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Arq. neuropsiquiatr ; 67(2b): 428-431, June 2009. ilus, tab
Article in English | LILACS | ID: lil-519270

ABSTRACT

OBJECTIVE: To investigate spectral analysis of electroencephalograms (EEG) for the alpha frequency band during rest and cognitive stimulation in healthy adults and individuals with mild cognitive impairment. METHOD: We analyzed 56 EEGs from 28 patients, 7 men and 21 women, 12 of whom (40 percent) were controls, 16 patients with mild cognitive impairment (60 percent). Ages ranged from 61 to 83 years. All individuals were patients in the Psycho-geriatric Out-patients Clinic of LIM-27, of the Psychiatric Institute of the Clinicas Hospital of the Faculty of Medicine of the University of São Paulo, IPq-HCFMUSP, between 2004 and 2007. Each patient underwent two exams with an interval of at least six months between them. During the exam, performed after a period of wakefulness and rest, the patients memorized series of pictures. RESULTS: Analysis of spectral potential both at rest and during the memorizing task showed no statistical differences between baseline and final recordings. CONCLUSION: Spectral analysis of EEGs showed coherent results with the clinical stability of the patients evaluated but was unable to distinguish between the control group and patients with MCI. Future studies should include a larger sample and a longer follow up.


OBJETIVO: Realizar a análise espectral da banda de frequência alfa do EEG em adultos saudáveis, com comprometimento cognitivo leve (CCL), durante o repouso e a estimulação cognitiva. MÉTODO: Analisamos 56 EEGs de 28 pacientes, 7 homens e 21 mulheres, 12 dos quais (40 por cento) controles, 16 pacientes com CCL (60 por cento), com idades entre 61 a 83 anos.Todos os pacientes foram atendidos no serviço de psicogeriatria do LIM 27, do Instituto de Psiquiatria da Faculdade de Medicina da USP,entre os anos de 2004 a 2007, sendo que cada paciente realizou 2 exames com intervalo de 6 meses entre eles. Os registros dos EEGs foram realizados em repouso e durante a realização de atividade de memorização de figuras. RESULTADOS: A analise espectral durante o repouso e a tarefa de memorização não mostraram diferenças estatísticas entre os EEGs iniciais e finais. CONCLUSÃO: A análise espectral dos EEGs mostrou-se coerente com a estabilidade clínica dos dois grupos, no entanto não foi capaz de distinguir o grupo controle do grupo CCL. Estudos futuros deverão incluir um maior número de indivíduos por um tempo maior de seguimento.


Subject(s)
Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Cognition Disorders/physiopathology , Electroencephalography/methods , Memory, Short-Term/physiology , Alpha Rhythm/methods , Case-Control Studies , Severity of Illness Index
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