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1.
Article in Chinese | WPRIM | ID: wpr-879112

ABSTRACT

Myrtus communis is a traditional medicinal aromatic plant in the Mediterranean. At present, the plant has been introduced and cultivated in the southern part of China, and it is mostly used for ornamental or cosmetic purposes. Based on literature analysis and the theory of Chinese medicine, we discussed the medicinal parts and properties of M. communis in this paper to provide a theoretical basis for exploring the medicinal value of M. communis and its compatibility with traditional Chinese medicines. Literatures were searched from Web of Science(core collection), PubMed, CNKI, VIP and Wanfang by using the set conditions as key words. Then the obtained literatures were screened and classified. Finally, a total of 376 articles were included, consisting of 44 reviews, 54 germplasm resources, 78 chemical researches, 48 studies on application, extraction, or quality, 18 human trials, 132 pharmacological studies, and 2 safety studies. Based on literature analysis and theories of Chinese medicine, the leaves of M. communis were finally selected as the medicinal part of Chinese medicine, and the traditional Chinese medicine properties of M. communis leaves were deduced as pungent, bitter, and cool. The channel tropisms of M. communis leaves included lung, liver, and large intestine, with functions of detoxifying, resolving a mass, and insecticide. It was used for mouth sores, vaginal itching, hemorrhoids and warts, etc.; appropriate amount shall be applied for external use, and the decoction form shall be used for washing the affected parts; 3-12 g equivalent product shall be used in decoction, and this herb shall be put into the decoction in a later stage. The clarification of the medicinal parts of M. communis, and the determination of the Chinese medicine properties of M. communis leaves would lay a theoretical foundation for its compatibility and application with Chinese medicines, and can do more contribution to the medical and healthcare industry in our country.


Subject(s)
China , Drugs, Chinese Herbal , Humans , Medicine, Chinese Traditional , Myrtus , Plant Leaves , Plants, Medicinal
2.
Article | IMSEAR | ID: sea-187739

ABSTRACT

Aims: Myrtus communis L. (Myrtle) is a plant widely used in traditional medicine in the Mediterranean Sea. The aim of this study was to determine the phenolic content of Myrtus communis L. leaves and to investigate the antioxydant activity of the methanol extract and its fractions. Methodology: Myrtus communis L. leaves were extracted using organic solvents with different polarities to get the following fractions: Methanol extract (ME), chloroform extract (CE), ethyl acetate extract (EE) and aqueous extract (AqE). Total polyphenol, flavonoid and tannins contents were evaluated for all extracts. The antioxidant capacity of different extracts was assessed using nine in vitro tests. Results: The results show that ME had the highest total phenolic content (149.25±3.11 mg GAE/g of dry extract), the  aqueous extract had the highest tannins content (83.35±0.36 mg TAE/ g of dry extract), whereas, EE had the highest total flavonoid content (38.4±0.9 mg QE/ g of dry extract).The EE exhibited an interesting antioxidant activity using ABTS radical scavenging assay (IC50=0.0015 mg/ml) and the DPPH test (IC50=0.004 mg/ml), while EA showed an important activity in the hydroxyl radical scavenging test (IC50=0.08 mg/ml), H2O2, (IC50=0.015 mg/ml), iron chelating (IC50=0.5 mg/ml) and reducing power (EC50=0.03 mg/ml). The greatest activity in inhibiting the oxidation of β-carotene/ linoleic acid was induced by CE and EE extracts (93.95%, and 90.29%, respectively). All extracts showed a very strong antiperoxidant effect against FTC and MDA tests. Conclusion: Myrtus communis L. leaves extracts have an important antioxidant activity which is most likely due to their polyphenolic content.

3.
Article in English | WPRIM | ID: wpr-819415

ABSTRACT

OBJECTIVE@#To evaluate the possible involvement of programmed cell death strategy in hydatid cyst protoscolices following treatment with Myrtus communis (M. communis) as an herbal medicine.@*METHODS@#Protoscolices were aseptically collected from sheep liver hydatid cysts. Evaluating the effect of M. communis extract on programmed cell death and increased activity of caspases 3, 8, and 9 in hydatid cyst protoscolices was conducted by treating the protoscolices with different concentration (5, 50, and 100 mg/mL) of M. communis extract at 37 °C and 5% CO for 4 h by using the Bradford test and ELISA commercial kits.@*RESULTS@#The extract of M. communis at all concentrations led to initiation of programmed cell death in protoscolices and this effect, was only significant at 50 and 100 mg/mL concentrations, compared to the negative control (P < 0.05). Also, the activity of caspases 3, 8, and 9 in hydatid cyst protoscolices, was shown that the extract at all 3 concentrations could only increase the activity of caspases 3 and 9. Moreover, a significant increase in the activity of caspase 3 was only observed at concentrations 50 and 100 mg/mL by 37.00% and 66.19% while a significant increase in the activity of caspase 9 at the same concentrations was observed by 20.89% and 63.67%, respectively (P < 0.05).@*CONCLUSIONS@#The extract of M. communis at different concentrations could increase the activity of caspases 3 and 9 and caused programmed cell death in hydatid cyst protoscolices however, this effect was significant at high concentrations of the extract.

4.
Article in English | WPRIM | ID: wpr-343224

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the antibacterial activity of the essential oil of Myrtus communis (M. communis) L. against Erysipelothrix rhusiopathiae (E. rhusiopathiae) in vitro.</p><p><b>METHODS</b>Wild populations of M. communis collected from Khuzestan and Lorestan provinces, Southwest Iran, were examined for antibacterial activity and chemical variability in leaves. The in vitro antibacterial activity against E. rhusiopathiae was performed by agar disc diffusion and micro-dilution assays.</p><p><b>RESULTS</b>The essential oils of M. communis have strong antibacterial against E. rhusiopathiae in both assays. The results showed that the major components of the oil were α-pinene (22.3%-55.2%), 1,8-cineole (8.7%-43.8%) and linalool (6.4%-14.5%). The inhibition zones and MIC values for bacteria which were sensitive to the essential oils of M. communis were in the range of 14.7-27.0 mm and 0.031-0.25 mg/mL, respectively.</p><p><b>CONCLUSIONS</b>This study demonstrates that products with valuable antibacterial activity can be produced from leaves of M. communis against E. rhusiopathiae.</p>

5.
Article in Chinese | WPRIM | ID: wpr-672795

ABSTRACT

Objective: To evaluate the antibacterial activity of the essential oil of Myrtus communis (M.communis Methods: Wild populations of M. communis collected from Khuzestan and Lorestan provinces, Southwest Iran, were examined for antibacterial activity and chemical variability in leaves. Thein vitro antibacterial activity against E. rhusiopathiae was performed by agar disc diffusion and micro-dilution assays.Results:) L. against Erysipelothrix rhusiopathiae (E. rhusiopathiae) in vitro. in both assays. The results showed that the major components of the oil were α-pinene (22.3%-55.2%), 1,8-cineole (8.7%-43.8%) and linalool (6.4%-14.5%). The inhibition zones and MIC values for bacteria which were sensitive to the essential oils of M. communis were in the range of 14.7-27.0 mm and 0.031-0.25 mg/mL, respectively.Conclusions:This study demonstrates that products with valuable antibacterial activity can be The essential oils of M. communis have strong antibacterial against E. rhusiopathiae produced from leaves of M. communis against E. rhusiopathiae.

6.
Article in English | WPRIM | ID: wpr-626153

ABSTRACT

Aims: Pseudomonas aeruginosa is a drug resistance opportunistic bacterium. Biofilm formation is key factor for survival of P. aeruginosa in various environments. Polysaccharides may be involved in biofilm formation. The purpose of this study was to evaluate antimicrobial and anti-biofilm activities of seven plant extracts with known alpha-glucosidase inhibitory activities on different strains of P. aeruginosa. Methodology and results: Plants were extracted with methanol by the maceration method. Antimicrobial activities were determined by agar dilution and by growth yield as measured by OD560nm of the Luria Bertani broth (LB) culture with or without extracts. In agar dilution method, extracts of Quercus infectoria inhibited the growth of all, while Myrtus communis extract inhibited the growth of 3 out of 8 bacterial strains with minimum inhibitory concentration (MIC) of 1000 μg/mL. All extracts significantly (p≤0.003) reduced growth rate of the bacteria in comparison with the control without extracts in LB broth at sub-MIC concentrations (500 μg/mL). All plant extracts significantly (p≤0.003) reduced biofilm formation compared to the controls. Glycyrrhiza glabra and Q. infectoria had the highest anti-biofilm activities. No correlation between the alpha-glucosidase inhibitory activity with growth or the intensity of biofilm formation was found. Conclusion, significance and impact of study: Extracts of Q. infectoria and M. communis had the most antimicrobial, while Q. infectoria and G. glabra had the highest anti-biofilm activities. All plant extracts had anti-biofilm activities with marginal effect on growth, suggesting that the mechanisms of these activities are unrelated to static or cidal effects. Further work to understand the relation between antimicrobial and biofilm formation is needed for development of new means to fight the infectious caused by this bacterium in future.

7.
Braz. j. pharm. sci ; 48(3): 547-555, July-Sept. 2012. ilus, graf
Article in English | LILACS | ID: lil-653469

ABSTRACT

A new trend in cosmetic formulations is the use of biotechnological raw materials as the polysaccharides from Klebsiella pneumoniae, which are supposed to enhance cell renewal, improve skin hydration and micro-relief. Botanical extracts of Myrtus communis leaves contain different sugars, which may provide the same benefits. Thus, the objective of this study was to evaluate through objective and subjective analysis the immediate and long-term effects of cosmetic formulations containing polysaccharides biotechnologically-originated and / or the ones contained in Myrtus communis extracts. Three polysaccharide-based and placebo formulations were applied on the forearm skin of 40 volunteers. Skin hydration, transepidermal water loss (TEWL), viscoelasticity and skin micro-relief measurements were made before and 2 hours after a single application and after 15 and 30 day-periods of daily applications. Answers to a questionnaire about perceptions of formulation cosmetic features constituted the subjective analysis. All polysaccharide-based formulations enhanced skin hydration. Formulations with isolated or combined active substances improved skin barrier function as compared to placebo, in the short and long term studies. Formulations containing Myrtus communis extracts had the highest acceptance. Results suggest that daily use of formulations containing these substances is important for protection of the skin barrier function.


Uma nova tendência em formulações cosméticas é a utilização de matérias-primas biotecnológicas como os polissacarídeos de Klebsiella pneumoniae, que pode aumentar a renovação celular e melhor a hidratação e micro-relevo da pele. Por outro lado, o extrato vegetal de Myrtus communis contém diferentes polissacarídeos, que também podem proporcionar benefícios à pele. Assim, o objetivo do estudo foi a avaliação dos efeitos imediatos e em longo prazo, de formulações cosméticas contendo polissacarídeos obtidos por processo biotecnológico e/ou de extrato de M. communis por meio de análises objetivas e subjetivas. Três formulações contendo os polissacarídeos e um placebo foram aplicadas na pele dos antebraços de 40 voluntários. As medidas foram realizadas antes e após 2 horas da aplicação das formulações e após 15 e 30 dias de aplicações diárias em termos de hidratação da pele, perda transepidérmica de água (TEWL), viscoelasticidade e micro-relevo da pele. Para a análise subjetiva, os voluntários responderam um questionário a fim de obter-se informações sobre a percepção relativa à qualidade de cosméticos. Todas as formulações provocaram aumento da hidratação cutânea. As formulações que continham os polissacarídeos melhoraram a função barreira da pele, em curto e em longo prazo. A formulação contendo extrato de M. communis apresentou maior aceitação. Os resultados sugerem que o uso diário dos polissacarídeos avaliados é importante na proteção da função barreira da pele.


Subject(s)
Humans , Polysaccharides/analysis , Skin , Additives in Cosmetics , Biotechnology/instrumentation , Fluid Therapy/classification , Klebsiella pneumoniae/classification , Myrtus communis/analysis
8.
Rev. bras. farmacogn ; 18(2): 241-244, abr.- jun. 2008. tab
Article in Portuguese | LILACS-Express | LILACS | ID: lil-488662

ABSTRACT

O óleo essencial e o extrato etanólico obtidos a partir de folhas de Myrtus communis foram avaliados quanto 'a atividade inibitória frente a vários microrganismos. Os halos de inibição de crescimento foram avaliados através das técnicas de "template" e difusão em disco para as linhagens de Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Bacillus subtilis e Serratia marcescens. Os resultados obtidos evidenciaram que o óleo de M. communis apresentou atividade antibacteriana superior ao extrato etanólico frente a todas as bactérias. A atividade demonstrada tanto para o óleo como para o extrato etanólico frente a algumas linhagens, foi melhor evidenciada pela técnica "template". E. coli foi resistente ao óleo e extrato etanólico testados.


We have studied the crude essential oil and crude ethanol extract from Myrtus communis leaves for possible antimicrobial activity against pathogenic bacteria. The halos of growth inhibition had been evaluated through the techniques of "template" and disk diffusion assays to the strains Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Bacillus subtilis and Serratia marcescens. The results demonstrated that M. communis oil presented superior antibacterial activity to all strains. The template assay was the best method to determine the antibacterial activity exhibited by the oil and extract to the strains. E. coli was resistant to the oil and ethanol extract tested.

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