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1.
J. biomed. eng ; Sheng wu yi xue gong cheng xue za zhi;(6): 1229-1234, 2021.
Article in Chinese | WPRIM | ID: wpr-921865

ABSTRACT

With the continuous progress of materials science and biology, the significance of biomaterials with dual characteristics of materials science and biology is keeping on increasing. Nowadays, more and more biomaterials are being used in tissue engineering, pharmaceutical engineering and regenerative medicine. In repairing bone defects caused by trauma, tumor invasion, congenital malformation and other factors, a variety of biomaterials have emerged with different characteristics, such as surface charge, surface wettability, surface composition, immune regulation and so on, leading to significant differences in repair effects. This paper mainly discusses the influence of surface charge of biomaterials on bone formation and the methods of introducing surface charge, aiming to promote bone formation by changing the charge distribution on the surface of the biomaterials to serve the clinical treatment better.


Subject(s)
Biocompatible Materials , Osteogenesis , Regenerative Medicine , Tissue Engineering
2.
Article in English | IMSEAR | ID: sea-174379

ABSTRACT

The aim of this study is evaluate two different techniques of modification of titanium surface and to compare the surface roughness levels, surface wettability and surface configuration of variously treated surfaces of titanium (commercially pure titanium grade I). Commercially pure titanium (Grade I) sheets of 0.2mm thick and 4.5mm diameter are used for this study. Blasting of titanium with Alumina, combined with Acid etching using Hydrofluoric acid, Hydrochloric acid and sulfuric acid. And Oxidation treatment is done with Sodium hydroxide, Surface roughness levels were measured with the help of surface profilometer and surface analyzer. Surface wettability is measured with help of contact angle measurement using light microscope and surface configuration was determined with the help of scanning electron microscopy. Scanning electron microscopic studies concluded that samples with alumina blasting followed by acid etching revealed uniform rough configuration of the surface.

3.
Article in Korean | WPRIM | ID: wpr-84193

ABSTRACT

Purpose: This study aims to get the fundamental data which is necessary to the development direction of implant surface treatment hereafter, based on the understanding the surface structure and properties of titanium which is suitable for the absorption of initial tissue fluid by researching effects of additional surface treatments for sandblasted with large grit and acid-etched(SLA) titanium on surface micro-roughness, static wettability, fibronectin adsorption. Materials and Method: In the Control groups, the commercial pure titanium disks which is 10mm in diameter and 2mm in thickness were treated with HCI after sandblasting with 50micrometer Al2O3. The experiment groups were made an experiment each by being treated with 1) 22.5% nitric acid according to SLA+ASTM F86 protocol, 2) SLA+30% peroxide, 3) SLA+NaOH, 4) SLA+Oxalic acid, and 5) SLA+600degree C heating. In each group, the value of Ra and RMS which are the gauges of surface roughness was measured, surface wettability was measured by analyzing with Sessile drop method, and fibronectin adsorption was measured with immunological assay. The significance of each group was verified by (SPSS, ver.10.0 SPSS Inc.) Kruskal-Wallis Test.(alpha=0.05) And the correlation significance between Surface micro-roughness and surface wettability, surface roughness and fibronectin adsorption, and surface wettability and fibronectin adsorption was tested by Spearman's correlation analysis. Result: All measure groups showed the significant differences in surface micro-roughness, surface wettability, and fibronectin adsorption.(p0.05) Conclusion: Surface micro-roughness and surface wettability rarely affected the absorption of initial tissue fluid on the surface of titanium.


Subject(s)
Absorption , Adsorption , Fibronectins , Heating , Hot Temperature , Nitric Acid , Titanium , Wettability
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