ABSTRACT
ObjectiveTo explore the correlation between blood stasis constitution （BSC） and diseases based on constitution literature involving “constitution-diseases correlation”. MethodsA comprehensive search was conducted on six Chinese and English electronic databases including CNKI， Wanfang， VIP， SinoMed， PubMed and Embase to find all clinical researches on the correlation between constitution and diseases using the Classification and Identification of Chinese Medicine Constitution standard from April 1st， 2009 to December 31st， 2022， and the participants of the research were BSC related. By analyzing the characteristics of the literature， such as authors， publication institutes， participants， and results， the disease with the highest proportion of BSC distribution or BSC as their risk factors or protective factors were summarized to explore the correlation between BSC and diseases. ResultsTotally 135 clinical studies on diseases highly related to BSC were included， with a total sample size of 71 172 cases.There were 27 keywords in the articles appeared more than 3 times， including the elderly， lumbar disc herniation， coronary heart disease， cardiovascular disease， and endometriosis. In the author's clustering， included studis were mainly from Shenzhen Hospital of Beijing University of Chinese Medicine， Second Affiliated Hospital of Guangzhou University of Chinese Medicine， and Wenzhou Central Hospital. In terms of blood stasis related diseases， 81 studies showed that BSC was the most common type of constitution in the study population， involving 48 disease or morbid states. The diseases and median proportions of BSC with reported literature ≥3 included coronary heart disease （28.8%）， endometriosis （31.3%）， neurocognitive impairment （26.4%）， lumbar disc herniation （26.0%）， ischemic stroke （25.0%）， adenomyosis （34.7%）， and endometrial polyps （25.0%）. Fifty-eight studies found that BSC was a risk factor for disease occurrence，and these diseases reported more than 3 times included hypertension （median OR = 2.956）， type 2 diabetes （median OR = 3.436），osteoporosis （median OR = 5.171）， sudden deafness （median OR = 3.827） and endometriosis （median OR = 5.412）. One study indicated BSC as the protective factor of lateral growth tumor of large intestine （median OR = 0.161）. ConclusionBSC is closely related to circulatory system diseases， urogenital system diseases， and musculoskeletal system diseases.
ABSTRACT
Objective To investigate the physical health of female college students with various types of traditional Chinese medicine(TCM) constitution. Methods The physical health state of 608 female college students was evaluated by National Student Physical Health Standards issued by Ministry of Education and by TCM Constitution Questionnaire. And then the data were analyzed by regression analysis. Results(1)A total of 608 questionnares was issued, and 600 were responded,with an effective response rate being 100%. (2)TCM constitution types of the 600 female college students were classified into harmony constitution(208 cases), damp-heat constitution(180 cases),yin deficiency constitution(78 cases),Qi stagnation constitution(51 cases), Qi deficiency constitution (36 cases), yang deficiency constitution (31 cases), blood-stasis constitution(9 cases),phlegm-dampness constitution (7 cases),and specific constitution (none). (3)Of the 9 constitution types, the physical health of the female college students with harmony constitution was the best, with an excellent rate being 59.61% and the rate for pass and being good arriving to 39.90%. And the pass rate almost arrived to 100%. Of the 8 bias constitution types,the physical health of the female college students with blood-stasis constitution was the worst, with a failed rate of 88.89%, and then came the Qi stagnation constitution, with a failed rate of 74.51%. (4)With the 9 constitution types as the independent variables, and with the excellent grade(≥86 scores),pass and good grade(60-85 scores),failed grade(≤59 scores)respectively as the dependent variables, harmony constitution and damp-heat constitution were included into the model of Forward stepwise regression analysis for the excellent grade, yang deficiency constitution, yin deficiency constitution and phlegm-dampness constitution were included into the model of Forward stepwise regression analysis for the pass and good grade,and Qi stagnation constitution and blood-stasis constitution were included into the model of Forward stepwise regression analysis for the failed grade. Conclusion Harmony constitution is the dominant constitution type in female college students,and the physical health of the harmony constitution is the best. The scores of physical health vary in the students with different constitution types. TCM constitution has certain dialectical relations with National Student Physical Health Standards.
ABSTRACT
Objective To explore the characteristics of constitution according to traditional Chinese medicine and the anxiety susceptibility of the population, providing the theoretical basis for carrying out population intervention in anxiety and taking full advantage of the preventive treatment by investigating anxiety emotion of patients. Methods A cross-sectional study method was adopted. 317 anxiety patients were recruited into an observation group and another 251 anxiety patients were recruited into a control group. Based on the traditional Chinese medicine constitution scale we defined every participant’s constitution type and got the distribution of different constitution types among all the participants. Then we usedχ2 test and binary regression to analyze the impact of constitution on anxiety. Result The observation group constitution type distribution:Qi stagnation(19.24%), Qi deficiency(16.40%), blood stasis(15.46%), damp heat (11.04%), Yang deficiency(10.41%), Yin deficiency(8.83%), phlegm dampness(6.62%), mild quality(5.99%), special intrinsic quality(5.99%). The control group constitution type distribution:damp heat(17.53%), Yin deficiency (14.34%), phlegm dampness (13.94%), Yang deficiency(11.55%),mild quality (11.55%), Qi stagnation (8.76%), Qi deficiency (8.37%), blood stasis (7.97%), special intrinsic quality (5.98%). The result ofχ2 test showed that the distribution of constitution types among participants in the observation group were different from that in the control group and the difference was statistically significant(P0.05). The binary regression result showed that the three constitutions of Qi stagnation, Qi deficiency and blood stasis had significantly positive correlation with anxiety(P<0.05). Odds ratios showed Exp of Qi stagnation, Qi deficiency and blood stasis was 4.447, 3.942 and 3.929. while the other six constitutions are independent factors to anxiety. Conclusion Qi stagnation, Qi deficiency and blood stasis constitutions were possible risk factors for anxiety.