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1.
Acta fisiatrica ; 29(3): 204-218, set. 2022.
Article in Portuguese | LILACS-Express | LILACS | ID: biblio-1391548

ABSTRACT

A lesão medular altera funções motoras e sensitivas, podendo causar limitações de atividades e restrição de participação. Nesse contexto, é frequente a presença de alterações da sexualidade, relacionadas a diminuição da função sexual, libido, baixa autoestima e aceitação social. Apesar disso, a sexualidade e seus desdobramentos têm sido pouca integrada no processo de reabilitação dessas pessoas. Objetivo: Compreender a sexualidade da pessoa com lesão medular, suas vivências e estratégias utilizadas, bem como a atuação de profissionais de saúde nessa área a partir da percepção de pessoas com lesão medular. Método: Estudo descritivo de análise qualitativa, que incluiu 12 pessoas com lesão medular, de idades entre 23 e 56 anos, usuários do Projeto Praia Para Todos, Rio de Janeiro. A coleta de dados foi realizada através de entrevista gravada por telefone. Os instrumentos utilizados foram Ficha de identificação sociodemográfica, roteiro de entrevista semiestruturado e Quociente Sexual. A inferência e interpretação dos dados foram realizados após transcrição das entrevistas na íntegra. Resultados: A lesão medular acarretou mudanças na vivência da sexualidade em aspectos físicos, psicossociais e ambientais. As principais estratégias utilizas foram mudança de hábitos, utilização de equipamentos, técnicas, medicamentos e busca por rede de suporte social. Embora o processo de reabilitação tenha se dado através de equipe multidisciplinar, foi identificado ausência de abordagem da sexualidade. Conclusão: Sugere-se mais estudos que visem identificar as limitações, barreiras e estratégias utilizadas por pessoas com lesão medular e outras deficiências, bem como o esclarecimento a profissionais de saúde sobre a importância da atuação nesse campo.


Spinal cord injury alters motor and sensory functions, which may cause activity limitations and participation restriction. In this context, the presence of changes in sexuality is frequent, related to decreased sexual function, libido, low self-esteem and social acceptance. Despite this, sexuality and its consequences have been poorly integrated in the rehabilitation process. Objective: Comprehend the spinal cord injured person's sexuality, their experiences and strategies used, as well as the action of healthcare professionals in this area. Method: Descriptive study of qualitative analysis, which included 12 people with spinal cord injury, aged between 23 and 56 years; they were users of the Praia Para Todos Project, Rio de Janeiro. Data were collected through recorded phone interviews. The instruments used were a sociodemographic identification form, a semi-structured interview script and the Sexual Quotient Questionnaire. The inference and interpretation of data were performed after transcribing the interviews in full. The inferring and interpretation data were performed after the transcription of the full interview. Results: Spinal cord injury caused changes in the experience of sexuality in physical, psychosocial and environmental aspects. The main strategies used were changing habits, using equipment, techniques, medications and seeking a social support network. Although the rehabilitation process happened through a multidisciplinary team, an absence of approach to sexuality was identified. Conclusion: Further studies are suggested that aim to identify limitations, barriers and application by people with spinal cord injury and other disabilities, as well as clarification to health professionals about the importance of working in this field.

2.
Rev. bras. ortop ; 57(4): 584-589, Jul.-Aug. 2022. tab, graf
Article in English | LILACS | ID: biblio-1394872

ABSTRACT

Abstract Objective To describe magnetic resonance imaging (MRI) characteristics of shoulders from patients with spinal cord injury (SCI) and to correlate these findings with age, duration of SCI and neurological level. Method The study sample included patients with thoracic SCI over 18 years of age, who were active wheelchair users and had undergone an MRI of the shoulder from January 2004 to December 2015. Results We studied 41 shoulders (37 patients), including 27 men (65.9%) and 14 women (34.1%). At the time of MRI, the mean age was 41.9 years and the mean duration of SCI was 9.4 years. The analysis of the relationship between the duration of trauma and severity of the rotator cuff lesion (RCL), as well as between age and the severity of the shoulder injury showed a statistically significant difference (p< 0.001), with a positive association in both cases. No statistically significant difference (p= 0.095) was observed between the neurological level of the SCI and RCL. Conclusion In this study, a progressive increase in the severity of the shoulder lesions can be noted with advancing age and a longer duration of SCI. However, level of the SCI does not seem to interfere with RCL. Level of Evidence Level IV, case series.


Resumo Objetivo Descrever as características de ressonância magnética (RM) dos ombros de pacientes com lesão medular (LM) e correlacionar esses achados com idade, duração da LM e nível neurológico. Método A amostra do presente estudo incluiu pacientes maiores de 18 anos com LM torácica, que eram cadeirantes ativos e haviam sido submetidos a uma ressonância magnética do ombro de janeiro de 2004 a dezembro de 2015. Resultados Foram estudados 41 ombros (37 pacientes), incluindo 27 de pacientes do sexo masculino (65,9%) e 14 de pacientes do sexo feminino (34,1%). Na época da ressonância magnética, a média de idade era de 41,9 anos e a duração média da LM era de 9,4 anos. A análise da relação entre a duração do trauma e a gravidade da lesão do manguito rotador (LMR), bem como entre a idade e a gravidade da lesão do ombro mostrou diferença estatisticamente significativa (p< 0,001), com associação positiva em ambos os casos. Não foi observada diferença estatisticamente significativa (p= 0,095) entre o nível neurológico da LM e da LMR. Conclusão Neste estudo, pode-se notar um aumento progressivo da gravidade das lesões do ombro com o avanço da idade e uma maior duração da LM. No entanto, o nível da LM não parece interferir com a LMR. Nível de Evidência Nível IV, série de casos.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Spinal Cord Injuries/diagnostic imaging , Wheelchairs , Magnetic Resonance Imaging , Retrospective Studies , Shoulder Injuries/diagnostic imaging
3.
Rev. bras. ortop ; 57(4): 697-701, Jul.-Aug. 2022. graf
Article in English | LILACS | ID: biblio-1394871

ABSTRACT

Abstract A 26-year-old previously healthy patient who, at the age of 18 years, began progressive loss of distal strength, rest tremor, and muscle atrophy in the left upper limb. Upon examination, the patient presented moderate distal atrophy, degree 4 in muscular strength, and minipolymioclonus. Electromyoneurography revealed (EMNG) chronic preganglionic bilateral involvement of bilateral C7/C8/T1, worse on the left, with signs of active C8/T1 denervation. A cervical spine magnetic resonance imaging (MRI) scan showed spondylodiscal degenerative changes with central protrusions in C4-C5, C6-C7, and right central in C5-C6, which touched the dural sac. The anteroposterior diameter of the medulla in neutral position, in the C5-C6 plane, was of 5.1 mm. There was a reduction of the spinal cord caliber to 4.0 mm after the dynamic maneuver of forced flexion of the spine, as well as signal increase in the anterior horns. The clinical findings and those of the complementary tests were compatible with Hirayama disease (HD), a rare benign motor neuron disease that affects cervical spinal segments and is most prevalent in men, with onset in the early 20s. Unilateral and slowly progressive weakness is typical, but self-limited. Sensory disturbances, and autonomic and upper motor neuron signals are rare. Management is usually conservative, with the use of a soft cervical collar. Although rare, HD should be considered in young patients with focal asymmetric atrophy in the upper limbs. The early diagnosis of HD depends on the degree of suspicion, as well as on the cooperation and communication among the various specialties involved in the investigation.


Resumo Paciente de 26 anos, previamente hígido, que, aos 18 anos, iniciou perda progressiva de força distal, tremor de repouso, e atrofia muscular no membro superior esquerdo. Ao exame, apresentou atrofia moderada, distal, força muscular de grau 4, e minipolimioclonus. A eletroneuromiografia (ENMG) revelou comprometimento pré-ganglionar crônico de C7/C8/T1 bilateral pior à esquerda, com sinais de desnervação ativa em C8/T1. A ressonância magnética (RM) de coluna cervical mostrou alterações degenerativas espondilodiscais com protrusões centrais em C4-C5, C6-C7, e central direita em C5-C6, que tocavam o saco dural. O diâmetro anteroposterior da medula na posição neutra, no plano de C5-C6, era de 5,1 mm. Houve redução do calibre da medula para 4,0 mm após a manobra dinâmica de flexão forçada da coluna, e aumento de sinal nos cornos anteriores. Os achados clínicos e os dos exames complementares eram compatíveis com doença de Hirayama (DH), uma doença benigna rara dos neurônios motores, que afeta os segmentos espinhais cervicais e é mais prevalente em homens e de início próximo aos 20 anos. É típica a fraqueza unilateral e lentamente progressiva, porém autolimitada. Perturbações sensoriais, sinais autonômicos e do neurônio motor superior são raras. O manejo geralmente é conservador, com uso de colar cervical macio. Apesar de rara, a DH deve ser considerada em pacientes jovens que apresentam atrofias assimétricas focais de membros superiores. O diagnóstico precoce de DH depende do grau de suspeição, e da cooperação e comunicação entre as diversas especialidades envolvidas na investigação.


Subject(s)
Humans , Adult , Spinal Cord/pathology , Magnetic Resonance Imaging , Muscular Atrophy/diagnostic imaging , Spinal Muscular Atrophies of Childhood/diagnostic imaging
4.
Rev. med. (Säo Paulo) ; 101(4): e-173259, jul.-ago. 2022.
Article in English, Portuguese | LILACS-Express | LILACS | ID: biblio-1392116

ABSTRACT

A reabilitação na esteira com suporte parcial de peso (ESPP) nos indivíduos lesados medulares pode reproduzir de modo passivo a marcha, proporcionando-lhes a descarga de peso em membros inferiores (MMII) e a manutenção da postura ortostática. O objetivo do estudo foi analisar se, durante a marcha passiva na ESPP, existe irradiação motora de MMII aos membros superiores. Foram selecionados três indivíduos do gênero masculino, com diagnóstico de Traumatismo Raquimedular baixo (T10 e L1), classificados como ASIA A com preservação parcial de raízes nervosas. Os indivíduos foram submetidos a uma avaliação passiva da marcha na ESSP, utilizando a avaliação eletromiográfica dos músculos: bíceps braquial (BB), reto femoral (RF) e gastrocnêmio lateral (GL) bilateralmente e a uma análise estatística, incluindo testes de Shapiro-Wilk e de Levene, One way ANOVA, post-hoc Tukey HSD. Na condição clínica de repouso, observou-se menor ativação dos músculos BB bilateralmente, quando comparado aos músculos RF e GL, fato justificado pelos comprometimentos secundários advindos da lesão dos indivíduos. As condições clínicas do ciclo da marcha (CM) repetiram-se três vezes; no CM1 observou-se uma maior ativação eletromiográfica do músculo GL direito e uma menor ativação do músculo BB direito, e estatisticamente, GL direito e BB esquerdo demonstraram maior atividade média (resultados estatisticamente significantes). No CM2 o mesmo padrão de ativação do CM1 foi observado, no entanto o músculo RF direito reduziu seu limiar de ativação. No CM3 os níveis de ativação das condições anteriores mantiveram-se, no entanto, o músculo RF esquerdo apresentou aumento nos limiares de ativação eletromiográfica, quando comparado aos demais músculos. Com base nestes resultados, o músculo BB apresentou variações quantitativas na ativação eletromiográfica, determinando a presença de irradiação motora de MMII para superiores durante o CM. Em uma análise qualitativa, foi observado que durante as fases de apoio da marcha houve "picos" de ativação deste músculo. [au]


Rehabilitation on the treadmill with partial body weight support (PBWS) in individuals with spinal cord injuries can passively reproduce gait, helping them with weight bearing on the lower limbs (LL) and orthostatic posture. The objective of the study was to assess motor irradiation from the lower limbs to the upper limbs during gait training with PBWS. The participants were three male individuals diagnosed with low spinal cord injury (T10 and L1), classified as ASIA A, with partial preservation of nerve roots. Subjects were submitted to gait training with PBWS and electromyographic assessment of the muscles Biceps brachii (BB), Rectus femoris (RF) and Lateral Gastrocnemius (LG) on both sides. Statistical analysis included Shapiro-Wilk and de Levene tests, One way ANOVA test and Tukey's HSD post-hoc test. In the resting state, there was less activity of BB muscles on both sides when compared to the RF and LG, which can be explained by the secondary impairments arising from the individuals' injury. The gait cycle (GC) was repeated three times; in GC1 there was greater electromyographic activity in the right LG muscle and lower activity of the right BB muscle and, statistically, right LG and left BB showed higher mean activity (statistically significant results). In GC2, the same pattern of activity of GC1 was observed, but the right RF muscle reduced its activation threshold. In GC3, the activity levels of the previous cycles were maintained, but the left RF muscle showed an increase in the thresholds of electromyographic activation when compared to the other muscles. Based on these results, the BB muscle presented quantitative variations in electromyographic activation, demonstrating the presence of motor irradiation from LL to upper limbs during the GC. The qualitative analysis showed "peaks" of activity in this muscle mainly during the support phases of the gait training. [au]

5.
Rev. Bras. Neurol. (Online) ; 58(1): 24-28, jan.-mar. 2022. tab
Article in Portuguese | LILACS-Express | LILACS | ID: biblio-1377971

ABSTRACT

Foram comparadas características clínicas e epidemiológicas de pacientes com tetraplegia traumática e Malformação de Chiari tipo I, atendidos em centro de neurorreabilitação através de estudo observacional analítico e retrospectivo, realizado por meio de análise de prontuário eletrônico. No grupo de pacientes com Malformação de Chiari tipo I predominaram mulheres, com marcha e que apresentavam transtornos de ansiedade e a presença de siringomielia. No grupo com tetraplegia traumática predominaram os homens, com locomoção em cadeira de rodas e maior presença de espasticidade e disfunções neurogênicas do intestino e do trato urinário inferior. Os pacientes com Malformação de Chiari tipo I representam um grupo com diferentes características clínicas e epidemiológicas em relação aos pacientes com sequelas de traumatismo raquimedular, tradicionalmente o principal grupo atendido dentro dos programas de neurorreabilitação. Desta forma, os pacientes com Malformação de Chiari tipo I necessitam de uma abordagem diferenciada que contemplem suas necessidades nos programas de neurorreabilitação.


Clinical and epidemiological characteristics of patients with traumatic tetraplegia and Chiari malformation type I treated at a neurorehabilitation center were compared through an analytical and retrospective observational study, carried out through electronic medical record analysis. In the group of patients with Chiari malformation type I predominated female gender, with gait, the presence of syringomyelia and anxiety disorders. In the group with traumatic tetraplegia predominated male gender, use of wheelchair and presence of spasticity and neurogenic dysfunctions of the bowel and lower urinary tract. Patients with Chiari malformation type I represent a group with different clinical and epidemiological characteristics in relation to patients with sequelae of spinal cord injury, traditionally the main group treated within neurorehabilitation. Thus, patients with Chiari malformation type I need a differentiated approach that addresses their needs in neurorehabilitation.

6.
Acta fisiátrica ; 29(2): 98-103, jun. 2022.
Article in Portuguese | LILACS-Express | LILACS | ID: biblio-1372978

ABSTRACT

Queda é definida como o deslocamento não intencional, com incapacidade de correção em tempo hábil do corpo a um nível inferior à posição inicial. Quedas, em hospitais, são mais frequentes em unidades com pacientes idosos, neurológicos e de reabilitação. Objetivo: Trata-se de um estudo descritivo de análise retrospectiva, com objetivo de caracterizar o perfil dos pacientes com lesão medular (LM) que apresentaram queda durante internação em um hospital de reabilitação e analisar a associação das características clínicas e das quedas dos pacientes com a presença ou não de dano após a queda. Método: Dados coletados de prontuários entre janeiro/2015 e dezembro/2017. A amostra compôs-se de pacientes adultos com LM. Excluídos prontuários cuja análise não permitiu o levantamento dos dados. A análise estatística utilizou medidas de tendência central e dispersão para as variáveis quantitativas e medidas de frequência para as categóricas. Utilizado teste Qui-quadrado de Pearson exato para avaliar a associação das variáveis e presença de dano após queda, com exceção da idade, analisada pelo teste Man-Whitney. Resultados: Analisados 173 prontuários. Observou- se maior frequência de quedas em homens com paraplegia, durante o dia, em atividades não supervisionadas e durante o uso de cadeira de rodas. Não houve associação entre as variáveis de caracterização da amostra e quedas com dano. Conclusão: As quedas acometeram principalmente indivíduos com lesões torácicas, usuários de cadeira de rodas, durante a locomoção, transferências e ao empiná-las. Ressalta-se a importância do treino de habilidades em cadeira de rodas para ampliar as habilidades no uso desse recurso.


Falls are defined as an unintentional body displacement towards a level below the initial position, with the inability to correct the body promptly. In hospitals, falls are more frequent among the elderly, those with neurological impairment, and patients under physical rehabilitation. Objectives: This is a descriptive retrospective study to characterize patients with spinal cord injury who underwent falls when admitted to a rehabilitation hospital and establish the association between clinical characteristics and the presence or absence of injuries due to the fall. Method: Data were collected from medical records between January 2015 and December 2017. The sample consisted of patients aged 18 years or above with spinal cord injury. Medical records whose data did not allow the study variables to be retrieved were excluded. The statistical analysis included data description followed by Pearson's exact chi-square test to establish the association between clinical and demographical variables and the presence of injuries due to the fall, except for age, which was analyzed with Mann-Whitney's test. Results: 173 medical records were included and analyzed. A higher frequency of falls was observed among men with paraplegia, during the day, during unsupervised activities, and while using a wheelchair. There was no association between the clinical or demographical variables and falls with injuries. Conclusion: Falls mainly affect individuals with thoracic injuries, wheelchair users during locomotion, transfers, and when they are lifting or tilting their wheelchairs. The findings reiterate the importance of training for wheelchair users to enhance their abilities.

7.
Rev. colomb. anestesiol ; 50(2): e302, Jan.-June 2022. tab, graf
Article in English | LILACS | ID: biblio-1376822

ABSTRACT

Abstract The use of advanced invasive techniques for the control of chronic pain in patients with multiple comorbidities is becoming increasingly common. Neuromodulation offers a new management alternative involving the infusion of one or more drugs into the epidural or intrathecal space through a fully implantable infusion pump. It also involves spinal stimulation, a minimally invasive technique in which electrodes are positioned in the epidural space and connected to a pulse generator that is implanted subcutaneously and generates pulses designed to suppress the noxious stimulus. This article will describe the anesthetic considerations in cases of implantable drug delivery systems, and spinal and peripheral nerve stimulation devices. Additionally, patients with electrical or drug neuromodulation devices may present to anesthetic practice for surgical indications unrelated to their chronic pain pathology. Hence the importance of being familiar with the basic components of these devices, how they work, what drugs they use and the potential associated complications in the perioperative context, in order to ensure proper management and patient safety.


Resumen Cada vez es más común el empleo de técnicas invasivas avanzadas para el control del dolor crónico en paciente con múltiples comorbilidades. La neuro-modulación ofrece una nueva alternativa de manejo, que involucra la infusión de uno o más medicamentos en el espacio epidural o intratecal a través de una bomba de infusión totalmente implantable. También incluye la estimulación espinal, una técnica mínimamente invasiva que consiste en el posicionamiento de electrodos en el espacio epidural, conectados a un generador de pulso que se implanta subcutáneo y genera pulsos que buscan suprimir el estímulo nocivo. En este artículo se hará la descripción de las consideraciones anestésicas que se deben tener con sistemas de liberación de medicamentos implantables, dispositivos de estimulación medular y de nervio periférico. Adicionalmente, pueden aparecer pacientes portadores de dispositivos de neuromodulación eléctrica o medicamentosa que deben recibir anestesia para someterse a cirugía por razones diferentes a su patología de dolor crónico y deben conocerse sus implicaciones anestésicas. Por lo anterior, es importante conocer y estar familiarizados con los componentes básicos de dichos dispositivos: funcionamiento, medicamentos que utilizan y las potenciales complicaciones que se puedan tener con estos en el contexto perioperatorio, para garantizar un manejo adecuado y la seguridad del paciente.

8.
Rev. bras. ortop ; 57(3): 384-391, May-June 2022. tab, graf
Article in English | LILACS | ID: biblio-1388028

ABSTRACT

Abstract Objective The "Self-report S4-5 sensory and motor function questionnaire (S4-5Q)" is a short questionnaire that aims to assess the function of the sacral segments, S4 and S5, after a spinal cord injury (SCI), with the purpose of replacing the rectal exam test. The aim of the present study was to carry out a cross-cultural adaptation of the S4-5Q to the Brazilian Portuguese language and to investigate the test-retest reliability of this version. Method The translation and cross-cultural adaptation was performed using the methodology of translation and backtranslation. Initially, translations were done by three independent translators. Their synthesis was then submitted to an expert committee for analysis (SCI health professionals); then, the backtranslation to the original language was sent to the original author and, after all the adjustments, the final version was completed. For test-retest reliability, 24 individuals with chronic SCI were recruited (2 evaluations with an interval of 7 to 14 days between them). Statistical analysis was performed using IBM-SPSS (Version 20, SPSS Inc, Chicago, IL, USA) with data pretabulated in Microsoft Excel (Microsoft Corporation, Redmond, WA, USA). Reliability was tested with Cohen Kappa, and internal consistency with Cronbach α, both adopting p < 0.05 as significant. Results In the reliability analysis, the results of all questions showed almost perfect agreement (Kappa > 0.81) and good internal consistency (Cronbach α: 0.65-0.77) between the questions and final classification. Conclusion The cross-culturally adapted S4-5Q is reliable to be applied to the Brazilian population with chronic SCI to determine their S4-5 sensory and motor function.


Resumo Objetivo O "Self-report S4-5 Sensory and Motor Function Questionnaire (S4-5Q)" é um breve questionário de avaliação da função dos segmentos sacrais S4 e S5 após uma lesão medular (LM), cuja finalidade é substituir o exame de toque retal. O objetivo do presente estudo foi realizar uma adaptação transcultural do questionário S4-5Q para a língua portuguesa do Brasil e investigar a confiabilidade teste-reteste desta versão. Método A tradução e a adaptação transcultural foram realizadas utilizando a metodologia de tradução e retrotradução. Inicialmente, as traduções foram realizadas por três tradutores independentes. Sua síntese foi então submetida a um comitê de especialistas (profissionais de saúde com experiência em LM). Em seguida, a retrotradução para o idioma original foi enviada ao autor original, sendo que a versão final foi concluída após todas as adaptações. Para a confiabilidade teste-reteste, foram recrutados 24 indivíduos com lesão medular espinal (LME) em fase crônica (2 avaliações com intervalo de 7 a 14 dias entre elas). A análise estatística foi realizada no IBM-SPSS (Version 20, SPSS Inc, Chicago, IL, USA) com dados pré- tabulados no programa Microsoft Excel (Microsoft Corporation, Redmond, WA, EUA). A confiabilidade foi testada por meio do coeficiente Kappa de Cohen, e a consistência interna foi medida através do α de Cronbach, ambas adotando p < 0,05 como significante. Resultados Na análise de confiabilidade, os resultados de todas as perguntas apresentaram concordância quase perfeita (Kappa > 0,81) e boa consistência interna (α de Cronbach: 0,65-0,77) entre as perguntas e a classificação final. Conclusão O questionário S4-5Q adaptado culturalmente é confiável, podendo ser aplicado à população brasileira com LME crônica, com o objetivo de avaliar a função sensorial e motora nos segmentos sacrais S4-S5.


Subject(s)
Humans , Sacrococcygeal Region , Spinal Cord Injuries , Cross-Cultural Comparison , Surveys and Questionnaires
9.
Rev. bras. ortop ; 57(3): 521-523, May-June 2022. graf
Article in English | LILACS | ID: biblio-1388024

ABSTRACT

Abstract Idiopathic hypertrophic pachymeningitis is rare cause of neurological symptoms with myelopathy due to spinal cord compression. We report a case of pachymeningitis, which was manifested primarily by tetraparesis after low-energy trauma and recurrence the myelopathy symptoms after 5 years of surgery. The patient, a 19-year-old woman, was subjected to extensive investigation without evidence of any underlying disease. A meningeal biopsy was performed and showed an unspecific inflammatory process with extensive fibrosis of the dura mater. These findings, associated with the exclusion of other causes, suggest idiopathic hypertrophic pachymeningitis.


Resumo A paquimeningite hipertrófica idiopática é uma causa rara de sintomas neurológicos apresentando mielopatia por compressão da medula espinhal. Relatamos um caso de paquimeningite com manifestação primária de tetraparesia após trauma de baixa energia e recorrência dos sintomas de mielopatia 5 anos após a cirurgia. A paciente, uma mulher de 19 anos, foi submetida a extensa investigação sem evidências de qualquer doença de base. Uma biópsia da meninge revelou processo inflamatório inespecífico com extensa fibrose da dura máter, também visualizado no período perioperatório. Esses achados, associados à exclusão de outras causas, sugerem o diagnóstico de paquimeningite hipertrófica idiopática.


Subject(s)
Humans , Female , Adult , Spinal Cord/pathology , Spinal Cord Compression , Hypertrophy , Meningitis/physiopathology
10.
Medicina UPB ; 41(1): 38-50, mar. 2022. tab
Article in Spanish | LILACS, COLNAL | ID: biblio-1362691

ABSTRACT

Las urgencias oncológicas son complicaciones comunes de la evolución natural del tumor o de su manejo. Algunas pueden presentarse de manera sutil y ser pasadas por alto, lo que aumenta la morbimortalidad. El objetivo de esta revisión narrativa es recopilar información actualizada de las principales complicaciones oncológicas, para ello se realizó una revisión de artículos originales, revisiones sistemáticas y narrativas en bases de datos como Scopus, SciELO, PubMed, ScienceDirect y en el buscador Google Scholar. Se seleccionaron 63 referencias que mostraran información relevante acerca de las urgencias oncológicas planteadas para el desarrollo del artículo. En la revisión se discute que las complicaciones pueden clasificarse de acuerdo con su origen en infecciosas (neutropenia febril), metabólicas (síndrome de lisis tumoral e hipercalcemia maligna) y obstructivas (síndrome de vena cava superior, obstrucción intestinal, compresión medular y taponamiento cardiaco). El diagnóstico requiere un alto índice de sospecha, el médico debe tener la capacidad resolutiva y el conocimiento necesarios para el manejo y hacer uso racional de los recursos diagnósticos. Es necesario adoptar medidas terapéuticas que impacten positivamente en el pronóstico y que reduzcan la morbimortalidad.


Oncological emergencies are common complications resulting from the natural evolution of the tumor or its management; however, some of them may be subtle or even overlooked, which contributes to greater morbidity and mortality. Our aim was to gather updated information on the main oncological complications. A narrative literatura review was performed by searching for original articles, systematic reviews and narratives, in databases such as Scopus, SciELO, PubMed, ScienceDirect and in the Google Scholar search engine. 63 references were selected that addressed relevant information about the oncological emergencies raised for the development of the article. According to their origin, complications can be classified into infectious (febrile neutropenia), metabolic (tumor lysis syndrome and malignant hypercalcemia) and obstructive (superior vena cava syndrome, intestinal obstruction, spinal cord compression and cardiac tamponade). Facing these complications requires a high level of suspicion; the physician must be able to resolve each complication and have the necessary knowledge to approach each case, with a rational use of diagnostic resources. It is also necessary to adopt therapeutic measures that positively impact patients. patient prognosis, decreasing morbidity and death.


As urgências oncológicas são complicações comuns da evolução natural do tumor ou do seu manejo. Algumas podem apresentar-se de maneira sutil e ser passadaspor encima, o que aumenta a morbimortalidade. O objetivo desta revisão narrativa é recopilar informação atualizada das principais complicações oncológicas, para isso se realizou uma revisão de artigos originais, revisões sistemáticas e narrativas em bases de dados como Scopus, SciELO, PubMed, ScienceDirect e no buscador Google Scholar. Se selecionaram 63 referências que mostraram informação relevante sobre às urgências oncológicas apresentadas para o desenvolvimento do artigo. Na revisão se discuteque as complicações podem classificar-se de acordo com a sua origem em infecciosas (neutropenia febril), metabólicas (síndrome de lise tumoral e hipercalcemia maligna) e obstrutivas (síndrome de veia cava superior, obstrução intestinal, compressão medular e entupimento cardíaco). O diagnóstico requere um alto índice de suspeita, o médico deve ter a capacidade resolutiva e o conhecimento necessário para o manejo e fazer uso racional dos recursos diagnósticos. É necessário adotar medidas terapêuticas que impactem positivamente no prognóstico e que reduzam a morbimortalidade.


Subject(s)
Humans , Neoplasms , Spinal Cord Compression , Superior Vena Cava Syndrome , Cardiac Tamponade , Tumor Lysis Syndrome , Emergencies , Febrile Neutropenia , Hypercalcemia
11.
Rev. mex. anestesiol ; 45(1): 30-34, ene.-mar. 2022. tab, graf
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1389177

ABSTRACT

Resumen: Introducción: El manejo correcto de la vía aérea en los pacientes politraumatizados es crucial, ya que es necesario tener una vía aérea segura y proveer adecuada ventilación sin emperorar una probable lesión medular. Objetivo: Determinar el efecto de la maniobra de fijación en línea (MILS del inglés Manual In-Line Stabilisation) en la clasificación de Cormack-Lehane (CL), así como la correlación con el índice de masa corporal (IMC). Material y métodos: En un estudio descriptivo en el Centro Hospitalario del Estado Mayor Presidencial en la Ciudad de México se incluyeron 56 pacientes con estado físico ASA I a IV. El anestesiólogo realizó la laringoscopía directa bajo MILS y valoró el grado de CL. Inmediatamente después se reposicionó al paciente en posición de olfateo, se efectuó nueva laringoscopía directa y se revaloró de nuevo el grado de CL. Resultados: Los grados del CL fueron significativamente diferentes entre la posición MILS versus olfateo. Los grados de CL fueron en su mayoría altos cuando se posicionó al paciente en MILS (75% de los pacientes clasificados entre III y IV) y disminuyeron significativamente al ser cambiados a posición de olfateo. Conclusión: Se observa mejoría del CL cuando se cambia de posición MILS a olfateo.


Abstract: Introduction: Correct airway management of polytraumatized patients is crucial because of the necessity of securing the airway and providing adequate ventilation without worsening a probable spinal cord injury. Objective: Determine the effect of manual inline stabilization (MILS) on Cormack-Lehane classification and if there is any correlation with body mass index (BMI). Material and methods: In a descriptive study at the Centro Hospitalario del Estado Mayor Presidencial in Mexico City, we included 56 patients with ASA physical status I to IV. The anesthesiologist performed direct laryngoscopy while MILS was performed and observed the CL grade. Immediately after, the patient was repositioned into the sniffing position, direct laryngoscopy was performed, and the CL grade was observed again. Results: The CL grades observed were significantly different between MILS vs. Sniffing position. CL grades were mainly high when positioned in MILS (75% classified as grades III and IV) and diminished significantly when changed to the sniffing position. Conclusion: Improvement of CL grade was observed when changing from MILS to sniffing position.

12.
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1390280

ABSTRACT

RESUMEN El hematoma espinal es una entidad clínica poco frecuente. Se necesita de una alta sospecha clínica para su diagnóstico precoz y tratamiento oportuno. Habitualmente se presenta en forma de deterioro neurológico súbito debida a la compresión medular mecánica producida por sangre en el canal medular. Presentamos el caso de un paciente de sexo masculino de 53 años, consumidor de bebidas alcohólicas (ron paraguayo) en forma diaria que presenta un deterioro neurológico brusco comprometiendo miembros superiores e inferiores. Con la resonancia magnética se llega al diagnóstico de hematoma epidural a nivel de C4-C5 y mielopatía compresiva de los segmentos adyacentes.


ABSTRACT The spinal hematoma spinal is a infrequent clinical entity. A high clinical suspicion is needed for early diagnosis and timely treatment. It usually presents as a sudden neurological deterioration due to mechanical spinal cord compression caused by blood in the spinal canal. We present the case of a 53-year-old male patient, a daily consumer of alcoholic beverages (Paraguayan rum) who presented sudden neurological deterioration compromising upper and lower limbs. Magnetic resonance imaging leads to a diagnosis of epidural hematoma at the C4-C5 level and compressive myelopathy of the adjacent segments.

13.
Rev. bras. ciênc. vet ; 29(1): 19-26, jan./mar. 2022. il.
Article in English | LILACS, VETINDEX | ID: biblio-1393195

ABSTRACT

Injuries involving the spine are frequent in dogs and knowledge of them is important to define the patient's treatment and prognosis. The objective of this retrospective study was to describe the epidemiological profile of animals and lesions in the cervical (C1-5) and cervicothoracic (C6-T2) spine diagnosed through tomographic examination. Compilation of computed tomography (CT) reports for the referred regions was carried out in a diagnostic center between 01/04/2017 and 30/04/2020, with or without contrast, from the clinical routine, in order to relate the most common lesions and their locations, as well as the species, breeds and ages most affected. A total of 1164 CT scans were performed in the period, 57.56% (n=670/1164) for the spine, with 89.7% (n=601/670) reports accessed, where both regions referred to here totaled 26.95% of the studies (n=162/601). Male mixed-breed dogs (MBD) showed the most lesions. For the cervical spine, the most identified lesion was disk extrusion and the site was C3-C4, while the mean age for lesions was 8.09±3.55 years. As for cervicothoracic, disk mineralization was more frequent and the mean age for lesions was 6.96±2.93 years. It was concluded that the spine is the main target of CT scans, that lesions related to the intervertebral disk were the main ones identified, and older MBD animals are the main ones affected.


As lesões envolvendo coluna vertebral são frequentes em animais de companhia, podendo ocorrer à nível vertebral, medula espinal, disco intervertebral, meninges ou raízes nervosas, e o conhecimento das mesmas é importante para definir o tratamento e prognóstico do animal. O objetivo desse estudo retrospectivo foi descrever o perfil epidemiológico dos animais e das lesões em coluna vertebral cervical (C1-5) e cervicotorácica (C6-T2) diagnosticadas por meio de exame tomográfico. Realizou-se a compilação de laudos de tomografias computadorizadas para as referidas regiões realizadas em centro diagnóstico comercial, entre 01/04/2017 a 30/04/2020, contrastadas e não-contrastadas, provenientes da rotina clínica, a fim de relacionar as lesões, raças e locais mais comuns. Foram realizados 1164 exames tomográficos no período avaliado, sendo 57,56% (n=670/1164) para a coluna, com 89,7% dos laudos acessados (n=601/670), sendo que as regiões cervical e cervicotorácica somaram 26,95% dos estudos (n=162/601). Em ambas regiões, os cães sem raça definida (SRD) machos foram os que mais demonstraram lesões. Para a coluna cervical, a lesão mais identificada foi extrusão de disco e o local mais afetado foi C3-C4, enquanto a média de idade para lesões foi 8,09±3,55 anos. Já para cervicotorácica, a mineralização de disco foi mais frequente e média de idade para ocorrência de lesões foi de 6,96±2,93 anos. Concluiu-se que a coluna vertebral foi o principal alvo de tomografias, as lesões relacionadas ao disco intervertebral foram as mais identificadas, sendo animais SRD com idade avançada os mais acometidos.


Subject(s)
Animals , Cats , Dogs , Spinal Injuries/diagnostic imaging , Spine/diagnostic imaging , Thorax/abnormalities , Tomography, X-Ray Computed/veterinary , Cats/injuries , Dogs/injuries , Intervertebral Disc/injuries
14.
Rev. bras. ciênc. vet ; 29(1): 27-35, jan./mar. 2022. il.
Article in English | LILACS, VETINDEX | ID: biblio-1393204

ABSTRACT

For vertebromedullary injuries, epidemiological knowledge is essential to guide the choice of the most effective diagnostic method. The objective of this retrospective study was to describe the epidemiological profile of animals and thoracolumbar and lumbosacral spine lesions diagnosed by computed tomography scan. A compilation of CT scan reports for the aforementioned regions performed in a comercial diagnostic center from 04/01/2017 to 04/30/2020, contrasted and non-contrasted, from routine, was performed in order to list the most common lesions and their locations, as well as the species, breeds and ages most affected. There were 1164 CT scans performed in the period evaluated, all of them in dogs, 57,56% (n=670) for the spine, with 89,7% reports accessed (n=601), where the regions mentioned here added up to 73,05% studies (n=439). In both regions, male French Bulldog dogs had the most injuries. For the thoracolumbar region, disk mineralization, followed by extrusion, were the most frequent injuries, while the site was T12-13 and the mean age 6,5±3,63 years old. In the lumbosacral, disk protrusion was most frequent, the most affected site was L7-S1 and age 6,65±3,79 years. It was concluded that the spine is the main target of CT scans, and that lesions related to the intervertebral disk were the main ones identified, with chondrodystrophic animals being more predisposed to injury.


Para lesões vertebromedulares é indispensável o conhecimento epidemiológico para direcionar a escolha do método diagnóstico mais eficaz. O objetivo desse estudo retrospectivo foi descrever o perfil epidemiológico dos animais e das lesões em coluna vertebral toracolombar e lombossacral diagnosticadas através de exame tomográfico. Realizou-se a compilação de laudos de tomografias computadorizadas para as referidas regiões realizadas em centro diagnóstico comercial, entre 01/04/2017 a 30/04/2020, contrastadas e não-contrastadas, provenientes da rotina, a fim de relacionar as lesões e seus locais de ocorrência, bem como a espécie, raças e idades mais comuns. Foram realizados 1164 exames tomográficos no período avaliado, sendo 57,56% (n=670) para a coluna, com 89,7% laudos acessados (n=601), nos quais as regiões toracolombar e lombossacral somaram 73,05% dos estudos (n=439). Em ambas as regiões, os cães Bulldog Francês machos foram os que mais apresentaram lesões. Para a região toracolombar, a mineralização de disco, seguida pela extrusão, foram as lesões mais frequentes, enquanto o local foi T12-13 e a média de idade 6,5±3,63 anos. Na lombossacral, a protusão de disco foi mais frequente, o local mais afetado foi L7-S1 e idade de 6,65±3,79 anos. Concluiu-se que a coluna vertebral é o principal alvo de tomografias, e que as lesões relacionadas ao disco intervertebral foram as principais identificadas, sendo os animais condrodistróficos mais predispostos a lesões.


Subject(s)
Animals , Cats , Dogs , Spinal Injuries/veterinary , Spine/diagnostic imaging , Tomography, X-Ray Computed/veterinary , Cats/injuries , Dogs/injuries , Intervertebral Disc/injuries , Lumbar Vertebrae/injuries , Lumbosacral Region/abnormalities
15.
Acta méd. peru ; 39(1): 89-95, ene.-mar. 2022. graf
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1383391

ABSTRACT

RESUMEN Introducción: Las hernias del disco torácico calcificadas son poco frecuentes y su abordaje representa un desafío quirúrgico cuando son gigantes y sintomáticas. La discectomía transtorácica extrapleural puede considerarse un abordaje seguro para resecar el fragmento de disco calcificado y descomprimir la médula espinal. Caso clínico: Hombre de 53 años con dorsalgia media irradiada a región inframamaria y dificultad progresiva para deambular, paraparesia proximal moderada, nivel sensitivo T8 y retención urinaria. Las imágenes demostraron una gran hernia de disco T6-7 calcificada que causaba una compresión severa de la médula espinal. El paciente se sometió a discectomía transtorácica extrapleural T6-7 más corpectomía parcial T6 sin fusión. El paciente toleró bien el procedimiento sin complicaciones y las imágenes postoperatorias al mes de la cirugia demostraron la descompresión de la médula espinal. En el seguimiento, la dorsalgia irradiada, el nivel sensitivo, la paraparesia y la retención urinaria mejoraron.


ABSTRACT Introduction: Calcified thoracic disc herniation are rare and their approach represents a surgical challenge when they are large and symptomatic. Extrapleural Transthoracic discectomy can be considered a safe approach to resection of the calcified disc fragment and spinal cord descompression. Clinical case: 53-year-old man with middle dorsalgia radiating to the inframammary region and progressive difficulty walking, proximal paraparesis moderate, sensory level T8 and urinary retention. The images demonstrated a large T6-7 disc herniation calcified causing severe spinal cord compression. The patient underwent T6-7 extrapleural transthoracic discectomy plus T6 partial corpectomy without fusion. The patient tolerated the procedure well without complications and postoperative imaging demonstrated descompression of spinal cord. At followup, irradiated dorsalgia, paraparesis, sensitive level and urinary retention improved.

16.
Motriz (Online) ; 28: e10220006821, 2022. tab
Article in English | LILACS | ID: biblio-1375940

ABSTRACT

Abstract Aim: This study aims to characterize the stress, recovery, mood, and motivation together with the training load of athletes with cervical spinal cord injury (CSCI) during a period of resumption of wheelchair rugby (WCR) training. Additionally, it aims to compare the psychological and load training aspects during a competitive preseason and determine the correlations between training load, mood, stress, and recovery. Methods: We evaluated variables such as mood (Brazilian Mood Scale, BRAMS), stress and recovery (Recovery-Stress Questionnaire for Athletes, RESTQ-Sport 76) and training load (Subjective Perception of Effort - SPE) of eight high-performance athletes of wheelchair rugby with CSCIs at three different times (E1 = returning from vacation, E2 = half of the preseason, and E3 = after 2 months of training) for 2 months at a monthly interval. We also evaluated motivation (Sport Motivation Scale) at E1 and E3. Results: Results indicated few changes during the competitive preseason in terms of stress, recovery, and mood. However, the training load decreased toward the end of this period. Furthermore, we found that physical complaints positively correlated with depression when resuming training. In the middle of the competitive preseason period, we also noted positive correlations between conflict/pressure and fatigue and between fatigue and energy loss. At the end of this period, the SPE and arbitrary units correlated positively with conflict/pressure. Conclusion: We found few changes during the competitive preseason in terms of stress, recovery, and mood but not motivation, which did not change during this period. On the other hand, the training load decreased at the end of the competitive preseason. Furthermore, we observed correlations between training load and psychological aspects at different times.


Subject(s)
Humans , Spinal Cord Injuries/physiopathology , Exercise , Psychology, Sports , Para-Athletes , Stress, Physiological , Wit and Humor , Motivation
17.
J. inborn errors metab. screen ; 10: e20220003, 2022. tab, graf
Article in English | LILACS-Express | LILACS | ID: biblio-1386084

ABSTRACT

Abstract Introduction Mucopolysaccharidoses (MPS) can lead to cervical spinal cord compression (SCC). Diagnostic scores for SCC in MPS use the obliteration of the passage of cerebrospinal fluid in the anterior and posterior spinal cord in the sagittal section of magnetic resonance imaging (MRI). The spinal cord occupation ratio (SCOR) published, by Nouri et al (2018), establishes the spinal cord filling index for the spinal cord, identifying disproportionate spinal cord occupation in the canal. When evaluating congenital canal stenosis, the risk of spinal cord injury has been considered increased when the SCOR is ≥70% in the median sagittal plane or ≥ 80% in the axial plane. Although these values ​​have not been validated for MPS populations, they could be useful. Objective To verify the SCOR in MPS patients with diagnosis of cervical SCC comparing the SCOR with other markers proposed in the existing MPS SCC scores, such as the extent of gliosis, clinical impact and the SCC assessment as represented by the obliteration of CSF flow. Methods We reviewed imaging tests of the cervical spine from MPS patients with previously confirmed SCC, using the SCOR measure in the median sagittal plane, evaluation of the presence and extent of spinal gliosis on MRI, evaluation of the clinical impact using a clinical score and evaluation of the images for the obliteration of cerebral spinal fluid (CSF) flow. Results Thirty-one MRI of 24 different patients were included. The average SCOR was 87.1%. This was lower (81.6%) in patients without gliosis, when compared to those with focal (90.5%) and extensive (97%) gliosis. The only patient with gliosis associated with a lacunar lesion, resulting from an acute compressive injury, had a 68% SCOR, due to the atrophic spinal cord injury. As expected, SCOR was higher in patients with total or partial CSF obliteration, but one among the 3 patients without CSF flow obliteration, with a 76% SCOR, had already developed focal gliosis and mild clinical abnormalities. Patients with more extensive gliosis had higher clinical scores. Four patients had more than one imaging scan evaluated. SCOR upward trend showed an annual average increase of 3.8%. Discussion & Conclusions The use of SCOR allows the diagnosis of cervical spinal canal stenosis in an objective way. It is possible that the cut-off values used by Nouri et al in patients with congenital stenosis could be useful to diagnose cervical stenosis in MPS patients, preceding the finding of CSF flow obstruction, presence of gliosis or clinical abnormalities. Furthermore, the use of SCOR may assist in the longitudinal evaluation of disease progression. Better follow-up and timely diagnosis allows for scheduling of surgery at the best clinical moment, minimizing complications.

18.
Article in Chinese | WPRIM | ID: wpr-940207

ABSTRACT

ObjectiveTo investigate the effect of calycosin-mediated glucoprotein130/Janus kinase/signal transducer and activator of transcription factor (GP130/JAK/STAT) signaling pathway on oxidative injury of astrocytes in spinal cord. MethodAstrocytes in rat spinal cord were isolated and identified by immunofluorescence detection of glial fibrillary acidic protein (GFAP). The cells were respectively pre-treated with 5, 10, 20 μmol·L-1 calycosin for 12 h, and then 100 μmol·L-1 H2O2 (24 h) was added to induce oxidative injury. Cell counting kit-8 (CCK-8) assay was employed to detect cell proliferation and select the optimal concentration of calycosin. The following experimental groups were designed: control group, model group (100 μmol·L-1 H2O2), calycosin group (20 μmol·L-1 calycosin), calycosin + LY294002 group (20 μmol·L-1 calycosin + 10 μmol·L-1 LY294002), and calycosin + Stattic group (20 μmol·L-1 calycosin + 3 μmol·L-1 Stattic). CCK-8 assay and immunofluorescence method were used to detect the proliferation of cells and flow cytometry was applied to detect cell apoptosis and cycle. The protein expression of phosphorylated (p)-JAK2, p-STAT3, p-protein kinase B (Akt), GP130, and interleukin-6 (IL-6) was detected by Western blotting. ResultCompared with the control group, the model group showed low proliferation activity and high apoptosis rate of cells (P<0.05). Compared with the model group, calycosin (20 μmol·L-1) group displayed high proliferation activity and low apoptosis rate of cells (P<0.05). Compared with calycosin (20 μmol·L-1) group, both phosphatidylinosirtol-3-kinases (PI3K) inhibitor LY294002 and STAT3 inhibitor Stattic significantly reduced the proliferation activity and increased the apoptosis rate of cells (P<0.05). The protein expression of p-JAK2, p-STAT3, p-Akt, GP130, and IL-6 in the model group was higher than that in the control group (P<0.05), and the expression of the above indicators was lower in each treatment group than in the model group (P<0.05). ConclusionCalycosin can promote the proliferation and inhibit the apoptosis of astrocytes with oxidative injury by inhibiting the phosphorylation of PI3K/Akt pathway and JAK2/STAT3 pathway.

19.
Article in Chinese | WPRIM | ID: wpr-940110

ABSTRACT

ObjectiveTo investigate the effect of calycosin-mediated glucoprotein130/Janus kinase/signal transducer and activator of transcription factor (GP130/JAK/STAT) signaling pathway on oxidative injury of astrocytes in spinal cord. MethodAstrocytes in rat spinal cord were isolated and identified by immunofluorescence detection of glial fibrillary acidic protein (GFAP). The cells were respectively pre-treated with 5, 10, 20 μmol·L-1 calycosin for 12 h, and then 100 μmol·L-1 H2O2 (24 h) was added to induce oxidative injury. Cell counting kit-8 (CCK-8) assay was employed to detect cell proliferation and select the optimal concentration of calycosin. The following experimental groups were designed: control group, model group (100 μmol·L-1 H2O2), calycosin group (20 μmol·L-1 calycosin), calycosin + LY294002 group (20 μmol·L-1 calycosin + 10 μmol·L-1 LY294002), and calycosin + Stattic group (20 μmol·L-1 calycosin + 3 μmol·L-1 Stattic). CCK-8 assay and immunofluorescence method were used to detect the proliferation of cells and flow cytometry was applied to detect cell apoptosis and cycle. The protein expression of phosphorylated (p)-JAK2, p-STAT3, p-protein kinase B (Akt), GP130, and interleukin-6 (IL-6) was detected by Western blotting. ResultCompared with the control group, the model group showed low proliferation activity and high apoptosis rate of cells (P<0.05). Compared with the model group, calycosin (20 μmol·L-1) group displayed high proliferation activity and low apoptosis rate of cells (P<0.05). Compared with calycosin (20 μmol·L-1) group, both phosphatidylinosirtol-3-kinases (PI3K) inhibitor LY294002 and STAT3 inhibitor Stattic significantly reduced the proliferation activity and increased the apoptosis rate of cells (P<0.05). The protein expression of p-JAK2, p-STAT3, p-Akt, GP130, and IL-6 in the model group was higher than that in the control group (P<0.05), and the expression of the above indicators was lower in each treatment group than in the model group (P<0.05). ConclusionCalycosin can promote the proliferation and inhibit the apoptosis of astrocytes with oxidative injury by inhibiting the phosphorylation of PI3K/Akt pathway and JAK2/STAT3 pathway.

20.
Article in Chinese | WPRIM | ID: wpr-939993

ABSTRACT

ObjectiveTo investigate the changes of bone mineral density of distal femur and proximal tibia in patients with spinal cord injury. MethodsNine inpatients with spinal cord injury in Beijing Bo'ai Hospital for rehabilitation from November, 2018 to January, 2021 were recruited. The bone mineral density of distal femur, proximal tibia, total hip and femoral neck at admission and six months after admission was measured. ResultsCompared with the results of admission, the bone mineral density of distal femur, proximal tibia, total hip and femoral neck decreased significantly six months after admission (∣Z∣ > 2.265, P < 0.01). The percentage of decreased bone mineral density in the femoral neck was inversely correlated with the lower extremity movement score at the second measurement (r = -0.515, P = 0.035). ConclusionWithin one year after the onset of spinal cord injury, the bone mineral density of distal femur and proximal tibia decreases.

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