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Article in Chinese | WPRIM | ID: wpr-879171


Metallomics is a frontier interdisciplinary subject at its vigorous development stage. Its goal is to systematically study the content, distribution, chemical species, structural characteristics and functions of metal elements in biological system. It is also a comprehensive discipline to study the existing state and function of free or complex metal elements in life. Metallomics is an ideal tool to study the biological behavior of inorganic elements, which can be used to solve many problems in the research of mineral Chinese medicine(MCM). It provides a strong theoretical basis and technical support for the research of MCM. Its theory and methods provide re-ference and enlightenment for the in-depth study of MCM, and also provide new ideas and open up new ways for the research of MCM. The application of metallomics theory and methods in the research of MCM is of great significance to reveal the material basis and mec-hanism of MCM, promote the process of basic research on MCM, fully exploit and utilize medicinal mineral resources and carry forward the traditional MCM treasure in China. In this paper, we introduced the concept, academic development, research content and research methods of metallomics, and discussed the application prospects of metallomics in the analysis of inorganic element composition characteristics and quality control, material basis and mechanism of MCM, so as to provide reference for further researches on MCM.

China , Drugs, Chinese Herbal , Medicine, Chinese Traditional , Minerals , Quality Control
Article in Chinese | WPRIM | ID: wpr-401179


Objective The purpose of this study was to determine the contents of metallic elements of K,Ca,Mg,Zn,Mn,Cu and Fe in Polygonatum odoratum cultivated in Anhui province.Methods Atomic absorption spectrophotometry was utilized to determine the contents of metallic elements.Results The average contents of K,Ca,Mg,Zn,Mn,Cu and Fe were 12.7047mg/g,1.59083mg/g,0.55495mg/g,0.02034mg/g,0.01839mg/g,0.00664mg/g and 0.11791mg/g,respectively.The data were analyzed by t test.There was no significant difference between groups of each metallic element.Conclusion The contents of metallic elements of K,Ca,Mg,Mn and Fe incultivated Polygonatum odoratum were influenced easily by the culture base.