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Article in Chinese | WPRIM | ID: wpr-858858

ABSTRACT

OBJECTIVE: To study the effects of rice wine on the metabolism of 3, 29-dibenzoyl karounitriol as the main active component in Gualou-Xiebai in human intestinal flora, exploring the scientific connotation of Gualou-XiebaiBaijiu Decoction from the angle of metabolism. METHODS: The metabolic rate of 3, 29-dibenzoyl karounitriol in Gualou-Xiebai rice wine solution and aqueous solution at different time points were compared,respectively,by intestinal flora experiments. RESULTS: Compared to Gualou-Xiebaiaqueous solution group, the metabolic rate of 3, 29-dibenzoyl karounitriol in Gualou-Xiebai rice wine solution group decreased significantly (P<0.05). CONCLUSION: Rice wine as cites drug can inhibit the metabolism of 3, 29-dibenzoyl karounitriol in Gualou-Xiebai.

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