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1.
J. pediatr. (Rio J.) ; 98(2): 204-211, March-Apr. 2022. tab, graf
Article in English | LILACS-Express | LILACS | ID: biblio-1375771

ABSTRACT

Abstract Objective: Evaluate the effectiveness of a children's soap with physiological pH in maintaining cutaneous pH and moisture of the newborn (NB)'s skin after the first bath. Methods: Randomized, controlled and double-blind clinical trial in a rooming-in of a tertiary maternity hospital in southern Brazil with 204 newborns > 34 gestational weeks. Gestational and obstetric history was evaluated, and newborns were randomized into two groups according to the product applied in the bath: the control group (CG), which used common liquid soap with pH 7.0 and experimental group (EG), which used children's liquid soap with pH 5.8. Evaluation was made immediately before and after bath with skin pH measurement, corneometry and clinical parameters (erythema, scaling and moisture), on the forehead, abdomen and thigh. Results: There was no difference between groups regarding gestational, obstetric and family history (p > 0.05). In CG, skin pH increased in the abdomen and thigh (p < 0.05). In EG there was an improvement in clinical parameters after bathing with: increased moisture, less erythema and less scaling (p < 0.05). On the forehead, there was a significant increase in pH after bathing (p < 0.001) similar in both groups, although no use of soap. There was no difference in corneometry between groups after bathing. Conclusions: Children's liquid soap with physiological pH maintained the acidic skin pH and moisture of the newborn's skin after the first bath, which reinforces the importance of using products with physiological pH in the hygiene of newborns. Registration number RBR-9ky84vd.

2.
Esc. Anna Nery Rev. Enferm ; 26: e20210138, 2022. tab
Article in Portuguese | LILACS, BDENF | ID: biblio-1360436

ABSTRACT

Resumo Objetivo Produzir um vídeo instrucional para enfermeiros sobre o banho de ofurô em recém-nascidos pré-termo e validar seu conteúdo. Método Estudo metodológico de desenvolvimento tecnológico com ênfase na validação de conteúdo, conduzido em três etapas: revisão exploratória da literatura, produção da tecnologia educacional do tipo vídeo instrucional e validação por especialistas. Os dados foram sistematizados e organizados em planilhas e as análises foram conduzidas no pacote estatístico R. Para validar o conteúdo, aplicaram-se o Índice Kappa, para medir a concordância entre as respostas, e o Índice de Validade de Conteúdo, para estimar a representatividade do item. Resultados As publicações sobre a técnica (n=3) identificadas na revisão de literatura foram utilizadas para a produção do vídeo. O vídeo simula o cuidado em unidade neonatal e tem duração de 13 minutos. No processo de validação, o vídeo foi considerado, no geral, com representatividade de conteúdo adequada e obteve índice de concordância entre as respostas quase perfeito. Dois itens foram avaliados como "adequados com alterações" e modificados. Conclusão e implicações para a prática O material produzido foi considerado adequado para ser utilizado na capacitação de enfermeiros sobre a técnica e compartilhamento de informações, contribuindo para o cuidado de enfermagem humanizado e seguro em unidades neonatais.


Resumen Objetivo Producir un video instructivo para enfermeros sobre el baño de ofuro en recién nacidos prematuros y validar su contenido. Método Estudio metodológico de desarrollo de tecnología con énfasis en la validación de contenido, realizado en tres etapas: revisión exploratoria de la literatura, producción de tecnología educativa de tipo video instructivo y validación por expertos. Los datos fueron sistematizados y organizados en hojas de cálculo y los análisis se realizaron en el paquete estadístico R. Para validar el contenido se aplicó el Índice Kappa para medir la concordancia entre las respuestas y el Índice de Validez del Contenido para estimar la representatividad del ítem. Resultados Para la producción del video se utilizaron publicaciones sobre la técnica (n = 3) identificadas en la revisión de la literatura. El video simula la atención en una unidad neonatal y tiene una duración de 13 minutos. En el proceso de validación, el video se consideró, en general, con adecuada representación de contenido y con un índice de concordancia casi perfecto entre las respuestas. Dos ítems se evaluaron como "adecuados con cambios" y se modificaron. Conclusión e implicaciones para la práctica El material producido fue considerado por los especialistas como adecuado para uso en la formación de enfermeros sobre la técnica y el intercambio de información, contribuyendo para la atención de enfermería humanizada y segura en las unidades neonatales.


Abstract Objective To produce an instructional video for nurses about hot tub bath for preterm newborns and to validate its content. Method Methodological study of technological development with emphasis on content validation, conducted in three stages: exploratory literature review, production of an instructional video educational technology and expert validation. The data were systematized and organized in spreadsheets and the analyses were carried out in the statistical package R. For content validation, the Kappa Index was calculated to measure response agreement and the Content Validity Index was employed to estimate item representativeness. Results Publications about the technique (n=3) identified in the literature review were used for video production. The video simulates care in a neonatal unit and lasts 13 minutes. In the validation process, the video was considered, in general, to have an adequate content representation and had an almost perfect response agreement index. Two items were assessed as "adequate after revision" and modified. Conclusion and implication for the practice The produced material was considered by the experts as suitable for use in training nurses on the technique and sharing information, contributing to a humanized and safe nursing care in neonatal units.


Subject(s)
Humans , Female , Infant, Newborn , Adult , Pediatric Nursing/education , Baths/nursing , Educational Technology , Infant, Premature , Methods
3.
Rev inf cient ; 100(5): 1-11, 2021. ilus
Article in Spanish | LILACS, CUMED | ID: biblio-1348797

ABSTRACT

Introducción: El p-clorofenol alcanforado es un derivado clorofenólico de uso común como medicación intraconducto en Endodoncia. Son escasos los reportes científicos sobre sus efectos en la musculatura lisa vascular arterial y la regulación del flujo sanguíneo local. Objetivo: Determinar el efecto del p-clorofenol alcanforado sobre la dinámica contráctil del músculo liso vascular arterial en el tiempo. Método: Se realizó una investigación experimental preclínica utilizando 14 anillos de aorta obtenidos de ratas Wistar. Los anillos se colocaron en baño de órganos y se preactivaron con noradrenalina, registrándose luego la tensión desarrollada por el músculo liso vascular tras la adición de p-clorofenol alcanforado durante diferentes intervalos de tiempo. Resultados: El 51,4 porciento de la musculatura lisa vascular se relajó por la acción del p-clorofenol alcanforado. El mayor descenso del tono vascular se produjo entre el tercer y quinto minuto de añadido el medicamento. Las pruebas de Wilcoxon de los rangos con signos evidenciaron diferencias significativas entre la tensión base inicial y la registrada en los diferentes intervalos de tiempo estudiados. Conclusiones: el p-clorofenol alcanforado, induce in vitro, relajación del músculo liso arterial a través de un acoplamiento excitación-contracción de tipo farmacomecánico, la cual se incrementa en función del tiempo(AU).


Introduction: Camphorated p-chlorophenol is a chlorophenolic derivative commonly used as an intra-oral medication in endodontics. Scientific reports on its effects in arterial vascular smooth muscle and local blood flow regulation are scarce. Objective: To determine the effect of camphorated p-chlorophenol on the contractile dynamics of arterial vascular smooth muscle. Method: An experimental and preclinical research was conducted with the use of 14 aortic rings of Wistar rats. The rings were placed in an organ bath and preactivated with noradrenaline, and the tension developed by the vascular smooth muscle at different time intervals was recorded after induction of camphorated p-chlorophenol. Results: Most of the vascular smooth muscle (51.4 percent) relaxed with the use of camphorated p-chlorophenol. The greatest decrease in vascular tone occurred between the third and fifth minute after use the drug. Wilcoxon rank tests showed significant differences between tension observed at baseline and those recorded at the different time intervals studied. Conclusions: Camphorated p-chlorophenol, induces in vitro, relax the arterial smooth muscle through a pharmacomechanical excitation-contraction link, which increases according to the time(AU).


Introdução: O cânfora-clorofenol é um derivado clorofenólico comumente utilizado como medicamento intracanal em Endodontia. Relatórios científicos sobre seus efeitos no músculo liso vascular arterial e na regulação do fluxo sanguíneo local são escassos. Objetivo: Determinar o efeito da cânfora-clorofenol na dinâmica contrátil do músculo liso vascular arterial ao longo do tempo. Método: Foi realizada investigação experimental pré-clínica com 14 anéis aórticos obtidos de ratos Wistar. Os anéis foram colocados em banho de órgãos e pré-ativados com norepinefrina, em seguida, a tensão desenvolvida pela musculatura lisa vascular foi registrada após a adição de cânfora-clorofenol em diferentes intervalos de tempo. Resultados: 51,4 porcento dos músculos lisos vasculares estavam relaxados pela ação do cânfora-clorofenol. A maior diminuição do tônus vascular ocorreu entre o terceiro e o quinto minuto após a adição do medicamento. Os testes de Wilcoxon das faixas com sinais mostraram diferenças significativas entre a tensão base inicial e a registrada nos diferentes intervalos de tempo estudados. Conclusões: O cânfora-clorofenol induz, in vitro, relaxamento da musculatura lisa arterial por meio de um acoplamento excitação-contração do tipo farmacomecânico, que aumenta em função do tempo(AU).


Subject(s)
Animals , Rats , Chlorophenols/administration & dosage , Muscle, Smooth, Vascular/drug effects , Muscle Tonus/drug effects , Intervention Studies , Rats, Wistar , Germany
4.
Chinese Critical Care Medicine ; (12): 593-595, 2021.
Article in Chinese | WPRIM | ID: wpr-909365

ABSTRACT

Objective:To analyze the distribution and composition characteristics of jellyfish stings in various coastal baths in Qinhuangdao City from 2017 to 2019, and to provide scientific basis for the prevention, control and early warning of jellyfish stings.Methods:Statistics and analysis of the age, gender, time of stings, location of injury, first symptoms, and playing time in the sea at the time of the sting, etc. of people with jellyfish stings in various bathing beaches along the coast of Qinhuangdao from 2017 to 2019 (July to August) were conducted.Results:The number of jellyfish stings in the coastal bathing beaches of Qinhuangdao City in 2017, 2018, and 2019 was decreasing year by year, with 1 890, 492, and 171 cases respectively. Among them, Qianshuiwan Bathing Beach and Dongshan Bathing Beach had more stings (60.90% and 35.08% respectively in 2017, 24.39% and 64.23% respectively in 2018, 16.96% and 16.42% respectively in 2019). There was no significant change in the gender and age distribution of jellyfish stings each year [57.99% males in 2017, with a median age of 13 (8, 31) years old; 63.21% males in 2018, with a median age of 25 (8, 29) years old; and 59.65% males in 2019, with a median age of 12 (7, 31) years old]. Stings were mainly located at the lower limbs (the proportion of lower limb injuries: 46.54% in 2018, 45.61% in 2019), followed by upper limbs (upper arm, elbow, forearm), trunk, etc. The first symptom was mainly pain (89.43% in 2018, 38.29% in 2019), followed by rash (64.43% in 2018, 59.43% in 2019), numbness, blisters, etc. Sting incidents mainly occurred from 13:00 to 17:59 (the proportion of sting incidents in this time period in 2018 and 2019 were 68.09% and 52.63%, respectively).Conclusions:Jellyfish stings in coastal baths in Qinhuangdao City are mainly distributed in Qianshuiwan Baths and Dongshan Baths. The management of these sea areas should be strengthened, and scientific publicity and medical rescue should be strengthened to prevent jellyfish stings in peak hours and related baths.

5.
Article in Chinese | WPRIM | ID: wpr-888086

ABSTRACT

Wuwei Ganlu, a formula for medicated bath, consists of medicinal materials of Ephedra sinica, Platycladus orientalis, Myricaria squamosa, Artemisia carvifolia, and Rhododendron anthopogonoides, which is effective in inducing perspiration, resisting inflammation, relieving pain, regulating yellow water disease, and activating blood circulation. On this basis, a variety of formulas for Tibetan medicated bath have been derived for the treatment of diseases in internal organs, joints, nerves, etc. Modern studies have confirmed that Wuwei Ganlu has a good therapeutic efficacy on knee osteoarthritis(KOA). The present study explored the mechanism of Wuwei Ganlu in treating KOA based on network pharmacology and molecular docking. Firstly, the chemical components of Wuwei Ganlu were obtained through literature mining and database retrieval, and corresponding potential targets were predicted according to the BATMAN-TCM database. The protein-protein interaction(PPI) network was obtained after the potential targets were input into the STRING database. The network function modules were analyzed by the Molecular Complex Detection(MCODE) algorithm, and the functions of the modules were annotated to analyze the action mode of Wuwei Ganlu. Secondly, the related targets of KOA were collected through the DisGeNET database, and the overlapping targets were confirmed to analyze the mechanism of Wuwei Ganlu in treating KOA. Finally, the key targets were selected for molecular docking with the main components of Wuwei Ganlu to verify the component-target interaction. A total of 550 chemical components and 1 365 potential targets of Wuwei Ganlu were obtained. PPI analysis indicated that this formula could exert the effects of oxidation-reduction, inflammation resistance, bone absorption, bone mineralization, etc. Nineteen common targets were obtained from the intersection of potential targets of Wuwei Ganlu and KOA disease targets. It was found that the Wuwei Ganlu mainly acts on nuclear factor-κB(NF-κB), interleukin-1 beta(IL1β), tumor necrosis factor(TNF), IL6, IL1 receptor antagonist(IL1 RN), and prostaglandin-endoperoxide synthase-2(PTGS2) to treat KOA. Among the 550 chemical components of Wuwei Ganlu, 252 potential active components were docked with TNF and 163 with PTGS2, indicating good binding of the components with potential key targets. The study preliminarily explored the mechanism of Wuwei Ganlu in treating KOA to provide a reference for the further development and utilization of Tibetan medicated bath that has been included in the UN Intangible Cultural Heritage.


Subject(s)
Databases, Factual , Drugs, Chinese Herbal , Humans , Inflammation , Molecular Docking Simulation , Osteoarthritis, Knee
6.
Article | IMSEAR | ID: sea-213372

ABSTRACT

Background: Seitz bath in post-perineal surgery minimizes pain by reducing anal sphincter tone and also maintains hygiene. The aim and objective of this retrospective study is to compare the effect of warm versus regular room temperature seitz bath. The article clears the concept of seitz bath. The seitz bath gives psychological satisfaction of dressing to patient and helps in boosting the concept of hygiene in their mind.Method: Study design for this study was comparative study of warm and room temperature seitz bath on 60 patients by convenience sampling operated for perineal diseases from 01 November 2019 to 30 March 2020 with written informed consent of patient and fulfilling ethical requirements at Rajiv Gandhi Medical College, Thane, Mumbai. Patients with immunocompromised status and comorbidities like diabetes, tuberculosis, HIV were excluded from study this was the criteria for the study.Results: Out of 60 postoperative cases having perineal wounds, 35 (58.33%) patients opted for warm water seitz bath, while the rest 25 (41.66%) preferred regular room temperature seitz bath. In spite of a greater number of patients opting for warm seitz bath, wound recovery in terms of healing and wound discharge was almost similar in both the study groups. All the patients involved in the study were comfortable to resume their daily activities with significant reduction in pain by the end of first week irrespective of the choice of seitz bath they opted for.Conclusion: The study concludes that symptomatic relief and wound recovery in the operated cases of perineal surgeries completely independent of the choice of seitz bath practiced.

7.
Int. j. med. surg. sci. (Print) ; 7(2): 31-41, jun. 2020.
Article in English | LILACS | ID: biblio-1179269

ABSTRACT

Proper advice regarding home-based care of normal infants is no less important than managing critical diseases. Otherwise parents tend to follow traditional practices running in the family which are often deleterious. Clinicians must also be aware of the faulty traditional practices so that they can actively enquire them in the child's history.The author enlisted various such faulty traditional practices as experienced by him during his OPD practice in various public and corporate hospitals over a period of five years. Topics relating mainly to the infant age group have been chosen for this article. Relevant search was done on these topics in standard paediatric textbooks, journals, and websites (like WHO, NICE, AAP) to find the validity of these practices as well as the standard recommendations on these topics.It was found that the standard recommendations often differ from the traditional practices. Detailed text was included from various authentic sources regarding few dubious topics related to home-based infant care.Clinicians should be aware of the correct recommended methods regarding the day to day home-based infant care. They should counsel the parents accordingly so as to avoid any harm caused by faulty traditional practices and social beliefs.


El asesoramiento adecuado sobre la atención domiciliaria de los bebés normales no es menos importante que el manejo de enfermedades críticas. De lo contrario, los padres tienden a seguir las prácticas tradicionales de la familia que a menudo son perjudiciales. Los médicos también deben ser conscientes de las prácticas tradicionales defectuosas para poder investigarlas activamente en la historia del niño.El autor reclutó varias prácticas tradicionales defectuosas que experimentó durante su práctica en OPD en varios hospitales públicos y corporativos durante un período de cinco años. Para este artículo se han elegido temas relacionados principalmente con el grupo de edad infantil. Se realizaron búsquedas relevantes sobre estos temas en libros de texto, revistas y sitios web estándar de pediatría (como OMS, NICE, AAP) para encontrar la validez de estas prácticas, así como las recomendaciones estándar sobre estos temas.Se encontró que las recomendaciones estándar a menudo difieren de las prácticas tradicionales. Se incluyó texto detallado de varias fuentes auténticas con respecto a algunos temas dudosos relacionados con el cuidado infantil en el hogar.Los médicos deben conocer los métodos correctos recomendados con respecto al cuidado infantil diario en el hogar. Deben asesorar a los padres en consecuencia para evitar cualquier daño causado por prácticas tradicionales y creencias sociales defectuosas.


Subject(s)
Humans , Child, Preschool , Child , Child Care
8.
Article in Japanese | WPRIM | ID: wpr-873961

ABSTRACT

  Pregnancy has been removed from the list of contraindications for hot spring bathing. Therefore, The Japanese Society of Balneology, Climatology and Physical Medicine has considered that it is necessary to conduct a joint research on the safety of hot spring bathing for pregnant women, publish the results extensively, and enlighten the public about this matter. Considering that only a small number of reports have been published in Japan about the safety of hot spring bathing for pregnant women, the Society has decided to study this subject.   Expectant and nursing mothers living in hot spring towns, such as Beppu and Ibusuki City, have responded to questions about the period between the early stages of pregnancy and delivery via a self-administered questionnaire; The questions included: 1) age when the pregnancy ended, 2) number of previous deliveries, 3) details of hot spring bathing habits (whether they bathed in hot springs on a daily basis, how often they bathed during the different [early, middle, and late] stages of pregnancy, and whether they used hot spring baths attached to their homes or hot spring facilities away from their homes), and 4) whether they had pregnancy complications such as miscarriages (excluding those occurring in the early stages of pregnancy), premature delivery, threatened premature delivery, or toxemia of pregnancy/pregnancy-induced hypertension (edema, hypertension).  Total 1,721 responses were collected (86% reply rate). The mean participant age was 30.8 years. Importantly, there were 643 (37.6%) primigravid and 1,078 (62.4%) parous women. Age and gravidity were not associated with pregnancy complications. In the early and middle stages of pregnancy, there were no significant differences in the incidence of pregnancy complications between individuals who bathed ≥ once per week [hot spring bath (+)] group and those who bathed < once per week [hot spring bath (−)] group. In the late stages of pregnancy, the number of pregnancy complications were fewer in the hot spring bath (+) group (20.3%) than that in the hot spring bath (−) group (25.9%) (p = 0.028). In addition, there were no significant differences in the pregnancy complications between hot spring bathing (+) and hot spring bath (−) groups in the early and middle stages of pregnancy even if we focused on the homecoming pregnant women. Whereas, in the late stages of pregnancy, the number of pregnancy complications were fewer in the hot spring bath (+) group (13.0%) compared with the hot spring bath (−) group (24.5%) (p = 0.028) in the homecoming pregnant women.  This study has confirmed that daily hot spring bathing during pregnancy does not increase the incidence of pregnancy complications. Furthermore, it can be stated that the removal of “pregnancy” from the contraindications of hot spring bathing was appropriate.

9.
Article in Japanese | WPRIM | ID: wpr-873953

ABSTRACT

  A 53-year-old Japanese man living in Thailand who was diagnosed with prostate cancer was scheduled for a prostate biopsy due to increased serum PSA. Two days prior to his admission, he returned to Japan. The next day he was taken for pre-operative screening and blood tests, which revealed extremely high serum creatine kinase (CK) levels (13,631 IU/L). The following day, his serum CK increased to 29,836 IU/L with 100% type MM isozyme. In addition, his serum myoglobin was 3,289.0 ng/mL and his urinary myoglobin was 26,000 ng/mL. Based on these test results, the patient was diagnosed with rhabdomyolysis.  The patient revealed that he had gone to a public bath and bathed in an “electric bath” for a total of 90 min over the previous 2 days. During hospitalization, he remained asymptomatic and had no renal dysfunction. The prostate biopsy was performed as scheduled and he was given post-procedure care, including intravenous administration of saline. The patient’s serum CK peaked at 42,355 IU/L on the second day of hospitalization, and on the fifth day it decreased to 5,979 IU/L and he was discharged without any complications.   After a retrospective review of literature, only three reports were found mentioning an “electric bath”. Two of these reports were related to asymptomatic hyper-CK-emia caused by the electric bath, and one was a case related to the malfunction of an implantable cardioverter defibrillator due to an electric bath. The former two reports concluded that increased time in the electric bath was related to the observed increase in CK level. Since extended bathing in electric baths may cause rhabdomyolysis, further investigation is required to determine what duration of use is safe.

10.
Article in Japanese | WPRIM | ID: wpr-873952

ABSTRACT

  【Purpose】The number of deaths in the bathtub in the home is increasing year by year, of which about 90% are people over 65 years old. The purpose of this study was to verify the hypothesis that the effect on the circulatory dynamics would be less if one took a half-body bath first and then a whole- body bath after a certain period of time, rather than suddenly taking a whole- body bath.  【Methods】The subjects were ten healthy community elderly men (70.3 ± 4.0 years old). The subjects were bathed at 39°C and 41°C, respectively, with two immersion methods of a 6-min whole body bath and a 3 min whole-body bath after a 3 min half-bath (6 min total). Measured items were systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse (PR), oxygen saturation (SpO2), and forehead skin temperature. The subjective thermal sensation and comfort were also confirmed verbally. Measurements were carried out in the sitting posture before bathing, within 1 min after bathing, after 2 min, 3 min, and 5 min, just after the bath, and 5 min after sitting rest.   【Results】In both SBP (p = .010) and DBP (p = .019), the interaction between bathing conditions and measurement time was significant. SBP was greatly affected by temperature regardless of whether or not stepped immersion was used, and blood pressure decreased immediately after bathing at 41°C. DBP showed a significant decrease during bathing at 41°C compared with the whole-body bath after half-body bathing.  【Discussion】The SBP was markedly decreased immediately after taking a bath at a temperature of 41°C regardless of whether or not the subject was gradually immersed. It is thought that the condition is similar to that of orthostatic hypotension. Furthermore, DBP also showed a decrease of 10 mmHg or more, corresponding to changes during orthostatic hypotension, when bathing only with a whole-body bath at a temperature of 41°C. On the other hand, in the whole-body bath after half-body bathing, the decrease in DBP was less than 10 mmHg even at 41°C.

11.
Article in Japanese | WPRIM | ID: wpr-873950

ABSTRACT

  Using healthy volunteers, we examined the influence of emulsified oil and a low concentration of CO2 gas on cutaneous blood flow in the forearm. The forearm of each subject was immersed in 25 liters of warm water containing either 10 ppm emulsified oil or 60 ppm CO2 gas or both. Forearm cutaneous blood flow was measured for 20 minutes. Emulsified oil had no effect on cutaneous blood flow, whereas CO2 gas caused a gradual and significant increase. When CO2 gas was used with emulsified oil, cutaneous blood flow was significantly increased in comparison to CO2 alone, suggesting that emulsified oil enhances the vasodilation caused by CO2. We then prepared bath salts releasing CO2 and emulsified oil, and tested for their influence on sweating function in sixteen healthy adults. Each subject bathed daily 10 minutes either in tap water (control group) or in tap water dissolving bath salts releasing CO2 and emulsified oil (bath-salts group) at 40°C for successive 14 days. A sweating test was performed before and after the session of bathing. In the bath-salts group, the baseline tympanic temperature after successive bathing tended to be lower than that before successive bathing. Although the rise of body temperature during the heat exposure was not different between the groups, sweating rate was significantly greater after successive bathing. The analysis of the rate of sweat expulsion suggested that the greater sweat rate after the successive bathing is mediated by the central mechanism for sweating. Such changes were not observed in the control group. Thus, successive bathing using bath salts that release CO2 and emulsified oil may have a beneficial effect on sweating function.

12.
Article in Chinese | WPRIM | ID: wpr-873319

ABSTRACT

Fumigation (bath) therapy is widely used in clinic, but the methods are different. Based on the data mining of the existing clinical application of fumigation (bath) therapy, combined with the clinical application practice and relevant modern research, the technical specification (draft) of clinical application of traditional Chinese medicine (TCM) fumigation (bath) therapy has been formed after many demonstrations by experts from the external treatment branch. The specification (draft) includes indications, contraindications, pre-medication evaluation, pre-medication preparation, preparation of medicinal liquid, fumigation temperature, fumigation time, fumigation frequency, fumigation course, operation method, post-medication treatment and evaluation, matters needing attention, common adverse reactions and countermeasures, etc. The purpose of this paper is to standardize the clinical application of TCM fumigation (bath) therapy, improve its clinical curative effect and reduce adverse reactions.

13.
Article in Chinese | WPRIM | ID: wpr-847603

ABSTRACT

BACKGROUND: Medical ozone is a strong oxidant, can kill bacteria, resist inflammation, improve circulation, relieve pain and promote regeneration. It has been reported that medical ozone has a positive effect on ulcer wounds such as caries. OBJECTIVE: To explore the clinical effect of ozone bath on the control of diabetic foot ulcer’s infection and the promotion of wound healing. METHODS: According to the treatment methods, 100 patients with type 2 diabetic foot ulcer who met the inclusion criteria were divided into two groups randomly. In the experimental group, ozone bath was applied to the wound for 30 minutes after cleaning the wound with local normal saline; in the control group, air bath was applied to the wound for 30 minutes after cleaning the wound with local normal saline, once a day. Three weeks later, the bacterial control (quantitative analysis of bacteria, distribution of pathogenic bacteria), the degree of decline of inflammation index, the reduction of ulcer wound, the rate of wound healing and the visual analogue scale score of wound pain were counted in both groups. The expression levels of vascular endothelial growth factor, transforming growth factor-β and platelet-derived growth factor in wound tissues were measured before and after treatment. The protocols were approved by the Ethics Committee of Beijing Shijitan Hospital Affiliated to Capital Medical University. Patients and their family member signed the informed consent. RESULTS AND CONCLUSION: After 3 weeks of treatment, bacteria were still detected in 46 patients in the control group and 5 patients in the experimental group. The number of pathogenic bacteria was 73 before treatment and 66 after treatment in the control group, 74 before treatment and 7 after treatment in the experimental group. Bacterial quantitative analysis was significantly higher in the control group than in the experimental group after treatment. The indexes of ulcer healing, including the reduction of ulcer wound, the visual analogue scale score of wound pain, and the degree of decline of inflammation index, were better in the experimental group than those in the control group (P < 0.05). (4) The expression levels of vascular endothelial growth factor, transforming growth factor-β and platelet-derived growth factor in local wound tissues were significantly higher in the experimental group than in the control group (P < 0.05). The percentage of wound healing in the experimental group was significantly higher than that in the control group (P < 0.05). To conclude, ozone bath can significantly control the local infection of diabetic foot, reduce the distribution of pathogenic bacteria on the wound surface, relieve the inflammatory pain of the wound, stimulate the secretion of growth factor in wound, and improve the wound healing rate.

14.
Article in Chinese | WPRIM | ID: wpr-846557

ABSTRACT

Objective: To study the structural transformation pathway of indaconitine in stir-frying with sand process and compare the toxicity of indaconitine with its processing products. Methods: Using high performance liquid chromatography to screen out the temperature and time parameters of the structural transformation of indaconitine. The processing products were separated by column chromatography and identified by NMR and MS. The cardiotoxicity test was chosen to compare the toxicity of indaconitine with its processing products. Results: Indaconitine was converted into mithaconitine when it was heated at 160-180 ℃ for 10-30 min. With a dose of 0.06 mg/kg, indaconitine could induce ventricular arrhythmia in rats, such as ventricular premature beat, ventricular tachycardia. However, mithaconitine had no arrhythmogenic effect at the same dosage. Conclusion: The structural transformation pathway of indaconitine has been defined: deacetylating at C-8 position, generating 14-benzoylpseudaconine, and converting benzoylpseudaconine into mithaconitine by dehydration reaction at C-8 and C-15 position. Compared with indaconitine, the toxicity of mithaconitine was reduced.

15.
Rev. pesqui. cuid. fundam. (Online) ; 11(3): 627-633, abr.-maio 2019. tab
Article in English, Portuguese | LILACS, BDENF | ID: biblio-994777

ABSTRACT

Objective: The study's goal has been to assess the completion of the bed-bath procedure and the main care provided by the nursing team before, during and after it. Methods: It is a cross-sectional and observational study that was carried out in the Intensive Critical Unit of a teaching hospital with the participation of eight nurse technicians. Data collection was performed through an instrument structured type checklists over 30 times of observation from 1,080 actions. Results: There were observed 10 care before and 28 during and after bed-bath procedures. The bath was carried out technically without prior notice, without considering the individuality and privacy of patients, especially those undergoing mechanical ventilation. There was no participation of nurses and most of the actions taken by the nursing staff did not meet the literature recommendations. Conclusions: There is need to improving the quality of bed-bath procedures performed by the nursing team and adoption of evidence-based practices in the care process


Objetivo: Avaliar o processo de realização do banho no leito e os cuidados realizados pela equipe de enfermagem antes, durante e após o banho no leito. Métodos: estudo transversal e observacional, realizado na Unidade de Terapia Intensiva de um Hospital/Escola, com oito técnicos de enfermagem. Para a coleta de dados foi utilizado instrumento estruturado tipo checklists em 30 momentos de observação de 1080 ações. Resultados: foram observados 10 cuidados antes e 28 durante e após o banho no leito. O banho foi realizado de forma automática sem comunicação prévia, sem considerar a individualidade e privacidade do paciente, principalmente naqueles submetidos a ventilação mecânica. Não houve participação do enfermeiro e a maioria das ações realizadas pela equipe de enfermagem não atendeu às recomendações da literatura. Conclusões: há necessidade de melhoria da qualidade do banho no leito realizado pela enfermagem e adoção de práticas baseadas em evidências no processo de cuidar


Objetivo: Evaluar el proceso de finalización del baño de la cama y los principales cuidados que proporciona el personal de enfermería antes, durante y después del baño en la cama. Métodos: Transversal, observacional realizado en la UCI de un hospital / escuela con ocho técnicos de enfermería. Para la recolección de datos se utilizó instrumento de tipo estructurado listas de control 30 veces observación de 1080 la acción. Resultados: en el 10 y 28 de atención médica antes durante y después del baño en la cama. El baño se llevó a cabo técnicamente sin previo aviso, sin tener en cuenta la individualidad y la privacidad de los pacientes, especialmente aquellos sometidos a ventilación mecánica. No hubo participación de las enfermeras y la mayoría de las acciones llevadas a cabo por el personal de enfermería no cumplía con las recomendaciones de la literatura. Conclusiones: Existe la necesidad de mejorar la calidad de baño de la cama llevada a cabo por la enfermería y la adopción de prácticas basadas en la evidencia en el proceso de atención


Subject(s)
Humans , Male , Female , Baths/nursing , Baths/standards , Licensed Practical Nurses/education , Intensive Care Units , Hygiene/standards , Critical Care Nursing , Nursing Care
16.
Braz. dent. sci ; 22(3): 305-312, 2019. tab, ilus
Article in English | LILACS, BBO | ID: biblio-1008364

ABSTRACT

Objective: The aim of the study was to evaluate the influence of different surface post-etching treatments in flexural strength, contact angle and surface roughness of a lithium disilicate ceramic. Material and Methods: 60 bars (16 x 2 x 4 mm) were divided in six groups (n=10): C, no treatment; HF, hydrofluoric acid for 20 s (HF) + washing (60 s), drying (30s); HFL, HF + washing (60 s), drying (30 s) and luting; HFNL, HF + washing (60 s) + neutralization with sodium bicarbonate (SB) for 40 s + washing (5s), drying (30 s) and luting; HFUL, HF + washing (60 s) + ultrasonic bath (UB) for 4 min, drying (30 s) and luting; HFNUL, HF + washing (60 s) + SB (40 s) + UB (4 min) and luting. The bars were submitted to three-points flexural strength test. 25 ceramic blocks (12 x 7 x 7 mm) were divided into five groups (n=5) to evaluate roughness and contact angle C - no treatment; HF - HF ; HFU - HF and UB for 5 min ; HFN - HF and SB; HFNU - HF, UB and SB. A scanning electron microscope (SEM) showed the surface of the samples. ANOVA one-way statistical analysis was done for comparison of results. Results: There was no statistical difference for flexural strength (p-value = 0.15) and for surface roughness (p-valor = 0.15). However, it was obtained statistically significant difference for contact angle (p-valor = 0.00). SEM images showed precipitates after the acid etching, which were removed by post-etching treatments. Conclusion: It can be concluded that the different post-etching surface treatments did not increase the flexural strength, surface roughness, but it influenced the ceramic wetting and SEM images (AU)


Objetivo: O objetivo do estudo foi avaliar a influência de diferentes tratamentos pós-condicionamento na resistência à flexão, ângulo de contato e rugosidade superficial de uma cerâmica de dissilicato de lítio. Material e Métodos: 60 barras (16 x 2 x 4 mm) foram divididas em seis grupos (n = 10): C, sem tratamento; HF, ácido fluorídrico durante 20 s (HF) + lavagem (60 s), secagem (30 s); HFL, lavagem com HF + (60 s), secagem (30 s) e cimentação; HFNL, HF + lavagem (60 s) + neutralização com bicarbonato de sódio (SB) por 40 s + lavagem (5s), secagem (30 s) e cimentação; HFUL, HF + lavagem (60 s) + banho ultrassônico (UB) por 4 min, secagem (30 s) e cimentação; HFNUL, HF + lavagem (60 s) + SB (40 s) + UB (4 min) e cimentação. As barras foram submetidas ao teste de resistência à flexão de três pontos. 25 blocos cerâmicos (12 x 7 x 7 mm) foram divididos em cinco grupos (n = 5) para avaliação da rugosidade superficial e ângulo de contato C - sem tratamento; HF - HF; HFU - HF e UB por 5 min; HFN - HF e SB; HFNU - HF, UB e SB. Um microscópio eletrônico de varredura (MEV) foi utilizado para análise da superfície das amostras. A análise estatística unidirecional ANOVA-um fator foi realizada para comparação dos resultados. Resultados: Não houve diferença estatística para a resistência à flexão (p-valor = 0,15) e para a rugosidade superficial (p-valor = 0,15). No entanto, obteve-se diferença estatisticamente significante para o ângulo de contato (p-valor = 0,00). Imagens de microscopia eletrônica de varredura mostraram a formação de precipitados após o ataque ácido, que foram removidos pelos tratamentos pós-condicionamento. Conclusão: Pode-se concluir que os diferentes tratamentos de superfície pós-condicionamento não aumentaram a resistência à flexão, rugosidade da superfície, mas influenciaram na molhabilidade da cerâmica e nas imagens em MEV.(AU)


Subject(s)
Electron Microscope Tomography , Hydrofluoric Acid
17.
Article in Chinese | WPRIM | ID: wpr-803543

ABSTRACT

Objective@#To investigate the application of clohexidine wipes in patients after liver transplantation and the effect of infection prevention.@*Methods@#A total of 279 patients who received orthotopic liver transplantation in the first affiliated hospital of sun yat-sen university from January 2017 to December 2018 and were transferred to the intensive care department of our hospital after the surgery were selected as subjects. Among them, 145 patients who received liver transplantation between January and December 2017 were selected as the control group. From January to December, 2018, 134 patients after liver transplantation were enrolled as the intervention group, and were treated with clohexidine 2% gluconate wet wipes, and the hospital infection rate, infection rate, multiple drug-resistant bacteria infection rate, bath time consumption, and adverse reaction rate were compared between the two groups.@*Results@#The hospital infection rate of the control group was 20.00% (29/145), the infection rate of patients was 37.93%(55/145), the infection rate of multiple drug-resistant bacteria was 25.52%(37/145), and the infection rate of the intervention group was 11.19% (15/134), 24.63% (33/134), 14.93% (20/134). The differences were statistically significant (χ2=4.065, 5.709, 4.806, P<0.05). The bath time of the control group was (16.70±1.42) minutes, and the intervention group was (14.07±1.53) minutes. Compared with the control group, the bath time of the intervention group was saved, and the difference was statistically significant (t=9.637, P<0.01).No discomfort symptoms such as disinfectant allergy were found in both groups.@*Conclusion@#The application of clohexidine 2% gluconate wet wipes in the wiping bath of patients after liver transplantation had a good effect, significantly reducing the hospital infection rate, saving the time of wiping bath.

18.
Article in Chinese | WPRIM | ID: wpr-802514

ABSTRACT

With the rapid rise of modern drug-derived diseases, the external treatment has received extensive attention at home and abroad, due to its small adverse reactions, convenient application and accurate efficacy.At present, although there are many clinical applications of Chinese medicine external treatment, there are few unified norms and strong arbitrariness in related external treatment techniques, for example, external methods, dosage forms, means, dosage, time, etc.As a result, the development of Chinese medicine external treatment is slow and chaotic, and it can not serve the clinic well.It also hinders the development and expansion of external treatment techniques.This paper discusses the current status of external treatment techniques, and clarifies the development trend of Chinese medicine external treatment, in order to pointing out the direction for the development of Chinese medicine external treatment, it will promote the standardization of Chinese medicine external treatment techniques, and it will be better servicing the clinical practice.

19.
Article in Chinese | WPRIM | ID: wpr-801536

ABSTRACT

Objective@#To observe the effect of modified Gualou-Guizhi decoction combined with hyperbaric oxygen on muscle tension and motor function in stroke patients with spastic hemiplegia.@*Methods@#A total of 70 stroke patients with spastic hemiplegia met the inclusion criteria were randomly divided into the observation group and the control group, with 35 in each group. The control group was given the conventional treatment and hyperbaric oxygen treatment, while the observation group was treated with Gualou-Guizhi decoction on the basis of the control group. Lindmark scale was used to assess limb motor function, Fugl-Meyer Assessment Scale (FMA) was used to assess the degree of limb motor dysfunction, and Modified Ashworth Scale (MAS) was used to assess muscle tension. The root mean square (RMS) and frequency median (FM) of surface electromyography of quadriceps femoris were measured by automatic electromyography, and the clinical efficacy was evaluate.@*Results@#The total effective rate of the observation group was 91.4% (32/35), and the total effective rate of the control group was 71.4% (25/35). The total effective rate of the 2 groups was statistically significant (χ2=4.629, P=0.0314). After treatment, the scores of motor coordination ability and sensory function in the observation group were significantly higher than those in the control group (t value were 5.936, 5.182, all Ps<0.05), the FMA scores of upper and lower limbs were significantly higher than those in the control group (t value were 12.310, 11.996, all Ps<0.01), and the score of improved Ashworth muscle strength scale was significantly lower than that in the control group (t=5.083, P=0.031). After treatment, the EMG RMS (79.13 ± 7.02 vs. 68.45 ± 7.01 , t=5.697), FM (99.31 ± 9.65 Hz vs. 90.73 ± 9.49 Hz, t=5.382) of the observation group were significantly higher than those of the control group (P<0.05).@*Conclusions@#The application of Gualou-Guizhi decoction add and subtract combined with hyperbaric oxygen on muscle tension and motor function in stroke patients with spastic hemiplegia can improve the muscle strength of stroke hemiplegic patients and improve the motor dysfunction of the patients, which can help to promote the recovery of the movement function of the patientst.

20.
Article in English | WPRIM | ID: wpr-785358

ABSTRACT

BACKGROUND: Dry sauna has been very popular as an alternative therapy for promoting health among people who want to improve their health condition without relying on pharmaceuticals. The aim of this study was to investigate whether dry sauna therapy improved quality of life and reduced pain in participants with low back pain.METHODS: Study participants comprised a total of 37 consecutive patients who were over 20 years of age with low back pain. Dry sauna therapy was performed twice per day for 5 consecutive days over the course of 1 week, thus comprising a total of 10 sessions each of 15 min of exposure to a 90℃ dry sauna.RESULTS: The verbal numerical rating scale (VNRS) and Oswestry disability index (ODI) scores were significantly reduced after dry sauna therapy (P < 0.001 for both). VNRS pain scores had a median (range) of 5 (2–8) before dry sauna therapy and 3 (0–8) after dry sauna therapy. ODI scores had a median (range) of 12 (2–24) before dry sauna therapy and 8 (1–17) after dry sauna therapy. The proportion of participants who reported successful treatment (excellent + good) was 70%. No adverse effects were observed related to dry sauna therapy.CONCLUSIONS: Our results suggest that dry sauna therapy may be useful to improve quality of life and reduce pain in patients with low back pain. Therefore, pain physicians can recommend dry sauna therapy as an alternative and complimentary therapy for patients with low back pain.


Subject(s)
Humans , Low Back Pain , Quality of Life , Steam Bath
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