1121 households with 314 adolescents. Meal frequency was obtained through self-administered questionnaire and the adolescents were assessed for appropriate weight by BMI cut-off points, by sex and age group. Increasingly, traditional daily lunch was replaced by snacks (from 3.7% to 13.7%) and traditional dinner was eaten (62.9% to 72.0%). Overweight adolescents ate breakfast less often than those not overweight (in 2005, 68.3% and 79.3%, p=0.02 and, in 2010, 59.5% and 77.4%, p=0.03). Traditional daily lunch was increasingly replaced by snacks and consumption of traditional dinner increased over the 5-year period. Also, eating breakfast every day was associated with BMI classification at both study times: those who were overweight consumed breakfast less frequently.


Subject(s)
Humans , Feeding Behavior , Meals , Brazil/epidemiology , Body Mass Index , Cross-Sectional Studies
2.
Revista brasileira de ciência e movimento ; 29(1): [1-9], nov. 2021. tab
Article in Portuguese | LILACS | ID: biblio-1343754

ABSTRACT

As crianças estão cada vez mais utilizando brincadeiras e jogos eletrônicos, passando muitas horas diante da televisão e isso pode atrapalhar o processo de desenvolvimento motor bem como o desenvolvimento do processo de sobrepeso e obesidade. A educação física escolar é um importante aliado na promoção de hábitos de vida mais ativos, sendo a educação infantil a primeira etapa de escolarização e prática de atividades motoras desta fase é fundamental. O objetivo desse estudo foi avaliar o índice de massa corporal (IMC) e o desempenho motor de escolares com idade de cinco anos dos Centros Municipais de Educação Infantil em Divinópolis/MG. O desempenho motor foi avaliado com o Teste de Coordenação Corporal para Crianças (Körperkoodinations test Für Kinder ­ KTK) composto por quatro testes: equilibrar-se andando de costas, saltos monopedais, saltos laterais e transposição lateral sobre plataforma. O IMC foi calculado a partir de medidas de peso e altura. Os resultados do presente estudo demonstram que 80,65% da amostra apresenta deficiência na coordenação motora, e quando comparado entre os sexos, os meninos apresentaram melhor coordenação motora que as meninas. Ao analisar o IMC e a coordenação motora não foi encontrada qualquer relação significativa entre eles. Pode-se concluir com o presente estudo que o IMC não influenciou no desempenho motor dos alunos, e que a maioria dos alunos está com a coordenação motora abaixo do esperado. A falta de aulas de educação física com o professor especialista e estímulos específicos para o desenvolvimento motor podem ter contribuído para os resultados encontrados neste estudo, reforçando a necessidade do professor de educação física n o ensino infantil.(AU)


: Children are increasingly using games and electronic games, spending many hours in front of the television and this can hinder the process of motor development as well as the development of overweight and obesity. School physical education is an important ally in the promotion of more active life habits, with early childhood education being the first stage of schooling and the practice of motor activities in this phase is fundamental. The objective of this study was to evaluate the body mass index (BMI) and the motor performance of schoolchildren aged five years old from the Municipal Centers of Early Childhood Education in Divinópolis / MG. Motor performance was assessed with the Body Coordination Test for Children (Körperkoordinations test Für Kinder - KTK) composed of four tests: balance on your back, single-legged jumps, lateral jumps and lateral transposition on a platform. BMI was calculated from weight and height measurements. The results of the present study showed that 80.65% of the sample has impaired motor coordination, and when compared between genders, boys showed better motor coordination than girls. When analyzing BMI and motor coordination, no significant relationship was found between them. It can be concluded with the present study that the BMI did not influence the motor performance of the students, and that the majority of the students have motor coordination below the expected. The lack of physical education classes with the specialist teacher and specific stimuli for motor development may have contributed to the results found in this study, reinforcing the need for physical education teachers in early childhood education.(AU)


Subject(s)
Humans , Male , Female , Child, Preschool , Physical Education and Training , Body Mass Index , Child Rearing , Motor Activity , Play and Playthings , Psychomotor Performance , Television , Weights and Measures , Child , Child, Preschool , Electronics , Overweight , Internet Addiction Disorder , Habits , Obesity
3.
Arch. endocrinol. metab. (Online) ; 65(4): 455-461, July-Aug. 2021. tab
Article in English | LILACS-Express | LILACS | ID: biblio-1339108

ABSTRACT

ABSTRACT Objective: Obesity and diabetes are the risk factors for cancer development including differentiated thyroid cancer (DTC). Contradictory accumulated data indicates the possible negative effects of obesity and hyperglyceamia as a factor for aggressiveness of DTC. The aim of the present study is to investigate the association of high body mass index (BMI) and presence of type 2 diabetes mellitus (T2DM) on the histological aggressiveness and clinical outcomes in DTC patients followed for over 4 years in a single center. Materials and methods: Consequative 526 DTC patients who had undergone total thyroidectomy and/or radioactive iodine (RAI) ablation were reviewed retrospectively. Patients were divided into groups based on their BMI: normal weight, overweight, obese and also were evalauted in 3 groups presence of diabetes, prediabetes and nomoglyceamia. Histological aggressiveness of DTC at the time of diagnosis and clinical response at the time of last clinical visit were reassessed according to the criteria suggested by ATA 2015 guideline. Results: No differences in histopathologic features, risk of recurrence, cumulative dose of RAI ablation and prevalence of 131I avid metastatic disease were demonstrated among the groups both classified according to BMI and hyperglycemia. Mean of 3.4 year follow-up also showed no differences in the clinial repsonse to therapy and percentage of nonthyroid primary cancer in DTC patients. Conclusion: In this retrospective study we demonstrated that obesity and T2DM have no additive effect on DTC aggressiveness and response to therapy. DTC patients with obesity and diabetes can be treated according to present guidelines without requirement for spesific attention.

4.
Hematol., Transfus. Cell Ther. (Impr.) ; 43(2): 141-146, Apr.-June 2021. tab, graf
Article in English | LILACS | ID: biblio-1286688

ABSTRACT

ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common malignancy in children characterized by the overproduction and accumulation of immature lymphoid cells in the bone marrow and peripheral blood. The BMI-1 is an important component of the Polycomb Repressive Complex-1 (PRC1). It is an important molecule for the self-renewal of hematopoietic stem cells (HSCs). The BMI-1 expression is generally high in HSCs and decreases after cell differentiation. The BMI-1 is required for the maintenance of normal and cancer stem cells and has been reported as an oncogene in various tumors. The NANOG is a homeodomain transcription factor responsible for maintaining the stem cell compartment at the blastocyst stage of developing embryos. The NANOG gene has been proven to be transcribed in CD34+ cells and different leukemic cells. Methods The ribonucleic acid (RNA) was extracted from the peripheral blood mononuclear cells (PBMNCs) of 30 pediatric ALL patients (16 B-ALL and 14 T-ALL) and 14 healthy controls. The Bmi-1 and NANOG expression levels were determined using the quantitative real-time reverse transcription polymerase chain reaction (qRT-PCR). Results Compared to normal controls, patients with ALL exhibited upregulated levels of Bmi-1 (p = 0.03). Patients who overexpressed Bmi-1 and NANOG displayed a significantly worse survival than low-expressing patients (hazard ratio (HR) 5.74, 95% confidence interval (CI):1.48-22, p = 0.012 and HR 3.8, 95% CI:1.009-14.3, p = 0.048, respectively). Conclusions Taken together, these data suggest that the Bmi-1 and NANOG might serve as a novel survival predictor in ALL patients. Our observation also suggests that the Bmi-1 and NANOG could serve as new therapeutic targets for treatment of pediatric ALL.


Subject(s)
Humans , Male , Female , Precursor Cell Lymphoblastic Leukemia-Lymphoma , Real-Time Polymerase Chain Reaction , Polycomb-Group Proteins , Polycomb Repressive Complex 1 , Nanog Homeobox Protein
5.
Multimed (Granma) ; 25(3): e2317, tab
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1279472

ABSTRACT

RESUMEN El cáncer de próstata suele diagnosticarse tardíamente en obesos debido a que el exceso de tejido adiposo dificulta la detección del tumor al interferir en la exploración física (dificultad para realizar el tacto rectal) y en la confiabilidad de exámenes de diagnóstico complementarios como el Antígeno Prostático Específico (PSA, por sus siglas en inglés), retardando de esta forma la realización de la biopsia prostática. Con el objetivo de identificar la relación entre la obesidad y la agresividad del cáncer de próstata al momento de su diagnóstico, se realizó un estudio transversal, analítico en 136 pacientes diagnosticados con cáncer de próstata mediante biopsia transrectal, en el Hospital Provincial "Carlos Manuel de Céspedes", de Bayamo, Granma, Cuba, desde el 1ro de enero de 2018 hasta el 31 de diciembre de 2020. El análisis de asociación entre las variables (Índice de Masa Corporal [IMC], PSA, Suma de Gleason y Estadio Clínico) se realizó a través de la prueba de Tukey y la U de Mann-Whitney. La edad promedio de los pacientes fue de 66,1 años. No se encontró asociación significativa entre el PSA y el IMC (p > 0,05), sin embargo, el valor del PSA mostró una tendencia a disminuir en la medida que aumentó el IMC. La suma de Gleason y el Estadio Clínico mostraron una asociación directa con el IMC, (p<0,003) y (p=0.000) respectivamente. Los pacientes con sobrepeso y obesidad fueron más propensos a presentar valores de PSA más bajos y mayor Gleason, manifestándose en estos un mayor riesgo de cáncer de próstata agresivo al momento del diagnóstico.


ABSTRACT Prostate cancer is often diagnosed late in obese because excess adipose tissue makes it difficult to detect the tumor by interfering with physical examination (difficulty performing rectal touch) and the reliability of complementary diagnostic tests such as Psa, the delaying prostate biopsy. In order to identify the relationship between obesity and the aggressiveness of prostate cancer at the time of diagnosis, a cross-sectional, analytical study was conducted in 136 patients diagnosed with prostate cancer by transrectal biopsy, at the Provincial Hospital "Carlos Manuel de Céspedes", Bayamo, Granma, Cuba, from January 1, 2018 to December 31, 2020. The association analysis between the variables (Body Mass Index [BMI], PSA, Gleason Sum and Clinical Stage) was performed through the Mann-Whitney Tukey and U test. The average age of patients was 66.1 years. No significant association was found between PSA and BMI (p > 0.05), however, the psa value showed a tendency to decrease as BMI increased. The sum of Gleason and the Clinical Stadium showed a direct association with BMI, (p<0.003) and (p-0.000) respectively. Overweight and obese patients were more likely to develop lower PSA and higher Gleason values, with an increased risk of aggressive prostate cancer at the time of diagnosis.


RESUMO O câncer de próstata é frequentemente diagnosticado tardiamente em obesidade porque o excesso de tecido adiposo dificulta a detecção do tumor interferindo no exame físico (dificuldade em realizar o toque retal) e a confiabilidade de exames diagnósticos complementares como psa, a biópsia da próstata retardando. Como objetivo de identificar a relação entre obesidade e agressividade do câncer de próstata no momento do diagnóstico, foi realizado umestudo transversal e analítico em 136 pacientes diagnosticados comcâncer de próstata por biópsiatransretal, no Hospital Provincial "Carlos Manuel de Céspedes", bayamo, Granma, Cuba, de 1º de janeiro de 2018 a 31 de dezembro de 2020. A análise de associação entre as variáveis (Índice de Massa Corporal [IMC], PSA, Gleason Sum e Estágio Clínico) foi realizada através do teste Mann-WhitneyTukey e U. A idademédia dos pacientes foi de 66,1 anos. Nãofoi encontrada associação significativa entre PSA e IMC (p > 0,05), porém, o valor do PSA apresentou tendência a diminuir à medida que o IMC aumentou. A soma de Gleason e do Estádio Clínico mostrou associação direta com o IMC, (p<0.003) e (p-0,000), respectivamente. Pacientes com sobrepeso e obesidade foram mais propensos a desenvolver menores valores de PSA e Gleason mais elevados, commaior risco de câncer agressivo de próstata no momento do diagnóstico.

6.
Rev. cuba. med. mil ; 50(1): e1070, 2021. tab, graf
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1289499

ABSTRACT

RESUMEN Introducción: El entrenamiento físico en la formación militar tiene por objetivo desarrollar la preparación física y psicológica frente a condiciones ambientales adversas. Objetivo: Determinar los cambios en la composición corporal y el somatotipo, producto del periodo de entrenamiento físico básico, en la formación militar de cuatro semanas de duración en soldados conscriptos. Método: Se evaluaron 28 varones (edad: 18,9 ± 0,9 años; estatura: 1,75 ± 0,1 m; masa corporal: 67 ± 8,7 kg; índice de masa corporal: 22,5 ± 2,4 y 70,88 ± 26,57 de ∑6 pliegues) que ingresaron al periodo de formación militar en la Fuerza Aérea de Chile, Base Quintero. Se entregó un consentimiento informado previo a la realización del estudio y se siguieron las indicaciones establecidas en la declaraciónn de Helsinki. Los participantes fueron sometidos a un plan de entrenamiento físico con una duración de 4 semanas, en las instalaciones del centro militar. Resultados: Con posterioridad al entrenamiento físico, hubo una disminución significativa de la masa adiposa (p < 0,01), con un aumento de la masa muscular (p < 0,01). No se observaron diferencias significativas en los componentes del somatotipo (Pre: 3,29 - 4,78 - 2,59 vs. Post: 2,73 - 4,72 - 2,73; p = 0,24). Conclusiones: Se concluye que el entrenamiento físico en militares, durante un periodo corto de cuatro semanas, provoca cambios rápidos y significativos en la composición corporal de los soldados; cambios que no alcanzaron a observarse en el somatotipo.


ABSTRACT Introduction: The objective of physical training in military training is to develop physical and psychological preparation in adverse environmental conditions. Objective: Determine the changes in body composition and somatotype product of basic physical training in military training for four weeks in conscript soldiers. Methods: 28 men were evaluated (age: 18.9 ± 0.9 years; height: 1.75 ± 0.1 m; weight: 67 ± 8.7 kg; BMI: 22.5 ± 2.4 and ∑6 folds 70.88 ± 26.57) who entered the period of military training in the Chilean Air Force, Quintero headquarters. Informed consent was given before the study; the indications established in the Declaration of Helsinki were followed. The participants were incorporated into a physical training plan for 4 weeks. The program was carried out in the facilities of a military center. Results: After physical training there was a significant decrease in adipose mass (p<0.01) and an increase in muscle mass (p<0.01). There were no significant differences in the somatotype components (Pre: 3.29-4.78-2.59 vs. Post: 2.73-4.72-2.73; p = 0.24). Conclusion: It is concluded that physical training in the military, during a short period of four weeks, causes rapid and significant changes in the body composition of the subjects that are not observed with such clarity through the somatotype.

7.
Article in Chinese | WPRIM | ID: wpr-906619

ABSTRACT

Objective To analyze the growth and development of children aged 6 to 14 years in Yangzhou City, Jiangsu Province, and to provide a basis for the evaluation of the growth and development and health care of local children. Methods In November 2020, a stratified cluster sampling method was used to investigate the physical development of 11 026 children aged 6 to 14 years in 9 primary and middle schools in Yangzhou. The results were compared with the current national standards in China. Results The BMI levels of children of all ages from 6 to 14 years in Yangzhou were higher than the national levels (t=6.947~20.093, P<0.01). The heights of boys and girls were relatively close at pre-school age (t=1.348, P=0.025). Boys were slightly taller than girls at the ages of 6 to 8 and 10 to 11 years. At the ages of 9 and 12, girls were slightly taller than boys. Adolescent boys were significantly taller than girls. (t=15.161, P<0.01). Conclusion In Yangzhou City, the height and weight development of students aged 6-14 years conform to the general growth and development trend, and their BMI is generally higher than the national average level.

8.
Journal of Medical Biomechanics ; (6): E415-E422, 2021.
Article in Chinese | WPRIM | ID: wpr-904417

ABSTRACT

Objective To compare the biomechanical characteristics of lower limbs of young people with different body mass index (BMI) before and after the intervention of Baduanjin exercise, so as to provide references for scientific exercise and sport prescription for young Baduanjin practitioners with different BMIs. Methods Young volunteers with different BMI were divided into standard group, overweight group and obesity group. The BTS SMART 3D infrared motion capture system was used to capture the motion parameters and electromyography (EMG) parameters, the KISTLER dynamometer was used to collect the dynamic parameters, the AnyBody simulation software was used to calculate the kinematic parameters and dynamic parameters, and BTS SMART Analyzer was used to compare the different integral electromyography values. Results There was no significant difference in each parameter before the intervention of Baduanjin. After the intervention, the angle and angular velocity of the knee joint during extension and flexion in standard group, overweight group and obesity group, and the angular acceleration of the knee joint during extension and flexion in standard group significantly increased. Baduanjin significantly increased the knee flexion force and moment in standard group, overweight group and obesity group, and increased the hip flexion force and moment as well as ankle metatarsal flexion force and moment in standard group. Compared with obesity group, the knee flexion force and moment in standard group were significantly different. The knee joint force and moment were positively correlated with BMI. Baduanjin significantly increased muscle strength of iliopsoas, gluteus medius, piriformis, gluteus maximus, rectus femoris, sartorius, tibialis anterior, biceps femoris longhead, flexor digitorum longus, flexor pollicis longus, musculus peroneus longus and musculus peroneus brevis. Baduanjin significantly increased the integrated electromyogram (iEMG) of rectus femoris, tibialis anterior, biceps femoris. Conclusions Baduanjin can improve muscle strength and neuromuscular control ability of young people. The larger the BMI, the greater the flexion force and moment of the knee joint.

9.
Article in English | WPRIM | ID: wpr-881407

ABSTRACT

@#Eating disorder (ED) referrals of school age children and adolescents, by their parents and school teachers, have become more common. Also, they are now presenting at an earlier age to the primary health care and school systems, with physical, medical and psychological symptoms. Nevertheless, there is an average of six months to two years between the onset of symptoms to formal assessment and treatment by specialist team. There are also more cases presenting to ED specialist clinic services, especially pre-pubertal children, with early onset and presentation before 14 years old. Mid and late adolescent presentations (after 14 years old) continue to make up more than two third of the cases. More than 60 percent of cases seen in specialist clinics are of the restrictive type anorexia nervosa, and often associated with persistent and excessive exercise. Thirty percent of cases presented are Bulimia nervosa, which tend to be episodic. Majority of single episode bulimia cases do not present themselves early to medical services but take on open source self-directed management. For patients with bulimia who comply to treatment program and recover after 6-12 months of therapy, they can also experience high relapse rate as they often discontinue their follow up. Avoidant-restrictive food intake disorder is more closely related to pre-pubertal onset eating disorder with arrested sexual maturity and growth failure, if left untreated. Psychiatric co-morbidities arising from body image disturbance, overdrive high achievement needs, prior exposure to adverse childhood experiences (ACE), dysfunctional family or peer relationships, include anxiety, avoidance behavior, obsessive rumination, depression, suicidal ideation and attempt. Death can arise from acute presentation and chronic state of ED, when associated with medical complications from refeeding syndrome, severe malnourishment, accidents and suicide. Early identification and assessment by family physicians would significantly improve the prognosis and mitigate against long term chronicity when share care with ED specialist services.

10.
Acta Pharmaceutica Sinica B ; (6): 1274-1285, 2021.
Article in English | WPRIM | ID: wpr-881198

ABSTRACT

Liver is the most common metastatic site for colorectal cancer (CRC), there is no satisfied approach to treat CRC liver metastasis (CRCLM). Here, we investigated the role of a polycomb protein BMI-1 in CRCLM. Immunohistochemical analysis showed that BMI-1 expression in liver metastases was upregulated and associated with T4 stage, invasion depth and right-sided primary tumor. Knockdown

11.
Acta Pharmaceutica Sinica B ; (6): 609-620, 2021.
Article in English | WPRIM | ID: wpr-881159

ABSTRACT

The Hedgehog (HH) signaling pathway plays important roles in gastrointestinal carcinogenesis and the gastrointestinal tumor microenvironment (TME). Aberrant HH signaling activation may accelerate the growth of gastrointestinal tumors and lead to tumor immune tolerance and drug resistance. The interaction between HH signaling and the TME is intimately involved in these processes, for example, tumor growth, tumor immune tolerance, inflammation, and drug resistance. Evidence indicates that inflammatory factors in the TME, such as interleukin 6 (IL-6) and interferon-

12.
Article in Chinese | WPRIM | ID: wpr-886849

ABSTRACT

Objective To analyze the relationship between BMI, physical activity, resting heart rate and diabetes mellitus. Methods A total of 423 patients with diabetes admitted to the Department of endocrinology of our hospital from August 2017 to August 2020 were investigated by questionnaire and physical signs were examined, and the correlation between BMI, physical activity, resting heart rate and diabetes was analyzed. Results FPG, 2 h PG and HbA1c were positively correlated with resting heart rate, BMI and physical activity (P < 0.05). Multiple logistic regression analysis showed that BMI (OR = 2.121), elevated resting heart rate (OR = 1.619) and less physical activity (OR = 0.711) were risk factors for diabetes. Conclusion The increase of BMI and resting heart rate and the decrease of physical activity will increase the risk of diabetes. It is particularly important to prevent the increase of BMI and resting heart rate and increase the physical labor appropriately.

13.
Article in Japanese | WPRIM | ID: wpr-886140

ABSTRACT

The aim of this study was to examine the relationship between deep squatting or ROM of lower limbs, and physical function in typically developing children. 337 elementary school students were recruited for this study. The subjects were performed to squat with their heels down and then were divided into 2 groups: possible squatting and impossible squatting. ROM of lower limbs (hip flexion, knee flexion, and ankle dorsiflexion), circumference of leg, standing long jump, the five-repetition sit-to stand test (FTSST) and a standing test were analyzed. Unpaired t-test or Mann-Whitney U test was used for the two-group comparison. Logistic regression analysis was used to determine variables associated with squatting, and multiple regression analysis was used to determine variables associated with physical function. The rate of impossible squatting was 11.9%. The ROM of the lower limbs was significantly decreased in the impossible group. Multiple regression analysis showed that the ankle dorsiflexion ROM and BMI were correlated with squatting. In physical function, the FTSST and standing test were correlated with squatting. However, in the multiple regression analysis squatting did not significantly affect physical function. In this study, ROM of the ankle dorsiflexion and BMI affected the squatting. It was suggested that the squatting might be useful as a screening for ankle dorsiflexion ROM.

14.
Article in Chinese | WPRIM | ID: wpr-876483

ABSTRACT

Objective To investigate the relationship between BMI and blood lipids, blood glucose and blood uric acid. Methods A total of 3 860 employees from a university who underwent physical examination in 2018 were selected and divided into obesity group, fat group, normal group and lean group according to their body mass index. The levels of blood lipids, fasting blood glucose and blood uric acid among different groups were analyzed and compared. Results There were a total of 1,889 people in the obesity group and fat group, accounting for 48.94% of the total. The weight difference among the different groups was statistically significant (P<0.05), while there was no statistical significance in age difference among different groups. The height in the obese group and fat group was significantly different compared with the normal group. There were significant differences in the levels of triglyceride (TG), high-density lipoprotein (HDL-C) and blood uric acid (UA) in the different groups (P<0.05). The fasting blood glucose level (GLU) in both the obesity group and fat group was significantly different compared with the normal group (P<0.05). With the increase in body weight index, the proportion of high blood fat, fatty liver, hyperglycemia and high blood uric acid all increased significantly as compared with the normal group or the lean group, and the differences were statistically significant (P<0.05). The proportion of fatty liver and hyperuricemia in the male was higher than that in the female. Conclusion The risk of high blood fat, fatty liver, hyperglycemia and hyperuricemia in college faculty and staff was significantly increased with the increase of BMI. It is suggested that the college employees should have a balanced diet, increase exercise, and control BMI within a reasonable range.

15.
Article in English | WPRIM | ID: wpr-875878

ABSTRACT

@#Introduction The new technological innovation can have a vast potential for interventions to help weight loss and combat obesity. The current meta-analysis aimed to compare the effectiveness of smartphone applications (apps) with other methods for promoting weight loss. Methods PubMed, Ovid and Science Direct were searched from 2014 all-inclusive up to May 2019 for relevant studies that assessed any smartphone/mobile phone app intervention with anthropometric measurement. Statistical analysis performed to examine mean difference (95% CI) of body weight, body mass index and waist circumference. Six articles were included for meta-analysis. Findings According to the results, compared with conventional or other interventions, smartphone app interventions showed statistically non-significant decreases in body weight, body mass index and waist circumference. Intervention through smartphone apps alone does not produce substantial evidence of weight loss, even though they might be useful for specific groups. Originality/value There remain prospects to explore regarding the use of smartphone apps in combination with other approaches to aid and promote weight loss, as smartphone use has been proven to influence health-related behavioural modification.

16.
Article in English | WPRIM | ID: wpr-880338

ABSTRACT

Recent studies have revealed an inverse association between height and cardiovascular disease. However, the background mechanism of this association has not yet been clarified. Height has also been reported to be positively associated with cancer. Therefore, well-known cardiovascular risk factors, such as increased oxidative stress and chronic inflammation, are not the best explanations for this inverse association because these risk factors are also related to cancer. However, impaired blood flow is the main pathological problem in cardiovascular disease, while glowing feeding vessels (angiogenesis) are the main characteristic of cancer pathologies. Therefore, endothelial maintenance activity, especially for the productivity of hematopoietic stem cells such as CD34-positive cells, could be associated with the height of an individual because this cell contributes not only to the progression of atherosclerosis but also to the development of angiogenesis. In addition, recent studies have also revealed a close connection between bone marrow activity and endothelial maintenance; bone marrow-derived hematopoietic stem cells contribute towards endothelial maintenance. Since the absolute volume of bone marrow is positively associated with height, height could influence endothelial maintenance activity. Based on these hypotheses, we performed several studies. The aim of this review is not only to discuss the association between height and bone marrow activity, but also to describe the potential mechanism underlying endothelial maintenance. In addition, this review also aims to explain some of the reasons that implicate hypertension as a major risk factor for stroke among the Japanese population. The review also aims to clarify the anthropological reasons behind the high risk of atherosclerosis progression in Japanese individuals with acquired genetic characteristics.


Subject(s)
Aged , Atherosclerosis/physiopathology , Body Height/physiology , Bone Marrow/physiology , Disease Progression , Endothelium/physiology , Humans , Hypertension/physiopathology , Japan/epidemiology , Male , Middle Aged , Risk Factors , Stroke/physiopathology
17.
Arch. endocrinol. metab. (Online) ; 64(6): 704-709, Nov.-Dec. 2020. tab, graf
Article in English | LILACS-Express | LILACS | ID: biblio-1142199

ABSTRACT

ABSTRACT Objective The aim of the study was to assess the long-term impact of laparoscopic sleeve gastrectomy (LSG) on lipid profile, uric acid level and metabolic syndrome. Materials and methods A prospective study was performed between 2009-2014, evaluating long-term percentage of excesso body mass index loss (%EBMIL), lipid profile, uric acid level and metabolic syndrome. Results Overall sixty subjects were followed-up. %EBMIL increased significantly, reaching a maximum (86,9 ± 6,3%) at 5 years post-LSG. Therapeutic success rate (%EBMIL ≥ 60%) was 80% at 5 years. The triglyceride level decreased significantly (148 ± 72.1 mg/dL baseline vs 130.7 ± 57.5 mg/dL at 1 month vs 110.7 ± 42.6 mg/dL at 3 months vs 92.5 ± 35.2 mg/dL at 1 year vs 84.2 ± 32.3 mg/dL at 5 years; p < 0.05 for all). HDL-cholesterol increased and uric acid decreased significantly in the first year postoperatively, remaining stable afterwards (46.9 ± 12.3 mg/dL baseline vs 47.4 ± 10 mg/dL at 1 month vs 49.8 ± 9.3 mg/dL at 3 months vs 55.4 ± 10.2 mg/dL at 1 year; p < 0.05 for all for HDL-cholesterol and 6.4 ± 2 mg/dL baseline vs 6 ± 1.7 mg/dL at 1 month vs 5.2 ± 1.3 mg/dL at 3 months vs 4.8 ± 1 mg/dL at 1 year; p < 0.05 for all for uric acid). The prevalence of metabolic syndrome decreased from 66.7% baseline to 8.3% at 5 years postoperatively (p < 0.01). Conclusions LSG was effective in terms of %EBMIL and metabolic traits improvement for Romanian patients.

18.
Podium (Pinar Río) ; 15(3): 460-473, sept.-dic. 2020. tab, graf
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1143456

ABSTRACT

Resumen Esta investigación caracteriza el índice de masa corporal (IMC) y la Inteligencia Emocional (IE), diferenciada a través de la atención emocional, claridad de sentimientos y reparación de emociones, de un grupo de 120 escolares de Educación básica del Municipio de Soledad, Atlántico, en edad de 11 años. Para la medición de las variables, se han utilizado los valores propuestos para la medición del Índice de Masa Corporal (IMC) en Colombia, como también el cuestionario Trait Meta-Mood Scale-24 (TMMS24), validado para población colombiana. Los resultados de este trabajo muestran a infantes con desnutrición severa, obesidad y sobrepeso, inclinados hacia la dificultad para atender sus emociones, la reparación de sentimientos y el entendimiento de sus emociones. Por lo tanto, resulta pertinente atender dicha problemática en las instituciones mencionadas, puesto que esta puede conllevar a los infantes a padecer de ansiedad y miedo, asociados al bullying, debido a su estado corporal, que han afectado su autoestima y que pueden llegar a ser determinantes para la toma de decisiones, tales como el suicidio.


Resumo Esta investigação caracteriza o índice de massa corporal (IMC) e a Inteligencia Emocional (IE), diferenciada a través de la atención emocional, claridad de sentimientos y reparación de emociones, de un grupo de 120 escolares de Educación básica del Municipio de Soledad, Atlántico, en edad de 11 años. Para a medição das variáveis, utilizam-se os valores propuestos para a medição do Índice de Masa Corporal (IMC) na Colômbia, como también el cuestionario Trait Meta-Mood Scale-24 (TMMS24), validado para población colombiana. Os resultados deste trabajo muestran a infantes con desnutrición severa, obesidad y sobrepeso, inclinados hacia la dificultad para atender sus emociones, la reparación de sentimientos y el entendimiento de sus emociones. Por lo tanto, resulta pertinente atender dicha problemática nas instituições mencionadas, porque esta puede conllevar a los infantes a padecer de ansiedad y miedo, asociados al bullying, debido a su estado corporal, que han afectado su autoestima y que pueden llegar a ser determinantes para la toma de decisiones, tales como el suicidio.


Abstract This research characterizes the body mass index (BMI) and Emotional Intelligence (EI), differentiated through emotional attention, clarity of feelings and repair of emotions, of a group of 120 schoolchildren from Basic Education in the Municipality of Soledad, Atlántico 11 years old. For the measurement of the variables, the values proposed for the measurement of the Body Mass Index (BMI) in Colombia have been used, as well as the Trait Meta-Mood Scale-24 questionnaire (TMMS24), validated for the Colombian population. The results of this work show infants with severe malnutrition, obesity and overweight inclined towards the difficulty to attend to their emotions, the repair of feelings and the understanding of their emotions. Therefore, it is pertinent to address this problem in the aforementioned institutions, since it may lead to infants suffering from anxiety, fear, and others, associated with bullying due to their body condition, which have affected their self-esteem and may reach be decisive for decision-making such as suicide.

19.
Article | IMSEAR | ID: sea-208114

ABSTRACT

Background: Raised body mass index (BMI) and excessive gestational weight gain (GWG) are important determinants in development of gestational diabetes.Methods: A prospective, observational study carried out on antenatal women since their first trimester. These women were screened for gestational diabetes mellitus (GDM) by diabetes in pregnancy study group of India (DIPSI) criteria. All participants were followed up by measuring their BMI, weight gain, blood sugars in every trimester. Also, data was collected regarding any adverse outcomes.Results: Among all participants, 16.8% were diagnosed as GDM. 44% women of study group had weight gain beyond Institute of Medicine (IOM) recommendations. Higher risk of GDM was observed in women with raised BMI and excessive GWG. Also, odds of preeclampsia, preterm deliveries, caesarean section, macrosomia, intrauterine fetal death, neonatal intensive care unit (NICU) admissions were higher in women with GDM.Conclusions: Compliance of recommended weight gain during pregnancy have a strong impact on the fetal outcome. Amount and timing of weight gain plays a crucial role in GDM.

20.
Article | IMSEAR | ID: sea-215846

ABSTRACT

Type2 diabetes mellitus is associated with central obesity. Studies showsthat central obesity, leads to insulin resistance is an important determinant for insulin resistance and cardiovascular morbidity. In the present study clinical profile of type2 diabetics with special reference to cardiac changes were studied and their relationship were established. This is a prospective cross-sectional study conducted in Sree Balaji Medical College and Hospital. 50 obese patients with controlled diabetes less than 5 years of duration were compared with obese non diabetics. There is significant statistical correlation with obese diabetic subjects particularly females, alterations in LV geometry. Obese female subjects had predominantly higher left ventricular mass. From the data of the present study high BMI, WHR have increased incidence of cardiovascular disease

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