1.
West Indian med. j
;
42(3): 121-3, Sept. 1993.
Article
in English
| LILACS
| ID: lil-130582
ABSTRACT
A randomized controlled trial of Solcoseryl, DuoDerm and conventional conservative therapy with Eusol has been performed in 32 patients with homozygous sickle-cell (SS) disease. After 12 weeks' baseline observation, patients were randomized to one of three therapies and monitored for a further 12 weeks. Of 44 ulcerated legs, 20 received control treatment, 12 Solcoseryl and 12 DuoDerm. DuoDerm was generally unacceptable, and two-thirds of the patients defaulted from this treatment. Solcoseryl increased ulcer healing compared to the controls but the difference was not significant. Solcoseryl was well tolerated and may have a role in the treatment of chronic leg ulcers of sickle-cell disease.
Subject(s)
Humans , Male , Female , Actihaemyl/therapeutic use , Colloids/therapeutic use , Anemia, Sickle Cell/complications , Leg Ulcer/drug therapy , Occlusive Dressings , Randomized Controlled Trials as Topic , Patient Compliance , Jamaica
2.
Article
in English
| IMSEAR
| ID: sea-41300
Subject(s)
Actihaemyl/therapeutic use , Adolescent , Adult , Aged , Child , Child, Preschool , Chronic Disease , Corneal Ulcer/drug therapy , Female , Gels , Humans , Male , Middle Aged , Prospective Studies , Tissue Extracts/therapeutic use
3.
Article
in English
| IMSEAR
| ID: sea-42465