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Arch. endocrinol. metab. (Online) ; 67(3): 427-441, June 2023. tab, graf
Article in English | LILACS-Express | LILACS | ID: biblio-1429752


ABSTRACT Congenital adrenal hyperplasia due to 21-hydroxylase deficiency is an autosomal recessive disorder caused by CYP21A2 gene mutations, and its molecular diagnosis is widely used in clinical practice to confirm the hormonal diagnosis. Hence, considering the miscegenation of the Brazilian population, it is important to determine a mutations panel to optimise the molecular diagnosis. The objective was to review the CYP21A2 mutations' distribution among Brazilian regions.Two reviewers screened Brazilian papers up to February 2020 in five databases. The pair-wise comparison test and Holm method were used in the statistical analysis. Nine studies were selected, comprising 769 patients from all regions. Low proportion of males and salt-wasters was identified in the North and Northeast regions, although without significant difference. Large gene rearrangements also had a low frequency, except in the Center-West and South regions (p < 0.05). The most frequent mutations were p.I172N, IVS2-13A/C>G, p.V281L and p.Q318X, and significant differences in their distributions were found: p.V281L was more frequent in the Southeast and p.Q318X in the Center-West and Northeast regions (p < 0.05). Thirteen new mutations were identified in 3.8%-15.2% of alleles, being more prevalent in the North region, and six mutations presented a founder effect gene. Genotype-phenotype correlation varied from 75.9%-97.3% among regions. The low prevalence of the salt-wasting form, affected males and severe mutations in some regions indicated pitfalls in the clinical diagnosis. The good genotype-phenotype correlation confirms the usefulness of molecular diagnosis; however, the Brazilian population also presents significant prevalence of novel mutations, which should be considered for a molecular panel.

Arch. endocrinol. metab. (Online) ; 67(3): 348-354, June 2023. tab
Article in English | LILACS-Express | LILACS | ID: biblio-1429754


ABSTRACT Objective: Follicular thyroid carcinoma (FTC) is less frequent but has a worse prognosis than papillary carcinoma. The available evidence on pre-operative characteristics of FTC is controversial. Our objective was to characterize the clinical, ultrasound and histopathological presentation of FTC patients treated Chile. Subjects and methods: Retrospective analysis of 97 patients treated for FTC in 6 large centers in Chile. We analyzed their ultrasonographic features and classified the nodules according to ATA risk of malignancy and TI-RADS score, as well as the cytological findings according to the Bethesda system. We described their clinical and histopathological findings at diagnosis and classified their risk of recurrence and mortality according to ATA 2015 recurrence risk category and the eighth edition of the AJCC/UICC staging system, respectively. Results: Median age was 48 years and 73.2% were females. The median diameter was 38.8 mm; only 9.5% of them were microtumors. According to ATA risk of malignancy, 86% of the nodules were low or intermediate suspicious, while 78% were category 3 or 4A nodules according to the TI-RADS. Regarding the Bethesda system, 65.9% had indeterminate cytology (20.6% category III and 45.3% category IV). At histological examination, most were minimally-invasive and angio-invasive tumors with less than 4 foci (54.7% and 28.4% respectively). More than 90% of FTC were unifocal and there was no lymphovascular or extrathyroidal invasion or lymph node involvement. Four patients (4.1%) had distant metastases at diagnosis. Most patients (95%) had stage I or II disease according to the AJCC/UICC staging system, while the risk of recurrence was low at 51.5% when using the ATA risk of recurrence scale. Conclusions: At diagnosis, most FTCs were nodules of low or intermediate suspicion at ultrasound, nearly two thirds had indeterminate cytology according to the Bethesda system, and nearly 50% of them were of low risk of recurrence.

Estud. pesqui. psicol. (Impr.) ; 23(1): 250-269, maio 2023.
Article in English, Spanish, Portuguese | LILACS-Express | LILACS | ID: biblio-1434527


O estudo teve como objetivo conhecer as experiências de mães e médicos em relação ao comunicado do diagnóstico da síndrome de Down (SD). Trata-se de uma pesquisa exploratória e transversal, com delineamento qualitativo. Participaram 9 mães e 7 médicos. Foram realizadas 16 entrevistas semiestruturadas individuais. Os dados foram transcritos e submetidos à análise de conteúdo temática. Constatou-se que, para mães e médicos, é uma experiência complexa e difícil, permeada por sentimentos ambivalentes. Nas mães, predominam a tristeza, medo e angústia. A maioria delas sentiram-se insatisfeitas na maneira como receberam o diagnóstico, isso foi atribuído por elas e pelos médicos à falta de preparo durante a formação profissional. Conclui-se que algumas sugestões podem nortear a comunicação do diagnóstico, no intuito de favorecer a elaboração do mesmo, a saber: respeitar o tempo para a mãe observar e conhecer o bebê antes de receber o diagnóstico, comunicar a mãe com sensibilidade e empatia, preferencialmente na presença do outro genitor e de um psicólogo, procurar dar ênfase aos aspectos positivos da saúde do bebê.

The study aimed to know the experiences of mothers and doctors in relation to the statement of the Down syndrome (DS) diagnosis. This is a exploratory and transversal research, with a qualitative design. 9 mothers and 7 doctors participated. 16 individual semi-structured interviews were carried out. The data were transcribed and submitted to thematic content analysis. It was found that for mothers and doctors, it is a complex and difficult experience, permeated by ambivalent feelings. In mothers, sadness, fear and anguish predominate. Most of them felt dissatisfied in the way as they received the diagnosis, this was attributed by them and the doctors to the lack of preparation during vocational training. It is concluded that, some suggestions can guide the communication of the diagnosis, in order to favor its elaboration, namely: respect the time for the mother to observe and get to know the baby before receiving the diagnosis, communicate it to the mother with sensitivity and empathy, preferably in the presence of the other parent and a psychologist, try to emphasize the positive aspects of the baby's health.

El estudio tuvo como objetivo conocer las experiencias de madres y médicos en relación al comunicado del diagnóstico del síndrome de Down (SD). Se trata de una investigación exploratoria y transversal, con delineamiento cualitativo. Participaron 9 madres y 7 médicos. Se realizaron 16 entrevistas semiestructuradas individuales. Los datos fueron transcritos y sometidos al análisis de contenido temático. Se constató que, para madres y médicos, es una experiencia compleja y difícil, impregnada de sentimientos ambivalentes. En las madres predominan la tristeza, el miedo y la angustia. La mayoría de ellas se sintieron insatisfechas en la forma en que recibieron el diagnóstico, eso fue atribuido por ellas y por los médicos a la falta de preparación durante la formación profesional. Se concluye que algunas sugerencias pueden guiar la comunicación del diagnóstico, con el fin de favorecer la elaboración del mismo, a saber: respetar el tiempo para la madre observar y conocer al bebé antes de recibir el diagnóstico, comunicar la madre con sensibilidad y empatía, preferiblemente en presencia del otro progenitor y de un psicólogo, buscar dar énfasis a los aspectos positivos de la salud del bebé.

Medicina (B.Aires) ; 83(1): 29-34, abr. 2023. graf
Article in English | LILACS-Express | LILACS | ID: biblio-1430769


Abstract Introduction: The purposes of our study were to describe the distribution of diagnoses in a series of 273 patients over 65 years of age who presented for neck masses and to identify semiological fea tures associated with malignancy. Methods: Neck masses were categorized as congenital lesions (n = 7, 3%, 95% CI: 1%- 5%), inflammatory masses (n = 67, 25%, 95% CI: 19%- 30%), benign neoplasms (n = 77, 28%, 95% CI: 23%- 34%), and malignant neoplasms (n = 87, 32%, 95% CI: 26%- 38%). Results: A group of patients had discontinued care and, consequently, a definitive diagnosis could not be reached (n = 35, 12%). Age (OR 1.06, 95% CI 1.00-1.12), male sex (OR 2.35, 95% CI 1.11-4.96), prior history of cancer (OR 2.66, 95% CI 1.02-6.92), mass fixation to skin or deep tissues (OR 4.87, 95% CI 2.20-10.76), and the involvement of multiple cervical lymph node levels (OR 4.15, 95% CI 1.64-10.51) were identified as semiological features associated with malignancy. Conclusion: In the case of a neck mass in an elderly patient, its neoplastic origin should be strongly suspected.

Resumen Introducción: El objetivo de nuestro estudio fue describir la distribución de diagnósticos en una serie de 273 pacientes mayores de 65 años que consultaron por masas cervicales e identificar características semiológicas asociadas a malignidad. Métodos: Las masas cervicales fueron categorizadas como lesiones congénitas (n = 7, 3%, 95% CI: 1%- 5%), masas de origen inflamatorio (n = 67, 25%, 95% CI: 19%-30%), neoplasias benignas (n = 77, 28%, 95% CI: 23%- 34%) y neoplasias malignas (n = 87, 32%, 95% CI: 26%-38%). Resultados: Un grupo de pacientes discontinuó el tratamiento y en consecuencia no fue posible alcanzar un diagnóstico defini tivo (n = 35, 12%). La edad (OR 1.06, 95% CI 1.00-1.12), el sexo masculino (OR 2.35, 95% CI 1.11-4.96), los antecedentes de cáncer (OR 2.66, 95% CI 1.02-6.92), la fijación de la masa a los planos profundos o a piel (OR 4.87, 95% CI 2.20-10.76) y la afectación de más de un nivel ganglionar del cuello (OR 4.15, 95% CI 1.64-10.51) fueron identificados como características semiológicas asociadas a malignidad. Conclusión: En presencia de una masa cervical en un paciente adulto mayor debe existir una fuerte sospecha de origen neoplásico.

Medicina (B.Aires) ; 83(1): 133-137, abr. 2023. graf
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1430783


Resumen La infección por coronavirus (SARS-CoV-2/COVID-19) es responsable de un diverso rango de manifestaciones extrapulmonares entre las cuales se destaca el compromiso neurológico directo o indirecto. La apoplejía hipofisaria es una entidad médica y neuroquirúrgica de gravedad variable que suele asociarse a la presencia de un adenoma subyacente. Un escaso número de reportes han vinculado estas dos enfermedades entre sí. Este trabajo describe un caso de apoplejía hipofisaria manifestada clínicamente en for ma concomitante al diagnóstico de COVID 19, en un paciente con macroadenoma hipofisario desconocido y su manejo terapéutico, revisando los mecanismos potencialmente subyacentes al nexo entre ambas entidades.

Abstract Coronavirus disease (SARS-CoV-2/COVID-19) is responsible for a wide variety of extrapulmonary manifestations, among which direct or indirect neurological compromise stands out. Pituitary apoplexy is a clinical and neurosurgical entity of variable severity, usually associated with a pituitary adenoma. Literature is scarce regarding the association between these diseases. This paper reports a case of pituitary apoplexy, manifested concomitantly to the diagnosis of COVID 19 in a patient with unknown pituitary macroadenoma, and its therapeutic management, reviewing the mechanisms potentially underlying the link between both entities.

Acta neurol. colomb ; 39(1): 51-56, ene.-mar. 2023.
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1429574


RESUMEN INTRODUCCIÓN: El diagnóstico oportuno del trastorno neurocognitivo es de los principales retos en la atención de los trastornos neurocognitivos. Por esto, se han generado estrategias para la detección preclínica de la enfermedad, entre ellas las destinadas a evaluar síntomas neuropsiquiátricos (NPS) como la escala Mild Behavior Impairment - Checklist (MBI-C). MÉTODOS: Inicialmente se realizó una búsqueda en BVSalud, Medline y PsycNet, luego se realizó una búsqueda en bola de nieve. Se incluyeron términos referentes a deterioro comportamental leve (abarcando los NPS en etapas tempranas), deterioro cognitivo leve y términos específicos del MBI-C. RESULTADOS: La presencia de NPS se asocia con un aumento en la incidencia anual de demencia. Al evaluarlos con MBI-C, su puntuación se correlaciona con biomarcadores como una mayor atrofia cortical, la presencia de la proteína β-amiloide, así como disminución en funciones ejecutivas como la capacidad de enfocar la atención y la memoria de trabajo. DISCUSIÓN: Los hallazgos en la literatura sugieren la utilidad de MBI-C como marcador de neurodegeneración en estadios previos a la demencia, esto mediante la evaluación de su capacidad predictiva de forma independiente y al compararla con otros biomarcadores. CONCLUSIONES: MBI-C supone ser un instrumento de fácil aplicabilidad e interpretación, sostenible e incluyente. Sin embargo, quedan vacíos sobre la pertinencia de esta escala, por lo que surge la necesidad de investigar este tema.

ABSTRACT INTRODUCTION: Early diagnosis of neurocognitive disorder is the main challenge of dementia health attention. Therefore, strategies for preclinical detection of the disease have been created, like those intended to evaluate neuropsychiatric symptoms (NPS), like the Mild Behavior Impairment - Checklist (MBI-C). METHODS: Research was performed in BVSalud, Medline, and Psynet. Then a snowball sampling was done. The terms included were mild behavioral impairment (included NPS in initial stages), mild cognitive impairment, and specific terms of MBI-C. RESULTS: The presence of NPS increase the incidence of dementia, with an annual conversion rate of 9%. About MBI-C, the score has been related to biomarkers like worse brain atrophy in patients with Parkinson's Disease and a positive relationship with the presence of B-amyloid protein. Also, Creese and cols. show that mild behavioral impairment (measured by MBI-C) is associated with a faster decrease in attention and working memory. DISCUSSION: MBI-C utility as a neurodegenerative marker has been demonstrated to detect cognitive, neuropsychiatry, and functional symptoms that may precede dementia by evaluating its predictive capacity alone and comparing it to other biomarkers. CONCLUSION: MBI-C is easy to apply and interpret, is sustainable and inclusive. However, there are still gaps in the relevance of the scale, so there is the need to continue investigating this topic.

Arch. cardiol. Méx ; 93(1): 37-43, ene.-mar. 2023. tab, graf
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1429703


Resumen Introducción: Las cardiopatías congénitas son los trastornos congénitos más frecuentes en la población mundial, se manifiestan generalmente después del nacimiento. Las altitudes entre 2,500 y 3,500 metros sobre el nivel del mar se han relacionado con la alta incidencia de cardiopatías congénitas como el ductus arterioso persistente, los defectos del septum auricular y los defectos del septum ventricular. Objetivo: Caracterizar clínica y sociodemográficamente los pacientes con diagnóstico de cardiopatías congénitas procedentes de altitudes bajas, moderadas y altas en un hospital regional de Colombia. Metodología: Estudio observacional, descriptivo retrospectivo. Se incluyeron todos los pacientes menores de 18 años con diagnóstico de cardiopatías congénitas, atendidos en el Hospital Universitario San Rafael de Tunja entre el 2015 y 2021. Resultados: El 51.9% de los pacientes eran de sexo masculino, el 16.3% tenían antecedente de prematurez y el 9.1% tenían diagnóstico de síndrome de Down. Las cardiopatías más frecuentes fueron: ductus arterioso persistente (35.1%), seguido de comunicación interventricular (21.6%) y comunicación intrauricular (19.7%). Conclusiones: Se deben establecer estrategias como el tamizaje y diagnóstico oportuno de las cardiopatías congénitas en poblaciones de riesgo con el fin de mejorar el pronóstico de vida de los pacientes y desenlace de la enfermedad.

Abstract Introduction: Congenital heart diseases are the most common congenital disorders in the world population, they generally manifest after birth. Altitudes between 2,500-3,500 meters above sea level have been linked to the high incidence of congenital heart diseases such as patent ductus arteriosus, atrial septum defects, and ventricular septum defects. Objetives: To characterize clinically and sociodemographically the patients diagnosed with congenital heart disease from low, moderate and high altitudes in a regional hospital in Colombia. Methodology: Observational, descriptive retrospective study. All patients under 18 years of age with a diagnosis of congenital heart disease, treated at the San Rafael de Tunja University Hospital between 2015 and 2021, were included. Results: 51.9% of the patients were male, 16.3% had a history of prematurity and 9.1% had a diagnosis of Down syndrome. The most frequent heart diseases were: persistent ductus arteriosus 35.1%, followed by ventricular communication representing 21.6% and intra-atrial communication with 19.7%). Conclusions: They must eestablish strategies such as screening and timely diagnosis of congenital heart disease in at-risk populations in order to improve the life prognosis of patients and the outcome of the disease.

Enferm. foco (Brasília) ; 14: 1-7, mar. 20, 2023. graf
Article in Portuguese | LILACS, BDENF | ID: biblio-1433714


Objetivo: Descrever diagnósticos de Enfermagem baseados nos discursos de mulheres sobre a repercussão do câncer mamário e mastectomia. Métodos: Trata-se de pesquisa descritiva, com abordagem qualitativa, realizada em uma Organização Não Governamental (ONG) no município de João Pessoa, Paraíba, Brasil. O universo amostral foi composto por todas as 15 mulheres mastectomizadas durante os meses de setembro e outubro de 2017. Essas mulheres responderam um roteiro de entrevista semiestruturada. A análise dos dados qualitativos foi norteada pela Técnica de Análise de Conteúdo proposta por Bardin. Após a delimitação das categorias, foram construídos diagnósticos de Enfermagem por meio da Classificação Internacional da Prática de Enfermagem (CIPE)®. Resultados: Foram identificadas três categorias temáticas: Sentimentos experenciados após diagnóstico de câncer e realização da mastectomia; Modificações biológicas e psicológicas após a mastectomia; Resiliência diante do sofrimento. Os diagnósticos de Enfermagem elencados foram: angústia, bem-estar prejudicado, bem-estar espiritual prejudicado, autoestima alterada, autoimagem alterada, capacidade de autocuidado prejudicada, dificuldades diárias, distúrbio da identidade pessoal, insatisfação com a vida e o corpo. Conclusão: é necessário enfatizar o cuidado no momento de verbalizar o diagnóstico, a escuta diante do outro e a percepção das mulheres diante do processo de adoecimento. (AU)

Objective: To describe nursing diagnoses based on women's discourse on the repercussions of breast cancer and mastectomy. Methods: This is a descriptive research, with a qualitative approach, carried out in a Non-Governmental Organization (NGO) in the city of João Pessoa, Paraíba, Brazil. The sample universe was composed of all 15 women undergoing mastectomy during the months of September and October 2017. These women answered a semi-structured interview script. The analysis of qualitative data was guided by the Content Analysis Technique proposed by Bardin. After delimiting the categories, Nursing diagnoses were constructed using the International Classification of Nursing Practice (ICNP) ®. Results: Three thematic categories were identified: Feelings experienced after cancer diagnosis and mastectomy; Biological and psychological changes after mastectomy; Resilience in the face of suffering. The nursing diagnoses listed were anguish, impaired well-being, impaired spiritual well-being, impaired self-esteem, impaired self-image, impaired self-care capacity, daily difficulties, personal identity disorder, dissatisfaction with life and body. Conclusion: it is necessary to emphasize care when verbalizing the diagnosis, listening to the other and the women's perception of the illness process. (AU)

Objetivo: Describir los diagnósticos de enfermería basados en el discurso de las mujeres sobre las repercusiones del cáncer de mama y la mastectomía. Métodos: Se trata de una investigación descriptiva, con enfoque cualitativo, realizada en una Organización No Gubernamental (ONG) en la ciudad de João Pessoa, Paraíba, Brasil. El universo muestral estuvo compuesto por las 15 mujeres sometidas a mastectomía durante los meses de septiembre y octubre de 2017. Estas mujeres respondieron un guión de entrevista semiestructurado. El análisis de datos cualitativos fue guiado por la Técnica de Análisis de Contenido propuesta por Bardin. Después de delimitar las categorías, los diagnósticos de enfermería se construyeron utilizando la Clasificación Internacional de la Práctica de Enfermería (CIPE) ®. Resultados: Se identificaron tres categorías temáticas: sentimientos experimentados después del diagnóstico de cáncer y mastectomía; Cambios biológicos y psicológicos después de la mastectomía; Resiliencia ante el sufrimiento. Los diagnósticos de enfermería enumerados fueron angustia, deterioro del bienestar, deterioro del bienestar espiritual, deterioro de la autoestima, deterioro de la autoimagen, deterioro de la capacidad de autocuidado, dificultades diarias, trastorno de la identidad personal, insatisfacción con la vida y el cuerpo. Conclusion: es necesario enfatizar el cuidado al verbalizar el diagnóstico, escuchar al otro y la percepción de la mujer sobre el proceso de la enfermedad. (AU)

Breast Neoplasms , Nursing Diagnosis , Mastectomy
Hematol., Transfus. Cell Ther. (Impr.) ; 45(1): 52-57, Jan.-Mar. 2023. tab, graf
Article in English | LILACS | ID: biblio-1421550


Abstract Introduction During pregnancy, women are at an increased risk of developing iron-deficiency anemia. Objective The objective of this study was to assess the diagnostic performance of the reticulocyte hemoglobin equivalent (RET-He) in the early detection of iron-deficiency anemia in a group of pregnant women and to establish a reference range for this parameter in a group of control individuals. Method: A total of 60 patients and 130 control subjects were included in the study. Blood samples collected from the subjects were submitted to a complete blood count and a serum ferritin test and the data were analyzed by comparing the groups and ROC curves. Results The reference range found for the RET-He was between 29.75pg and 38.24pg, with a median of 35pg. The receiver operating characteristic (ROC) curve analysis for the ferritin parameter showed an area under the curve of 0.732 for the RET-He, 0.586 for hemoglobin, 0.551 for the mean corpuscular hemoglobin concentration and 0.482 for the mean corpuscular volume. Conclusion Early diagnosis of iron deficiency anemia in pregnancy is essential to prevent damage to both maternal and fetal health. The RET-He presents an excellent potential as an auxiliary tool for the diagnosis of iron deficiency in pregnant women.

Humans , Female , Pregnancy , Adolescent , Adult , Middle Aged , Aged , Young Adult , Pregnancy , Iron Deficiencies , Reticulocytes , Hemoglobins , Anemia, Iron-Deficiency , Hematology
Rev. colomb. cir ; 38(2): 289-299, 20230303. tab, fig
Article in Spanish | LILACS | ID: biblio-1425202


Introducción. La fuga anastomótica es la complicación más grave del tratamiento quirúrgico del cáncer de colon por su alta morbimortalidad. El diagnóstico evidente, manifestado por la salida de contenido intestinal por drenajes o la herida quirúrgica, ocurre tardíamente (entre el 6º y 8º día). El objetivo de este trabajo fue estudiar la variación de los valores de la proteína C reactiva postoperatoria para hacer un diagnóstico precoz. Métodos. Estudio observacional, analítico, retrospectivo, de una cohorte de pacientes con neoplasia, en quienes se realizó cirugía oncológica con anastomosis intestinal, entre enero de 2019 y diciembre de 2021. Se midieron los valores en sangre de proteína C reactiva postoperatoria (1°, 3° y 5° días). Resultados. Se compararon 225 casos operados que no presentaron fuga con 45 casos con fuga. En los casos sin fuga, el valor de proteína C reactiva al 3º día fue de 148 mg/l y al 5º día de 71 mg/l, mientras en los casos con fuga, los valores fueron de 228,24 mg/l y 228,04 mg/l, respectivamente (p<0,05). Para un valor de 197 mg/l al 3º día la sensibilidad fue de 77 % y para un valor de 120 mg/l al 5º día la sensibilidad fue de 84 %. Conclusión. El mejor resultado de proteína C reactiva postoperatoria para detectar precozmente la fuga anastomótica se observó al 5º día. El valor de 127 mg/l tuvo la mejor sensibilidad, especificidad y valor predictivo negativo, lo cual permitiría el diagnóstico temprano y manejo oportuno de esta complicación

Introduction. Anastomotic leak is the most serious complication of surgical treatment of colon cancer due to its high morbidity and mortality. The obvious diagnosis manifested by the exit of intestinal content through drains or the operative wound, occurs late (between the 6th and 8th day). The objective of this work was to study the postoperative C-reactive protein values to make an early diagnosis. Methods. Observational, analytical, retrospective study of a cohort of patients undergoing colorectal surgery for neoplasia, between January 2019 and December 2021, who underwent oncological surgery with intestinal anastomosis and measured CRP blood values on 1st, 3rd and 5th post-operative days. Results. Two-hundred-twenty-five operated cases that did not present leaks were compared with 45 cases with leaks, with CRP values on the 3rd and 5th day of 148mg/l and 71mg/l in cases without leakage and CRP values of 228.24mg/l and 228.04 mg/l in cases with leakage on the 3rd and 5th day, respectively (p<0.05), CRP value of 197mg/l on the 3rd day has a sensitivity of 77%; CRP value of 120mg/l on the 5th day, has a sensitivity of 84%. Conclusions. The best result for CPR to early diagnosis of anastomotic leak was observed on the 5th day, having the value of 127 mg/l the best sensitivity, specificity and NPV, which would allow early diagnosis and timely management

Humans , C-Reactive Protein , Early Diagnosis , Anastomotic Leak , Postoperative Complications , Anastomosis, Surgical , Colorectal Neoplasms
Enferm. foco (Brasília) ; 14: 1-6, mar. 20, 2023. tab
Article in Portuguese | LILACS, BDENF | ID: biblio-1425437


Objetivo: Apresentar as características clínicas dos pacientes vítimas de trauma que necessitaram de transfusão emergencial para uma abordagem do Diagnóstico de Enfermagem "Risco de Choque"; descrever a atuação da equipe de Enfermeiros do Trauma nesse contexto. Métodos: Trata-se de um estudo descritivo, retrospectivo, de abordagem quantitativa. Os dados retratam o período de outubro de 2018 a dezembro de 2019, perfazendo um total de 447 pacientes com choque hemorrágico por trauma inseridos no Protocolo de Transfusão Maciça de um hospital público. Resultados: O "Risco de Choque" foi o diagnóstico de enfermagem prioritário nos pacientes com hemorragia grave por trauma. Houve predominância do sexo masculino, vítimas de politraumatismo em sua maioria, com idade entre 18 e 29 anos. 197 pacientes apresentaram líquido livre que foi detectado através do exame de ultrassom de emergência nos pacientes com trauma torácico ou abdominal. O Serviço de Atendimento Móvel de Urgência foi o meio utilizado por 378 pacientes para atendimento pré-hospitalar. Conclusão: A caracterização mostra a gravidade desses casos, com necessidade de transfusão maciça. O conhecimento desses fatores pela equipe multiprofissional de pacientes críticos com hemorragia grave associada ao trauma é fundamental, tornando-se necessária a abordagem do diagnóstico de enfermagem "risco de choque" pelo profissional Enfermeiro. (AU)

Objective: To present the clinical characteristics of the trauma patients who required emergency transfusion for an approach to the Nursing Diagnosis "Risk of Shock"; describe the role of the Trauma Nurses team in this context. Methods: This is a descriptive, retrospective study with a quantitative approach. The data portrays the period from October 2018 to December 2019, making up a total of 447 patients with traumatic hemorrhagic shock inserted in the Mass Transfusion Protocol of a public hospital. Results: There was a predominance of male subjects, victims polytrauma in that majority, aged between 18 and 29 years old. 197 patients had free fluid that was detected by emergency ultrasound examination in patients with chest or abdominal trauma. The Mobile Emergency Care Service was the resource used by 378 patients to the pre-hospital care. Conclusion: The characterization shows the severity of these cases, requiring massive transfusion. The knowledge of these factors by the multidisciplinary team of critically ill patients with severe hemorrhage associated with trauma is essential, making it necessary for the nursing professional to approach the nursing diagnosis "risk of shock". (AU)

Objetivo: Presentar las características clínicas de los pacientes traumatizados que requirieron transfusión urgente para el abordaje del Diagnóstico de Enfermería "Riesgo de Choque"; describir el papel del equipo de enfermeras de trauma en este contexto. Métodos: Se trata de un estudio descriptivo, retrospectivo con enfoque cuantitativo. Los datos retratan el período de octubre de 2018 a diciembre de 2019, lo que hace un total de 447 pacientes con choque hemorrágico traumático insertado en el Protocolo de Transfusión Masiva de un hospital público. Resultados: El "Riesgo de Choque" fue el diagnóstico de enfermería prioritario en los pacientes con hemorragia por trauma severo. Predominó el sexo masculino, mayoritariamente víctimas de politraumatismos, con edades comprendidas entre los 18 y 29 años. 197 pacientes tenían líquido libre que fue detectado por el examen de ultrasonido de emergencia con traumatismo torácico o abdominal. El Servicio Móvil de Atención de Emergencias fue el medio utilizado por 378 pacientes para la atención prehospitalaria. Conclusión: La caracterización muestra la gravedad de estos casos, requiriendo transfusión masiva. El conocimiento de estos factores por parte del equipo multidisciplinario de pacientes críticos con hemorragia severa asociada a trauma es fundamental, por lo que es necesario que el profesional de enfermería aborde el diagnóstico de enfermería "riesgo de shock". (AU)

Multiple Trauma , Shock, Hemorrhagic , Nursing Diagnosis
Bol. méd. Hosp. Infant. Méx ; 80(1): 53-56, Jan.-Feb. 2023. graf
Article in English | LILACS-Express | LILACS | ID: biblio-1429940


Abstract Background: Vascular malformations (VaM) are a heterogeneous group of disorders resulting from the dysmorphogenesis of blood vessels. Although correct classification is relevant to providing adequate treatment according to evidence-based medicine, diagnostic terminology may be misused or need clarification. Methods: We conducted a retrospective study to measure agreement and concordance between referral and final confirmed diagnoses of 435 pediatric patients with VaM newly referred to the multidisciplinary Vascular Anomalies Clinic (VAC) using Fleiss kappa (κ) concordance analysis. Results: We found fair concordance between referral and confirmed diagnoses of VaM (κ 0.306, p < 0.001). Lymphatic malformations (LM) and VaM associated with other anomalies showed moderate diagnostic concordance (κ 0.593, p < 0.001 and κ 0.469, p < 0.001, respectively). Conclusions: Continuing medical education strategies are required to improve physician knowledge and diagnostic accuracy in patients with VaM.

Resumen Introducción: Las malformaciones vasculares (MVa) son un grupo heterogéneo de trastornos resultantes de la dismorfogénesis de los vasos sanguíneos. A pesar de que la correcta clasificación es relevante para brindar un adecuado tratamiento de acuerdo con la medicina basada en la evidencia, la terminología diagnóstica podría resultar confusa o utilizarse de manera inapropiada. Métodos: En este estudio retrospectivo se midieron el acuerdo y la concordancia entre los diagnósticos de referencia (o derivación) y los diagnósticos finales confirmados de 435 pacientes pediátricos con MVa recién remitidos a la Clínica de anomalías vasculares (CAV) multidisciplinaria, mediante el análisis de concordancia kappa de Fleiss (κ). Resultados: Se encontró una buena concordancia entre los diagnósticos de referencia (o derivación) y los diagnósticos confirmados de MVa (κ 0.306, p < 0.001). Las malformaciones linfáticas (LM) y las MVa asociadas con otras anomalías presentaron concordancias diagnósticas moderadas (κ 0.593, p < 0.001 y κ 0.469, p < 0.001, respectivamente). Conclusiones: Se requiere de estrategias de educación médica continua para mejorar el conocimiento de los médicos y la precisión diagnóstica de los pacientes con MVa.

Int. j. morphol ; 41(1)feb. 2023.
Article in English | LILACS-Express | LILACS | ID: biblio-1430513


SUMMARY: Digit ratio established in utero is positivelly correlated with intrauterine level of estrogen. Since the breast cancer is related to excessive and prolonged exposure to estrogen, digit ratio might be considered as useful marker in breast cancer risk assessment. The aim of the present study was to compare digit ratios in breast cancer patients and healthy controls. The study group consisted of 98 breast cancer patients aged between 29 to 84 years while the control group included 141 healthy women aged between 21 and 67 years. After collecting anamnestic data concerning menopausal status, the length of second and fourth fingers were measured and the digit ratios were calculated for both hands, as well as the difference between right and left digit ratio. Digit ratio was significantly higher on right hand in breast cancer patients compaired to healthy controls (1.003±0.05 vs. 0.990±0.03). Right digit ratio showed better predictive capacity for the breast cancer development then the left (AUC:0.609 vs. 0.541). Negative statistically significant correlation between right digit ratio and the age of breast cancer diagnosis was observed (r=-0.271). Higher values of right digit ratio in women with breast cancer when compared to healthy women suggest their higher prenatal estrogen exposure that confirms the importance of digit ratio determination in breast cancer risk assessment.

La proporción de dígitos establecida en el útero, se correlaciona positivamente con el nivel intrauterino de estrógeno. Dado que el cáncer de mama está relacionado con una exposición excesiva y prolongada a los estrógenos, la proporción de dígitos podría considerarse un marcador útil en la evaluación del riesgo de cáncer de mama. El objetivo del presente estudio fue comparar proporciones de dígitos en pacientes con cáncer de mama y controles sanos. El grupo de estudio consistió en 98 pacientes con cáncer de mama con edades comprendidas entre los 29 y los 84 años, mientras que el grupo de control incluyó a 141 mujeres sanas con edades comprendidas entre los 21 y los 67 años. Después de recopilar datos anamnésticos sobre el estado menopáusico, se midió la longitud de los dedos segundo y anular y se calcularon las proporciones de los dedos para ambas manos, así como la diferencia entre la proporción de los dedos derecho e izquierdo. La proporción de dígitos fue significativamente mayor en la mano derecha en pacientes con cáncer de mama en comparación con controles sanos (1,003 ± 0,05 frente a 0,990 ± 0,03). La proporción del dígito derecho mostró una mejor capacidad predictiva para el desarrollo de cáncer de mama que el izquierdo (AUC: 0.609 vs. 0.541). Se observó una correlación estadísticamente significativa negativa entre la proporción de dígitos derechos y la edad del diagnóstico de cáncer de mama (r=-0,271). Los valores más altos de la proporción de dígitos derechos en mujeres con cáncer de mama en comparación con mujeres sanas sugieren una mayor exposición prenatal a estrógenos que confirma la importancia de la determinación de la proporción de dígitos en la evaluación del riesgo de cáncer de mama.

Medwave ; 23(1): e2648, 28-02-2023.
Article in English, Spanish | LILACS-Express | LILACS | ID: biblio-1419219


Los trastornos temporomandibulares son complejos trastornos multisistémicos para los que, lamentablemente, siguen prevaleciendo los enfoques tradicionales odontocéntricos comunes de la investigación y la atención. Un comité designado por las Academias Nacionales de Ciencias, Ingeniería y Medicina de los Estados Unidos de América resumió importantes recomendaciones relativas a la urgente necesidad de transformar, desde el modelo predominantemente biomédico, la investigación, la educación/formación profesional y la atención al paciente para los trastornos temporomandibulares en el modelo biopsicosocial que es estándar en el resto de la medicina del dolor. La publicación del informe del estudio de consenso identifica once recomendaciones de corto y largo plazo respecto a brechas y oportunidades orientadas a la situación en Estados Unidos, que son igualmente aplicables a la situación en Chile. Las primeras cuatro recomendaciones se centran en la investigación básica y traslacional, la investigación en salud pública y el fortalecimiento de la investigación clínica. Las tres recomendaciones siguientes se refieren a la evaluación de riesgos, el diagnóstico y la difusión de guías de práctica clínica y métricas asistenciales para mejorar la atención de los pacientes y ampliar su acceso. Las recomendaciones octavas a décima proponen centros de excelencia para el tratamiento de los trastornos temporomandibulares y el dolor orofacial, la mejora de la formación en los centros profesionales y la ampliación de la formación continua especializada para los profesionales sanitarios. La undécima recomendación se centra en la educación de los pacientes y la reducción del estigma. Este artículo destaca las recomendaciones publicadas y aborda lo que debiesen considerar los profesionales chilenos, como primer paso hacia un gran esfuerzo por cambiar los paradigmas de investigación, tratamiento y educación sobre los trastornos temporomandibulares para los próximos años.

Temporomandibular disorders (TMDs) are complex multi-system disorders for which common traditional dental-centric approaches to research and care unfortunately continue to prevail. A committee appointed by the National Academies of Sciences, Engineering and Medicine (NAM) of the United States of America summarized important recommendations regarding the urgent need to transform, from the predominantly biomedical model, the research, professional education/training, and patient care for TMDs into the biopsychosocial model that is standard in the rest of pain medicine. The release of the Consensus Study Report identifies eleven short-term and long-term recommendations regarding gaps and opportunities oriented towards the situation in the US, which are equally applicable to the situation in Chile. The first four recommendations focus on basic and translational research, public health research and strengthening clinical research. The next three recommendations concern risk assessment, diagnostics, and dissemination of clinical practice guidelines and care metrics to improve patient care and expand its access. Recommendations eight to ten propose Centers of Excellence for Temporomandibular Disorders and Orofacial Pain Treatment, improving professional school education, and expanding specialized continuing education for healthcare providers. The eleventh recommendation focuses on patient education and stigma reduction. This article highlights the published recommendations and addresses what should be considered by Chilean professionals, as a first step of a major effort to shift TMD research, treatment, and education paradigms for the years to come.

Arq. bras. oftalmol ; 86(1): 74-78, Jan.-Feb. 2023. graf
Article in English | LILACS | ID: biblio-1403474


ABSTRACT We describe the case of a 15-year-old girl with decreased visual acuity associated with elevated intraocular pressure in both eyes and angle closure on gonioscopy. She also presented attenuation of retinal vessels and optic disc pallor with large excavation in the left eye. Ultrasound biomicroscopy revealed an anteriorly positioned ciliary body and absence of ciliary sulcus, confirming the plateau iris configuration. Spectral-domain optical coherence tomography revealed a bilateral cystoid macular edema. Genetic screening revealed heterozygous variants of the Crumbs homolog 1 (CRB1) gene (c.2843G>A and c.2506C>A). The patient underwent trabeculectomy for intraocular pressure control and topical treatment for macular edema. This case highlights the importance of performing gonioscopy and evaluating intraocular pressure in patients with a shallow anterior chamber despite young age. In addition, it also shows the importance of genetic screening, when available, in elucidating the diagnosis and providing patients and their families' information on the patient's prognosis and possible therapeutic options.

RESUMO Nós descrevemos um caso de uma paciente de 15 anos com queda de acuidade visual e aumento da pressão intraocular em ambos os olhos, juntamente com fechamento angular no exame de gonioscopia. Na fundoscopia a paciente apresentava atenuação dos vasos retinianos, palidez de disco e aumento de escavação em olho esquerdo. Ao exame da biomicroscopia ultrassônica, foi evidenciado corpo ciliar anteriorizado e ausência de sulco ciliar em ambos os olhos, relevando presença de íris em plateau. Ao exame de tomografia de coerência óptica, visualizamos presença de edema macular cistoide bilateral. O screening genético revelou heterozigose no gene CRB1 (c.2843G>A and c.2506C>A), confirmando o diagnóstico de retinose pigmentar. Este caso reforça a importância do exame de gonioscopia e da avaliação da pressão intraocular em pacientes em câmara rasa, mesmo em pacientes jovens. Além disso, mostra a importância do screening genético como ferramenta útil para elucidação diagnóstica.

Humans , Adolescent , Glaucoma, Angle-Closure , Retinitis Pigmentosa , Glaucoma, Angle-Closure/surgery , Glaucoma, Angle-Closure/genetics , Retinitis Pigmentosa/complications , Retinitis Pigmentosa/genetics , Eye Proteins/genetics , Membrane Proteins , Nerve Tissue Proteins
Rev. Flum. Odontol. (Online) ; 1(60): 23-29, jan.-abr. 2023.
Article in Portuguese | LILACS, BBO | ID: biblio-1411182


A inteligência artificial é proveniente do setor de informática e consta de tecnologia com mecanismo oriundo de softwares, que é capaz de propiciar benefícios por intermédio do recurso da sua utilização em todos campos da sociedade. No setor saúde seu emprego tem se mostrado satisfatório, inclusive na área odontológica. No geral, na área da saúde pode-se aperfeiçoar e aprimorar a abordagem realizada preventivamente, uma vez que se pode proferir diagnósticos precocemente, obtendo melhor desfecho para os tratamentos. O objetivo do presente artigo foi investigar como o emprego da inteligência artificial pode agir e auxiliar no transcorrer dos procedimentos odontológicos. Os diagnósticos precoces são requisitados também a nível odontológico, almejando com essa aparatologia minimizar eventuais falhas nos tratamentos. Em âmbito odontológico pode-se dispor desse recurso nas áreas de Diagnóstico Bucal, Ortodontia, Dentística e Radiologia Odontológica. Concluiu-se que com o uso da inteligência artificial pode-se obter melhor desfecho nos tratamentos odontológicos realizados, concomitantemente sendo viável a racionalização do tempo gasto nos tratamentos e uma melhor confortabilidade aos pacientes e aos cirurgiões dentistas que estão em atendimento.

Artificial intelligence comes from the information technology sector and consists of technology with a mechanism derived from software, which is capable of providing benefits through the resource of its use in all fields of society. In the health sector, its use has been satisfactory, including in the dental field. In general, in the health area, the approach carried out preventively can be improved and improved, since diagnoses can be made early, obtaining a better outcome for the treatments. The objective of this article was to investigate how the use of artificial intelligence can act and help in the course of dental procedures. Early diagnoses are also required at the dental level, aiming with this apparatus to minimize eventual failures in treatments. In the dental field, this resource can be made available in the areas of Oral Diagnosis, Orthodontics, Dentistry and Dental Radiology. It was concluded that with the use of artificial intelligence, a better outcome can be obtained in the dental treatments performed, concomitantly being viable the rationalization of the time spent in the treatments and a better comfort to the patients and to the dentists who are in attendance.

Artificial Intelligence , Oral Health , Dentistry , Early Diagnosis
Arq. neuropsiquiatr ; 81(1): 47-54, Jan. 2023. tab, graf
Article in English | LILACS-Express | LILACS | ID: biblio-1429881


Abstract Background Reliable instruments that lead to early diagnosis for CP are extremely important so that these children are referred for early stimulation, benefiting their development. Objective To perform a cross-cultural adaptation and reliability assessment of a Brazilian version of the Hammersmith Neonatal Neurological Examination (HNNE), expanded and summarized. Methods A methodological, cross-sectional, nonexperimental quantitative analysis was conducted in two phases as follows: cultural adaptation of the HNNE, expanded and summarized, and reliability assessment of the Brazilian version of the HNNE. Phase one was developed in five stages (initial translation, synthesis of the translation, a committee of experts, backtranslation, and submission to the author), with the semantic questions, content, and face validity being evaluated. Phase two included 143 newborns and we analyzed the internal consistency, stability, and equivalence (intra- and interexaminer) of the instrument. Internal consistency was calculated using Cronbach's alpha, and intra- and interexaminer reliability and reproducibility assessed through test-retest were calculated using the intraclass correlation coefficient Results Although internal consistency, assessed using Cronbach's alpha, showed unsatisfactory results, the results of inter-and intraexaminer equivalence showed a high agreement between the evaluations in all domains. The test-retest also showed excellent agreement between the domains. Conclusions The Brazilian HNNE expanded and summarized versions can be considered to be adapted and reliable for the neurological assessment of Brazilian newborns to identify changes in neurological development and early referral to the stimulation or early rehabilitation units and as a promising option to be used in the context of primary care in Brazil.

Resumo Antecedentes As avaliações neurológicas que levam ao diagnóstico precoce permitem o acesso oportuno à intervenção em um período em que os maiores ganhos são possíveis devido à neuroplasticidade. Objetivos Realizar a adaptação transcultural e avaliação da confiabilidade da versão brasileira do Hammersmith Neonatal Neurological Examination (HNNE), ampliada e resumida. Métodos Foi realizada análise quantitativa metodológica, transversal e não experimental em duas fases: adaptação cultural do HNNE, ampliada e resumida, e avaliação da confiabilidade da versão brasileira do HNNE. A primeira fase foi desenvolvida em cinco etapas (tradução inicial, síntese da tradução, comitê de especialistas, retrotradução e submissão ao autor), sendo avaliadas as questões semânticas, conteúdo e validade de face. A fase dois incluiu 143 recém-nascidos e foram analisadas a consistência interna, estabilidade e equivalência (intra e interexaminador) do instrumento. A consistência interna foi calculada pelo alfa de Cronbach, e a confiabilidade e reprodutibilidade intra e interexaminadores avaliadas por meio do teste-reteste foram calculadas pelo coeficiente de correlação intraclasse. Resultados Embora a consistência interna, avaliada pelo alfa de Cronbach, tenha apresentado resultados insatisfatórios, os resultados da equivalência inter e intraexaminadores mostraram alta concordância entre as avaliações em todos os domínios. O teste-reteste também apresentou excelente concordância entre os domínios. Conclusões As versões brasileiras ampliadas e resumidas do HNNE podem ser consideradas adaptadas e confiáveis para avaliação neurológica de recém-nascidos brasileiros por identificar alterações no desenvolvimento neurológico e encaminhamento precoce para unidades de estimulação ou reabilitação precoce e como uma opção promissora para uso no contexto da atenção básica no Brasil.

Arq. neuropsiquiatr ; 81(1): 81-94, Jan. 2023. tab
Article in English | LILACS-Express | LILACS | ID: biblio-1429889


Abstract In the last few decades, there have been considerable improvements in the diagnosis and care of Duchenne muscular dystrophy (DMD), the most common childhood muscular dystrophy. International guidelines have been published and recently reviewed. A group of Brazilian experts has developed a standard of care based on a literature review with evidence-based graded recommendations in a two-part publication. Implementing best practice management has helped change the natural history of this chronic progressive disorder, in which the life expectancy for children of the male sex in the past used to be very limited. Since the previous publication, diagnosis, steroid treatment, rehabilitation, and systemic care have gained more significant insights with new original work in certain fields. Furthermore, the development of new drugs is ongoing, and some interventions have been approved for use in certain countries. Therefore, we have identified the need to review the previous care recommendations for Brazilian patients with DMD. Our objective was to create an evidence-based document that is an update on our previous consensus on those topics.

Resumo Nas últimas décadas, houve progressos significativos no diagnóstico e no tratamento da distrofia muscular de Duchenne (DMD), considerada a distrofia muscular mais comum na infância. Diretrizes internacionais foram publicadas e revisadas recentemente. Um grupo de especialistas brasileiros desenvolveu um padrão de atendimento baseado em revisão de literatura, com recomendações graduadas pautadas em evidências compiladas em uma publicação dividida em duas partes. A implementação de melhores práticas de manejo ajudou a modificar a história natural desta doença crônica, progressiva, que, no passado, oferecia uma expectativa de vida muito limitada para crianças do sexo masculino. Desde a publicação desse consenso anterior, o diagnóstico, o tratamento com esteroides, a reabilitação e os cuidados sistêmicos ganharam novas possibilidades a partir da divulgação dos resultados de trabalhos originais em algumas dessas áreas. Além disso, as pesquisas e o desenvolvimento de novos fármacos estão em andamento, e algumas intervenções já foram aprovadas para uso em determinados países. Nesse contexto, identificamos a necessidade de rever as recomendações anteriores sobre o manejo dos pacientes brasileiros com DMD. Nosso objetivo principal foi elaborar uma atualização baseada em evidências sobre esses tópicos do consenso.

Article in Portuguese | LILACS, INDEXPSI | ID: biblio-1418579


Este artigo de revisão sistemática analisou produções e pesquisas científicas a respeito de práticas escolares que fazem uso de laudos e diagnósticos no contexto da inclusão escolar no Brasil, no período de 2009 a 2019, objetivando acessar as contingências desse uso enquanto um dispositivo de (ex)inclusão. Para tanto, foi realizada busca no Portal Periódicos CAPES, utilizando os descritores "diagnóstico" and "educação especial", "diagnóstico" and "inclusão escolar", "laudo" and "educação especial" e "laudo" and "inclusão escolar", o que resultou em 261 artigos submetidos à Revisão por Pares. Após aplicação de critérios de inclusão e exclusão, obteve-se a amostra final de 13 artigos, publicados em 8 periódicos, com predominância das regiões Sul e Centro-Oeste, e equilíbrio entre estudos teóricos e empíricos. De um modo geral, os estudos apresentam dois tipos de posicionamentos a respeito do uso de laudos e diagnósticos nas práticas de inclusão: reconhecem efeitos patologizantes e limitantes; mas também identificam situações em que laudos e diagnósticos se fazem necessários. As práticas tematizadas dão pistas de que a inclusão como educação para todos se impõe ainda como um desafio a educadores e pesquisadores da área

This systematic review article analyzed scientific production and research on school practices that make use of reports and diagnoses in the context of school inclusion in Brazil, in the period from 2009 to 2019, aiming to access the contingencies of this use as a device of (ex)inclusion. To this end, a search was conducted in the CAPES Portal Periódicos, using the descriptors "diagnosis" and "special education", "diagnosis" and "school inclusion", "report" and "special education" and "report" and "school inclusion", which resulted in 261 articles submitted to Peer Review. After applying inclusion and exclusion criteria, a final sample of 13 articles was obtained, published in 8 journals, with predominance of the South and Midwest regions, and balance between theoretical and empirical studies. In general, the studies present two types of positions regarding the use of reports and diagnoses in inclusion practices: they recognize pathologizing and limiting effects; but they also identify situations in which reports and diagnoses are necessary. The practices discussed give clues that inclusion as education for all is still a challenge to educators and researchers in the field.

Education, Special , Mainstreaming, Education
Arq. ciências saúde UNIPAR ; 27(3): 1377-1387, 2023.
Article in Portuguese | LILACS-Express | LILACS | ID: biblio-1426507


O estilo de vida sedentário envolve um gasto energético similar aos valores basais em repouso, sendo prejudicial à saúde. Dessa forma, o presente estudo objetiva sintetizar o conhecimento produzido sobre indicadores clínicos, fatores causais e relações clínicas entre os indicadores e os fatores causais do diagnóstico de enfermagem estilo de vida sedentário em estudantes universitários. Trata-se de uma revisão integrativa da literatura, realizada no mês de novembro de 2022. As fontes de dados consultadas foram: Scopus Content Overview, Cumulative Index to Nursing and Allied Health Literature, PubMed e Web of Science. A amostra foi composta por dez artigos. Em relação aos estudos incluídos, todos eram internacionais, publicados em sua maioria no ano de 2021 (30%) e escritos na língua inglesa (90%). O principal indicador clínico encontrado foi atividade física menor que a recomendada. Quanto aos fatores causais, encontrou-se tempo de tela excessivo, tempo de atividade física insuficiente, falta de tempo para se exercitar, tempo sentado prolongado, atividades sedentárias educacionais e socialização sedentária. As relações clínicas encontradas foram excesso de adiposidade, sono prejudicado e saúde mental prejudicada. Conclui-se que a literatura referente aos indicadores clínicos, fatores causais e relações clínicas do diagnóstico estudado é limitada, necessitando de pesquisas que possam preencher as lacunas de conhecimento.

The sedentary lifestyle involves an energy expenditure similar to the basal values at rest, being harmful to health. Thus, this study aims to synthesize the knowledge produced on clinical indicators, causal factors, and clinical relationships between the indicators and causal factors of the nursing diagnosis sedentary lifestyle in college students. This is an integrative literature review, conducted in November 2022. The data sources consulted were: Scopus Content Overview, Cumulative Index to Nursing and Allied Health Literature, PubMed, and Web of Science. The sample was composed of ten articles. Regarding the studies included, all were international, published mostly in the year 2021 (30%) and written in English (90%). The main clinical indicator found was physical activity lower than recommended. As for causal factors, excessive screen time, insufficient physical activity time, lack of time to exercise, prolonged sitting time, sedentary educational activities, and sedentary socialization were found. The clinical relationships found were excessive adiposity, impaired sleep, and impaired mental health. It is concluded that the literature regarding the clinical indicators, causal factors, and clinical relationships of the diagnosis studied is limited, necessitating research that can fill the gaps in knowledge.

El sedentarismo implica un gasto energético similar a los valores basales en reposo, siendo perjudicial para la salud. Por lo tanto, este estudio tiene como objetivo sintetizar los conocimientos producidos sobre los indicadores clínicos, factores causales y las relaciones clínicas entre los indicadores y factores causales del diagnóstico de enfermería estilo de vida sedentario en estudiantes universitarios. Se trata de una revisión bibliográfica integradora, realizada en noviembre de 2022. Las fuentes de datos consultadas fueron: Scopus Content Overview, Cumulative Index to Nursing and Allied Health Literature, PubMed y Web of Science. La muestra estuvo compuesta por diez artículos. En cuanto a los estudios incluidos, todos eran internacionales, publicados en su mayoría en el año 2021 (30%) y escritos en inglés (90%). El principal indicador clínico encontrado fue una actividad física inferior a la recomendada. En cuanto a los factores causales, se encontraron el tiempo excesivo frente a la pantalla, el tiempo insuficiente de actividad física, la falta de tiempo para hacer ejercicio, el tiempo prolongado sentado, las actividades educativas sedentarias y la socialización sedentaria. Las relaciones clínicas encontradas fueron la adiposidad excesiva, la alteración del sueño y la alteración de la salud mental. Se concluye que la literatura relativa a los indicadores clínicos, factores causales y relaciones clínicas del diagnóstico estudiado es limitada, siendo necesaria la realización de investigaciones que puedan colmar las lagunas de conocimiento.