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Resumen: Los cormos de malanga son tallos subterráneos con alto valor nutrimental por su contenido de carbohidratos y proteínas, además de ser altamente digestivos. El almidón que se extrae de ellos puede ser utilizado en la encapsulación de microorganismos probióticos, de gran importancia para la salud. El objetivo de este trabajo fue desarrollar un suplemento alimenticio con características funcionales, usando bacterias ácido lácticas (BAL) (Lactobacilos casei), encapsuladas en almidón de malanga (Xanthosoma sagittifolium). El suplemento se realizó mezclando 150 mL de pulpa de fruta cocida (mango o manzana) con 400 mL de suero de leche (pH de 6.0), a 45 ± 1 °C, hasta conseguir la consistencia deseada (449.9 mPas/s a una temperatura de 25 ºC). Posteriormente, se adicionaron 1 % o 2 % de almidón de malanga (p/v) y 10 mL de cultivo probiótico por cada 100 mL de mezcla. Se deshidrató a 80 ºC y 150 ºC con flujo de aire de 20 mL/min para manzana y 8 mL/min para mango mediante secado por aspersión. El rendimiento fue de 12 %, con una viabilidad de las BAL en el suplemento deshidratado a los 3 meses de almacenamiento superior a 1 x 108 UFC/g. La ausencia de bacterias coliformes, así como de salmonella y shigella, indican que los suplementos son inocuos y aptos para consumo. La composición nutrimental del suplemento de manzana obtenido fue2.23 % de fibra, 5.93 % de grasa, 4.95 % de proteína y un 79 % de hidratos de carbono; el suplemento de mango, el contenido fue 0.59 % de fibra, 7.6 % de grasa, 4.2 % de proteína y 80.20 % de hidratos de carbono. El almidón de malanga permitió la microencapsulación de las BAL y mantener su viabilidad durante el almacenamiento de los suplementos alimenticios desarrollados con base en suero de leche y fruta.
Abstract: Malanga corms are an underground stem with a high nutritional value as it contains carbohydrates and proteins, in addition to being highly digestive; The starch extracted from them can be used in the encapsulation of probiotic microorganisms, which are of great importance for human health. The objective of this work was to develop a food supplement with functional characteristics, added with lactic acid bacteria (Lactobacillus casei) (LAB), using malanga (Xanthosoma sagittifolium) starch. The supplement was obtained by mixing 150 mL of cooked fruit pulp (mango or apple) with 400 mL of sweet whey (pH of 6.0), at a temperature of 45 ± 1 °C until the desired consistency (449.9 mPas/s at a temperature of 25 °C) was achieved. Subsequently, 1 % or 2 % of malanga starch (p/v) and 10 mL of probiotic cultures were added per each 100 mL of mixture. it was then dehydrated at 80 ºC and 150 °C with an air flow of 20 mL/min for apple and 8 mL/min for mango by spray drying. The yield was 12 %, with viability of LAB in the dehydrated supplement at 3 months of storage higher than 1 x 108 CFU/g. The absence of coliform bacteria, as well as Salmonella and Shigella, indicate that the supplements are safe and suitable for consumption. The nutritional composition of the apple supplement was 2.23 % fiber, 5.93 % fat, 4.95 % protein and 79 % carbohydrates; the mango supplement content was 0.59 % fiber, 7.6 % fat, 4.2 % protein and 80.20 % carbohydrates. The malanga starch allowed the LAB microencapsulation and the maintenance of their viability during the storage of sweet whey and fruit-based food supplements.
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Background: Premature ejaculation is the most common cause of sexual dysfunction. There is no consensus on the treatment protocol due to poor understanding of the underlying mechanisms. Therefore, the present pilot study was conducted to compare the efficacy of topical eutectic mixture for premature ejaculation (TEMPE) spray with lidocaine gel for the treatment of premature ejaculation. Methods: After obtaining ethics approval and written informed consent, 100 patients meeting the inclusion and exclusion criteria were included. Baseline values of intravaginal ejaculation time (IELT) and international index of erectile function (IIEF) were recorded. Patients were randomly assigned into group A (lidocaine plus prilocaine spray) and group B (lidocaine gel). After 4 weeks of treatment IELT and IIEF score were recorded. The findings were noted and analysed. Results: Both the groups were similar in terms of demographic and baseline characteristics. There was a significantly higher improvement in IELT and IIEF score following treatment in group A as compared to group B. The incidence of side effects was lower in group A as compared to group B. Conclusions: We recommend that the use of TEMPE spray for the treatment of premature ejaculation as it is better than lidocaine gel.
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Background: Pain in the postoperative period is of particular concern. It is a major barrier in the uptake of circumcision. There are various systemic and local analgesics for the management of postoperative pain. However, data regarding efficacy is scarce. Therefore, the present pilot study was conducted to compare the efficacy of lidocaine and prilocaine spray with oral analgesics for the relief of pain. Methods: After obtaining ethics approval and written informed consent, 100 patients meeting the inclusion and exclusion criteria were included. After circumcision, patients were randomized into group A (Lidocaine and prilocaine spray) and group B (Oral analgesics). Pain was assessed by visual analogue scale (VAS) score and patient reported comfort levels were assessed in the postoperative period till 72 hours. Findings were noted and analysed. Results: Both the groups were similar in terms of demographic characteristics and baseline characteristics. The VAS score was significantly lower in group A and the patient-reported comfort level was significantly more in group A. Conclusions: We recommend that the lidocaine and prilocaine spray is better in relieving pain in the postoperative period following circumcision as compared to oral analgesics.
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Objective:To confirm the transportation and evaporation efficiency of micro droplets sprayed by high-pressure nozzles from purified tritium-containing wastewater with carrier gas in the horizontal evaporation chamber.Methods:A scale test bench with a single high-pressure nozzle had been built based on design conditions and similarity criteria to explore the designed evaporation characteristics of generated micro droplets in the horizontal evaporation chamber. At the same time, combined with experimental data, a suitable evaporation model was constructed using the Discrete Phase Model (DPM) in Ansys Fluent. On this basis, further simulation and analysis were conducted on the evaporation process and efficiency under the condition of multiple nozzles in the desighed horizontal evaporation chamber.Results:For single nozzle tests, the particle size of micro droplets along the nozzle centerline was between 12-50 μm and the particle size distribution was similar to the Rosin-Rammler distribution. Besides, the relative light intensity decreased exponentially with distance, indicating that the particle size and concentration of micro droplets both decreased rapidly, which means the evaporation rate of micro droplets was rapid. For the simulation of multiple nozzles injection in the desighed horizontal evaporation chamber, even for the hardest design condition, the evaporation percentage reached up to 99%, and small amount of the escaping micro droplets continued to evaporate during the process of mixing with other process exhaust until complete evaporation in the vertical chimney section.Conclusions:Under the conditions of desighed sprayed particle size distribution, typical operating conditions and the incoming flow similar to the supposed area, the complete evaporation of the micro droplets can be basically achieved in the horizontal evaporation chamber, so as to ensure the complete evaporation of purified tritium-containing wastewater from the outlet of the chimney.
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Objective To optimize the spray drying process of Banlangen(Isatidis Radix)formula granules based on quality by design(QbD)concept.Methods Using powder yield and the contents of uridine,adenosine,guanosine,and(R,S)-goitron as the critical quality attributes(CQAs),Plackett-Burman design was used to screen out critical process parameters(CPPs)for inlet temperature,spray pressure,liquid temperature,pump speed,and liquid relative density.The central-composite design(CCD)test was used to optimize the CPPs,which were screened.Based on the quadratic polynomial regression model,the design space of spray drying process of Banlangen(Isatidis Radix)formula granules was established,and further validated by experiments.Results Plackett-burman test results show that liquid relative density and inlet velocity are the key parameters for the study.The variance analysis results of CCD test showed that the constructed model in a good prediction ability,since the P-values of model was less than 0.01 and P-values of items lack of fit was more than 0.05.The optimized design space of CPPs was the liquid relative density 1.05-1.08,and pump speed 30%-40%.Conclusion Based on the QbD concept,the design space for the spray drying process of Banlangen(Isatidis Radix)formula granules can improve the stability of its process and help ensure the consistency of product quality.
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Objective:To study the effects of low-dose dexmedetomidine via nasal spray on preoperative anxiety and tracheal intuba-tion induced stress response in elderly patients with maxillofacial surgery using heart rate variability(HRV).Methods:60 elderly pa-tients underwent maxillofacial surgery were randomly divided into the dexmedetomidine group(group D)and the control group(group C).Patients in the group D were treated with nasal spray of dexmedetomidine at 45 min preoperatively.Those in the group C were giv-en the same dose of normal saline spray at the same time.All patients were given intravenous combined with inhalation general anes-thesia.The hemodynamics,HRV index,sedation score and BIS value of the 2 groups of patients were compared at 3 time points,be-fore operation(T0),entrance(T1)and tracheal intubation(T2)respectively.Results:At T1,the average score of Ramsay in group D and group C was 2.8±0.7 and 1.1±0.39,BIS 87.3±6.1 and 97.4±0.5,SD1 20.9±7.0 and 15.4±5.4,SDNN 30.9±6.6 and 37.1±7.0,LF/HF 1.3±0.3 and 2.6±0.4,respectively(P＜O.01).At T2,the average score of SD1 in group D and group C was 10.4±3.5 and 7.7±3.1,SDNN 59.2±6.5 and 70.1±7.1,LF/HF 5.l±0.5 and 7.5±0.5,respectively(P＜0.01).Conclusion:Low-dose dexmedetomidine nasal spray can effectively relieve the preoperative anxiety of elderly patients in maxillofacial surgery and reduce the stress response of tracheal intubation.
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italic>Anoectochilus roxburghii liquid (spray, a hospital preparation of Wu Mengchao Hepatobiliary Hospital of Fujian Medical University) has shown a good clinical treatment effect during the COVID-19 pandemic, but its material basis and mechanism of action are still unclear. In this study, network pharmacology and molecular docking methods were used to predict the molecular mechanism of A. roxburghii liquid against COVID-19, and pharmacodynamic experiments in vitro were conducted to study the interaction between the current targets with clear preventive and therapeutic effects and the key components of A. roxburghii liquid. UPLC-MS and database were used to compare and analyze the active ingredients in the liquid, and 17 potential active ingredients with good drug-like properties were screened by in vivo pharmacokinetics process in SwissADME database. SwissTargetPrediction and GeneCards were searched to find 93 common targets. Cytoscape 3.8.2 software was used to construct the "component-target" network map, and the Metascape platform was used for gene function annotation and pathway enrichment analysis. It was found that the extract could regulate the positive response to external stimuli, inflammatory response, cytokine production and other biological processes by binding the active ingredients such as isorhamnetin, kaempferol, luteolin, quercetin and apigenin to the common targets (NOS3, MPO, MMP3, etc.), and play an anti-COVID-19 role. In the angiotensin-converting enzyme 2 (ACE2) activity inhibition assay, it was found that the stock solution of A. roxburghii liquid (for spray), and the supernatant after removing polysaccharides (mainly containing flavonoids) could to some extent inhibit the activity of ACE2. Crucially, in the experiment of 2019-nCOV-S pseudovirus infecting HEK-293T-ACE2 cells, we found that A. roxburghii liquid may exert anti-COVID-19 effects by blocking the binding of SARS-CoV-S protein to ACE2.
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In this study, fluvoxamine maleate sustained-release pellet system tablets were prepared and were used to evaluate their release behaviors in vitro. Fluvoxamine maleate pellets were prepared using centrifugal-spherization method and coated by fluidized bed as bottom-spray. The multi-unit sustained-release pellets and appropriate excipients for prescription volumes were mixed uniformly and then compressed to tablets. Screening and determining the optimal formulation of drug loaded pellets through L8 (24) Taguchi experiment. Using Minitab software to design a DOE experiment with 24 partial factors, including material temperature, fan speed, atomization pressure, and spray rate to optimize the bottom spray coating process. Taking monostearate glycerol ester with a particle size of 24-40 mesh as the main diluent for tableting to relieve the delamination phenomenon between pellets and excipients during tablet pressing and reduce mechanical damage to the coating film. By examining the powder fluidity indexes such as angle of repose, bulk density, tapped density, and Hausner ratio of mixed particles, it was found that the flowability and compressibility are good and suitable for direct compression. Evaluate the basic properties of the sustained-release tablets, investigate the in vitro release behavior and study the release mechanism. The results of in vitro release test showed that the self-made sustained-release tablets could disintegrate into independent pellet units in phosphate buffer at pH 6.8 and release slowly within 24 h, which conformed to the first-order drug release model. The fluvoxamine maleate sustained-release pellet system tablets meet the requirements of preparation design and has a great commercial prospect.
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Sprays have gained significant attention and widespread use due to their numerous advantages, including rapid action, safety, and convenience. They are widely used in various fields such as dermatology, respiratory disease treatment, wound repair, and central nervous system targeted drug delivery. With the in-depth research of new drugs and modern pharmaceutics, the development ideas of sprays are more diverse, and the application scenarios are increasingly extensive. In this review the clinical application status of sprays and the latest research progress were summarized. Then the quality control parameters were briefly introduced，which provided reference for the research and development of sprays.
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Despite the record speed of developing vaccines and therapeutics against the SARS-CoV-2 virus, it is not a given that such success can be secured in future pandemics. In addition, COVID-19 vaccination and application of therapeutics remain low in developing countries. Rapid and low cost mass production of antiviral IgY antibodies could be an attractive alternative or complementary option for vaccine and therapeutic development. In this article, we rapidly produced SARS-CoV-2 antigens, immunized hens and purified IgY antibodies in 2 months after the SARS-CoV-2 gene sequence became public. We further demonstrated that the IgY antibodies competitively block RBD binding to ACE2, neutralize authentic SARS-CoV-2 virus and effectively protect hamsters from SARS-CoV-2 challenge by preventing weight loss and lung pathology, representing the first comprehensive study with IgY antibodies. The process of mass production can be easily implemented in most developing countries and hence could become a new vital option in our toolbox for combating viral pandemics. This study could stimulate further studies, optimization and potential applications of IgY antibodies as therapeutics and prophylactics for human and animals.
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Microbial cellulases present biotechnological potential to be used in several industries, including food, brewery and wine, industrial waste for chemical feedstock, animal feed, pulp and paper, agriculture, textile and detergent production. In this work, cellulases produced by the thermophilic Bacillus sp. SMIA-2 in submerged cultures containing sugarcane bagasse, corn steep liquor and passion fruit rind flour were spray-dried, in an attempt to improve their stability for industrial purposes. The cellulases were spray dried and analyzed before and after the drying process and subsequent storage. A Central Composite Design (CCD) 23 was used to investigate the effect of different concentrations of arabic gum and microcrystalline cellulose, as well as the spray dryer inlet temperature on the cellulase spray drying process. The results evidenced that the combination of 1.0 % (w/v) arabic gum and 1.0% (w/v) microcrystalline cellulose, at inlet temperature of 70 °C, was effective in maintaining the activities of both avicelases (avicel-hydrolyzing enzymes) and carboxymethylcellulases (carboxymethylcellulose-hydrolyzing enzymes - CMCase). The dried avicelase was completely preserved when stored at 5oC, while the CMCase retained 89% of its activity, which indicates promising potential for industrial uses, especially in detergent formulations.
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Wheat (Triticum aestivum L.) is one of the world's most essential cereal crops, serving as a staple food for a significant portion of the global population. In the pursuit of achieving higher yields in contemporary agriculture, the use of chemical fertilizers poses an increased environmental risk. However, the application of Nano urea offers a potential solution to mitigate this risk to a certain extent. To address this objective, a field experiment was conducted during the Rabi seasons of 2022-2023 at the A trial was executed in the rural area of Kanpur district of Mandhana, located 10 km from Kanpur in Uttar Pradesh, during the Rabi season of 2022-23. The experimental design involved two main factors: Factor-1 Nitrogen (at 50%, 75%, and 100% levels) and Factor-2 Foliar Spray (at one time Nano urea and two time Nano urea, with 4 ml/l). A control group was included, and the experiment was laid out in a Randomized Block Design (RBD) with 13 treatments in three replications. The results indicated that the combination of 100% nitrogen along with a foliar spray of 4 ml/L Nano urea had a significant positive impact on growth, yield, and various yield parameters. Treatment 6 demonstrated the highest values for plant height (95.66 cm), Dry matter accumulation (1014.09 g m-2), number of tillers m-2 (417.44), Leaf area index at 90 DAS (4.85), effective ear head per (m-2) (282.66), grains per ear head (65.75), test weight (48.52 g), grain yield (46.15 quintals/ha), and straw yield (57.92 quintals/ha). The study's results demonstrated a generally positive effect of combined Nano urea with traditional NPK nutrient supply on the growth and yield parameters of wheat in irrigated conditions.
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Aims: Conventional urea fertilizer has been critical in enhancing castor yields. However, nano urea, a game-changing technology in modern agriculture, provides a significant advancement in terms of sustainable and efficient crop production.Study Design: The experiment was conducted in a Randomized block design (RBD) with eight treatments and three replications.Place and Duration of Study: Tapioca and Castor Research Station in Yethapur during the Kharif season of 2022.Methodology: The major objective is to increase hybrid castor growth and production under rainfed circumstances by foliar application of nano urea. The castor hybrid YRCH 1 with an RDF of 60:30:30 NPK kg ha-1 was chosen for the study. The experimental details viz; T1 - 100% N through Urea –RDF, T2 - 50 % of recommended basal N + Nano urea foliar spray @ 2 ml/l at 30 and 60 DAS, T3 - 50 % of recommended basal N + 2 % Urea foliar spray at 30 and 60 DAS, T4 - 75 % of recommended basal N + Nano urea foliar spray @ 2 ml/l at 30 and 60 DAS, T5 - 75 % of recommended basal N+ 2 % Urea foliar spray at 30 and 60 DAS, T6 - 100 % of recommended basal N + Nano urea foliar spray @ 2 ml/l at 30 and 60 DAS, T7 - 100 % of recommended basal N + 2 % Urea foliar spray at 30 and 60 DAS.Results: According to the findings of the study, applying 100% of the recommended basal N + Nano urea foliar spray @ 2 ml/l at 30 and 60 DAS is advantageous to the crop and improves the growth and yield characteristics of hybrid castor under rainfed conditions. However, when compared to other treatments, foliar application of nano urea with 50% indicated basal N resulted in significantly lower growth and yield.Conclusion: The major objective is to increase hybrid castor growth and production under rainfed circumstances by foliar application of nano urea
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The studies on the operational parameters of selected nozzles were conducted in the laboratory using a patternator with the operational parameters of four types of nozzles (hollow cone, 3-way discharge nozzle (3D), flood type, and solid cone nozzle), five operating pressures (400, 500, 600, 800, and 1000 kPa), and five nozzle heights (0.2, 0.3, 0.4, 0.5, and 0.6 m). The effects of independent variables on spray discharge, droplet size, uniformity coefficient, droplet density, and spray angle were studied. It was observed that the discharge rate increased by increasing the operating pressure, and discharge varied for different types of nozzles. The Hallow cone nozzle exhibited a minimum discharge rate of 0.515 l/min, and the maximum discharge rate recorded was 1.546 l/min for the 3D nozzle. The droplet size decreases with increasing operating pressure. As the operating pressure increased, the size of the droplets formed into fine particles. The maximum droplet size of 251 µm was produced by the 3D nozzle, and the minimum was 117 µm by the Hallow cone nozzle. The spray uniformity increased with an increase in operating pressure. Spray uniformity was minimal in cases of low operating pressure because of the size of the droplets. Droplet density increased with an increase in operating pressure. Spray angle increases with increasing operating pressure. The spray angle is decreased by increasing the nozzle height because of gravity. Spray angles are different for different nozzles.
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Drought stress significantly hampers crop growth and yield by negatively impacting various biochemical and physiological plant processes. This study aimed to assess drought tolerance in traditional rice varieties using Poly Ethylene Glycol 6000 (PEG 6000) and focused on the effectiveness of melatonin applied through both seed treatment and foliar spray in mitigating the effects of drought stress. The optimal drought screening conditions were determined at a PEG concentration of -4 bars. As the PEG concentration increased, key factors such as germination percentage, vigor index, root length, and shoot length decreased. This indicates that PEG can be a useful tool for early selection of drought tolerant rice varieties. Melatonin (N-acetyl-5-methoxytryptamine), known for alleviating abiotic stress, showed positive effects on seed germination at 200 ppm concentration. The study observed that stomatal closure is a natural response to drought stress, but melatonin application induced partial stomatal opening. Notably, a foliar spray of 100 ppm melatonin demonstrated better recovery from drought stress compared to the 200 ppm concentration. In conclusion, the research suggests that seed treatment with 200 ppm melatonin and foliar spraying with 100 ppm melatonin are the most effective approaches for reducing the adverse effects of drought stress in rice plants.
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Efficient utilization of water and fertilizers is important for maximizing yield for moth bean production through improvement the nutrient use efficiency under arid ecosystem. The aim of this study was to evaluate the effects of irrigation and nitrogen fertilizers on growth, yield and nutrient content of moth bean in the western zone of Rajasthan during 2020 & 2021. Treatments included three levels of nitrogen (N1:15 kg N as basal + foliar spray of urea (2%) at flowering stage, N2: 15 kg N + foliar spray of urea (2%) at pod development stage and N3: 15 kg N + foliar spray of urea (2%) at flowering and pod development stages) and levels three levels of irrigation (I1: single irrigation at branching stage, I2: two irrigation at branching + pod development stages and I3: two irrigation at flowering + pod development stages) were laid down in factorial combinations of randomized block design with three replications. The results revealed that 15 kg N + foliar spray of urea (2%) at flowering and pod development stage recorded significantly higher nitrogen, phosphorus and potassium content in seed and haulm over 15 kg N + foliar spray of urea (2%) at flowering stage and 15 kg N + foliar spray of urea (2%) at pod development stage. However, the phosphorus content in seed and haulm was not significantly influenced by N3 and statistically equivalent with N2 and N1 during 2020 and 2021. Potassium content in seed showed significant enhancement under N3, while K content in haulm was not affected significantly during 2020 and pooled basis. Further, irrigation management practices did not show any significant improvement on N, P, K content in seed and haulm during years of 2020 and 2021. While, N content in seed and haulm was significantly improved under I2 over I3 and I1 on pooled basis. Thus, 15 kg N as basal application + foliar spray of urea (2%) at flowering and pod development stages with two irrigations at branching + pod development stages improved the nutrient content in moth bean in arid condition.
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A study on “Synthesis, Characterization and Impact of Nano-urea on Growth and Yield of Wheat in Inceptisol” was conducted at Division of Soil Science, College of Agriculture, Pune during rabi 2021. The object of this experiment is to synthesize and characterize nano-urea at post graduate laboratory of Soil Science, College of Agriculture, Pune and which is named as COAP (College of Agriculture, Pune). Nano-urea was synthesized from granular conventional urea and characterised for size of nano particles by using scanning electron microscope. The experiment consisted of twenty one combinations of treatment based on 3 levels of recommended doses of nitrogen (0, 50, 75%) and six nitrogen levels for foliar sprays and water spray as a control which was replicated twice in factorial completely randomized Design (FCRD). The foliar sprays of nitrogen consisted of four levels of COAP nano-urea @ 50, 100, 150 and 200 ppm, IFFCO nano-urea @ 160 ppm and conventional urea @ 10,000 ppm applied at 30 and 50 DAS.It could be revealed that average size of COAP (22.419 nm) and IFFCO (22.773 nm) nano-urea was almost same. Results revealed that conjoint application of 75% nitrogen along with two foliar sprays of conventional urea @10,000 ppm, COAP nano-urea @ 200 ppm and IFFCO nano-urea @ 160 ppm taken at 30 and 50 DAS for wheat recorded significantly higher periodical plant height and leaf area at 35 and 55 DAS. Significantly higher plant height was reported with combine application of 75% RDN along with two foliar sprays of urea @ 10,000 ppm (76.83 cm) which was statistically at par with nano-urea of IIFCO (76.20 cm) and COAP (74.20 cm) than rest of the treatment at 55 DAS. In case of leaf area, application of 75% RDN along with two foliar sprays of either conventional urea @ 10,000 ppm, IFFCO nano- urea @ 160 ppm and COAP nano-urea @ 200 ppm at 35 and 55 DAS. Application of 75% recommended dose of nitrogen along with two foliar sprays of 10,000 ppm conventional urea recorded significantly higher grain (45 g pot-1) and straw yield (65.39 g pot-1) of wheat which was found to be significantly at par with 75% RDN + IFFCO nano-urea @160 ppm (44.91 and 62.87 g pot-1) and 75% RDN + COAP nano-urea @ 200 ppm (44.83 and 60.66 g pot-1).
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Background: Globally unexpected 219 million malaria cases occurred in 2021, with 90% of these cases happening in the WHO Africa region and unexpected 435,000 malaria transmissions worldwide, with children less than five years being the most-at-risk (61%) of malaria infections (World Malaria Report, 2021). In 2019, IRS coverage was 94.6%. This was reason enough to assess contributing factors leading to not reaching targeted 100% of the households mapped despite massive resources. Methods: The study adopted analytical cross-sectional design. The study area was Migori County (Awendo, Uriri, Rongo, Suna East, Suna West and Nyatike sub counties) where IRS had been implemented in four sessions. The study period November 2021 to April 2022. The respondents sample size was determined using Cochran (1963) for a single population of 1,000 households. The respondents were randomly selected villages from purposively selected Migori County. Kenyatta University Ethics Review Committee and NACOSTI provided ethical clearance. Quantitative data analyzed using SPSS version 2.6 and thematically for qualitative data. A Chi-squared test used to compute statistically significant differences between independent variables at p value <0.05. Results: Some 249 (90%) of the respondents confirmed their houses were IRS- covered while 32 (10%) of the houses were not sprayed because they were not informed in advance (p value <0.000). Conclusions: Using the Chi-squared test of significance the spray operators` arrival time for IRS activities affected the respondents daily calendar of events significantly (p=0.013, <0.05) resulting into respondents’ non-participation and unmet targets.
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Vegetables are one of the main elements in terms of ensuring a person's food security and nutritional well-being. Integrated application of macronutrients coupled with adequate incorporation of micronutrients is one of the key factors for quality vegetable production. For ensuring maximum vegetable production with superior quality foliar nutrition is the better alternative in the era of climate change. Foliar application is the easiest and most effective way to administer micronutrients as compared to other methods. Trace elements such as iron (Fe), zinc (Zn), manganese (Mn), molybdenum (Mo), boron (B), chlorine (Cl), copper (Cu), and nickel (Ni) are essential for vegetable crops. The primary goal of this review article is to investigate the merits of micronutrients and the production potential of various vegetable crops through foliar nutrition. Additionally, this study aims to clarify the role of micronutrients in quality vegetable production. Several studies suggested that the exogenous application of micronutrients has a tremendous effect on overall growth and quality in a variety of crops. Many researchers have demonstrated that applications of Boron @250ppm significantly influenced the fresh weight of fruit, number of fruits per plant, number of seeds per plant, germination%, vigour index and root and shoot lengths of seedlings in sweet pepper. Various researchers also concluded that the application of Zn @1000 ppm + B @200 ppm + Mo @50 ppm provides a significant impact on head diameter, volume of head, chlorophyll a, chlorophyll b and chlorophyll total in cabbage.
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In pursuit of high yield today’s agriculture cultivars put the environment at greater risk by the inputs of chemical fertilizers. Using Nano urea we can minimize the inputs damage upto a certain extent. With this objective, field experiment was carried out during Rabi seasons of 2022-2023 at Crop Research Farm, Department of Agronomy, SHUATS, Prayagraj, Uttar Pradesh on topic “Effect of nano urea and foliar spray of urea on growth and yield of wheat”. The treatment include two factors, Factor- 1 Nitrogen (50 %, 75%, 100%) and Factor- 2 Foliar Spray (2ml/L nano urea, 4 ml/L nano urea, 2% urea) and one control was laid out in Randomized Block Design (RBD) with 10 treatments and three replications. Result revealed that 100% nitrogen along with foliar spray of 4ml/L nano urea recorded significant effect on Growth, yield and yield parameters. Treatment 6 recorded maximum plant height (101.62 cm), dry weight (21.95 g) number of tillers/running row (85.02), number of effective tillers/m2 (340.08), number of grains/spike (54.16), test weight (48.52 g), grain yield (6.30 t/ha) and straw yield (7.98 t/ha).