Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 360
Filter
1.
Invest. educ. enferm ; 40(1): 145-158, 01/03/2022. tab
Article in English | LILACS, BDENF, COLNAL | ID: biblio-1370196

ABSTRACT

Objective. To analyze the process of psychosocial adjustment to illness in a sample of people living with the Human Immunodeficiency Virus from Buenos Aires, Argentina. Methods. Cross-sectional analytical study. The sample consisted of 144 HIV-positive people chosen by simple random sampling. The PAIS-SR questionnaire was used to measure the Psychosocial Adjustment process, which is made up of 46 items organized into 7 domains, whose final score ranges between 0 and 100, interpreted so that the higher the score, the worse the psychosocial adjustment process. Results. The respondents reported were mostly male (82.63%), single (61.80%), with university studies (50.00%), without children (74.30%), and with a steady job (88.19%); the mean age of the participants was 43.8 years. The median global score was 51.4 (IQR: 12). The domains with the worst perception of psychosocial adjustment were: Health care orientation (Me: 56, IQR: 20), extended family relationship (Me: 55, IQR: 20), and Sexual relationship (Me: 54, IQR: 14), while those who had a better perception of adjustment were: Domestic environment (Me: 48, IQR: 8), Psychological distress (Me: 48, IQR: 17), Social environment (Me: 50, IQR: 18) and Vocational environment (Me: 50, IQR: 12). It was found that patients with a poor psychosocial adjustment process had low adherence to treatment, higher frequency of smoking, and sedentary lifestyle (p<0.001), while male sex, older age, and employment were related to a better psychosocial adjustment process (p<0.001). Conclusion. The process of psychosocial adjustment to illness in the study group is medium; adjustment was positively related to self-care habits such as better adherence to pharmacological treatment, physical activity, and not smoking.


Objetivo. Analizar el proceso de ajuste psicosocial en una muestra de personas que conviven con el Virus de la Inmunodeficiencia Humana de la Ciudad Autónoma de Buenos Aires, Argentina. Métodos. Estudio analítico de corte transversal. La muestra estuvo integrada por 144 personas HIV-positivas elegidos mediante muestreo aleatorio simple. Se empleó para la medición del proceso de Ajuste Psicosocial el cuestionario PAIS-SR, el cual está integrado por 46 ítems organizados en 7 dominios, cuyo puntaje final oscila entre 0 y 100, interpretándose de modo que, a mayor puntaje es peor el proceso de ajuste psicosocial. Resultados. Los encuestados fueron en su mayoría sexo masculino (82.63%), solteros (61.80%), con estudios universitarios (50%), sin hijos (74.30%) y con trabajo estable (88.19%); la media de edad de los participantes fue de 43.8 años. La mediana del puntaje global fue de 51.4 (RIQ:12). Los dominios con peor precepción de ajuste psicosocial fueron: Orientación al cuidado de la salud (Me: 56, RIQ: 20), Relación con la Familia Extendida (Me: 55, RIQ: 20) y Relaciones sexuales (Me: 54, RIQ: 14), mientras que los que tuvieron mejor percepción de ajuste fueron: Ambiente familiar (Me: 48, RIQ: 8), Distrés psicológico (Me: 48, RIQ: 17), Ambiente social (Me: 50, RIQ: 18) y Ambiente Laboral (Me: 50, RIQ: 12). Se encontró que los pacientes con un mal proceso de ajuste psicosocial presentaban una baja adherencia al tratamiento y más frecuencia de tabaquismo y sedentarismo (p<0.001), mientras que un mejor proceso de ajuste psicosocial se asoció a ser de sexo masculino, mayor edad y tener empleo estable (p<0.001). Conclusión. El proceso de ajuste psicosocial a la enfermedad en el grupo de estudio es medio; el ajuste se relacionó en forma positiva con hábitos de autocuidado como una mejor adherencia al tratamiento farmacológico, realización de actividad física y no fumar.


Objetivo. Analisar o processo de ajuste psicossocial numa amostra de pessoas que convivem com o Vírus da Imunodeficiência Humana da Cidade Autônoma de Buenos Aires, Argentina. Métodos. Estudo analítico de corte transversal. A amostra esteve integrada por 144 pessoas HIV-positivas elegidos mediante amostragem aleatório simples. Se empregou para a medição do processo de Ajuste Psicossocial o questionário PAIS-SR, o qual está integrado por 46 itens organizados em 7 domínios, cuja pontuação final oscila entre 0 e 100, interpretando-se de modo que, a maior pontuação é pior que o processo de ajuste psicossocial. Resultados. Os entrevistados foram na sua maioria do sexo masculino (82.63%), solteiros (61.80%), com estudos universitários (50%), sem filhos (74.30%) e com trabalho estável (88.19%); a média de idade dos participantes foi de 43 anos. A média da pontuação global foi de 51.4 (RIQ:12). Os domínios com pior percepção de ajuste psicossocial foram: Orientação ao cuidado da saúde (Me: 56, RIQ: 20), Relação com a Família Estendida (Me: 55, RIQ: 20) e Relações sexuais (Me: 54, RIQ: 14), enquanto que os que tiveram melhor percepção de ajuste foram: Ambiente familiar (Me: 48, RIQ: 8), Distresse psicológico (Me: 48, RIQ: 17), Ambiente social (Me: 50, RIQ: 18) e Ambiente Laboral (Me: 50, RIQ: 12). Se encontrou que os pacientes com um mal processo de ajuste psicossocial apresentavam uma baixa aderência ao tratamento e mais frequência de tabaquismo e sedentarismo (p<0.001), enquanto um melhor processo de ajuste social se associou a ser de sexo masculino, maior idade e posse de emprego se relacionaram com um melhor processo de ajuste psicossocial (p<0.001). Conclusão. O processo de ajuste psicossocial à doença no grupo de estudo é médio; o ajuste se relacionou em forma positiva com hábitos de autocuidado como uma melhor aderência ao tratamento farmacológico, realização de atividade física e não fumar.


Subject(s)
Social Adjustment , HIV Infections , HIV-1 , Psychosocial Support Systems , Treatment Adherence and Compliance , Argentina
2.
Saude e pesqui. (Impr.) ; 15(1): e9788, abr./jun. 2022.
Article in Portuguese | LILACS-Express | LILACS | ID: biblio-1368068

ABSTRACT

Objetivou-se analisar a tendência temporal das taxas de incidência dos casos de HIV/Aids no noroeste do Estado do Paraná. Estudo ecológico, de análise de séries temporais com dados referentes às notificações de HIV/Aids na 15ª Regional de Saúde do Estado do Paraná no período de 2009 a 2019. O acesso ao sistema de informação de notificação e agravos ocorreu no mês de junho de 2020. Foi utilizado o teste de Mann-Kendall para verificar a existência de tendência nas séries anuais de casos. A série total apresentou tendência crescente, e o aumento mais expressivo foi em homens (tau de 0,96) acima de 65 anos e de 20 a 34 anos (0,64 e 0,56, respectivamente), com ensino superior e médio (0,89 e 0,78, respectivamente). Não houve aumento significativo nos óbitos. Observou-se crescimento da tendência temporal na maioria das taxas analisadas de incidência dos casos de HIV/Aids.


This study aimed to analyze the temporal trend of incidence rates of HIV/Aids cases in the northwest of the State of Paraná. Ecological study of analysis of time series with data referring to notifications of HIV/Ais in the 15th Regional Health of the State of Paraná, from 2009 to 2019. The access to notification and health problems information system occurred in the month of June 2020. The Mann-Kendall test was used to verify the existence of a trend in the annual case series. The total grade showed an increasing trend, the most significant increase was in men (tau of 0.96), over 65 years old and between 20 and 34 years old (0.64 and 0.56, respectively), with university education and high school (0.89 and 0.78, respectively). There was no significant increase in death rates. There was an increase in the temporal trend in most of the analyzed incidence rates of HIV/Aids cases.

3.
Journal of Clinical Hepatology ; (12): 541-546, 2022.
Article in Chinese | WPRIM | ID: wpr-922950

ABSTRACT

Objective To investigate the efficacy of switching to co-formulated elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/c/F/TAF) combined with sofosbuvir/velpatasvir (SOF/VEL) in the treatment of previously untreated chronic hepatitis C patients with HIV/HCV co-infection and the changes in blood lipid levels. Methods This prospective cohort study was conducted among 10 previously untreated chronic hepatitis C patients with HIV/HCV co-infection who attended Department of Infectious Diseases in Tangdu Hospital from July 2019 to May 2021 and achieved continuous HIV suppression after antiretroviral treatment (ART). As for anti-HIV therapy, the ART regimen was switched to the E/c/F/TAF regimen for 32 weeks, and for anti-HCV therapy, the SOF/VEL regimen was started since week 4 after switching and lasted for 12 weeks. Related indices were monitored before and after switching to E/c/F/TAF for anti-HCV therapy and SOF/VEL for anti-HCV therapy, including body weight, body mass index, HCV genotype, alpha-fetoprotein, liver stiffness measurement, CD4 + T cell count, CD4 + T/CD8 + T ratio, hepatic and renal function parameters, blood lipids, HIV RNA, HCV RNA, SVR12, SVR24, and adverse reactions. The Mann-Whitney U test was used for comparison of continuous data between two groups, and a Spearman correlation analysis was performed. Results After 4 weeks of treatment with E/c/F/TAF, 10 patients (HCV genotypes 2a and 1b) had HIV RNA below the lower limit of detection (20 IU/ml) and a significant reduction in albumin ( Z =-2.801, P =0.003 7), with the other indices remaining stable, and the patients reported significant improvements in the adverse events of anti-HIV therapy with the former ART regimen. After 4 weeks of E/c/F/TAF combined with SOF/VEL, the patients had HCV RNA below the lower limit of detection (15 IU/ml), and both SVR12 and SVR24 reached 100%; after 12 weeks of anti-HCV therapy, there were significant reductions in alanine aminotransferase ( Z =-2.732, P =0.004 8) and aspartate aminotransferase ( Z =-2.501, P =0.010 7) and significant increases in total cholesterol (TC) ( Z =-2.797, P =0.003 9) and low-density lipoprotein cholesterol (LDL-C) ( Z =-2.343, P =0.018 5), with a significantly positive correlation between them ( r =0.87, P < 0.001), and all the other indices were normal. Conclusion For previously untreated chronic hepatitis C patients with HIV/HCV co-infection, switching to E/c/F/TAF combined with SOF/VEL has good efficacy, tolerability, and safety, and the combination of the two regimens can avoid drug interaction, achieve a high HCV cure rate, and maintain HIV suppression. Transient increases in TC and LDL-C are observed during combination treatment, which suggests dyslipidemia caused by HCV infection and the pharmacological action of this regimen.

4.
Infectio ; 25(4): 250-255, oct.-dic. 2021. tab
Article in Spanish | LILACS, COLNAL | ID: biblio-1286718

ABSTRACT

Resumen Introducción: Las alteraciones de la bioquímica hepática son frecuentes en los pacientes con infección por VIH, la etiología es variada, la esteatosis hepática es frecuente con una prevalencia estimada del 60% Objetivos: Caracterizar las alteraciones hepáticas en una serie de pacientes con infección por VIH en un centro de investigación de Bogotá Colombia durante el periodo 2009 - 2019. Materiales y Métodos: Estudio descriptivo, retrospectivo, observacional de pacientes con infección por VIH que asistieron a un centro de investigación durante los años 2009-2019. Resultados: 94% fueron hombres y 6% mujeres con edad promedio de 44 años, 92,5% de los pacientes presentaba uso de terapia antiretroviral. Las principales hepatopatías fueron la coinfección VIH-Hepatitis C y el hígado graso en iguales porcentajes, 31,3%. El promedio del indice HOMA fue de 2,58. Discusión: Las enfermedades hepáticas son una causa importante de morbimortalidad en pacientes con infección por VIH, las coinfecciones virales y el hígado graso pueden ser muy frecuentes en nuestro medio a diferencia de otros estudios Conclusiones: Este es el primer estudio a nivel local en describir las alteraciones hepáticas en pacientes con VIH, las comorbilidades no SIDA, juegan un papel importante dentro de la enfermedad. La hepatitis C continúa siendo una coinfección frecuente en la población VIH.


Abstract Introduction: Alterations in liver biochemistry are frequent in patients with HIV infection, the etiology is varied and includes multiple causes, liver steatosis is one of the most frequent with an estimated prevalence of 60% after the appearance of antiretroviral treatment Objectives: To characterize liver disorders in a series of patients with HIV infection at a research center in Bogotá Colombia during the period 2009-2019. Materials and Methods: Descriptive, retrospective, observational study of patients with HIV infection who attended a disease research center during the years 2009-2019. Results: 67 clinical histories were reviewed, 94% were men and 6% women with an average age of 44 years, 92.5% of the patients had use of anti-retroviral therapy and the diagnosis of HIV was known 11.7 years ago on average. The main liver diseases were HIV-Hepatitis C coinfection and fatty liver in equal percentages, 31.3%. The average HOMA index was 2.58. Discussion: Liver diseases are an important cause of morbidity and mortality in patients with HIV infection. Viral coinfections and fatty liver can be very frequent in our setting, unlike other studies. Conclusions: This is the first study locally to describe the liver disorders in patients with HIV, non-AIDS comorbidities, including fatty liver, play an important role in the disease and could behave like the general population. Hepatitis C continues to be a frequent coinfection in the HIV population.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , HIV Infections , Liver Diseases , Therapeutics , Prevalence , Acquired Immunodeficiency Syndrome , Hepatitis C , Colombia , Fatty Liver , Liver
5.
Biomédica (Bogotá) ; 41(4): 734-744, oct.-dic. 2021. tab
Article in English | LILACS | ID: biblio-1355746

ABSTRACT

Abstract | Introduction: Intestinal apicomplexa protozoa are a recognized cause of gastroenteritis. They are endemic in Honduras and their epidemiology varies in different population groups. Objective: To identify risk factors for cyclosporiasis, cryptosporidiosis, and cystoisosporiasis. Materials and methods: We conducted a case-control study in a hospital-based population. We performed the diagnosis using the modifed Ziehl-Neelsen staining technique and collected the information from laboratory records and clinical charts. Results: Cyclosporiasis was associated with diarrhea (OR=2.28; 95%CI: 1.10-4.89), weight loss (OR=12.7; 95%CI: 2.49-122.00), watery stools (OR=2.42; 95%CI: 1.26-4.65), and infection with another protozoan (OR=3.13; 95%CI: 1.66-5.95). Cryptosporidiosis was associated with HIV infection (OR=15.43; 95%CI: 3.34-71.22), diarrhea (OR=3.52; 95%CI: 1.40-9.40), lymphopenia (OR=6.16; 95%CI: 1.99-18.98), and green color stools (OR=3.00; 95%CI: 1.23-7.30). Cystoisosporiasis was associated with HIV infection (OR=11.20; 95%CI: 3.53-35.44), diarrhea (OR=7.30; 95%CI: 1.89-28.52), leukopenia (OR=4.28; 95%CI: 1.33-13.75), green color stools (OR=11.59; 95%CI: 1.16-558.60), and Charcot-Leyden crystals (OR=11.59; 95%CI: 1.16-558.60). Conclusions: In this hospital-based population from Honduras, HIV infection was a risk factor for cryptosporidiosis and cystoisosporiasis, but not for cyclosporiasis.


Resumen | Introducción. Los protozoos Apicomplexa intestinales son causa reconocida de gastroenteritis. Estas parasitosis son endémicas en Honduras y su epidemiologia varia según los grupos poblacionales. Objetivo. Identifcar los factores de riesgo para ciclosporiasis, criptosporidiosis y cistoisosporiasis. Materiales y métodos. Se hizo un estudio de casos y controles en población hospitalaria. El diagnóstico se hizo utilizando la coloración modifcada de Ziehl-Neelsen. La información se obtuvo del registro de laboratorio y las historias clínicas. Resultados. La ciclosporiasis se asoció con diarrea (OR=2,28; IC95% 1,10-4.89), pérdida de peso (OR=12,7; IC95% 2,49-122), heces líquidas (OR=2,42; IC95% 1,26-4,65), infección con otros protozoos (OR=3,13; IC95% 1,66-5,95). La criptosporidiosis se asoció con el HIV (OR=15,43; IC95% 3,34-71,22), la diarrea (OR=3,52; IC95% 1,40-9,40), la linfopenia (OR=6,16; IC 95% 1,99-18,98), las heces de color verde (OR=3,00; IC95% 1,23-7,30). La cistoisosporiasis se asoció con el HIV (OR=11,20; IC95% 3,53-35,44), la diarrea (OR=7,30; IC95% 1,89-28,52), la leucopenia (OR=4,28; IC95% 1,33-13,75), las heces de color verde (OR=11,59; IC95% 1,16- 558,60), y los cristales de Charcot-Leyden (OR=11,59; IC95% 1,16-558,60). Conclusiones. En este estudio de base hospitalaria en Honduras, el HIV fue un factor de riesgo para la criptosporidiosis y la cistoisosporiasis, pero no así para la ciclosporiasis.


Subject(s)
Honduras , Intestinal Diseases, Parasitic , Parasitic Diseases , Case-Control Studies , HIV Infections , Cryptosporidiosis , Cyclosporiasis
6.
Horiz. meÌüd. ; 21(4): e1671, oct.-dic. 2021. tab, graf
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1356245

ABSTRACT

RESUMEN Objetivo: Evaluar el riesgo de enfermedad cardiovascular a cinco y a diez años en pacientes con infección por VIH en terapia antirretroviral, por medio de las escalas Framingham y Data collection on Adverse Effects of Anti-HIV Drugs Study. Materiales y métodos: Estudio observacional de corte transversal y prospectivo. Se incluyeron pacientes con infección por el VIH en tratamiento antirretroviral de un centro de referencia para pacientes con VIH, entre el 1 de enero y el 30 de abril de 2019. Se realizó evaluación del riesgo cardiovascular a cinco y a diez años a través de los modelos de predicción de Framingham y la escala Data collection on Adverse Effects of Anti-HIV Drugs Study (DAD), y una comparación entre ellos a través de modelos estadísticos. Resultados: Se incluyeron 159 pacientes, con un promedio de edad de 48,90 años ± 9,90. La media de valoración del riesgo cardiovascular por escala de Framingham a 5 años fue de 2,70 % ± 2,80; Framingham a 10 años fue 6,10 % ± 5,70; DAD a 5 años, 3,50 % ± 4,10; DAD a 10 años, de 6,90 % ± 7,70; y el riesgo escala de Framingham a 10 años recalculado para Colombia (multiplicado por 0,75) fue de 4,50 ± 4,20. A través de un modelo de regresión logística, se determinó que la puntuación con mayor número de variables significativamente relacionadas con el resultado de riesgo cardiovascular alto es el modelo DAD a 10 años. Conclusiones: El estudio evidenció una diferencia significativa, con mayor riesgo estimado de enfermedad cardiovascular al utilizar el modelo DAD en comparación con el Framingham, tanto para la estimación a cinco años como a diez.


ABSTRACT Objective: To assess the five- and ten-year cardiovascular disease risk in HIV-positive patients on antiretroviral therapy, using the Framingham risk score and the Data collection on adverse effects of anti-HIV drugs (D:A:D) study. Materials and methods: An observational prospective cross-sectional study. HIV-positive patients on antiretroviral treatment from a referral center for HIV patients were included in the study between January 1 and April 30, 2019. A five- and ten-year cardiovascular risk assessment was performed using the Framingham risk score and the D:A:D study. Additionally, both risk models were compared through statistical models. Results: The study population consisted of 159 patients with a mean age of 48.90 years ± 9.90. The mean cardiovascular risk according to the five-year Framingham risk score was 2.70 % ± 2.80, the ten-year Framingham risk score was 6.10 % ± 5.70, the five-year D:A:D study was 3.50 % ± 4.10, the ten-year D:A:D study was 6.90 % ± 7.70, and the ten-year Framingham risk score recalculated for Colombia (multiplied by 0.75) was 4.50 % ± 4.20. Using a logistic regression model, it was determined that the ten-year D:A:D study provided the greatest number of variables significantly related to a high cardiovascular risk. Conclusions: The study showed a significant difference between the risk models. Both the five- and ten-year D:A:D study provided a better cardiovascular disease risk estimation than the five- and ten-year Framingham model.

7.
An. bras. dermatol ; 96(4): 485-486, July-Aug. 2021. graf
Article in English | LILACS | ID: biblio-1285112

ABSTRACT

Abstract A 56-year-old male, HIV-positive, presented with a 3-day history of multiple indurated erythematous nodules with superficial and well-defined erosions on his right gluteus. Skin biopsy showed ballooning-necrotic keratinocytes and cultures were positive for herpes simplex 2. Genital herpes simplex infection recurrences may not be restricted to the anterior part of the genitalia and clinical presentation in the lumbar area or gluteus must be differentiated from varicella-zoster virus infection. Tumor-like presentation is a very rare manifestation of HSV cutaneous infection. It is important to take this morphological variant into consideration not to delay the diagnosis of a viral infection, especially in an immunosuppressed patient.


Subject(s)
Humans , Male , Herpes Genitalis/diagnosis , HIV Infections/complications , Herpes Simplex/diagnosis , Herpes Zoster , Middle Aged , Neoplasm Recurrence, Local
8.
Ciênc. Saúde Colet ; 26(4): 1346-1354, abr. 2021. tab, graf
Article in English | LILACS | ID: biblio-1285925

ABSTRACT

Abstract The verification of factors associated with growth, body composition and nutritional and nutritional aspects after HIV infection in children or adolescents in Brazil is fundamental for progress in this area. We selected articles published until 2018, available on the platforms PubMed and Lilacs, using the keywords The following descriptors and their associations were used, extracted from MeSH: "Children", "Adolescent", "Anthropometry", "Nutritional Assessment", "HIV", "Brazil" adding the filter "and" for advanced searches. A total of 1,450 articles were found, and after selection and full reading, 19 were selected. The studies agreed that children and adolescents living with HIV present or may present alterations in bone metabolism, lipid metabolism and body composition due to infection or associated with therapy. Significant differences were observed in weight and height in infected infants compared to uninfected infants. The evaluation and monitoring of diet quality, as well as serum micronutrient monitoring, are fundamental to guarantee the clinical and treatment conditions of these patients, as well as to prevent disorders due to low nutrient intakes.


Resumo A verificação de fatores associados ao crescimento, composição corporal e aspectos alimentares e nutricionais, após a infecção pelo HIV em crianças ou adolescentes no Brasil é fundamental para avanços nesta área. Foram selecionados artigos publicados até 2018, disponibilizados nas plataformas PubMed e Lilacs, extraídas do MeSH: "Children", "Adolescent", "Anthropometry", "Nutritional Assessment", "HIV", "Brazil" adicionadas do filtro "and" para as pesquisas. Foram encontrados 1.450 artigos e após seleção e leitura integral foram selecionados 19. Os estudos concordaram que crianças e adolescentes vivendo com HIV apresentam ou podem apresentar alterações no metabolismo ósseo, de lipídeos e na composição corporal devido à infecção ou associadas à terapia. Observou-se diferença significativa do peso e estatura em crianças infectadas em relação às não infectadas. Percebe-se que a avaliação e o monitoramento da qualidade da dieta, bem como o acompanhamento sérico de micronutrientes, são fundamentais para garantir as condições clínicas e de tratamento destes pacientes, bem como para prevenir desordens por baixo consumo de nutrientes.


Subject(s)
Humans , Infant , Child , Adolescent , HIV Infections/drug therapy , Antiretroviral Therapy, Highly Active , Body Weight , Brazil/epidemiology , Nutritional Status
9.
Fisioter. Pesqui. (Online) ; 28(1): 18-24, jan.-mar. 2021. tab
Article in Portuguese | LILACS-Express | LILACS | ID: biblio-1286438

ABSTRACT

RESUMO O objetivo deste estudo foi avaliar a prevalência da síndrome da fragilidade e a sua relação com a função pulmonar, a capacidade funcional e as variáveis relacionadas à pacientes infectados pelo vírus HIV. Trata-se de um estudo transversal e descritivo, com análises quantitativas de dados. A amostra foi composta por indivíduos diagnosticados com HIV/AIDS e sem limitações prévias de locomoção. A síndrome da fragilidade foi avaliada pela aplicação do fenótipo da fragilidade, pontuado nos seguintes itens: perda de peso não intencional, fadiga, redução da velocidade da marcha, redução do nível de atividade física e redução da força de preensão palmar. A função pulmonar e a força muscular ventilatória foram avaliadas por meio de espirometria e manovacuometria. A capacidade funcional foi mensurada pelo teste de caminhada de seis minutos (TC6). A análise dos dados foi realizada com testes estatísticos de comparação, adotando-se o nível de significância de 5%. Todos os pacientes incluídos neste estudo encontravam-se dentro dos critérios de fragilidade. Destes, 70% eram frágeis e 30% pré-frágeis. Verificou-se uma relação entre o comprometimento da capacidade funcional, a prevalência de distúrbio ventilatório restritivo e a presença de comorbidades na população frágil comparado com a pré-frágil. Os achados deste estudo permitem a conclusão de que a síndrome da fragilidade impacta a saúde de indivíduos com HIV/AIDS, com comprometimento da espirometria, redução da capacidade funcional e presença de comorbidades.


RESUMEN El objetivo de este estudio fue evaluar la prevalencia del síndrome de fragilidad y su relación con la capacidad pulmonar, la capacidad funcional y las variables relacionadas a pacientes infectados por el VIH. Este es un estudio transversal y descriptivo, con análisis de datos cuantitativos. La muestra estuvo constituida por personas diagnosticadas con VIH/SIDA y sin limitaciones previas de locomoción. Para evaluar el síndrome de fragilidad, se aplicó el fenotipo de fragilidad, que se puntuó en los siguientes ítems: pérdida de peso involuntaria, fatiga, reducción de la velocidad de la marcha, reducción del nivel de actividad física y reducción de la fuerza de agarre. La capacidad pulmonar y la fuerza de los músculos ventilatorios se evaluaron mediante espirometría y manovacuometría. La capacidad funcional se midió mediante la prueba de caminata de seis minutos (PC6). El análisis de los datos se realizó mediante pruebas de comparación estadística, adoptando un nivel de significancia del 5%. Todos los pacientes incluidos en este estudio se encontraban dentro de los criterios de fragilidad. De estos, el 70% eran frágiles y el 30% prefrágiles. Hubo una relación entre la capacidad funcional deteriorada, la prevalencia de trastorno ventilatorio restrictivo y la presencia de comorbilidades en la población frágil en comparación con la población prefrágil. Los hallazgos de este estudio muestran que el síndrome de fragilidad afecta la salud de las personas con VIH/SIDA, con deterioro de la espirometría, reducción de la capacidad funcional y presencia de comorbilidades.


ABSTRACT This study aims to evaluate the prevalence of frailty syndrome and its relationship with lung function, functional capacity, and disease-related variables in HIV-infected patients. This is a cross-sectional and descriptive study, with quantitative data analysis. The sample consisted of individuals diagnosed with HIV/AIDS, without previous locomotion limitations. The frailty syndrome was evaluated by the frailty phenotype, punctuated in the following items: unintentional weight loss, fatigue, reduced gait speed, physical activity level, and hand grip strength. Pulmonary function and ventilatory muscle strength were assessed by spirometry and manovacuometry, while functional capacity was assessed by the six-minute walk test. Data analyses were performed with comparison tests, with a 5% significance level. All patients included in this study were scored on the frailty criterion. In total, 70% were fragile and 30% were classified as pre-fragile. There was a relation between impaired functional capacity, the prevalence of restrictive ventilatory disorder, and comorbidities in the fragile population when compared with the pre-fragile group. The findings of this study conclude that frailty syndrome affects the health of individuals with HIV/AIDS, with spirometry impairment, reduced functional capacity, and presence of comorbidities.

10.
An. bras. dermatol ; 96(1): 97-99, Jan.-Feb. 2021. graf
Article in English | LILACS | ID: biblio-1152798

ABSTRACT

Abstract Leprosy is a chronic infectious disease caused by Mycobacterium leprae and, depending on the host immune status, presents different clinical forms. This report describes the case of a 46-year-old man who had hypoesthetic lesions in the infrahyoid region for 30 days. The bacilloscopy was negative. The anatomopathological examination showed alterations corresponding to the tuberculoid pole (epithelioid histiocytes) and virchowian pole (foamy histiocytes), compatible with borderline-virchowian leprosy (Ridley and Jopling classification). Rapid tests for HIV I, II, and syphilis were positive, with a CD4 count of 223. The patient started treatment with multibacillary multidrug therapy, antiretroviral therapy, and benzathine penicillin, with marked clinical improvement in two months.


Subject(s)
Humans , Male , Leprosy, Borderline/drug therapy , Leprosy/drug therapy , Drug Therapy, Combination , Leprostatic Agents/therapeutic use , Middle Aged , Mycobacterium leprae
11.
Arch. med ; 21(1): 13-23, 2021/01/03.
Article in English | LILACS | ID: biblio-1148352

ABSTRACT

Objective: to evaluate factors associated with inadequate control of viral load in individuals with Human Immunodeficiency Virus (HIV) in the The Center for Assistance to Sexually Transmitted Infections/SIDA/Viral Hepatitis (CAP) of Itajubá, MG, Brazil. The acquired immunodeficiency syndrome remains a health challenge in Brazil. Therapeutic failures, characterized by detectable viral load, must have their causes evaluated. Among the most relevant reasons is the lack of adherence to treatment. Materials and methods: this is an observational, cross-sectional and documentary study of 261 medical records. The variables analyzed were socio-epidemiological characteristics and laboratory tests for viral load and CD4+ T lymphocytes, poor adherence in history or currently, duration of antiretroviral therapy (ART) use, depression and/or anxiety, use of illicit drugs, follow-up time at the CAP. Results: among the patients, 90.42% had an undetectable viral load and 64.37% had a CD4+ T count ≥500 in the last available test. Some characteristics were related to detectable viral load in the last exam: history of poor adherence during treatment (p<0,0001), inconsistent use of ART (p<0,0001) and use of illicit drugs (p=0,0155). Anxiety and/or depression were not statistically significant (p=0,3321). Conclusion: history of poor adherence, inconsistent use of ART and use of illicit drugs were associated with an increased risk of virologic failure. Early identification of groups at risk of poor adherence to treatment can support the development of intervention strategies in an transdisciplinary way to improve adherence and generate better results in the control of HIV infection..Au


Objetivo: evaluar los factores asociados con el control inadecuado de la carga viral en individuos con virus de inmunodeficiencia humana (VIH) en el Centro de Asistencia para Infecciones de Transmisión Sexual/SIDA/Hepatitis Viral (CAP) de Itajubá, MG, Brazil. El síndrome de inmunodeficiencia adquirida sigue siendo un desafío para la salud en Brasil. Las fallas terapéuticas, caracterizadas por una carga viral detectable, deben tener sus causas evaluadas. Entre las razones más relevantes está la falta de adherencia al tratamiento. Materiales y métodos: estudio observacional, transversal y documental con 261 registros médicos. Las variables analizadas fueron características socioepidemiológicas y pruebas de laboratorio para carga viral y linfocitos T CD4+, pobre adherencia en la historia o en la actualidad, duración del uso de terapia antirretroviral (ARTE), depresión. y/o ansiedad, uso de drogas ilícitas, tiempo de seguimiento en el CAP. Resultados: de los pacientes, el 90.42% tenía una carga viral indetectable y el 64.37% tenía un recuento de CD4 + T ≥500 en la última prueba disponible. Fueron evidenciadas características relacionadas con la carga viral detectable en el último examen: antecedentes de mala adherencia durante el tratamiento (p <0,0001), uso inestable de ARTE (p <0,0001) y uso de drogas ilícitas (p = 0 , 0155). La ansiedad y / o depresión no fue estadísticamente significativa (p = 0.3321). Conclusión: el historial de adherencia deficiente, el uso inconsistente de ART y el uso de drogas ilícitas se asociaron con un mayor riesgo de falla virológica. La identificación de grupos en riesgo de mala adherencia al tratamiento puede ayudar a desarrollar estrategias de intervención de manera temprana y entre disciplinas para mejorar la adherencia y generar mejores resultados en el control de la infección por VIH..Au


Subject(s)
Humans , HIV , Viral Load
12.
Rev. peru. med. exp. salud publica ; 38(1): 166-170, ene-mar 2021.
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1280563

ABSTRACT

RESUMEN La pandemia por la COVID-19 y las medidas restrictivas de distanciamiento social pueden interactuar con la epidemia de VIH de múltiples formas. Existen aproximadamente 87 000 personas viviendo con VIH (PVV) en el Perú quienes están en riesgo de contraer la COVID-19; 67 000 de ellas que reciben tratamiento antirretroviral (TAR) podrían tener limitaciones en el acceso a sus medicamentos, comprometiendo su adherencia y su salud. Además, el efecto que podría tener la pandemia en la salud mental de PVV en Perú aún no está esclarecido. Este artículo tiene como finalidad describir las implicancias clínicas de la coinfección VIH/SARS-CoV-2; discutir los desafíos en la continuidad de atención de las PVV en el Perú durante la crisis sanitaria por la COVID-19; y comentar las posibles implicancias de las medidas restrictivas sobre la salud mental de las PVV.


ABSTRACT The COVID-19 pandemic and societal response implemented may interact with the ongoing HIV epidemic in multiple ways. There are approximately 87000 people living with HIV (PLWH) who are at risk of developing COVID-19 in Peru and 67,000 of them are on antiretroviral therapy (ART) and at risk of limitations in their access to ART, compromising their adherence and their health during the pandemic. Finally, the potential effect of the pandemic on the mental health of PLWH is not documented. This opinion aims to: describe the clinical implications of the HIV/SARS-CoV-2 coinfection; discuss the challenges to the continuity of care of PLWH in Peru during the COVID-19 crisis; and comment possible implications that the COVID-19 crisis may pose on the mental health of PLWH.

13.
Rev. peru. med. exp. salud publica ; 38(1): 166-170, ene-mar 2021.
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1280595

ABSTRACT

RESUMEN La pandemia por la COVID-19 y las medidas restrictivas de distanciamiento social pueden interactuar con la epidemia de VIH de múltiples formas. Existen aproximadamente 87 000 personas viviendo con VIH (PVV) en el Perú quienes están en riesgo de contraer la COVID-19; 67 000 de ellas que reciben tratamiento antirretroviral (TAR) podrían tener limitaciones en el acceso a sus medicamentos, comprometiendo su adherencia y su salud. Además, el efecto que podría tener la pandemia en la salud mental de PVV en Perú aún no está esclarecido. Este artículo tiene como finalidad describir las implicancias clínicas de la coinfección VIH/SARS-CoV-2; discutir los desafíos en la continuidad de atención de las PVV en el Perú durante la crisis sanitaria por la COVID-19; y comentar las posibles implicancias de las medidas restrictivas sobre la salud mental de las PVV.


ABSTRACT The COVID-19 pandemic and societal response implemented may interact with the ongoing HIV epidemic in multiple ways. There are approximately 87000 people living with HIV (PLWH) who are at risk of developing COVID-19 in Peru and 67,000 of them are on antiretroviral therapy (ART) and at risk of limitations in their access to ART, compromising their adherence and their health during the pandemic. Finally, the potential effect of the pandemic on the mental health of PLWH is not documented. This opinion aims to: describe the clinical implications of the HIV/SARS-CoV-2 coinfection; discuss the challenges to the continuity of care of PLWH in Peru during the COVID-19 crisis; and comment possible implications that the COVID-19 crisis may pose on the mental health of PLWH.

14.
Esc. Anna Nery Rev. Enferm ; 25(1): e20190386, 2021. tab
Article in Portuguese | LILACS, BDENF | ID: biblio-1124796

ABSTRACT

RESUMO Objetivo Analisar o discurso dos gerentes saúde relacionado à organização da oferta do teste rápido anti-HIV, na perspectiva do atributo integralidade. Método Pesquisa exploratória de natureza qualitativa realizada em um distrito sanitário do município de João Pessoa/PB. A coleta de dados foi realizada em setembro de 2017, utilizando-se um roteiro de entrevista semiestruturado, o qual foi aplicado a treze gerentes de saúde de serviços de Atenção Primária à Saúde. O material empírico foi analisado à luz do dispositivo teórico-metodológico de Análise de Discurso, identificando-se o bloco discursivo: Organização dos serviços para a realização do teste rápido anti-HIV. Resultados Os discursos apontam a filiação ideológica que compreende a fragmentação da assistência, normatização da demanda com enfoque em agendamentos, estigmatização e desresponsabilização do cuidado, dificultando a realização da integralidade na perspectiva da descentralização da oferta do teste rápido anti-HIV. Conclusão e implicações para a prática O discurso dos gerentes de saúde aponta fragilidades na qualidade do serviço e organização da oferta do teste rápido anti-HIV. Executar as políticas para reverter a situação atual e a educação permanente dos profissionais podem potencializar a integralidade do serviço.


RESUMEN Objetivo Analizar el discurso de los gerentes de la salud relacionados con la organización de la oferta de pruebas rápidas anti-VIH, desde la perspectiva del atributo de integralidad. Método Investigación exploratoria de naturaleza cualitativa, realizada en un distrito sanitario del municipio de João Pessoa/PB. La recogida de datos se llevó a cabo en septiembre de 2017, utilizando un plan de entrevista semiestructurada, que se aplicó a trece gerentes de la salud de servicios de Atención Primaria de la Salud. El material empírico se analizó a la luz del dispositivo metodológico teórico del Análisis del Discurso, identificando el bloqueo discursivo: Organización de servicios para realizar la prueba rápida anti-VIH. Resultados Los discursos señalan la afiliación ideológica que incluye la fragmentación de la asistencia, la normatización de la demanda con enfoque en los horarios, la estigmatización y la irresponsabilidad de la atención, lo que dificulta alcanzar la integralidad desde la perspectiva de la descentralización la oferta de prueba rápida anti-VIH. Conclusión e implicaciones para la práctica El discurso de los gerentes de la salud señala las deficiencias en la calidad del servicio y la organización de la oferta de pruebas rápidas anti -VIH. La implementación de políticas para revertir la situación actual y la educación permanente de los profesionales puede potenciar la integralidad del servicio.


ABSTRACT Objective Analyze health managers discourse related to the organization of the rapid anti-HIV test provision, from the perspective of the integrality attribute. Method Exploratory research of qualitative nature, undertaken in a health district of the municipality of João Pessoa, Paraíba. Data collection was carried out in September 2017, using a semi-structured interview script for a semi-structured interview, which was applied to thirteen health care service managers from Primary Health Care services. The empirical material was analyzed in the light of the theoretical-methodological Discourse Analysis device, identifying the discursive block: Organization of services for conducting the rapid anti-HIV test. Results The speeches point out to the ideological affiliation that comprises the fragmentation of the assistance, standardization of the demand with focus on schedules, stigmatization and unaccountability of the care, making it difficult to achieve comprehensiveness in the perspective of the decentralization of the offer of rapid anti-HIV test. Conclusion and implications for practice The discourse of health managers points out weaknesses in the quality of service and organization of the rapid anti- HIV test provision. Implementing policies to reverse the current situation and continuing education for professionals can enhance the integrality of the service.


Subject(s)
Humans , Male , Female , Primary Health Care/organization & administration , AIDS Serodiagnosis , Integrality in Health , Stereotyping , HIV Infections/diagnosis , Qualitative Research , Early Diagnosis , Health Manager
15.
Rev. Soc. Bras. Med. Trop ; 54: e01572021, 2021. graf
Article in English | LILACS | ID: biblio-1250835

ABSTRACT

Abstract Approximately one-third of patients with coronavirus disease 2019 (COVID-19) present with coagulation disorders and hematological changes. However, the clinical manifestations of COVID-19 and prognoses of people living with human immunodeficiency virus (HIV) remain controversial. This study reports the case of a 27-year-old HIV-infected man who regularly used antiretroviral medications, had no other comorbidities and was admitted for acute respiratory distress syndrome caused by COVID-19. Complementary examinations during hospitalization revealed a diagnosis of pulmonary thromboembolism in association with an intracavitary thrombus.


Subject(s)
Humans , Male , Adult , Pulmonary Embolism/etiology , Thrombosis , HIV Infections/complications , COVID-19 , HIV , SARS-CoV-2
16.
Rev. saúde pública (Online) ; 55: 45, 2021. tab, graf
Article in English | LILACS-Express | LILACS, BBO | ID: biblio-1289973

ABSTRACT

ABSTRACT OBJECTIVE: To verify the effectiveness of screening for tuberculosis (TB) on all-cause mortality and tuberculosis cases in newly diagnosed HIV-infected patients through a clinical algorithm based on recommendations of the World Health Organization. METHODS: From March 2014 to April 2016, a pragmatic randomized clinical trial was conducted with newly diagnosed and TB-free HIV-infected adults undergoing antiretroviral therapy for up to one month at a major tertiary hospital for HIV in the state of Pernambuco, Brazil. Participants were randomized into intervention and control groups using an automatically-generated random list, and followed-up for at least 6 months. The intervention group was screened for TB at hospital admission and at every follow-up visit through a series of questions addressing TB-related symptoms (cough, fever, night sweating, and weight loss). Patients presenting with any of these symptoms were referred to a pulmonologist and underwent sputum smear microscopy, sputum culture, and rapid molecular testing (GeneXpert). When at least one test result came back positive, TB treatment was initiated. In turn, if patients tested negative but presented with severe clinal symptoms, TB preventive treatment was initiated. Screening for TB was not performed systematically in the control group. The primary outcome assessed in this study was death from all causes, and secondary outcomes included sensitivity and specificity of this screening test, as well as its detection time. RESULTS: This study evaluated 581 patients, 377 in the intervention group (64.9%) and 204 in the control group (35.1%). In total, 36 patients died during the follow-up period. Of these, 26 (6.9%) were from the intervention group, reaching a cumulative mortality coefficient of 69 per 1,000 inhabitants, and 10 (4.9%) from the control group (p = 0.341), with a cumulative mortality coefficient of 49 per 1,000 inhabitants (p = 0.341).

17.
Article in English | LILACS | ID: biblio-1283953

ABSTRACT

Introduction: In recent years there has been an increase in the number of AIDS diagnoses in the general population, with a significant growth among elderly individuals. Objective: To analyze the epidemiological situation of AIDS in the elderly population and its temporal trend in the Santa Catarina State. Methods: Ecological study, conducted with the elderly (≥60 years) living in Santa Catarina, who were diagnosed with AIDS and notified in the Brazilian Information System for Notifiable Diseases (SINAN) from 2008 to 2018. The incidence rate according to sex, age group and health macro­region was calculated, as well as the time trend, through linear regression. Race/skin color and scholarity were analyzed by proportion in relation to the total. Results: 1,365 cases were notified from 2008 to 2018. There was an increase in cases from 6,7/100.000 in 2008 to 23,1 in 2018 (1,77% yearly), higher among men aged 60 to 69 and living in the area of Florianópolis. Conclusion: there was an increase in AIDS notifications among the elderly in the state.


Introdução: Nos últimos anos, tem­se observado um aumento no número de diagnósticos de aids na população em geral, entre eles um crescimento expressivo entre indivíduos idosos. Objetivo: Analisar o panorama epidemiológico da aids em idosos no estado catarinense e a tendência temporal dos casos. Métodos: Estudo ecológico, com idosos (≥60 anos) residentes no estado de Santa Catarina que apresentaram o diagnóstico e a notificação de aids no Sistema de Informação de Agravos de Notificação nos anos de 2008 a 2018. Foram calculadas a incidência segundo sexo, faixa etária e macrorregião de saúde de Santa Catarina, bem como a tendência no período, por meio da regressão linear. Para raça/cor e escolaridade, considerou­se a proporção das notificações em relação ao total de casos. Resultados: Foram notificados 1.365 casos no período. A incidência aumentou de 6,7/100.000 em 2008 para 23,1 em 2018 (1,77 pontos percentuais ao ano), sendo maior na faixa etária de 60 a 69 anos, entre homens e residentes na macrorregião da Grande Florianópolis. Conclusão: Verificou­se crescimento das notificações de aids em idosos no estado de Santa Catarina.


Subject(s)
Humans , Aged , Acquired Immunodeficiency Syndrome/epidemiology , Brazil/epidemiology , Sexually Transmitted Diseases , Incidence , Social Factors
18.
Rev. eletrônica enferm ; 23: 1-8, 2021.
Article in English, Portuguese | LILACS, BDENF | ID: biblio-1284227

ABSTRACT

Objetivo: Analisar o perfil epidemiológico da infecção pelo HIV em gestantes indígenas e não indígenas no estado do Pará. Métodos: Estudo epidemiológico, transversal, realizado a partir de dados do Sistema de Informação de Agravos de Notificação referentes ao período de 2010 a 2017. Resultados: As taxas de detecção de HIV em gestantes apresentaram tendência de crescimento nos dois grupos étnicos. O acompanhamento pré-natal mostrou-se importante para a triagem sorológica do HIV nas populações estudadas. Conclusão: Os elevados índices de HIV em gestantes, especialmente entre indígenas, evidenciam a necessidade de adequação da política e diretrizes de prevenção do HIV/aids de modo a torná-las culturalmente adequadas para os diferentes contextos étnicos. Além disso, torna-se imprescindível a ampliação das medidas de prevenção e diagnóstico do HIV em momentos que antecedem a gestação a fim de interromper a cadeia de transmissão do vírus.


Objective: To analyze the epidemiologic profile of HIV infection in indigenous and non-indigenous pregnant women in the state of Para. Methodology: Cross-sectional epidemiologic study based on data from 2010 to 2017 collected from the Sistema de Informação de Agravos de Notificação (System for Notifiable Diseases). Results: HIV detection rates in pregnant women showed a growth trend in both ethnic groups. Prenatal care proved to be essential in the serological screening of HIV in the populations studied. Conclusion: The high rates of HIV among indigenous women point to the need to have culturally appropriate HIV/AIDS prevention policies and guidelines for different ethnic contexts. In addition, HIV prevention and diagnosis measures before pregnancy must be expanded to break the virus chain of infection.


Subject(s)
Pregnancy , HIV Infections , Health of Indigenous Peoples , Social Vulnerability
19.
Esc. Anna Nery Rev. Enferm ; 25(spe): e20210176, 2021. ilus
Article in Portuguese | LILACS, BDENF | ID: biblio-1284230

ABSTRACT

Objetivo: identificar as mudanças na rotina das pessoas vivendo com HIV decorrentes da pandemia da COVID-19. Método: pesquisa qualitativa, desenvolvida por meio de entrevista semiestruturada, junto à 46 pessoas vivendo com HIV atendidas em um serviço especializado em doenças infectocontagiosas do interior de Minas Gerais, Brasil. Os dados foram submetidos à análise lexicográfica, com auxílio do software IRaMuTeQ, pelos métodos de Estatística Textual Clássica, Nuvem de Palavras e Classificação Hierárquica Descendente. Resultados: foram identificadas distintas mudanças na rotina diária de pessoas vivendo com HIV decorrentes da pandemia da COVID-19, dentre elas, o uso de medidas preventivas, como a utilização de máscara e isolamento social, além de mudanças no ambiente de trabalho e de lazer, no convívio familiar, aspectos emocionais individuais e de tratamento. Conclusão e implicações para a prática: muitas mudanças e desafios de ordem física, biológica e psicossocial demonstraram serem vivenciados pelos participantes diante do cenário mundial pandêmico, decorrentes, principalmente, do isolamento social. Para tal, estratégias de enfrentamento tornam-se fundamentais no dia-a-dia das pessoas vivendo com HIV visando garantir a continuidade e tratamento ininterrupto, e a prevenção de uma sindêmia, mitigando, assim, as repercussões da COVID-19 na saúde destes indivíduos que pertencem ao grupo de risco


Objective: to identify the changes in the routine of people living with HIV resulting from the COVID-19 pandemic. Method: a qualitative research study, developed through a semi-structured interview, with 46 people living with HIV treated at a service specialized in infectious diseases in the inland of Minas Gerais, Brazil. The data were submitted to lexicographic analysis, with the aid of the IRaMuTeQ software, using the methods of Classical Textual Statistics, Word Cloud and Descending Hierarchical Classification. Results: distinct changes were identified in the daily routine of people living with HIV due to the COVID-19 pandemic, including the use of preventive measures, such as wearing a mask and social isolation, in addition to changes in the work and leisure environment, in family life, individual emotional aspects and treatment. Conclusion and implications for the practice: many changes, challenges of a physical, biological and psychosocial nature have been shown by the participants in the face of the global pandemic scenario, mainly resulting from social isolation. To this end, coping strategies become essential in the everyday lives of people living with HIV in order to guarantee continuity and uninterrupted treatment, and the prevention of a syndemic, thus mitigating the repercussions of COVID-19 on the health of the individuals who belong to the risk group


Objetivo: identificar los cambios en la rutina de las personas que viven con VIH como resultado de la pandemia de COVID-19. Método: investigación cualitativa, desarrollada a través de una entrevista semiestructurada, con 46 personas que viven con VIH atendidas en un servicio especializado en enfermedades infecciosas en el interior de Minas Gerais, Brasil. Los datos fueron sometidos a análisis lexicográfico, con la ayuda del software IRaMuTeQ, y utilización de los métodos de Estadística Textual Clásica, Nube de Palabras y Clasificación Jerárquica Descendente. Resultados: se identificaron distintos cambios en la rutina diaria de las personas que viven con VIH debido a la pandemia de COVID-19, incluido el uso de medidas preventivas, como la utilización de barbijo y aislamiento social, además de cambios en el entorno laboral y de ocio, en la vida familiar, en aspectos emocionales individuales y en el tratamiento. Conclusión e implicaciones para la práctica: muchos cambios y desafíos de naturaleza física, biológica y psicosocial han atravesado a los participantes ante el escenario de la pandemia global, principalmente debido al aislamiento social. Para ello, las estrategias de afrontamiento se vuelven imprescindibles en el día a día de las personas que viven con VIH a fin de garantizar la continuidad y el tratamiento ininterrumpido, y la prevención de una sindemia, con el objetivo de mitigar las repercusiones del COVID-19 en la salud de estos sujetos que pertenecen al grupo de riesgo


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , HIV Infections , HIV , COVID-19/prevention & control , HIV Infections/drug therapy , Hand Disinfection , Qualitative Research , Anti-Retroviral Agents/therapeutic use , Family Relations , Feeding Behavior , Coinfection/prevention & control , Teleworking , Physical Distancing , Masks
20.
Article in Chinese | WPRIM | ID: wpr-908181

ABSTRACT

Objective:To develop the discrimination experience questionnaire for HIV/acquired immunodeficiency syndrome(AIDS) patients and test the reliability and validity of the questionnaire.Methods:Based on the literature review and semi-structured interviews to clarify the operational definition of discrimination for HIV/AIDS and develop the item pool. The questionnaire was developed though 2 rounds Delphi consultation and a pilot test. A total of 410 HIV/AIDS patients in Shanghai Public Health Clinical Center of Fudan University from June to December 2020 were selected to investigate the questionnaire, item analysis was used to screen items. SPSS 22.0 software was used for reliability test and exploratory factor analysis, the AMOS 21.0 software was used for confirmatory factor analysis to test the reliability and validity of the questionnaire.Results:The questionnaire consisted 2 dimensions(external discrimination and internal discrimination) and 10 items. Exploratory factor analysis showed that two common factors were extracted from the frequency of discrimination and the degree of negative psychological impact of discrimination experience on patients, and the cumulative variance contribution rates were 48.367% and 55.403%, respectively. The confirmatory factor analysis on the frequency of discrimination showed that Chi square degree of freedom ratio ( χ2/ df) was 2.831, P<0.05, root mean square of approximation error (RMSEA) was 0.093, goodness of fit index (GFI) was 0.928, comparative fit index (CFI) was 0.925, incremental fit index (IFI) was 0.926; the confirmatory factor analysis on the negative psychological impact of discrimination experience on patients showed that χ2/ df was 1.740, P<0.05; RMSEA was 0.076, GFI was 0.925, CFI was 0.936, IFI was 0.938. The content validity of the questionnaire was 0.9. The Cronbach α coefficientof questionnaire was 0.811, and the test-retest coefficient was 0.862 ( P<0.01). Conclusions:The discrimination experience questionnaire for HIV/AIDS patients has good reliability and validity, and it can be used to measure the discrimination for HIV/AIDS patients.

SELECTION OF CITATIONS
SEARCH DETAIL