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1.
Braz. j. biol ; 83: e251198, 2023. tab, graf
Article in English | MEDLINE, LILACS, VETINDEX | ID: biblio-1339350

ABSTRACT

Abstract The present study was designed to investigate the effects of Gundelia tournefortii L. plant extract on different tissues in terms of DNA damage, biochemical and antioxidant parameter values in rats with high-calorie diets. With this aim, Wistar albino male rats were divided into 4 groups containing 6 rats each and the study was completed over 12 weeks duration. At the end of the implementation process over the 12 weeks, rats were sacrificed and blood and tissue samples were obtained. Analyses were performed on blood and tissue samples. According to results for DNA damage (8-OHdG), in brain tissue the OG2 group was significantly reduced compared to the NC group. For MDA results in liver tissue, OG1 and OG2 groups were determined to increase by a significant degree compared to the control group, while the OG2 group was also increased significantly compared to the obese group. In terms of the other parameters, comparison between the groups linked to consumption of a high calorie diet (HCD) and administration of Gundelia tournefortii L. in terms of antioxidant activities and serum samples obtained statistically significant results. Gundelia tournefortii L. plant extracts had effects that may be counted as positive on antioxidant parameter activity and were especially identified to improve DNA damage and MDA levels in brain tissues. Additionally, consumption of Gundelia tournefortii L. plant extract in the diet may have antiobesity effects; thus, it should be evaluated for use as an effective weight-loss method and as a new therapeutic agent targeting obesity.


Resumo O presente estudo foi desenhado para investigar os efeitos do extrato da planta Gundelia tournefortii L. em diferentes tecidos em termos de danos ao DNA, valores de parâmetros bioquímicos e antioxidantes em ratos com dietas hipercalóricas. Com esse objetivo, ratos Wistar albinos machos foram divididos em 4 grupos contendo 6 ratos cada e o estudo foi concluído ao longo de 12 semanas de duração. No final desse processo de implementação, os ratos foram sacrificados e amostras de sangue e tecido foram obtidas. As análises foram realizadas em amostras de sangue e tecido. De acordo com os resultados para danos ao DNA (8-OHdG), no tecido cerebral o grupo OG2 foi significativamente reduzido em comparação com o grupo NC. Para os resultados de MDA no tecido hepático, os grupos OG1 e OG2 aumentaram significativamente em comparação ao grupo controle, enquanto o grupo OG2 também aumentou significativamente em comparação ao grupo obeso. Quanto aos demais parâmetros, a comparação entre os grupos ligados ao consumo de dieta hipercalórica (DC) e à administração de Gundelia tournefortii L. em termos de atividades antioxidantes e amostras de soro obteve resultados estatisticamente significativos. Os extratos de plantas de Gundelia tournefortii L. tiveram efeitos que podem ser considerados positivos na atividade dos parâmetros antioxidantes e foram especialmente identificados para melhorar os danos ao DNA e os níveis de MDA nos tecidos cerebrais. Além disso, o consumo de extrato vegetal de Gundelia tournefortii L. na dieta pode ter efeitos antiobesidade; portanto, deve ser avaliado para uso como um método eficaz de perda de peso e como um novo agente terapêutico voltado para a obesidade.


Subject(s)
Animals , Rats , Asteraceae , Antioxidants , DNA Damage , Plant Extracts/pharmacology , Rats, Wistar , Obesity/drug therapy
2.
Rev. bras. cir. plást ; 37(1): 53-59, jan.mar.2022. ilus
Article in English, Portuguese | LILACS-Express | LILACS | ID: biblio-1368212

ABSTRACT

Introdução: A obesidade é um dos principais problemas de saúde enfrentados pela população e sua incidência cresce gradativamente nas últimas décadas. Em meio à epidemia global de obesidade, os procedimentos bariátricos aumentaram expressivamente e, apesar do crescente número dos procedimentos pós-bariátricos, esses não se equivalem ao número de cirurgias bariátricas. Métodos: Foram coletados dados do registro de saúde pública (DATASUS) entre 2008 e 2019 para análise dos parâmetros selecionados, com avaliação das principais técnicas de dermolipectomia pós-bariátrica, sua distribuição em território nacional, seu tempo de internação, sua mortalidade, os custos para o Sistema Público, a comparação entre as dermolipectomias pós-bariátricas e a distribuição dos procedimentos bariátricos no território nacional. Além disso, comparou-se as dermolipectomias e a distribuição de cirurgiões plásticos no Brasil. Resultados: Um aumento de 164% foi evidenciado no número de dermolipectomias pós-bariátricas durante o período estudado. A dermolipectomia abdominal pós-bariátrica foi o procedimento mais realizado, sendo responsável por 65% dos procedimentos, seguido da dermolipectomia braquial (14,8%), crural (14,7%) e circunferencial (4,7%). Observou-se uma desigualdade na distribuição dos procedimentos pós-bariátricos entre as macrorregiões brasileiras, sendo a Região Sudeste com o maior número percentual (49,8%) de dermolipectomias. Conclusões: Apesar do aumento progressivo do número de dermolipectomias pós-bariátricas, elas não acompanharam o número de procedimentos bariátricos em território nacional. Por isso, há necessidade de um crescimento paralelo entre ambas, para que haja uma complementação no tratamento desses pacientes. Sendo assim, poderá existir melhora na distribuição das dermolipectomias no território nacional, fazendo com que mais pacientes possam ser beneficiados.


Introduction: Obesity is one of the main health problems faced by the population, and its incidence has gradually increased in recent decades. Amid the global obesity epidemic, bariatric procedures have increased significantly and, despite the growing number of post-bariatric procedures, these are not equivalent to the number of bariatric surgeries. Methods: Data were collected from the public health registry (DATASUS) between 2008 and 2019 to analyze the selected parameters, with an assessment of the main post-bariatric dermolipectomy techniques, their distribution in the national territory, their length of stay, their mortality, costs for the Public System, the comparison between post-bariatric dermolipectomies and the distribution of bariatric procedures in the national territory. Furthermore, dermolipectomies and the distribution of plastic surgeons in Brazil were compared. Results: An increase of 164% was evidenced in the number of postbariatric dermolipectomies during the studied period. Post-bariatric abdominal dermolipectomy was the most performed procedure, accounting for 65% of the procedures, followed by brachial (14.8%), crural (14.7%) and circumferential (4.7%) dermolipectomy. There was an inequality in the distribution of post-bariatric procedures among Brazilian macro-regions, with the Southeast Region having the highest percentage (49.8%) of dermolipectomies. Conclusions: Despite the progressive increase in post-bariatric dermolipectomies, they did not follow the number of bariatric procedures in the national territory. Therefore, there is a need for a parallel growth between both so that there is complementation in treating these patients. Then, there might be an improvement in the distribution of dermolipectomies in the national territory, allowing more patients to benefit.

3.
Arch. latinoam. nutr ; 72(1): 23-30, mar. 2022. tab, graf
Article in Spanish | LILACS, LIVECS | ID: biblio-1368353

ABSTRACT

La obesidad se define por un exceso de masa grasa, sin embargo, hay otros indicadores antropométricos que pueden ser útiles para el diagnóstico de sobrepeso u obesidad; Objetivo. Determinar la exactitud diagnóstica del índice de masa corporal (IMC), circunferencia de la cintura (CC) e índice de forma corporal (ABSI) para el diagnóstico de sobrepeso u obesidad en una población adulta del Ecuador. Materiales y métodos. Se desarrolló un estudio observacional de corte transversal en el que participaron 253 sujetos con edades entre 20 y 60 años. Se midió peso, estatura, circunferencia de la cintura y porcentaje de grasa corporal (PGC). Se correlacionó el PGC con IMC, CC y ABSI y se estableció la sensibilidad y especificidad de estos indicadores para el diagnóstico de sobrepeso u obesidad con curvas ROC. Resultados. El PGC fue menor en hombres que en mujeres (30,9 vs 41,87), ABSI y CC fue mayor en hombres que en mujeres (0,079 vs 0,075) y (99,76 vs 91,25) respectivamente. Se encontró una correlación positiva fuerte (≥0,75) entre el PGC e IMC y CC. En la curva ROC, el área bajo la curva más alta se observa para el IMC (0,949), mientras que el área más baja se observa para ABSI (0,395). Conclusión. El IMC es el indicador con mayor precisión diagnóstica de sobrepeso u obesidad. ABSI no sería un indicador útil en el diagnóstico de sobrepeso u obesidad(AU)


Obesity is defined by an excess of fat mass, however, there are other anthropometric indicators that can be useful for the diagnosis of overweight or obesity; Objetive. To determine the diagnostic accuracy of the body mass index (BMI), waist circumference (WC) and body shape index (ABSI) for the diagnosis of overweight or obesity in an adult population of Ecuador. Materials and methods. An observational cross-sectional study was carried out in which 253 subjects aged between 20 and 60 years participated. Weight, height, waist circumference and percentage body fat (PBF) were measured. The PBF was correlated with BMI, WC and ABSI and the sensitivity and specificity of these indicators were established for the diagnosis of overweight or obesity with ROC curves. Results. The PBF was lower in men than in women (30.09 vs 41.87), ABSI and CC were higher in men than in women (0.079 vs 0.075) and (99.76 vs 91.25) respectively. A strong positive correlation (≥0.75) was found between % body fat and BMI and WC. On the ROC curve, the area under the highest curve is observed for BMI (0.949), while the lowest area is observed for ABSI (0.395). Conclusion. The BMI is the indicator with the highest diagnostic precision of overweight or obesity. ABSI would not be a useful indicator in the diagnosis of overweight or obesity(AU)


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Body Mass Index , Adipose Tissue , Overweight , Body Fat Distribution , Obesity , Anthropometry , Cross-Sectional Studies , Diagnosis , Ecuador , Waist Circumference
4.
Saúde debate ; 46(132): 175-187, jan.-mar. 2022. tab
Article in Portuguese | LILACS-Express | LILACS | ID: biblio-1361148

ABSTRACT

RESUMO O objetivo do artigo é analisar as características dos processos de trabalho na Estratégia Saúde da Família direcionados às pessoas com sobrepeso e obesidade no município de São Paulo. Ancorado no referencial teórico da saúde coletiva sobre processo de trabalho, foi desenvolvido um estudo exploratório com abordagem qualitativa. Foram realizadas onze entrevistas com profissionais de uma unidade básica de saúde, na zona leste da cidade de São Paulo, entre os meses de julho e agosto de 2019. A partir da análise temática, o artigo apresenta os resultados e a discussão em três categorias analíticas: objeto de trabalho, instrumentos de trabalho e organização do trabalho. O cuidado às pessoas com sobrepeso e obesidade é mediado pelo baixo investimento em qualificação dos profissionais de saúde sobre o tema, pela falta de materiais técnicos de suporte ao trabalho e pelo modelo de gestão pautado pela produtividade e cobrança de resultados quantitativos. Conclui-se que os profissionais de saúde apresentam pouco domínio sobre seu processo de trabalho, cuja finalidade acaba sendo a mudança de comportamento e a perda de peso corporal, em vez de considerar as necessidades de saúde dos usuários e profissionais, produzindo, por vezes, insatisfação e desgaste com o trabalho.


ABSTRACT The goal of the article is to analyze the characteristics of the work processes in the Family Health Strategy directed to people with overweight and obesity in the city of São Paulo. Based on the theoretical framework of collective health about work processes, an exploratory study with a qualitative approach was developed. Eleven interviews were conducted with professionals from a basic health unit, in the east of the city of São Paulo, between July and August 2019. Starting with the thematic analysis, the article presents the results and discussion in three analytical categories: work object, work instruments and work organization. The care for people with overweight and obesity is mediated by the low investment in training health professionals on the subject, the lack of technical materials to support the work and the management model based on productivity and demand for quantitative results. It is concluded that health professionals have little control over their work process, whose purpose ends up being the change of behavior and the loss of body weight, instead of considering the health needs of users and professionals, sometimes producing dissatisfaction and weariness with work.

5.
Rev Bras Hipertens ; 29(1): 14-18, 20220310.
Article in Portuguese | LILACS-Express | LILACS | ID: biblio-1367456

ABSTRACT

Caso clínico de uma paciente do sexo feminino, encaminhada a nossa Instituição aos sete anos de idade por provável Hipertensão Arterial Sistêmica. A paciente apresentava obesidade grave desde os quatro anos e há alguns meses foram detectadas medidas de pressão arterial elevadas em várias consultas médicas. Tem antecedentes de rematuridade, sedentarismo e dieta inadequada, além de história familiar também de obesidade e hipertensão arterial. Discutimos as condutas quanto a investigação da etiologia, da presença de lesões de órgãos alvo e do tratamento. Na evolução, houve controle adequado da pressão arterial após início de inibidores da enzima de conversão da angiotensina, mas grande dificuldade na redução do peso. Ao longo do seguimento, mesmo sob orientações nutricionais e reforço quanto a modificações do estilo de vida, a paciente apresentou ganho ponderal de 25 quilos. Relatamos este caso atendendo a necessidade de discussão do tema frente ao aumento significativo da prevalência de HAS em crianças e adolescente. Existem aspectos multifatoriais para o desenvolvimento da hipertensão arterial na infância, em grande parte associada a um estilo de vida inadequado. As dificuldades relacionadas ao seu manejo a presença de comorbidades, em especial da obesidade, ressaltam a necessidade de uma abordagem multiprofissional para que a evolução do quadro da paciente venha a ser o desejado


Clinical case of a female patient referred to our Institution at the age of seven years old with Systemic Arterial Hypertension. The patient had been severely obese since she was 4 years old and high blood pressure levels were detected in several medical consultations a few months ago. She has a history of prematurity, a sedentary lifestyle, and an inadequate diet, in addition to a family history of obesity and high blood pressure. We discussed the investigation of the etiology, the presence of target organ lesions, and the treatment of arterial blood pressure in youth. In the follow-up, there was adequate control of blood pressure after initiation of angiotensin-converting enzyme inhibitor, with great difficulty in weight reduction. Even under nutritional guidelines and reinforcement regarding lifestyle changes, the patient had a weight gain of 25 kilos. We report this case in view of the significant increase in the prevalence of Systemic Arterial Hypertension in children and adolescents. There are multifactorial aspects to the development of this scenario, largely associated with an inadequate lifestyle. The difficulties related to its management and the presence of comorbidities, especially obesity, highlight the need for a ultidisciplinary approach so that the evolution of the patient's condition becomes as desired

7.
Arch. endocrinol. metab. (Online) ; 66(1): 3-11, Jan.-Feb. 2022. tab, graf
Article in English | LILACS-Express | LILACS | ID: biblio-1364308

ABSTRACT

ABSTRACT Objective: Our aim was to analyze levels of proinflammatory biomarker interleukin-18 (IL-18) in healthy controls and patients with polycystic ovary syndrome (PCOS) focusing on its association with obesity, clinical, hormonal, and metabolic characteristics. Subjects and methods: Fifty-eight patients with PCOS were enrolled in the study fulfilling the Rotterdam criteria and were matched for age, body mass index (BMI), and ethnicity with 30 healthy controls. Detailed anthropometric measurements, clinical investigations, hormonal and biochemical tests were obtained between the 3rd and 5th day of a menstrual cycle. A subanalysis of the PCOS group was performed separating patients into several groups according to a waist-to-height ratio (WHtR), insulin resistance (IR), and free androgen index (FAI). Serum IL-18 levels were measured using the ELISA method. Results: Levels of IL-18 were similar between PCOS patients and controls. IL-18 was higher in overweight/obese women compared to normal-weight women when analyzing all participants together and separately PCOS or controls group (p < 0.001, p < 0.001, p = 0.01, respectively). Additionally, IL-18 levels were higher in high-WHtR and IR subgroups compared to low-WHtR (p < 0.001) and non-IR PCOS women (p < 0.001). PCOS women with high FAI had greater serum IL-18 levels than normal-FAI patients (p = 0.002). Levels of IL-18 correlated positively with most of the anthropometric and metabolic parameters. In multiple linear regression, age, waist circumference, and fasting insulin were independently related factors with IL-18. Conclusion: Elevated levels of IL-18 were related to several indices of general and visceral adiposity and insulin resistance in PCOS.

8.
J. pediatr. (Rio J.) ; 98(1): 84-91, Jan.-Feb. 2022. tab, graf
Article in English | LILACS-Express | LILACS | ID: biblio-1360548

ABSTRACT

Abstract Objective: To validate the Family Health Behavior Scale (FHBS) for Brazilian families. Methods: The sample included 272 children aged 5 to 12 years old. Caregivers and their healthy answered the FHBS and questions about physical activity. In addition, anthropometric measurements of the children's weight and height were performed, as well as the bioimpedance exam. The scale was translated and the following validities were assessed: content (qualitative analysis and content validity index), construct (factor analysis) and concurrent validity (difference between domains and the total score with the categories of BMI, fat percentage and physical activity). Reliability (Cronbach's alpha, ceiling-floor effect, two-half test, intraclass correlation and Bland - Altman) was also assessed. Results: FHBS instrument performed well with regard to the psychometric properties in the Brazilian population. The content validity index was 0.987. Fit indices of the factor analysis were considered satisfactory, according to Bartlett's sphericity test (χ 2 = 1927, df = 351; p < 0.001) and the Kaiser-Meyer-Olkin index (KMO = 0.789). Concurrent validity, the differences between the mean of the domains and the total score between the categories of BMI (p = 0.011), percentage of fat (0.004) and physical activity (p < 0.001) were all significant. The reliability results were Cronbach's alpha internal consistency = 0.83, adequate ceiling-floor effect, 0.8105 (0.09 SD) two-half test, 0.626 intraclass correlation (95% CI: 0.406 to 0.777) and Bland - Altman -0.840 (-22.76 to 21.07). Conclusion: The FHBS adapted for the Brazilian population showed evidence of adequate psychometric performance.

9.
J. pediatr. (Rio J.) ; 98(1): 104-110, Jan.-Feb. 2022. tab, graf
Article in English | LILACS-Express | LILACS | ID: biblio-1360562

ABSTRACT

Abstract Objective: To estimate the prevalence and factors associated with overweight/obesity development in adolescents with early diagnosed phenylketonuria treated exclusively by diet. Methodology: In this cross-sectional study anthropometric measurements, serum phenylalanine levels, and 10 metabolites associated with lipid and carbohydrate metabolism were analyzed in 101 adolescents aged 10-20 years. Adolescents were categorized into overweight/obesity and eutrophic/low body mass index groups. These patients were compared using Student's t-test, Pearson's chi-square test, Wald's chi-square test for multivariate analysis. Further, to verify whether the prevalence of overweight/obesity found in the study population was similar to that in the general population, the authors compared the nutritional status of 46 patients aged 13-17 years with that of healthy students of the same age from the National School Health Survey using the chi-square test for adherence. The significance threshold was p < 0.5. Results: The prevalence of overweight/obesity in adolescents was 27.7%. There was no difference in prevalence between sexes. Older age was a protective factor and Increased Homeostasis Model Assessment Insulin Resistance index and high phenylalanine and low-density lipoprotein cholesterol levels were predictive factors for overweight/obesity. The equality hypothesis was not rejected in the comparison of nutritional states of 46 patients aged 13-17 years and healthy students of the same age. Conclusion: The prevalence of overweight/obesity in phenylketonuria adolescents was similar to what is found in healthy adolescents.

10.
Int. j. cardiovasc. sci. (Impr.) ; 35(1): 68-79, Jan.-Feb. 2022. tab
Article in English | LILACS-Express | LILACS | ID: biblio-1356304

ABSTRACT

Abstract Background The long incubation periods of cardiovascular diseases offer opportunities for controlling risk factors. In addition, preventive interventions in childhood are more likely to succeed because lifestyle habits become ingrained as they are repeated. Objective To investigate the effects of recreational physical activities, in combination or not with a qualitative nutritional counseling, in cardiometabolic risk factors of students with dyslipidemia and abdominal obesity. Methods Students (8-14 years old) were randomly divided into three groups (n=23 each): i ) Control; ii ) PANC, students undergoing Physical Activity and Nutritional Counseling, and iii ) PA, students submitted to Physical Activity, only. Blood samples (12-h fasting) were collected for biochemical analysis and anthropometric markers were also assessed. Two-Way RM-ANOVA and Holm-Sidak's test, and Friedman ANOVA on Ranks and Dunn's test were applied. P ≤ 0.05 was considered significant. Effect sizes were evaluated by Hedges' g and Cliff's δ for normal and non-Gaussian data, respectively. Results Compared to the control group and to baseline values, both interventions caused significant average reductions in total cholesterol (11%; p <0.001), LDL-c (19%; p=0.002), and non-HDL-c (19%; p=0.003). Furthermore, students in the PANC group also experienced a significant decrease in body fat compared to baseline (p=0.005) and to control (5.2%; g=0.541). Conclusions The proposed strategies were effective to reduce cardiometabolic risk factors in children and adolescents. The low cost of these interventions allows the implementation of health care programs in schools to improve the students' quality of life.

11.
Int. j. cardiovasc. sci. (Impr.) ; 35(1): 39-45, Jan.-Feb. 2022. tab
Article in English | LILACS-Express | LILACS | ID: biblio-1356317

ABSTRACT

Abstract Background: Abdominal obesity has been associated with cardiovascular disease and may be modulated by dietary intake. The deep abdominal subcutaneous adipose tissue (dSAT) is a body fat compartment that can be estimated by using mathematical formulas. Objectives: To evaluate the association between dSAT estimated by the Deep-Abdominal-Adipose-Tissue (DAAT) index and dietary intake in patients with acute coronary syndrome (ACS). Methods: This is a cross-sectional study conducted with patients ≥ 18 years of age admitted to a tertiary hospital. Sociodemographic, clinical, and anthropometric (body weight [kg], height [m], waist, hip and neck circumferences [cm]) data were evaluated. A food frequency questionnaire was applied to identify each patient's nutrient intake. The DAAT index was calculated according to specific formulas for men and women. Possible association between food intake and the DAAT index was evaluated by multiple linear regression. The level of significance adopted was 0.05. Results: This study evaluated 138 patients, with a mean age of 61.2±10.8 years. Prevalence of obesity was 29.4% in men and 37.7% in women. Regarding waist circumference, 83% of the women showed values considered to be very high. The DAAT index was significantly higher in men when compared to woman (P < 0.0001) and proved to be positively correlated with proteins (r= 0.22, P= 0.01) and monounsaturated fatty acid (r= 0.18, P= 0.04) intake in the entire sample. After adjustment for sex, alcohol consumption, and levels of physical activity, the DAAT index was associated with the female sex (B= −129.84, P <0.001) and a sedentary lifestyle (B= 57.99, P <0.001). Conclusion: dSAT estimated by the DAAT index was not associated with dietary intake in patients with ACS.

14.
Säo Paulo med. j ; 140(2): 199-206, Jan.-Feb. 2022. tab, graf
Article in English | LILACS-Express | LILACS | ID: biblio-1366037

ABSTRACT

Abstract BACKGROUND: Gastrointestinal (GI) symptoms are frequent complaints from individuals with nonalcoholic fatty liver disease (NAFLD). Dyspepsia is a universal clinical symptom and is among the most common GI complaints observed in the general population, but its prevalence in the population with NAFLD has not been previously investigated. OBJECTIVE: To compare the prevalence of functional dyspepsia (FD) between patients with NAFLD and controls without liver disease. DESIGN AND SETTING: Cross-sectional study at the Outpatient Liver Clinic, University Hospital, Belo Horizonte, Brazil. METHODS: We included 96 NAFLD patients and 105 controls without liver disease. All participants were assessed for GI symptoms in accordance with the Rome III criteria. Evaluation methods included a questionnaire for FD (validated in Brazil), laboratory tests and upper GI endoscopy. RESULTS: Mean age and sex were similar between the groups. The NAFLD group presented higher frequency of proton-pump inhibitor usage (31.3% vs 4.8%; P < 0.001) and prevalence of FD (25.0% versus 12.4%; P = 0.021). The symptom frequencies were as follows: postprandial distress, 22.9% versus 11.4% (P = 0.030); postprandial fullness, 18.8% versus 10.5% (P = 0.095); early satiation, 8.3% versus 5.7% (P = 0.466); and epigastric pain or burning, 18.8% versus 5.7% (P = 0.004), in NAFLD patients and controls, respectively. Multivariate analysis demonstrated that female sex (odds ratio, OR 6.97; 95% confidence interval, CI: 1.51-32.12; P = 0.013) and NAFLD diagnosis (OR 2.45; 95% CI: 1.14-5.27; P = 0.021) were independently associated with FD occurrence. CONCLUSION: FD occurs more frequently in individuals with NAFLD than in controls without hepatic disease.

15.
Säo Paulo med. j ; 140(2): 171-181, Jan.-Feb. 2022. tab
Article in English | LILACS-Express | LILACS | ID: biblio-1366046

ABSTRACT

Abstract BACKGROUND: Sitting time, screen time and low physical activity (PA) levels have been associated with several diseases and all-cause mortality. PA is related to better sleep quality and absence of daytime sleepiness, along with lower risks of obstructive syndrome apnea (OSA). However, studies on the relationship between sitting time, screen time and OSA are scarce in the literature. OBJECTIVE: To analyze associations between PA levels, sitting time, screen time and OSA among adults with suspected sleep disorder. DESIGN AND SETTING: Cross-sectional study conducted at Hospital Israelita Albert Einstein. METHODS: Data were collected from 369 adults with suspected sleep disorders who visited the hospital's neurophysiology clinic between August 2015 and January 2017. RESULTS: Correlations between hypopnea and PA indicators were demonstrated for total sitting time (0.123; P = 0.019) and total screen time (0.108; P = 0.038). There was also a correlation between latency for rapid-eye-movement sleep (REM_LAT) and total sitting time (0.103; P = 0.047) and a negative correlation between mean oxyhemoglobin saturation (SaO_Avg) and total PA time (-0.103; P = 0.048). There were no associations between PA parameters and apnea-hypopnea index. After adjusting for confounding factors (body mass index, age and gender), sitting time and screen time were not associated with OSA. CONCLUSION: After adjusting for anthropometric and clinical factors, excessive sitting time or screen time was not associated with OSA in adults suspected of sleep disorders. Age, gender, hypertension, body mass index and waist circumference were associated with OSA.

16.
Rev. bras. ativ. fís. saúde ; 27: 1-11, fev. 2022.
Article in English | LILACS | ID: biblio-1358721

ABSTRACT

This study aims to describe the development and validation of a permanent health education work-shop protocol for professional qualification in promoting adequate and healthy eating and physical activity and bodily practices for professionals working in Primary Health Care. The protocol de-velopment was based on the following theoretical references: Brazilian Dietary Guidelines, Brazil-ian Physical Activity Guidelines, Interprofessional Collaborative Practice, and Critical-Reflective Methodology (MCR); and it was proposed with 6 modules, totaling 30 hours of qualification. The protocol was evaluated in two panels of experts for content validation, which assessed aspects of clar-ity, relevance, and representativeness. The Content Validity Index (CVI), considering adequate the activities that scored CVI>0.8; and the proportion of theoretical representativeness in each activity were calculated. All 32 activities in the protocol have been validated for clarity and relevance, and the representativeness obtained results consistent with the objectives of each module. The represent-ativeness of MCR in the protocol as a whole was of 86.25%. The workshop activities protocol was evaluated as adequate for the proposed objective, considering its theoretical framework and its target audience. This is the first validated permanent education workshop to work in combination the Bra-zilian Dietary Guidelines and the Brazilian Physical Activity Guidelines, and it can be applied to the qualification of professionals in Primary Health Care throughout Brazil


O objetivo deste trabalho é descrever o desenvolvimento e validação de conteúdo de um protocolo de oficina de educação permanente em saúde para a qualificação profissional em promoção da alimentação adequada e saudável e da atividade física e práticas corporais voltado aos profissionais atuantes na Atenção Primária à Saúde. O desenvolvimento do protocolo utilizou como referenciais teóricos o Guia Alimentar para a Popu-lação Brasileira, o Guia de Atividade Física para a População Brasileira, a Prática Colaborativa Interpro-fissional e a Metodologia Crítico-Reflexiva (MCR); e foi definido com seis módulos presenciais, totalizando 30 horas de qualificação. O protocolo foi avaliado nos aspectos de clareza, pertinência e representatividade, em dois painéis de juízes para validação de conteúdo. Foram calculados o Índice de Validade de Conteúdo (IVC), considerando adequadas as atividades que pontuaram IVC>0,8; e o percentual de representatividade dos referenciais teóricos em cada atividade. Todas as 32 atividades do protocolo foram validadas para clareza e pertinência; e a representatividade obteve resultados condizentes com os objetivos de cada módulo. A repre-sentatividade da MCR no protocolo como um todo foi de 86,25%. As atividades da oficina foram avaliadas como adequadas ao objetivo proposto, considerando seu referencial teórico e seu público-alvo. Esta é a pri-meira oficina de educação permanente em saúde validada a trabalhar em formação combinada com o Guia Alimentar e o Guia de Atividade Física para a População Brasileira, e pode ser aplicada para a qualificação de profissionais da Atenção Primária à Saúde em todo Brasil


Subject(s)
Primary Health Care , Exercise , Diet , Education, Continuing , Obesity
17.
Rev. Ciênc. Méd. Biol. (Impr.) ; 20(4): 586-593, fev 11, 2022. tab
Article in Portuguese | LILACS | ID: biblio-1359359

ABSTRACT

Introdução: objetivamos avaliar associação entre ingestão de bebida alcoólica e estado antropométrico em estudantes que frequentam Restaurante Universitário. Metodologia: estudo transversal com 155 universitários em que foi avaliado o consumo de bebida alcoólica, frequência do consumo, tempo de consumo, quantidade e hábitos adotados enquanto bebiam. As medidas antropométricas realizadas foram estatura, peso, circunferência da cintura, circunferência do quadril e quatro dobras cutâneas (tricipital, bicipital, subescapular e suprailíaca). Para análise, realizamos estatística descritiva, o teste de qui-quadrado de independência para as proporções entre os grupos e a diferença entre as médias das medidas antropométricas de acordo a quantidade de bebida alcoólica consumida foi avaliada pelo teste ANOVA. Foram considerados significantes valores de p<0,05. Resultados: dos universitários, 63,87% eram bebedores, 23,2% dos bebedores estavam com excesso de peso, 21,2% apresentaram circunferência da cintura com risco elevado e percentual de gordura em excesso em ambos os grupos (77,8% vs. 73,2). Identificamos diferença estatisticamente para a circunferência da cintura entre o tempo de consumo (p=0,003) e entre o percentual de gordura corporal de acordo com a quantidade de bebida alcoólica consumida (p=0,001). Conclusão: o estado antropométrico dos universitários que consumiam bebida alcoólica apresentou alta frequência de excesso de peso e risco de complicações metabólicas associadas à obesidade, mesmo que sem significações estatísticas para as associações testadas.


Introduction: we aimed to evaluate the association between alcohol intake and anthropometric status in students who attend the University Restaurant. Methodology: cross-sectional study with 155 university students in which the consumption of alcoholic beverages, frequency of consumption, consumption time, quantity and habits adopted while drinking were evaluated. The anthropometric measurements taken were height, weight, waist circumference, hip circumference and four skinfolds (triceps, biceps, subscapular and suprailiac). For analysis, we performed descriptive statistics, the chi-square test of independence for proportions between groups and the difference between the means of anthropometric measures according to the amount of alcoholic beverage consumed was evaluated by the ANOVA test. Significant values of p<0.05 were considered. Results: of the college students, 63.87% were drinkers, 23.2% of the drinkers were overweight, 21.2% high risk waist dissipation and fat percentage in both groups (77.8% vs. 73 ,two). We identified a statistically significant difference for waist circumference between consumption time (p = 0.003) and between body fat percentage according to the amount of alcoholic beverage consumed (p = 0.001). Conclusion: the anthropometric status of college students who drank alcoholic beverages presented a high frequency of weight and risk of metabolic complications associated with obesity, even if without statistical significance for the tested associations.


Subject(s)
Humans , Male , Female , Adult , Restaurants , Students , Body Mass Index , Obesity, Abdominal , Alcohol Drinking in College , Cross-Sectional Studies , Evaluation Studies as Topic
18.
Rev. Ciênc. Méd. Biol. (Impr.) ; 20(4): 594-600, fev 11, 2022. fig
Article in Portuguese | LILACS | ID: biblio-1359363

ABSTRACT

Introdução: distúrbios do sono são comuns na gravidez e decorrem de modificações anatômicas, fisiológicas e hormonais. A atenção primária à saúde encontra-se em posição singular no reconhecimento de tais desordens. Nesse contexto, esta pesquisa tem como objetivo avaliar a qualidade do sono de gestantes em uma Unidade Básica de Saúde e correlacioná-la com parâmetros analisados durante o acompanhamento pré-natal. Metodologia: trata-se de um estudo observacional, transversal e analítico, desenvolvido por meio de pesquisa de campo, com gestantes acompanhadas em uma Unidade Básica de Saúde. Os dados foram obtidos utilizando uma ficha de questionário que associava algumas variáveis com a qualidade do sono, mensurada pelo Índice de Qualidade do sono de Pittsburgh, em sua versão brasileira (PSQI-BR). Resultados e Discussão: foram entrevistadas 83 gestantes, com 76 preenchendo os critérios de inclusão. A maioria das pacientes possuía idade inferir a 26 anos (64,4%), era multípara (59,2%), com peso inadequado (72,4%), não tinha distúrbio hipertensivo na gestação (76,3%) e estava no primeiro trimestre (40,8%). Após a aplicação do teste qui-quadrado de Pearson e a razão de chances, verificou-se que as três últimas variáveis citadas tinham relação com a qualidade do sono, apresentando significância estatística (p<0,05). Além disso, 34,2% das gestantes tinha má qualidade do sono. Conclusão: a qualidade do sono deve ser avaliada durante o acompanhamento pré-natal, visto que seu comprometimento é frequente, sobretudo diante de certos fatores de risco, e pode resultar em desfechos maternos adversos. Assim, o reconhecimento precoce possibilita melhora do prognóstico gestacional.


Introduction: sleep disorders are common in pregnancy and result from anatomical, physiological and hormonal changes. Primary health care is in a unique position in recognizing such disorders. In this context, this research aims to assess the quality of sleep of pregnant women in a Basic Health Unit and associated it with parameters analyzed during prenatal care. Methodology: this is an observational, cross-sectional and analytical study, developed through field research, with pregnant women accompanied in a Basic Health Unit. The data were obtained using a questionnaire form that correlated some variables with the quality of sleep, measured by the Pittsburgh Sleep Quality Index, in its Brazilian version (PSQI-BR). Results and Discussion: 83 pregnant women were interviewed, with 76 fulfilling the inclusion criteria. Most patients were 26 years old (64.4%), multiparous (59.2%), with inadequate weight (72.4%), had no hypertensive disorder during pregnancy (76.3%) and were in the first quarter (40.8%). After applying Pearson's chi-square test and odds ratio, it was found that the last three variables mentioned were related to sleep quality, showing statistical significance (p <0.05). In addition, 34.2% of pregnant women had poor sleep quality. Conclusion: the quality of sleep should be assessed during prenatal care, as its impairment is frequent, especially in the face of certain risk factors, and can result in adverse maternal outcomes. Thus, early recognition makes it possible to improve gestational prognosis.


Subject(s)
Humans , Adult , Sleep , Pregnancy , Hypertension , Obesity , Analytical Methods , Demography , Observational Study
19.
Ciênc. Saúde Colet ; 27(1): 363-375, jan. 2022. tab, graf
Article in English, Portuguese | LILACS | ID: biblio-1356041

ABSTRACT

Resumo O objetivo deste estudo foi analisar a tendência temporal da prevalência de excesso de peso (EP) em crianças menores de cinco anos assistidas pelo Programa Bolsa Família (PBF) entre 2008 e 2018. O painel de dados foi baseado nos relatórios de estado nutricional do Sistema de Vigilância Alimentar e Nutricional (SISVAN) (n=30.574.118) e analisado por meio de modelos de regressão joinpoint específicos para idade (lactentes e pré-escolares) e macrorregião. Ainda, calculou-se a cobertura do SISVAN para o PBF e a representatividade nacional, segundo projeção censitária. Na década analisada, o EP em lactentes reduziu de 11,9% (11,8; 12,0 IC95%) para 8,5% (8,4; 8,6 IC95%) (-3,6%/ano [-5,1; -2,0 IC95%]); quanto aos pré-escolares, a prevalência EP aumentou em 3,1%/ano (2,0; 4,2 IC95%) até 2015, seguida por uma retração até 2018 (-6,4%/ano [-10,1; -2,6 IC95%]). Em ambos os grupos etários, a região Norte apresentou a menor prevalência em toda série histórica e a Nordeste o pior desempenho no controle do EP infantil. A cobertura do SISVAN no PBF foi elevada e a representatividade dos dados variou entre 13,9% (Sul) e 42,2% (Nordeste). Apesar da prevalência estar acima do esperado, após 2014, identificou-se redução linear no EP em lactentes e desaceleração na taxa de crescimento nos pré-escolares.


Abstract This study aimed to analyze the overweight (OW) prevalence trends from 2008 to 2018 among under-five-year-old children assisted by the conditional cash transfer program entitled Programa Bolsa Família (PBF). The panel was based on the Food and Nutritional Surveillance System (SISVAN) (n=30,574,118) nutritional status reports. Age- (infants and preschoolers) and region-specific joinpoint regression models were used to analyze OW's prevalence temporal changes. Besides, the coverage of SISVAN for PBF and national representativity were calculated according to census projection. In the decade analyzed, OW in infants decreased from 11.9% (11.8; 12.0 95%CI) to 8.5% (8.4; 8.6 95%CI) (-3.6%/year [-5.1; -2.0 95%CI]); for preschool children, the prevalence of OW increased by 3.1%/year (2.0; 4.2 95%CI) until 2015, followed by a decrease until 2018 (-6.4%/year [-10.1; -2.6 95%CI]). In both age groups, the North region had the lowest prevalence in all time-series, and the Northeast had the worst performance in managing childhood obesity. The SISVAN's coverage in the PBF was high, and the data representativity varied between 13.9% (South) and 42.2% (Northeast). Although the prevalence was higher than expected, after 2014, it was detected a linear reduction in OW in infants and a deceleration in the growth rate in preschoolers.


Subject(s)
Humans , Infant , Child, Preschool , Child , Overweight/epidemiology , Pediatric Obesity/epidemiology , Poverty , Nutritional Status , Prevalence
20.
Int. braz. j. urol ; 48(1): 122-130, Jan.-Feb. 2022. tab, graf
Article in English | LILACS-Express | LILACS | ID: biblio-1356274

ABSTRACT

ABSTRACT Purpose: To analyze the association between obesity and urinary incontinence rate in men submitted to robot-assisted radical prostatectomy (RARP) in a high-volume cancer center. Materials and Methods: We reported 1.077 men who underwent RARP as the primary treatment for localized prostate cancer from 2013 to 2017. Patients were classified as non-obese (normal BMI or overweight) or obese men (BMI ≥30kg/m2). They were grouped according to the age, PSA level, D'Amico risk group, Gleason score, ASA classification, pathological stage, prostate volume, salvage/adjuvant radiotherapy, perioperative complications, and follow-up time. Urinary continence was defined as the use of no pads. For the analysis of long-term urinary continence recovery, we conducted a 1:1 propensity-score matching to control confounders. Results: Among the obese patients, mean BMI was 32.8kg/m2, ranging 30 - 45.7kg/m2. Only 2% was morbidly obese. Obese presented more comorbidities and larger prostates. Median follow-up time was 15 months for the obese. Complications classified as Clavien ≥3 were reported in 5.6% of the obese and in 4.4% of the non-obese men (p=0.423). Median time for continence recovery was 4 months in both groups. In this analysis, HR was 0.989 for urinary continence recovery in obese (95%CI=0.789 - 1.240; p=0.927). Conclusions: Obese can safely undergo RARP with similar continence outcomes comparing to the non-obese men when performed by surgeons with a standardized operative technique. Future studies should perform a subgroup analysis regarding the association of obesity with other comorbidities, intending to optimize patient counseling.

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