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1.
Barbarói ; (58): 195-217, jan.-jun. 2021.
Article in Portuguese | LILACS, INDEXPSI | ID: biblio-1150846

ABSTRACT

O presente artigo tem como objetivo traçar um paralelo entre o movimento feminista e o movimento antimanicomial procurando pontos de convergência e divergência entre ambos, a fim de verificar suas possíveis articulações. Para isso, por meio de revisão bibliográfica, busca-se contextualizar os movimentos sociais e realizar a análise histórica de ambos, afim de esclarecer suas motivações, formas de atuação na luta por direitos e atendimento de demandas dos sujeitos envolvidos com pretensões de alcançar transformações sociais. Dessa forma, o material discute as confluências e divergências entre o movimento feminista e antimanicomial, na tentativa de ampliar e construir o debate acadêmico acerca do assunto, que se transforma diariamente, de modo democrático e dialético. À guisa de conclusão, considera-se a necessidade de constituir novas formas de pensar sobre nossa condição histórica, com intuito de que isso possibilite a criação de estratégias de reinvenção e recriação constante de coletivos de luta e que promovam movimentos de resistências aos poderes instituídos que submetem mulheres e sujeitos em sofrimento psíquico, com objetivos de constituir mudanças e responsabilização social para que os absurdos tolerados por parcela considerável da sociedade não se reproduzam.(AU)


The present study aims to draw a parallel between the feminist and the anti-asylum movements looking for convergence and divergence points between both, in order to verify their possible articulations. To do so, through bibliographic review, it seeks to contextualize the social movements and carry out the historical analysis of both, in order to clarify their motivations, ways of acting in the fight for rights and meeting the demands of the subjects involved with the pretensions of achieving social transformations. This way, this paper discusses the confluences and divergences between the feminist and anti-asylum movement, in an attempt to broaden and build the academic debate on the subject, which changes daily, in a democratic and dialectical way. By way of conclusion, it is considered the need to constitute new ways of thinking about our historical condition, in order to allow the creation of strategies of constant reinvention recreation of fight collectives and that it promotes resistance movements against instituted powers which subject women and individuals in psychological distress, with the goal to constitute changes and social responsability so that the absurdities tolerated by a considerable part of society are not reproduced.(AU)


El presente estudio tiene como objetivo comprender las posibles conexiones entre el movimiento feminista y el movimiento contra el asilo buscando puntos de convergencia y divergencia entre ambos, con el fin de verificar sus posibles articulaciones. Para esto, a través de la revisión bibliográfica, se busca contextualizar los movimientos sociales y realizar el análisis histórico de ambos para aclarar sus motivaciones, formas de actuar en la lucha por los derechos y atender las demandas de los sujetos involucrados con las pretensiones de logrando transformaciones sociales. De esta manera, este trabajo discute las confluencias y divergencias entre el feminismo y el movimiento contra el asilo, en un intento por ampliar el debate académico sobre el tema, que cambia a diario, de manera democrática y dialéctica. En conclusión, consideramos la necesidad de establecer nuevas formas de pensar sobre nuestra condición histórica, con la intención de posibilidad de creación de estrategias de reinvención y recreación constante de la lucha colectiva y que promueva movimientos de resistencia a los poderes establecidos que someten a las mujeres y individuos en malestar psicológico, con fines constitutivos de cambios y responsabilidad social para que no se reproduzcan los absurdos tolerados por una parte considerable de la sociedad.(AU)


Subject(s)
Humans , Female , Women , Mental Health , Feminism , Capitalism , Social Norms
2.
Acta Paul. Enferm. (Online) ; 34: eAPE00243, 2021.
Article in Portuguese | LILACS, BDENF | ID: biblio-1278053

ABSTRACT

Resumo Objetivo: Identificar tipos penais no exercício da enfermagem e a existência de fatores relacionados a conduta profissional nas ocorrências éticas envolvendo tipos penais a partir da análise de depoimentos contidos nos processos éticos julgados no Conselho Regional de Enfermagem de São Paulo (Coren/SP). Método: Estudo exploratório-descritivo de abordagem quanti-qualitativa, nos processos éticos contendo ilícitos éticos considerados tipos penais. Os dados foram coletados nos processos ético-profissionais de enfermagem julgados pelo Coren/SP em 2012 e 2013. Resultados: Os tipos penais evidenciados na análise foram: abandono de incapaz; apropriação indébita; importunação sexual; estelionato; exercício ilegal de profissão; exercício ilegal da medicina; falsidade ideológica; extravio, sonegação ou inutilização de livro ou documento; falsificação de documento; falsificação, corrupção, adulteração ou alteração de produto destinado a fins terapêuticos ou medicinais; furto; homicídio; lesão corporal; maus tratos; peculato; tráfico de entorpecentes; uso de documento falso e vilipêndio a cadáver. Dos depoimentos emergiram sete categorias temáticas: Arrependimento Posterior; Percepção do ato ilícito; Fatores relacionados às condições de trabalho; Fatores Psicológicos e/ou sociais; Fatores Financeiros; Inobservância da responsabilidade e Dualidade. Conclusão: Os resultados do estudo foram de suma importância para identificar as ocorrências envolvendo tipos penais e com isso, a necessidade de se aprofundar a discussão sobre os problemas éticos na prática cotidiana do trabalho em enfermagem. Nessa perspectiva, o estudo denota a necessidade de se investir em melhores condições de trabalho e na formação qualificada dos profissionais de enfermagem no seu cotidiano, valorizando-os e incentivando-os à prática ética e humanizada do outro e de si.


Resumen Objetivo: Identificar tipos penales en el ejercicio de la enfermería y la existencia de factores relacionados con la conducta profesional en los casos éticos que incluyen tipos penales a partir del análisis de declaraciones en procesos éticos juzgados en el Consejo Regional de Enfermería de São Paulo (Coren/SP). Métodos: Estudio exploratorio y descriptivo, de enfoque cuantitativo y cualitativo en procesos éticos que contienen ilícitos éticos considerados tipos penales. Los datos se recolectaron de los procesos ético-profesionales de enfermería juzgados por el Coren/SP en 2012 y 2013. Resultados: Los tipos penales encontrados en el análisis fueron: abandono de incapaz; apropiación indebida; hostigamiento sexual; estafa; ejercicio ilegal de la profesión; ejercicio ilegal de la medicina; falsedad ideológica; pérdida, apropiación o inutilización de libro o documento; falsificación de documento; falsificación, corrupción, adulteración o modificación de producto destinado a fines terapéuticos o medicinales; hurto; homicidio; lesión corporal; malos tratos; malversación; tráfico de estupefacientes; uso de documento falso y profanación de cadáver. De las declaraciones surgieron siete categorías temáticas: Arrepentimiento posterior; Percepción del acto ilícito; Factores relacionados con las condiciones de trabajo; Factores psicológicos o sociales; Factores financieros; Incumplimiento de responsabilidad y Dualidad. Conclusión: Los resultados del estudio fueron de suma importancia para identificar los casos que incluyen tipos penales y, por lo tanto, también lo es la necesidad de profundizar la discusión sobre problemas éticos en la práctica cotidiana del trabajo de enfermería. Bajo esta perspectiva, el estudio denota la necesidad de invertir en mejores condiciones de trabajo y en la formación calificada de los profesionales de enfermería en su cotidianidad, además de valorizarlos e incentivarlos a una práctica ética y humanizada del otro y de sí mismo.


Abstract Objective: To identify criminal acts in nursing practice and the existence of factors related to professional behavior in ethical issues involving crime, based on the analysis of testimonies contained in ethical lawsuits judged by the Regional Nursing Council of São Paulo (Coren/SP). Method: Exploratory descriptive study with a quantitative and qualitative approach, analyzing ethical lawsuits containing ethical illicit acts considered criminal acts. Data were collected in the ethical-professional nursing lawsuits judged by Coren/SP in 2012 and 2013. Results: The criminal acts evidenced in the analysis were: abandonment of disabled person; embezzlement; sexual abuse; swindling; criminal impersonation; illegal practice of medicine; identity fraud; loss, fraud or destruction of a book or document; forgery of document; counterfeiting, contamination, adulteration or alteration of product intended for therapeutic or medicinal purposes; theft; bodily injury; maltreatment; peculation; drug trafficking; use of false document and abuse of corpse. The testimonies gave rise to seven thematic categories: Repentance for the past; Perception of the illegal act; Factors related to working conditions; Psychological and/or social factors; Financial factors; Non-admission of liability; with responsibility and Duality between perception and fact. Conclusion: The results of the study were extremely important to identify the occurrences involving criminal acts and demonstrate the need to broaden the discussion on ethical issues in daily nursing practice. In this perspective, the study demonstrates the need to invest in better working conditions and quality training for nursing professionals in their daily lives, valuing them and encouraging them to have an ethical and humane practice towards the other and themselves.


Subject(s)
Humans , Professional Practice/legislation & jurisprudence , Professional Practice/ethics , Liability, Legal , Dangerous Behavior , Ethics, Nursing , Nursing Care/ethics , Epidemiology, Descriptive , Evaluation Studies as Topic
3.
Article in Chinese | WPRIM | ID: wpr-912527

ABSTRACT

Flow cytometry has been widely used in clinical practice. Due to the powerful user-defined function of flow cytometry, different instrument settings among manufacturers and lack of standard materials, the comparability of results needs to be improved and flow cytometry is facing the great challenge of normalization and standardization. In this paper, the recent progress of normalization and standardization about flow cytometry was discussed form the aspects of standardizing operation protocol, including specimen and centrifugation, standardizingantibody selection and panel combination and ensuring instrument and data analysis consistency.

4.
Article in Chinese | WPRIM | ID: wpr-906221

ABSTRACT

Objective:To construct the knowledge base of Tibetan medicine prescriptions and explore to standardize the names of Tibetan medicine prescriptions. Method:By using the concept of "man-machine combination",through the construction of Tibetan medicine terminology glossary (data sources: national drug standards,local drug standards,text classics on Tibetan medicines,etc.),the terminology glossary of Tibetan medicine prescriptions was mined. Upon its combination with expert review,the text association between Tibetan medicine prescriptions and various drug standards and dictionaries was constructed,and the standardization methods and techniques of prescription drug names were explored. Result:In this paper,the Tibetan medicine prescriptions approved for marketing in China were taken as the research object,and various inconveniences caused by the inconsistency between the names of prescriptions and the names of medicinal herbs were revealed. This paper also discussed the design ideas on name standardization of Tibetan medicines from three levels: text association,optimization of evaluation methods,and formation of expert decision-making system. We put forward a five-in-one (screening, evaluation, reviewing, fixing, and renewing) research model of Tibetan medicine name standardization. The construction,functions and advantages of the database and thesaurus of Tibetan medicine prescriptions were described in detail, and in combination with the text notes, association between the standard medicinal materials and the prepared prescriptions was then established. Conclusion:The text association method in this paper can accurately reflect the nonstandard names of Tibetan medicine prescriptions. Combined with expert review,it can be, to a certain extent, extended to the standardization of herb names in prescriptions with large scale of or more complex network structures.

5.
Horiz. sanitario (en linea) ; 19(3): 441-452, sep.-dic. 2020. tab, graf
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1154341

ABSTRACT

Resumen Objetivo: Identificar facilitadores y obstáculos en la implementación del programa Meta Salud Diabetes, una intervención educativa diseñada para disminuir el riesgo de padecer enfermedades cardiovasculares en personas con diabetes, que participan en Grupos de Ayuda Mutua de la Secretaría de Salud, en el norte de México. Materiales y métodos: Estudio de corte cualitativo. A partir de la Teoría del Proceso de Normalización, en particular del constructo de contribución, se analiza la información que da cuenta de la experiencia del personal encargado de la implementación del programa, en cuatro centros de salud seleccionados para este trabajo. Las fuentes constan de bitácoras de contacto con las encargadas de los Grupos de Ayuda Mutua, relatorías de reuniones de retroalimentación con éstas, diarios de campo de la observación no participante de las sesiones de Meta Salud Diabetes y entrevistas semiestructuradas. Resultados: Meta Salud Diabetes pudo ser implementado durante 13 semanas, en los centros de salud que participaron en el estudio. Quienes lo facilitaron, reconocieron su utilidad como un modelo educativo para mejorar las prácticas de autocuidado en las personas con diabetes. Se documentó que el acompañamiento institucional es muy importante para la implementación del programa. Conclusiones: Para la implementación del programa en el futuro, se requiere la asignación sistemática de recursos a los Grupos de Ayuda Mutua, el reconocimiento del trabajo de quienes los coordinan, la mejora en los procesos de supervisión, la contratación de más personal y la colaboración de diferentes profesionales de la salud. El enfoque de la Teoría del Proceso de Normalización para el análisis de la contribución de los agentes, permitió identificar los factores que facilitaron u obstaculizaron la implementación de Meta Salud Diabetes en los casos estudiados. Una limitación de este tipo de investigaciones es la dificultad de aislar el impacto que tienen en los diferentes agentes.


Abstract Objective: Identify facilitators and barriers to implementing Meta Salud Diabetes program, an educational intervention designed to reduce the risk of cardiovascular disease in people with diabetes who participate in Grupos de Ayuda Mutua [Self-help groups] organized by the Ministry of Health in northern Mexico. Materials and methods: This is a qualitative study based on Normalization Process Theory, mainly the "contribution" construct, which analyzes information describing the experience of health personnel in charge of implementing the intervention in four health care centers selected for this article. Data sources include contact logs with Grupos de Ayuda Mutua facilitators and reports from feedback meetings, field notes from non-participant observation of the Meta Salud Diabetes sessions and semi-structured interviews. Results: Meta Salud Diabetes was succesfully implemented for 13 weeks in the health care centers selected for this study. Facilitators recognized its usefulness as an educational model that improves the self-care practices of people with diabetes. The importance of institutional support for the implementation of Meta Salud Diabetes was also documented. Conclusions: Future implementation of the program requires the systematic allocation of resources to the Grupos de Ayuda Mutua, recognition of the work of those who coordinate them, improvement of supervision processes, employing of more staff and collaboration between different health professionals. Using Normalization Process Theory to analyze agentic contribution allowed us to identify the factors that facilitated or hindered the implementation of Meta Salud Diabetes in the studied groups. However, a limitation of this type of study is the difficulty of isolating the specific impact on different agents.


Resumo Objetivo: Identificar facilitadores e obstáculos na implementação do programa Meta Salud Diabetes, uma intervenção educacional destinada a reduzir o risco de doença cardiovascular em pessoas com diabetes que participam de Grupos de Ajuda Mútua do Ministério da Saúde no norte do México. Materiais e métodos: Estudo qualitativo baseado na Teoria do Processo de Normalização, particularmente no construto "contribuição", são analisadas informações que explicam a experiência do equipe na implementação e coordenação do programa em quatro centros de saúde selecionados para este trabalho. As fontes de informação incluem registros de contatos com os funcionarios dos Grupos de Ajuda Mútua, relatórios sobre reuniões de feedback com eles, jornais de observação de campo não participante das sessões de Meta Salud Diabetes e entrevistas semiestruturadas. Resultados: Meta Salud Diabetes pôde ser implementado por 13 semanas nos centros de saúde que participaram do estudo. Os facilitadores reconheceram sua utilidade como um modelo educacional que aprimora as práticas de autocuidado para pessoas com diabetes. A importância do apoio institucional para a implementação da Meta Salud Diabetes foi documentada. Conclusões: Para a implementação do programa no futuro, é necessária a alocação sistemática de recursos aos Grupos de Ajuda Mútua, o reconhecimento do trabalho daqueles que os coordenam, a melhoria dos processos de supervisão, a contratação de mais pessoal e a colaboração de diferentes profissionais de saúde. A abordagem da Teoria do Processo de Normalização para analisar a contribuição dos agentes, permitiu identificar os fatores que facilitaram ou dificultaram a implementação do Meta Salud Diabetes nos casos estudados. Uma limitação desse tipo de pesquisa é a dificuldade de isolar o impacto que eles têm sobre diferentes agentes.


résumé est disponible dans le document

6.
RECIIS (Online) ; 14(3): 724-733, jul.-set. 2020. ilus
Article in Spanish | LILACS | ID: biblio-1121946

ABSTRACT

En esta entrevista a Reciis, Miquel Térmens discute la importancia de la preservación digital para crear un sistema de salud que sea bueno no solo para el futuro, pero para el presente. Estamos en una fase de recopilación y almacenamiento de una gran cantidad de datos sobre el nuevo coronavirus para asegurar su rápida utilización, y su preservación a largo plazo es de interés tanto de los gobiernos como de los grupos de investigación que están trabajando a favor de las soluciones. El gran reto de nuestro presente es investigar cómo hacer preservación digital a una nueva escala, incorporando datos de las redes sociales, datos de investigación y Big Data, pero eso solo va a ser posible con normalización y planificación. Miquel Térmens Graells es doctor en Documentación por la Universidad de Barcelona, es profesor titular y decano de la Facultad de Información y Medios Audiovisuales de la misma universidad.


Subject(s)
Humans , Organization and Administration , Health Systems , Data Curation , Big Data , Data Analysis , Data Collection , Information Storage and Retrieval , Access to Information
7.
Rev. bras. enferm ; 73(6): e20180950, 2020. graf
Article in English | LILACS-Express | LILACS, BDENF | ID: biblio-1125892

ABSTRACT

ABSTRACT Objectives: to analyze theoretical conceptions of Eliot Freidson's Sociology of Professions scoped on health and nursing professions. Methods: Eight nurses were interviewed, all involved in the development of the professional Council on the timeframe from 1975 to 1986. Documental resources were Laws, Ordinances, Resolutions, Reports, Meeting Minutes and Public Deeds. Information was organized as from literature and Eliot Freidson's conceptions, and thematic content analysis was carried out. Results: the concepts authored by Eliot Freidson allowed for the development of a concept chart that portrays the nursing profession and that may be expanded for the other occupations in the health field, in consonance with professional organization in the country. Final Considerations: Eliot Freidson's framework, in interpretation for nursing, consolidates the profession with relative autonomy, expertise by Nursing Care Systematization and credentialism by professional normalizations.


RESUMEN Objetivos: analizar las concepciones teóricas de la Sociología de las Profesiones de Eliot Freidson para el alcance de las profesiones de salud y enfermería. Métodos: estudio sociohistórico cualitativo, con fuentes orales y documentales. Se entrevistó a ocho enfermeras involucradas en el desarrollo del Consejo Profesional en el período de 1975 a 1986. Los documentales fueron Leyes, ordenanzas, resoluciones, informes, actas de reuniones y escrituras públicas. La información se organizó a partir de la literatura y las concepciones de Eliot Freidson, y se realizó un análisis de contenido temático. Resultados: los conceptos emitidos por Eliot Freidson permitieron la creación de un marco conceptual que represente a la profesión de enfermería, que podría ampliarse a otras profesiones de la salud, en línea con la organización profesional del país. Consideraciones Finales: el marco de Eliot Freidson, en interpretación de enfermería, consolida la profesión con relativa autonomía, experiencia en Sistematización de la Atención de Enfermería y credencialismo en los estándares profesionales.


RESUMO Objetivos: analisar as concepções teóricas da Sociologia das Profissões de Eliot Freidson para o âmbito das Profissões da Saúde e da Enfermagem. Métodos: estudo qualitativo sócio-histórico, com fontes orais e documentais. Foram entrevistados oito enfermeiros envolvidos no desenvolvimento do Conselho profissional no recorte temporal de 1975 a 1986. As documentais foram Leis, Portarias, Resoluções, Relatórios, Atas de Reuniões e Escrituras Públicas. As informações foram organizadas a partir da literatura e concepções de Eliot Freidson, e realizada análise de conteúdo temática. Resultados: os conceitos emitidos por Eliot Freidson permitiram a criação de um Quadro conceitual que representa a Profissão Enfermagem, podendo ser ampliado para as demais profissões da área da Saúde, em consonância com a organização profissional no país. Considerações Finais: o referencial de Eliot Freidson, em interpretação para a Enfermagem, consolida a profissão com autonomia relativa, expertise pela Sistematização da Assistência de Enfermagem e credencialismo pelas normalizações profissionais.

8.
Article in Chinese | WPRIM | ID: wpr-872013

ABSTRACT

Objective This paper focuses on the field of clinical medicine,with the aim of verifying the feasibility of interdisciplinary literature evaluation model based on feature matching method,to provide support for further interdisciplinary scientific research evaluation.Methods Feature matching method,Delphi expert enquiry,and normalization method were adopted to establish an evaluation system in clinical medicine,which was further verified by case studies.Results The normalization coefficient reflects the difficulty of publishing articles with high impact factors.Through the process of feature matching and normalization,it was found that compared with the fields of Neurology,Psychiatry and Surgery,researchers in the fields of Oncology and Internal Medicine were more likely to publish articles with high impact factors.Conclusions Through case analysis,this study verifies the feasibility of interdisciplinary scientific paper evaluation system.The interdisciplinary paper evaluation system based on feature matching method and normalized evaluation method comprehensively considers the characteristics of various disciplines of clinical medicine and provides a new idea for the evaluation of clinical scientific research talents.

9.
Acta Pharmaceutica Sinica B ; (6): 2018-2036, 2020.
Article in English | WPRIM | ID: wpr-881097

ABSTRACT

Tumor vasculature is characterized by aberrant structure and function, resulting in immune suppressive profiles of tumor microenvironment through limiting immune cell infiltration into tumors, endogenous immune surveillance and immune cell function. Vascular normalization as a novel therapeutic strategy tends to prune some of the immature blood vessels and fortify the structure and function of the remaining vessels, thus improving immune stimulation and the efficacy of immunotherapy. Interestingly, the presence of "immune‒vascular crosstalk" enables the formation of a positive feedback loop between vascular normalization and immune reprogramming, providing the possibility to develop new cancer therapeutic strategies. The applications of nanomedicine in vascular-targeting therapy in cancer have gained increasing attention due to its specific physical and chemical properties. Here, we reviewed the recent advances of effective routes, especially nanomedicine, for normalizing tumor vasculature. We also summarized the development of enhancing nanoparticle-based anticancer drug delivery

10.
Article in Chinese | WPRIM | ID: wpr-819126

ABSTRACT

@#The main treatment of head and neck cancer is comprehensive sequential treatment, but the 5-year overall survival rate is less than 50%. Strategies to further improve the curative effect of head and neck cancer are urgently needed in the clinic. Recombinant human vascular endostatin is an antiangiogenesis drug targeting vascular endothelial cells, which has a certain inhibitory effect on tumors. The treatment of malignant tumors by drugs alone is not significantly better than chemoradiation, but combined with radiotherapy and chemotherapy, it can increase the effect of radiotherapy and chemotherapy without drug resistance by changing the distribution of blood vessels, reducing oxygen and normalizing blood vessels. Head and neck tumor treatment has certain advantages. New tumor treatments are expected. The results of a literature review showed that the mechanism of action of recombinant human endostatin mainly includes regulating the matrix protein inside and outside the endothelial cells to influence neovascularization, acting on receptors related to the surface of endothelial cells, reversing abnormal neovascularization to achieve vascular normalization, inhibiting hypoxia inducible factor to improve the hypoxic status of the tumor area, and regulating the cell cycle to ensure the tumor cells are sensitive to radiation in the sensitive period, and vascular normalization can increase the effect of radiotherapy. This treatment has a good synergistic effect with radiotherapy and chemotherapy of head and neck tumors and has a good effect on advanced head and neck tumors.

11.
Sex., salud soc. (Rio J.) ; (33): 42-58, set.-dez. 2019.
Article in Spanish | LILACS | ID: biblio-1059088

ABSTRACT

Resumen El presente artículo se propone, siguiendo el método genealógico foucaultiano, analizar la eficacia productiva y la violencia normativa que constituye a la ginecología en una tecnología de hetero-cis-normalización que produce una distribución diferencial de la precaridad, afectando principalmente a corporalidades y modos de vida lesbianos (cis y trans), transmasculinos, no-binarixs, bi y pansexuales. Para desarrollar estas tesis recuperaré, en primer lugar, los desarrollos butlerianos en torno a la heterosexualidad obligatoria, las normas sexo-generizadas y la vulnerabilidad, para pensar, desde allí, a la ginecología como una técnica de precarización. En segundo lugar, y recuperando las tesis de Rohden, Cabral y Preciado, desarrollaré el modo en que la ginecología opera como una "prótesis de género" que organiza y disciplina cuerpos a partir de un sistema binario. Para concluir, sostendré siguiendo a Foucault que esto implica una especie de extraña "paradoja" para la ginecología, en la medida en que la imposición de su matriz hetero-cis-normativa redunda en una inducida, y sistemática, desatención y descuido de la salud ginecológica de las personas LGTB.


Resumo A partir do método genealógico foucaultiano, o presente artigo tem o intuito de analisar a eficácia produtiva e a violência normativa que configura a ginecologia como tecnologia de hetero-cis-normalização, produzindo uma distribuição diferencial da precariedade que afeta, principalmente as corporeidades e modos de vida lésbicos (cis e trans), transmasculinos, não-binarixs, bi e pansexuais. Para tal trarei à tona, em primeiro lugar, as análises butlerianas em torno da heterossexualidade compulsória, as normas sexo-generificadas e a vulnerabilidade para pensar a ginecologia como técnica de precarização. Em segundo lugar, e recuperando os supostos de Rhoden, Cabral e Preciado, desenvolverei os modos em que a ginecologia opera como uma "prótese de gênero" que organiza e disciplina corpos a partir de um sistema binário. Para concluir, e seguindo a Foucault, sustentarei a ideia que isso supõe uma espécie de estranho "paradoxo" para a ginecologia; uma desatenção induzida e sistemática e um desleixo da saúde ginecológica das pessoas LGTB.


Abstract This paper seeks to examine the productive effectiveness and normative violence of Gynecology, following Foucault's genealogical method, in terms of a technology of heterocis-normalization that induces a differential distribution of precarity, affecting mainly lesbian (cis or trans), transmasculine, bi, non-binary and pansexual bodies and forms of life. In order to develop this analysis, I will first consider Butler´s developments on compulsive heterosexuality, sex and gender norms and vulnerability as a way of thinking Gynecology as a technic of precarity. Secondly, and following Rohden´s, Cabral´s and Preciado´s thoughts, I will argue that Gynecology operates as a "gender prosthesis" that organizes and discipline bodies through a binary system. Finally, and following Foucault, I will conclude that this implies a paradoxical situation for Gynecology, since its heteronormative matrix produces and induces a systematical inattention and carelessness of LGTB people.


Subject(s)
Humans , Female , Sexuality , Heterosexuality , Sexual and Gender Minorities , Gender-Based Violence , Gender Norms , Gynecology , Physician-Patient Relations , Women's Health , Medical Care , Ethics, Medical , Social Stigma , Sexism
12.
Rev. Fac. Nac. Salud Pública ; 37(3): 15-24, sep.-dic. 2019. tab
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1092008

ABSTRACT

Resumen Objetivo: Identificar los factores asociados a la capacidad laboral de las personas mayores de 50 años, excombatientes de los grupos al margen de la ley, adscritos a la Agencia para la Reincorporación y la Normalización. Metodología: Estudio observacional, analítico de fuente de información primaria, con 239 personas mayores en proceso de reintegración, encuestados en cinco lugares de Colombia. Se calculó la razón de prevalencia cruda y ajustada, mediante una regresión logística no condicional, con valor de p< 0,05, considerada una asociación estadísticamente significativa. Resultados: El 71,5 % de las personas mayores de 50 años se encuentran laborando, principalmente, en el sector informal. La dependencia funcional se asocia, aunque no de forma significativa, con ser hombre, soltero, no tener limitaciones para ver o moverse, y mostrar habilidades en la conducción de vehículos y el manejo de computadores. Presentaron mayor limitación en el campo laboral los que tienen dificultades para hablar y un menor nivel educativo. Conclusión: La adaptación a la vida laboral de las personas mayores excombatientes de los grupos al margen de la ley puede facilitarse con la implementación de enfoques diferenciales, programas educativos formales e informales, el uso de ayudas ortopédicas, la generación de estrategias de acceso al empleo y estrategias saludables que promuevan su salud y atención a los efectos de la guerra.


Abstract Objective: To identify factors associated with work capacity in people being over 50 years old, who used to be ex-combatants from groups outside the law, and who are now registered in the Agency for Reincorporation and Normalization. Methodology: Observational analytic study using primary sources of information from 239 senior subjects in the reincorporation process. All of them were surveyed in five different locations in Colombia. Crude and adjusted prevalence ratios were calculated through unconditional logistic regression, with a p-value of < 0.05, which is considered a statistically significant association. Results: 71.5 % of subjects being over 50 years old work mainly in the informal sector. A functional dependency is associated, though not significantly, with being a single man, or a man without sight or movement disabilities, or a man having driving and computer skills. Those with speech disorders and a lower educational level presented greater limitations in the labor field. Conclusion: Adaptation processes to work life for senior ex-combatants from groups outside the law may be facilitated through the implementation of differential approaches, formal and informal educational programs, use of orthopedic aids, generation of strategies for access to employment and health strategies that promote their wellbeing and attention to the effects of war.


Resumo Objetivo: Identificar os fatores associados à capacidade laboral de pessoas acima de 50 anos, excombatentes de grupos fora da lei, vinculados à Agência de Reintegração e a vida Normal. Metodologia: Estudo observacional e analítico da fonte primária de informações, com 239 idosos em processo de reintegração, pesquisados em cinco locais da Colômbia. Calculou-se a razão de prevalência bruta e ajustada, através de uma regressão logística não condicional, com valor de p <0,05, considerada uma associação estatisticamente relevante. Resultados: O 71,5% das pessoas com mais de 50 anos estão trabalhando principalmente no setor informal. A dependência funcional está associada, embora não significativamente, a ser homem, solteiro, sem limitações para ver ou se mover e mostrar habilidades em dirigir veículos e trabalho com computadores. Apresentaram maiores limitações no trabalho aqueles que têm dificuldades para falar e com menor nível educacional. Conclusão: A adaptação à vida profissional dos idosos excombatentes dos grupos fora da lei pode ser facilitada com a implementação de abordagens diferenciais, programas educacionais formais e informais, uso de aparelhos ortopédicos, geração de estratégias de acesso ao emprego e estratégias saudáveis que promovam sua saúde e atenção aos efeitos da guerra.

13.
Article in Chinese | WPRIM | ID: wpr-753874

ABSTRACT

Objective To evaluate the nutrional status and malnutrition risks of hospitalized children with acute lymphoblastic leukemia (ALL),provide nutrition support for subsequent treatment,lower nutritional risks and improve therapeutic effects;to complete the statistical analysis of height and weight across age through data normalization.Methods A total of 592 children diagnosed ALL from August 2014 to September 2016 at Beijing Children's Hospital were enrolled,and the directly measured height and weight which reflected the nutritional status of children were collected and normalized.Nutritional risk screening was completed by STAMP screening tool and the nutritional status was evaluated by three Z scores HAZ<-2,WAZ<-2 and WHZ<-2.The effects of nutrition intervention were investigated by weight,hemoglobin and albumin changes between before and after L-asp treatment.Results The Z score test showed that there was no significant difference between the nutritional status of pretreatment ALL patients (0.34% growth retardation,2.36% lower body weight,0.17% emaciation) and normal healthy children (3% malnutrition);after comparing the STAMP nutritional risk assessment and t test results for children with ALL,it was found that the proportion of children with high malnutrition risk (score≥4) was 9.71%,which had a strong correlation with body mass index;the children with body mass index less than 0.80 (50% children having malnutrition) or greater than 1.30 (20% children having malnutrition) had a higher risk of malnutrition,and the body mass indexof the high-risk group (0.852 kg/m2) were significantly lower than that of the low risk group (1.051 kg/m2,score ≤ 3);there were significant differences in height and weight between children with STAMP ≤ 3 and STAMP ≥ 4 (all P <0.05) Nutritional interventions made no significant weight change during treatment;For children with STAMP ≤3 and STAMP ≥4 in L-asp treatment,the hemoglobin value changed from (87.46± 19.27) g/L to (95.12±13.51) g/L and (101.55±21.97) g/L to (95.05±11.22) g/L respectively (all P=0.001);The albumin of children with STAMP≤3 changed from (40.63±4.149) g/L to (41.20±5.266) g/L in treatment and that of children with STAMP ≥4 changed from (40.96±8.429) g/L to (42.17±3.574) g/L in treatment (P=0.20,0.05).Conclusion There are no obvious indications of malnutrition in children with ALL,but nearly 10 % of them have malnutrition risks.Special dietary guidance is needed during the treatment.Nutrition intervention is effective in the treatment of L-asp.Normalized data is more convenient to use in statistical analysis with more accurate results,which can be used as a supplementary method for cross-age group statistical analysis of children's height,weight and other parameters.

14.
Article in Chinese | WPRIM | ID: wpr-773742

ABSTRACT

The best time of tumor intervention is before the formation of tumor. However,due to the limited number of tumor cells,it is difficult to quantify tumor cells and immunity by the current methods available( such as CTC,ct DNA). This affects the tumor prevention in this period,and the in-depth detection,intervention and evaluation of traditional Chinese medicine( TCM)( tumor) prevention. Due to the limitations of the current detection,the evaluation system turns to detect tumor neoantigen-specific CTL( naCTL) that are directly relating to tumor cells and proliferate to high order of magnitudes after activation,and immune repertoire( TCR/BCR/HLA) effective diversity,introduces immune checkpoints,uses information of " disease" in Western medicine and " syndrome" in TCM( prevention),and sets up a multi-dimensional statistical immunity model using a variety of data analysis and related algorithms. This model can amplify the ultra-early information of tumor,indirectly evaluate the quantity and status of tumor cells,and provide quantitative measurement and new evaluation methods for the normalization of immunity and TCM( tumor) prevention. This model is not only one of important evaluation methods for resisting tumor immunity and treating TCM( tumor) prevention,but also will reveal the scientific connotation of TCM syndrome from the perspective of immunology.


Subject(s)
Drugs, Chinese Herbal , HLA Antigens , Humans , Medicine, Chinese Traditional , Neoplasms , Allergy and Immunology , Receptors, Antigen, B-Cell , Receptors, Antigen, T-Cell
15.
Chinese Journal of Oncology ; (12): 421-428, 2019.
Article in Chinese | WPRIM | ID: wpr-805535

ABSTRACT

Objective@#To evaluate the feasibility of intravoxel incoherent motion diffusion-weighted magnetic resonance imaging (IVIM-DWI MRI) in the evaluation of tumor vascular normalization in a mouse model of colorectal cancer induced by recombinant human endostatin (rhES).@*Methods@#The CT26 colorectal cancer xenograft model of BALB/c mice were established and divided into rhES group and control group, with 20 mice in each group. The mice of rhES group were intravenously injected with rhES 5 mg·kg-1·d-1 once daily for 12 days, while the mice of the control group were intravenously injected with the same volume of 0.9% saline. 5 mice of rhES group and control group were randomly selected to perform IVIM-DWI MRI as following times: before treatment and four, eight, twelve days after treatment. The parameters of IVIM-DWI were recorded, including true diffusion coefficient(D), pseudo-diffusion coefficient (D*) and perfusion fraction (f). Meanwhile, microvessel density (MVD), pericyte coverage and tumor perfusion in tumor tissues were detected by immunofluorescence, respectively.@*Results@#The tumor volumes of control group and rhES group before treatment were (154.42±24.65) mm3 and (174.24±28.27)mm3, respectively, without statistically significant difference (P=0.440). From day 2 to day 12 after treatment, the tumor volume of rhES group was significantly smaller than that of control group (all P<0.05). There were no statistical significances of D value between the rhES group and control group before and after treatment (all P>0.05). The D* values of the rhES group were (10.940±2.834)×10-3mm2/s and (12.940±2.801)×10-3mm2/s in day 4 and 8 after treatment respectively, significantly higher than (6.980±1.554)×10-3mm2/s and (7.898±1.603)×10-3mm2/s of control group (P<0.05). Moreover, compared with control group, the D* value of rhES group was significantly lower in day 12 (6.848±1.460)×10-3mm2/s vs (9.950±2.596)×10-3mm2/s, (P<0.05). The f value of rhES group in day 8 was (0.226±0.021)%, significantly higher than (0.178±0.016)% of control group (P<0.01). The MVD of rhES group was significantly lower than that of control group (P<0.05), while the pericyte coverage and tumor perfusion of rhES group were significantly higher than those of control group in day 4 and 8 after treatment (all P<0.05). In addition, we found D* value of IVIM-DWI in rhES group was significantly related with MVD, pericyte coverage and tumor perfusion (r=-0.354, r=0.555, r=0.559, all P<0.05). Meanwhile, the f value in rhES group was also significantly related with MVD, pericyte coverage and tumor perfusion (r=-0.391, r=0.538, r=0.315, all P<0.05).@*Conclusions@#IVIM-DWI MRI can effectively evaluate the vascular normalization in rhES-induced CT26 colorectal tumor.The parameters D* and f are closely related to intratumorally microvessel density, pericyte coverage and perfusion, which can effectively monitor the occurrence of tumor vascular normalization time.

16.
Article in Chinese | WPRIM | ID: wpr-801894

ABSTRACT

Objective:To compare the total daily doses of 16 active components in big honeyed pills, concentrated pills and tablets of Fuzi Lizhongwan. Method:Three dosage forms of Fuzi Lizhongwan were prepared according to the process described in the literature. RRLC-QqQ-MS was employed to analyze the contents of 16 active ingredients with mobile phase of 0.1%formic acid aqueous solution-0.1%formic acid acetonitrile solution for gradient elution,the separation was performed on a Accucore RP-MS column(2.1 mm×100 mm, 2.6 μm) with a flow rate of 0.3 mL·min-1 and the column temperature at 30℃, the mass spectrometry condition was electrospray ion source, positive and negative ion switching mode for detection, multi-reaction monitoring mode(MRM) for scanning. The contents of 16 active ingredients were calculated, and the normalization arithmetic method was used for comparing the total daily doses of these active ingredients in three dosage forms of Fuzi Lizhongwan. Result:Processed products of Aconiti Lateralis Radix Praeparata were used as raw powder in preparation process of the three dosage forms, so there was no significant difference in the contents of six alkaloids in the three dosage forms, while the contents of other 10 active ingredients from Zingiberis Rhizoma, Codonopsis Radix, Atractylodis Macrocephalae Rhizoma and Glycyrrhizae Radix et Rhizoma Praeparata cum Melle were significantly higher in big honeyed pills than those in concentrated pills or tablets(PConclusion:The total daily doses of 16 active ingredients in the three dosage forms of Fuzi Lizhongwan are significantly different caused by preparation process, prescription and dosage.

17.
Article in English | WPRIM | ID: wpr-763804

ABSTRACT

Entity normalization, or entity linking in the general domain, is an information extraction task that aims to annotate/bind multiple words/expressions in raw text with semantic references, such as concepts of an ontology. An ontology consists minimally of a formally organized vocabulary or hierarchy of terms, which captures knowledge of a domain. Presently, machine-learning methods, often coupled with distributional representations, achieve good performance. However, these require large training datasets, which are not always available, especially for tasks in specialized domains. CONTES (CONcept-TErm System) is a supervised method that addresses entity normalization with ontology concepts using small training datasets. CONTES has some limitations, such as it does not scale well with very large ontologies, it tends to overgeneralize predictions, and it lacks valid representations for the out-of-vocabulary words. Here, we propose to assess different methods to reduce the dimensionality in the representation of the ontology. We also propose to calibrate parameters in order to make the predictions more accurate, and to address the problem of out-of-vocabulary words, with a specific method.


Subject(s)
Dataset , Information Storage and Retrieval , Methods , Semantics , Vocabulary
19.
Psicol. rev. (Belo Horizonte) ; 24(1): 291-301, jan.-abr. 2018.
Article in Portuguese | LILACS | ID: biblio-1020238

ABSTRACT

O artigo pretende, com base na análise do poder empreendida por Michel Foucault, refletir sobre os mecanismos de normalização e as lutas contemporâneas anti-identitárias. Em primeiro lugar, é analisada a crítica desenvolvida na primeira metade da década de 1970 à filosofia política tradicional e ao discurso jurídico do poder, quando então o foco de suas análises foi dirigido para outros mecanismos de natureza disciplinar ou biopolítica. Em segundo lugar, o estudo é dirigido para a maneira como Foucault via as lutas contemporâneas, tomadas como formas de resistência aos mecanismos de normalização, entendidas em seus últimos anos de vida como uma arte de não ser governado de determinada maneira. Por fim, o trabalho aborda a guerra social em curso hoje no Brasil, tomando-a como mais um exemplo de investida normalizadora que torna ainda mais oportuno lembrar Foucault, em especial a sua postura de resistência.


This article aims to investigate the mechanisms of normalization and the contemporary anti-identity struggles starting from the analysis of power undertaken by Michel Foucault. First of all, the criticism developed in the first half of the 1970’s towards the traditional political philosophy and legal discourse of power is brought into analysis, at the time when the focus of their analysis was directed towards other disciplinary and biopolitical mechanisms. Secondly, the study focus on how Foucault saw contemporary struggles, taken as forms of resistance against the mechanisms of normalization, understood in his final years as an art of not being governed in a certain way. Finally, the study will address the ongoing social war in Brazil, taking it as another example of normalizing attack that makes it even more appropriate to remember Foucault, especially his attitude of resistance.


El artículo pretende, a partir del análisis del poder emprendido por Michel Foucault, reflexionar sobre los mecanismos de normalización y las luchas contemporáneas anti-identitarias. En primer lugar, se analiza la crítica desarrollada en la primera mitad de los años 1970 a la filosofía política tradicional y al discurso jurídico del poder, cuando entonces el foco de sus análisis se dirigió hacia otros mecanismos de naturaleza disciplinaria o biopolítica. En segundo lugar, el estudio se dirige a la manera como Foucault veía las luchas contemporáneas, tomadas como formas de resistencia a los mecanismos de normalización, entendidas en sus últimos años de vida como un arte de no ser gobernado de determinada manera. Por último, el trabajo abordará la guerra social en curso hoy en Brasil, entendida como un ejemplo más de ataque normalizador que hace aún más oportuno recordar Foucault, en especial su postura de resistencia.


Subject(s)
Enacted Statutes , Philosophy , Politics
20.
Psicol. soc. (Online) ; 30: e169213, 2018.
Article in Portuguese | LILACS | ID: biblio-976667

ABSTRACT

Resumo Os andarilhos de estrada são indivíduos que percorrem longas distância pelas rodovias do país com um saco às costas ou puxando um carrinho de mão no qual carregam todos os seus pertences, sem destino certo ou trajetos preestabelecidos. Essa pesquisa teve por finalidade analisar o tratamento dado por uma concessionária de rodovias aos andarilhos dentro de suas políticas de gestão do trânsito e fluxo de pedestres pelos acostamentos. Foi realizada uma entrevista com o profissional responsável pela administração de uma importante rodovia paulista, posicionada num dos principais corredores de transporte do país e na qual são encontrados frequentemente os andarilhos. Os resultados indicaram que as estratégias de controle utilizadas pela concessionária de rodovia incluem ações de vigilância e medidas administrativas que, sob o efeito da sanção normalizadora, supervisionam e distribuem os andarilhos nesse espaço aberto e anônimo por onde circulam as multiplicidades.


Resumen Andariegos o caminantes de carretera son individuos que caminan largas distancias por las carreteras de Brasil, sin destino o trayectos preestablecidos, con una bolsa en la espalda o tirando de un carrito de mano donde llevan todas sus pertenencias. Esta investigación tuvo por finalidad analizar el tratamiento ofrecido por una concesionaria de carretera a los caminantes según sus políticas de gestión de tránsito y flujo de pedestre por los arcenes. Fue realizada una entrevista con el profesional responsable por la administración de una importante carretera en el estado de São Paulo, situada en uno de los principales corredores de transportes del país donde esos andariegos son vistos con frecuencia. Los resultados han indicado que las estrategias de control utilizadas por la concesionaria de carretera incluyen acciones de vigilancia y medidas administrativas que, bajo el efecto de la normalización, supervisan y distribuyen los caminantes en este espacio abierto y anónimo por donde circulan las multiplicidades.


Abstract The Brazilian highway wanderers are individuals who walk long distances through the country highways with a bag on their backs or pulling a wheelbarrow in which they carry all their belongings, with no defined destination or pre-established routes. This research aimed to analyze the treatment given by a highway concessionaire to the highway wanderers within their policies of traffic management and pedestrian transit along the roadsides. An interview was conducted with a professional who is responsible for the management of an important highway in São Paulo State, located in one of the main transport walkways where highway wanderers are often seen. The results indicated that the control strategies utilized by the highway concessionaire include vigilance actions and the administrative measures that, under the normalization effects, supervise and distribute the Brazilian highway wanderers in this open and anonymous space through which multiplicities circulate.


Subject(s)
Humans , Male , Female , Transients and Migrants , Roads/policies , Social Control Policies/organization & administration
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