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1.
Chinese Journal of Radiology ; (12): 868-872, 2022.
Article in Chinese | WPRIM | ID: wpr-956743

ABSTRACT

Objective:To investigate the MRI and pathological features of intramuscular fibro-adipose vascular anomaly (FAVA).Methods:The clinical and imaging data of 44 patients with intramuscular FAVA confirmed by pathology from December 2012 to March 2021 in Henan Province People′s Hospital were retrospectively analyzed. Twenty-five females and 19 males were included, with the age of (15±6), from 5 to 29 years old. The clinical and MRI features including the type, location, boundary, signal intensity, enhancement mode and degree, and the vascular flow voids in the lesion were summarized and compared with pathological results.Results:The thigh and calf muscles were involved in 1 patient simultaneously, and 1 site was involved in 43 patients, including 20 calf muscles, 15 thigh muscles, 5 forearm muscles, 1 upper arm muscle, 1 gluteal muscle, and 1 shoulder muscle. The gastrocnemius muscle of lower leg was most commonly involved (13/44), followed by soleus muscle (10/44) and quadriceps femoris muscle (9/44). All the lesions were solid on MRI, including 24 cases of focal mass type, 15 cases of diffuse infiltration type and 5 cases of local infiltration type. The long axis of all the lesions were consistent with the long axis of the muscles. All lesions showed inhomogeneously moderate hyperintensity on T 1WI and T 2WI, and significantly hyperintensity on fat suppression T 2WI. All lesions showed tortuous and dilated abnormal vessels, of which 18 cases showed vascular flow voids. Thrombosis was found in 10 cases. On contrast-enhanced imaging, the lesions showed moderate to obvious inhomogeneous enhancement. Pathologically, the diseased skeletal muscle was infiltrated by fibrous tissue, fat components, irregular abnormal veins and vessels, which led to inhomogeneous MRI signals. Among the 7 patients who underwent human PIK3CA gene mutation detection, and 6 were mutant. Conclusions:Intramuscular FAVA has certain characteristics in clinic, MRI imaging and histopathology, and its MRI signal characteristics can reflect its complex pathological components.

2.
Rev. cuba. obstet. ginecol ; 45(4): e512, oct.-dic. 2019.
Article in Spanish | LILACS, CUMED | ID: biblio-1126712

ABSTRACT

RESUMEN Introducción: El síndrome de Klippel Trenaunay Weber es una enfermedad vascular congénita, de causas desconocidas, caracterizada por hemangiomas planos, crecimiento excesivo de huesos y tejido blando, y venas varicosas. Cuando se asocia al embarazo incrementa la morbilidad y mortalidad materna y fetal. Objetivo: Describir dos casos clínicos de gestantes con este síndrome las cuales fueron atendidas en el Hospital Ginecobstétrico Docente "Ramón González Coro" en La Habana, Cuba. Métodos: Estudio descriptivo, retrospectivo, de dos casos mediante técnica de recolección de información, análisis de la historia clínica y búsqueda de literatura actualizada. El mismo se efectuó conforme a las reglamentaciones y principios éticos existentes para la investigación en humanos. No fue necesario que las pacientes ofrecieran su consentimiento informado. Presentación de casos: Los dos casos presentados fueron gestantes adolescentes a las cuales se les dio seguimiento en consulta multidisciplinaria y se les realizó cesárea a las 38 semanas, la primera por riesgo de sangrado por las varicosidades pelvianas y la segunda por indicación neurológica. Se obtuvieron en ambos casos recién nacidos femeninos, de 2620 y 3200 gramos respectivamente y en buenas condiciones. Conclusiones: Debe realizarse una correcta anamnesis durante los controles prenatales para identificar los factores de riesgo que se relacionan con esta entidad que es poco frecuente, pero está relacionada con una gran morbilidad. Es indispensable la actuación en equipo y la evaluación integral de estos casos por un grupo especializado de angiólogos, ginecobstetras, anestesistas, cirujanos, clínicos, y de otras especialidades, para lograr un resultado óptimo(AU)


ABSTRACT Introduction: Klippel Trenaunay Weber syndrome is a congenital vascular disease, of unknown causes, characterized by flat hemangiomas, overgrowth of bones and soft tissue, and varicose veins. When associated with pregnancy, it increases maternal and fetal morbidity and mortality. Objective: To describe two clinical cases of pregnant women with this syndrome, which were treated at the Ramón González Coro Gynecobstetric Teaching Hospital in Havana, Cuba. Methods: A descriptive, retrospective study of two cases using the information collection technique, analysis of the medical history, and search for updated literature. It was carried out in accordance with existing regulations and ethical principles for human research. Patients were not required to offer their informed consent. Case reports: The two cases presented were pregnant adolescents who were followed up in a multidisciplinary consultation and underwent caesarean section at 38 weeks, the first due to risk of bleeding as result of pelvic varicosities and the second due to neurological indication. In both cases, female newborns, 2620 and 3200 grams respectively, were obtained in good conditions. Conclusions: Correct anamnesis must be carried out during prenatal controls to identify the risk factors that are related to this entity, which is rare, but is related to high morbidity. Team action and comprehensive evaluation of these cases, by a specialized group of angiologists, gynecologists, anesthetists, surgeons, clinicians, and other specialties, are essential to achieve an optimal result(AU)


Subject(s)
Humans , Female , Pregnancy , Adolescent , Risk Factors , Klippel-Trenaunay-Weber Syndrome/diagnosis , Hemangioma/etiology , Medical History Taking/methods , Review Literature as Topic , Medical Records , Epidemiology, Descriptive , Retrospective Studies
3.
Health Sciences Journal ; : 28-34, 2017.
Article in English | WPRIM | ID: wpr-997831

ABSTRACT

Introduction@#This study aimed to describe retinal microvascular changes in patients diagnosed to have stroke and determine the association between retinal microvascular changes and type of stroke (lacunar and non-lacunar).@*Methods@#This is a cross-sectional descriptive study conducted among stroke patients seen at the Neurology Ward and Neurology Out-Patient Clinic of the UERM Memorial Medical Center. The patients' demographic characteristics and risk factors were obtained through a standardized questionnaire. Retinal photographs of both eyes were taken in eligible patients who consented to join the study. Retinal vascular changes were identified and their association with the type of stroke was determined.@*Results @#Thirty-seven patients, 64% of whom had small artery occlusion type of lacunar stroke, were enrolled in the study. The most prevalent retinal abnormalities for each type of stroke were AV nicking and focal arteriolar narrowing. The prevalence of abnormal retinal findings between patients with lacunar stroke and non-lacunar stroke were compared and showed insufficient evidence to demonstrate a statistical significance between abnormal retinal findings and lacunar stroke.@*Conclusion @#There is no significant association between abnormal retinal findings and lacunar stroke.


Subject(s)
Stroke , Stroke, Lacunar
4.
Article in English | IMSEAR | ID: sea-159462

ABSTRACT

Tracheostomy is a routine life-saving operative procedure in the event of airway obstruction especially in faciomaxillary injuries. Bleeding is the most common complications of tracheostomy, innominate artery (IA) of normal width reaching second tracheal ring is very rare, and injury to IA can be a catastrophic complication. We reported a case of 40-year-old male presented with profuse bleeding from oral and nasal cavity following road traffic injury. During tracheostomy, there was a sudden forceful gush of blood coming out of incision site, warning a major vessel injury. Right-sided trap door thoracotomy procedure was performed, and the avulsed right IA was repaired as a life-saving procedure.


Subject(s)
Accidents, Traffic/surgery , Adult , Brachiocephalic Trunk/injuries , Brachiocephalic Trunk/surgery , Humans , Male , Thoracotomy/methods , Tracheostomy/adverse effects , Tracheostomy/methods , Wounds and Injuries/surgery
5.
Neurointervention ; : 15-23, 2009.
Article in English | WPRIM | ID: wpr-730151

ABSTRACT

PURPOSE: Clinical implementation of subtraction computed tomographic angiography (CTA) is limited due to motion artifact and/or long processing time. We evaluated the utility of a motion-corrected subtraction CTA technique for visualization of intra- and extra-cranial vascular lesions. MATERIALS AND METHODS: Pre- and post-contrast CT images were obtained in the target region of 53 consecutive patients which were consisted of 36 patients with 53 lesions and 17 normal patients. The source images were transferred to a personal computer (PC) and were automatically post-processed within one minute using novel motion-corrected subtraction CTA. The image quality of subtraction and non-subtraction CTAs was compared in each lesion category and lesion location using 3-point scale and Chi square test. RESULTS: The image quality of subtraction CTA was better than those from non-subtraction CTA (p<0.05) especially in the skull base lesions, such as carotid-cavernous fistulas, aneurysms in the cavernous internal carotid artery (ICA), and steno-occlusive lesions of the distal ICA, and extracranial lesions such as facial arteriovenous fistulas. CONCLUSION: The PC-based motion-corrected subtraction CTA technique allows fast generation of postprocessed images and can provide improved visualization of vascular anatomy and pathologies adjacent to bone in the skull base and head and neck areas.


Subject(s)
Humans , Aneurysm , Angiography , Arteriovenous Fistula , Artifacts , Carotid Artery, Internal , Fistula , Head , Microcomputers , Neck , Pathology , Skull Base
6.
Article in English | WPRIM | ID: wpr-88669

ABSTRACT

OBJECTIVE: We investigated the incidence of the vascular abnormalities associated with spontaneous intracerebral hemorrhage (ICH) using three-dimensional computed tomographic angiography (3D-CTA). METHODS: We prospectively assessed consecutive 76 patients with spontaneous intracerebral hemorrhage (ICH) who underwent 3D-CTA between June 2003 and May 2005. The patients with a recent history of trauma or mainly subarachnoid hemorrhage were excluded. We investigated relationship between vascular abnormality and ICH location. The findings of 3D-CTA were classified as one of three patterns with ICH; type A (without evidence of vascular abnormality), type B (with no vascular abnormality as the source of hemorrhage, but with incidental vascular abnormality), and type C (presence of a vascular abnormality as the source of hemorrhage). RESULTS: Sites of ICH were lobar 26, basal ganglia 23, thalamus 17, posterior fossa 6 and dominant intraventricular hemorrhage (IVH) 4. Among 76 patients, sixteen (21.1%) vascular abnormalities were noted excluding 13 cases of stenoocclusive disease. Sixteen cases included 6 cases of cerebral aneurysms (7.9%), 5 moyamoya diseases (6.6%), 4 arteriovenous malformations (5.3%) and 1 dural sinus thrombosis (1.3%). Lobar ICH (30.8%) had a higher vascular abnormalities than other types, and younger age (<40) group had a higher incidence of vascular abnormalities than old age group. The patterns of 3D-CTA include sixty cases (79.0%) of type A, 6 cases (7.8%) of type B and 10 cases (13.2%) of type C. The vascular abnormalities were found in 8 (13.5%) of 59 hypertensive patients and 8 (47.0%) of 17 non-hypertensive patients (p=0.006). CONCLUSION: 3D-CT angiography is considered a useful screening tool for ICH patients with suspected cerebrovascular abnormalities and should be considered in such clinical settings, especially in lobar type and in non-hypertensive younger patients.


Subject(s)
Humans , Angiography , Arteriovenous Malformations , Basal Ganglia , Cerebral Hemorrhage , Hemorrhage , Incidence , Intracranial Aneurysm , Mass Screening , Prospective Studies , Sinus Thrombosis, Intracranial , Subarachnoid Hemorrhage , Thalamus
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