Epithelial odontogenic tumors: analysis of 156 cases in a Brazilian population / Tumores odontogénicos epiteliales: análisis de 156 casos en una población brasileña

The objective of this study was to determine the distribution of epithelial odontogenic tumors diagnosed histologically in a period of 41 years in a Brazilian population according to age, gender, site affected and compare these data with previously reported studies from other countries. Data of epithelial odontogenic tumors diagnosed were collected from the files of the Oral Pathology Laboratory of Federal University of Rio Grande do Norte, Natal, RN, Brazil, and entered in a standardized form for later comparisons. Clini-cal features obtained from the patient records and microscope slides were reviewed according to the 1992 World Health Organization classification. A total 156 epithelial odontogenic tumor were reported. Of these, all of them were benign. Ameloblastoma was the most frequent type (85.9 %), followed by adenomatoid odontogenic tumor (10.9 %) and calcifying epithelial odontogenic tumor (3.2 %). The mean age of the patients was 38 years, with a wide range (11­80 years). The posterior region of mandible was the anatomic site most frequently affected by this disease, and no significant differences were found between sexes in the diagnosis of odontogenic tumors. A marked geographic variation in the relative incidences of various epithelial odontogenic tumors was found. It was particularly notable in ameloblastomas and adenomatoid odontogenic tumors, with the incidences observed in the present study being similar, sometimes different to earlier studies in others parts of the world.

El objetivo fue determinar la distribución de los tumores odontogénicos epiteliales diagnosticados histológicamente en un período de 41 años en una población brasileña según edad, sexo y la zona afectada y comparar estos datos con estudios anteriores de otros países. Los datos de los tumores odontogénicos epiteliales diagnosticados fueron obtenidos de los archivos del Laboratorio de Patología Oral de la Universidad Federal de Rio Grande do Norte, Natal, RN, Brasil, e introducidos en un formulario estandarizado para comparaciones futuras. Las características clínicas obtenidas a partir de los registros de los pacientes y los portaobjetos de microscopio fueron revisados de acuerdo a la clasificación de la Organización Mundial de la Salud 1992. Se informó de un total de 156 tumores epiteliales odontogénicas. De estos, todos eran benignos. Ameloblastoma fue el tipo más frecuente (85,9 %), seguido por el tumor odontogénico adenomatoide (10,9 %) y el tumor odontogénico epitelial calcificante (3,2 %). La edad media de los pacientes fue de 38 años, con un rango amplio (11­80 años). La región posterior de la mandíbula era el sitio anatómico más afectado por esta enfermedad, y no se encontraron diferencias significativas entre sexos en el diagnóstico de los tumores odontogénicos. Se encontró una marcada variación geográfica en las incidencias relativas de diversos tumores odontogénicos epiteliales. Fue particularmente notable en ameloblastomas y tumores odontogénicos adenomatoide, con las incidencias observadas en este estudio siendo a veces similares, y a veces diferentes de los estudios anteriores en otras partes del mundo.

Adenomatoid Odontogenic Tumor: A Case Report.

Adenomatoid odontogenic tumor (AOT) is a very rare odontogenic tumor with an incidence of 1%. Overall it accounts for 9% of all odontogenic tumors. In most of the cases, AOT is misdiagnosed as an odontogenic cyst. Younger individuals are commonly affected and particularly in females. AOT is seen predominantly in the maxillary anterior region in association with an unerupted tooth. Permanent dentition is affected more than the deciduous dentition. Intraoral periapical radiographs play a major role in the diagnosis compared to orthopantomogram because of its increased contrast but for the better assessment of the extension of larger lesions orthopantomogram is must. AOT resembles benign odontogenic lesions like dentigerous cyst and tumors like ameloblastoma. The lesions are managed conservatively by surgical excision along with the removal of the affected tooth and have an excellent prognosis.With this background, we report an unusual case of AOT involving maxillary anterior region in 15-year-old male patient. The present article reviews the etiology, clinical features, histopathological features, and treatment modalities of AOT.

Augmentation of residual alveolar bone height with tissue engineering for dental implant placement.

The challenge of correcting deficient vertical alveolar height for dental implant placement has been there since dental implants came in to regular clinical placement. The ability of various methods to increase the residual alveolar height has met with varying results. The primary reason is that the techniques were not quite successful in maintaining the required residual alveolar height. Use of Bone Morphogentic Protein, especially rhBMP-2 has been met with high degree of success in deficient vertical alveolar height in a mandibular ridge. The demonstration of this using a case has been presented here.

Follicular Ameloblastoma: A Case Report.

Ameloblastoma is a true neoplasm of odontogenic origin. It is the most common odontogenic neoplasm, and only odontome out numbers it in reported frequency of occurrence. Th is tumor comprises about 1% of tumors and cysts arising in the jaws. It appears most commonly in the third to fi fth decades and with equal frequency between sexes. Ameloblastoma prevalently occurs in the mandibular molar and ramus areas. Th e patients usually present late after the tumor achieved considerable size to cause facial disfi gurement. Here we present a case of follicular ameloblastoma in a 38-year-old female patient who presented with a swelling on the right side of the mandible.

Concomitant occurrence of cemento-ossifying fibroma and adenomatoid odontogenic tumor with bilateral impacted permanent canines in the mandible.

Adenomatoid odontogenic tumor (AOT) is an uncommon, benign and slow growing odontogenic tumor, which is usually located in an anterior region of the maxilla without pain. Cemento-ossifying fibroma (COF) is a relatively rare benign tumor of the jaw. Here we present 2 lesions presenting in unusual forms, follicular variant of AOT in the mandible and COF associated with impacted canine in the mandible, occurring concomitantly in the same patient. Both lesions presented classic histopathologic features.

Clinicopathological and demographic characteristics of ameloblastomas in a population from Bahia, Brazil / Características clinicopatológicas e demográficas de ameloblastomas em uma população da Bahia, Brasil

Purpose: The present study aimed to review a series of ameloblastoma cases by observing their clinicopathological and demographic characteristics. The data in this study were compared to previous studies. Methods: Seventy ameloblastoma cases were obtained from the archive of the Surgical Pathology Service of the Dental School of the Federal University of Bahia and were analyzed with regards to age, gender, clinical manifestation, radiographic aspect, anatomical distribution and histological subtype. These data were submitted to statistical analysis. Results: Of the 70 cases, 35 (50%) occurred in males and 35 (50%) in females. Young adults were most affected by tumors. Fifty-six (80%) of all tumor cases occurred in the jaw. The main histological subtype seen was unicystic ameloblastoma, which occurred in 35 cases. The majority of the tumors [n=57 (81.4%)] were treated with radical surgery. The differences in clinical aspects and anatomical distribution were shown to be statistically significant (P<0.001).Conclusion: The clinical-epidemiological profile of the patients in the present study is similar to that in other populations, with unicystic ameloblastoma being the most common histological subtype seen.

Objetivo: O presente estudo se propôs a revisar uma série de casos de ameloblastomas, observando-se as suas características clinicopatológicas e demográficas. Adicionalmente, os dados foram comparados com estudos prévios.Metodologia: Setenta casos de ameloblastomas foram recuperados dos arquivos do serviço de Patologia Cirúrgica da Faculdade de Odontologia da Universidade Federal da Bahia e analisados quanto a idade, sexo, manifestação clínica, aspecto radiográfico, distribuição anatômica e subtipo histológico. Esses dados foram submetidos à análise estatística.Resultados: Dos 70 casos, 35 (50%) acometeram o sexo masculino e 35 (50%) o sexo feminino. Os adultos jovens foram os mais afetados pelos tumores. A mandíbula foi o sítio preferencial, correspondendo a 56 casos (80%) do total dos tumores analisados. O principal subtipo histológico encontrado foi o ameloblastoma unicístico, que acorreu em 35 casos. A maioria dos tumores [n=57 (81,4%)] foi tratada cirurgicamente de forma radical. Dados em relação ao aspecto clínico e distribuição anatômica apresentaram-se estatisticamente significantes (P<0,001). Conclusão: O perfil clínico- epidemiológico dos pacientes do presente estudo é similar ao de outras populações, sendo que o ameloblastoma unicístico é o subtipo histológico mais comum em nossa população.

Ameloblastoma: revisión de la literatura / Ameloblastoma: literature review

El ameloblastoma es una neoplasia benigna polimórfica localmente invasiva constituida por una proliferación de epitelio odontogénico en un estroma fibroso, que se clasifica dentro de los tumores benignos de epitelio odontogénico con estroma fibroso maduro sin ectomesénquima odontogénico. Representa entre el 11 y 13 por ciento de todos los tumores odontogénicos. Se manifiesta prevalentemente durante la cuarta y quinta décadas de vida, sin predilección por el sexo. Puede presentarse a cualquier edad, mas la mayor incidencia es entre los 20 y 50 años salvo la variedad uniquística que se diagnostica generalmente entre los 20 y 30. Este tumor crece lentamente y de forma silente, sin signos precoces evidentes, afectando fundamentalmente el hueso mandibular. La actitud terapéutica es compleja por su propensión característica a la recidiva, que surge de la posibilidad de dejar lesiones microscópicas periféricas y de la eventualidad de un origen pluricéntrico del tumor.

The ameloblastoma is a locally invasive polymorphic benign neoplasm composed of a proliferation of odontogenic epithelium in a fibrous stroma, classified within the benign tumors of above mentioned epithelium with a mature stroma without odontogenic ectomesenchyme. It represents the 11 and the 13 percent of all odontogenic tumors. Its appearance is mainly during the fourth and fifth decade of life in any sex and in any age with a greater incidence between 20 and 50 years except the unicystic variety diagnosed between 20 and 30 years. This tumor has a lengthy and silent growth without obvious early sings, involving mainly the mandibular bone. Its therapeutical behavior is complex due to its propensity characteristic to relapse caused by the possible presence of peripheral microscopic lesions and by the multicentric origin of tumor.

Estudo retrospectivo dos casos diagnosticados como ameloblastoma no Serviço de Anatomia Patológica do Hospital Universitário Antônio Pedro entre 1997 e 2007 / A retrospective study of ameloblastoma in the Anatomic Pathology Service of Antônio Pedro University Hospital between 1997 and 2007

INTRODUÇÃO: O ameloblastoma é um tumor odontogênico de origem epitelial que, pela freqüência, subtipos clínicos, grande capacidade infiltrativa e alta tendência à recorrência tem merecido bastante atenção. OBJETIVO:Realizar estudo retrospectivo dos casos diagnosticados histopatologicamente de ameloblastoma no Serviço de Anatomia Patológica do Hospital Universitário Antônio Pedro da Universidade Federal Fluminense (HUAP/UFF) no período de 1997 a 2007. Material e métodos: Foram selecionados casos de ameloblastoma correspondentes ao período da pesquisa, e dados como idade, sexo, raça, localização da lesão, aspecto radiográfico, tipo de biópsia, diagnósticos clínico e histopatológico foram compilados das fichas de requisição e/ou prontuários. RESULTADOS:Depois do levantamento e da revisão das lâminas para confirmação do diagnóstico de ameloblastoma, a amostra totalizada foi de 23 casos. Os pacientes mais acometidos eram do sexo masculino, leucodermas e estavam entre a primeira e a terceira década de vida. Todos os casos ocorreram na mandíbula, sendo a região posterior a mais afetada. Predominaram o aspecto radiográfico multilocular e, histopatologicamente, o padrão multicístico, sendo os subtipos folicular e híbrido os mais freqüentes. Não foram observados casos de ameloblastoma desmoplásico e de células basais. CONCLUSÕES: A freqüência do ameloblastoma varia de acordo com a região geográfica avaliada, e a realização de estudos retrospectivos pode contribuir para a identificação de grupos e dos possíveis fatores associados ao seu desenvolvimento.

BACKGROUND: Ameloblastoma is an odontogenic tumor of epithelial origin that has received considerable attention due to its frequency, clinical subtypes and high tendency to infiltrate and recur. OBJECTIVE: To perform a retrospective study of cases histopathologically diagnosed of ameloblastoma at the Pathological Anatomy Department of APUH/UFF-RJ from 1997 to 2007. Material and methods: We selected cases of ameloblastoma corresponding to the period of this research. Data such as age, gender, race, location of lesion, radiographic features, type of biopsy, clinical diagnosis, and histopathological diagnosis were compiled from patients' records. RESULTS:After the investigation and review of slides for confirmation of the diagnosis of ameloblastoma, the sample comprised 23 cases. Most patients with ameloblastoma were male, Caucasian and age range 10-30. All lesions were in the mandible, mainly in the posterior region. The multilocular radiographic types were predominant, and histopathologically, multicystic type, whereas the follicular and hybrid ones were more frequent. There were no cases of desmoplastic and basal cells ameloblastoma. CONCLUSIONS:The frequency of ameloblastoma varies according to geographic analyzed region, and retrospective studies can contribute to identify groups and possible factors associated with its development.

Tumores odontogênicos: estudo clínico-patológico de 238 casos / Odontogenic tumors: clinical and pathology study of 238 cases

Os tumores odontogênicos são neoplasias que se desenvolvem exclusivamente nos ossos gnáticos, originando-se dos tecidos odontogênicos por proliferação de tecido epitelial, mesenquimal ou ambos. OBJETIVO: Avaliar a incidência de tumores odontogênicos em determinada instituição e comparar com outros estudos da literatura mundial. FORMA DE ESTUDO: Estudo de coorte transversal. MATERIAL E MÉTODO: O material do estudo foi levantado a partir dos registros de pacientes com tumores odontogênicos, no período de janeiro de 1992 a março de 2007 (15 anos). Foram incluídos os casos de pacientes que se enquadravam na Classificação Histológica da Organização Mundial de Saúde (OMS) de 2005. Foram analisados os indicadores gênero, faixa etária, localização anatômica, tipo histológico e presença de sintomatologia. RESULTADOS: Os tumores odontogênicos constituíram 4,76 por cento dentre todas as lesões biopsiadas dentro do período estudado. A idade média dos pacientes foi de 30,7 anos, 57 por cento dos pacientes eram do gênero masculino. O tumor odontogênico ceratocístico foi o tipo histológico mais prevalente (30 por cento), seguido do ameloblastoma (23,7 por cento). Quanto à presença de sintomatologia, 75,7 por cento dos casos apresentaram-se assintomáticos. CONCLUSÃO: Os tumores odontogênicos parecem ter discreta predileção pelo gênero feminino, segunda e terceira décadas de vida, sendo mais freqüentes na mandíbula e, na maioria dos casos apresentam-se assintomáticos.

Odontogenic tumors are neoplasms that develops exclusively in the gnathic bones; they originate from odontogenic tissues, by epithelial or mesenchymal proliferation, or both. AIM: To evaluate the incidence of odontogenic tumors in a specific institution, and to compare these findings with other studies in the literature. STUDY FORMAT: A cross-sectional cohort retrospective study. MATERIAL AND METHOD: The sample was obtained from the files of patients with odontogenic tumors diagnosed between January 1992 and March 2007 (15 years). Cases in which the diagnosis could be adapted to the new World Health Organization (WHO) of 2005 were included. Data such as gender, age, anatomical site, histological type and symptomatology were analyzed. RESULTS: Odontogenic tumors were 4.76 percent of all biopsied lesions within the studied period. The mean age was 30.7 years; 57 percent of the patients were male. The keratocystic odontogenic tumor was the most prevalent histological type (30 percent), followed by the ameloblastoma (23,7 percent). The rate of asymptomatic cases was 75.7 percent. CONCLUSION: Odontogenic tumors occurred more frequently in females, in the second and third decades of life, and more commonly in the mandible; most cases were asymptomatic.

Ameloblastoma: Estudo Clínico-Histopatológico / Ameloblastoma: a clinical-histopathological study

O ameloblastoma constitui uma neoplasia intra-óssea de grande interesse, devido à freqüência com que é relatada em diversos estudos e à capacidade que possui em invadir agressivamente a região maxilofacial, podendo deixar seqüelas mutilantes e, até mesmo, colocar em risco a vida dos pacientes. O objetivo do presente trabalho busca analisar as características clínico-histopatológicas dos casos de ameloblastomas ocorridos no estágio diagnóstico avançado clínico e histopatológico das doenças de boca da Faculdade de Odontologia Prof. Albino Coimbra Filho (FAODO/UFMS) entre o período de 1999 a 2007. Foram encontrados 18 casos, nos quais verificou-se uma leve tendência para o gênero feminino (55,6%); a faixa etária mais acometida variou entre 20-50 anos (72,2%), e o tipo clínico mais freqüente foi o multicístico (72,2%). O aspecto radiográfico multilocular foi o mais encontrado (81,3%); a localização preponderante, a mandíbula, o tipo histopatológico predominante, o folicular, e o tratamento de eleição, a ressecção cirúrgica radical para quase a totalidade dos casos. O conhecimento deste tumor é de fundamental importância para a determinação do tipo de tratamento. Diante desta realidade e frente aos desafios que a clínica odontológica oferece, é importante que os cirurgiões-dentistas estejam preparados para reconhecer o ameloblastoma, caso haja suspeita da lesão

Estudo clínico, radiográfico, microscópico e perfil imunoistoquímico dos ameloblastomas: a experiência do Hospital A. C. Camargo / Clinico radiographic, histologic and immunohistochemical study of ameloblastomas: the A. C. Camargo Hospital experience

Os Ameloblastomas são tumores odontogênicos que exibem crescimento lento, porém mostram-se localmente agressivos. Este estudo teve como objetivo avaliar e correlacionar os achados clínico-radiográficos, histopatológicos e a expressão imunoistoquímica de diversos marcadores em Ameloblastomas e estabelecer informações relevantes quanto biologia, tratamento e prognóstico deste tumor. ... Os dados foram analisados estatisticamente usando os testes estatísticos apropriados, dentre eles o método de Kaplan-Meyer e a regressão logística de Cox. ... A análise estatística univariada mostrou que o aspecto radiográfico multilocular, a presença de corticais ósseas rompidas e o aspecto histológico folicular indicaram maior chance de recorrência. ... Podemos concluir que o ameloblastoma mostrou distribuição semelhante entre os gêneros, predominância na quarta e quinta décadas de vida na região posterior de mandíbula. O padrão sólido foi o mais comum e radiograficamente estes casos exibiram predominantemente o padrão multilocular com aumento estatisticamente significativo na incidência de rescidivas quando comparado aos casos sólidos uniloculares. A presença de cortical mandibular perfurada também indicou um maior risco para a recorrência (6,5 vezes). O epitélio dos ameblastomas foi itensamente positivo para as citoqueratinas AE1AE3, 34β12, 14 e 19. O tempo de queixa com positividade para Syndecan-1 foi estatisticamente menor do que os casos negativos. Além disso, os ameloblastomas mostram imunopositividade para EGFr e PTHrP.

Ameloblastomas are benign odontogenic tumors that exhibit slow growth, but have shown to be locally aggressive. The aim of this study was to evaluate and correlate the clinical-radiographic, histopathologic findings and immunohistochemical expression of various markers in Ameloblastomas and establish relevant information regarding biology, treatment and prognosis of this tumor. This was a retrospective study of 121 cases of Ameloblastomas diagnosed and treated at the "Hospital A.C.Camargo" between 1953 and 2003. All cases were confirmed histologically, classified and a selection of areas for the Tissue Microarray were done. Antibodies were analyzed to investigate prognostic and cell proliferation factors, (anti Ki-67; p53, EGFR, Syndecan-1 (CD 138), PTHrP) and to investigate the tumoral histogenesis (vimentin and cytokeratins Ck 1, 4, 6, 7, 8, 10, 14, 16, 18, 19 and 34ß andAE1/AE3). The data ere statistically analyzed using the appropriate statistical tests, among them twhe Kaplaars) n-Meyer method and Cox logistic regression. Patients' ages ranged from 02 to 82 years (mean = 33.2 ye with slight predilection for females. The majority of cases affected the posterior region of the mandible (80%) Radiographically, 60% showed multilocular pattern. Solid Ameloblastomas accounted for 113 cases, and the plexiform histologic type was the commonest. Solid tumors were treated by resection in block, curettage associated with cryotherapy, or only curettage, and unicystic tumors only by conservative procedures. The global recurrence rate was 22.1% with a mean follow-up time of 9.7 years. Univariate statistical analysis showed that the radiographic multilocular aspect, presence of ruptured bone corticals and the follicular histologic aspect indicated greater chance of recurrence. Positivity for cytokeratins AE1/AE3, 34ß12, 14 and 19 and negativity for cytokeratins 1 and 10 strengthened their odontogenic profile. The innumerable histologic subtypes and great variability of cellular differentiation in each tumor makes some cytokeratins, such as CKs 6,7, 8, 16 and 18 and vimentin show focal and specific expressions. Syndecan-1 howed negativity for 18.2% and weak positivity for 42.1% weak positivity for it. In the evaluation for Ki67, the majority of the samples of the cases. It showed statistically significant association with the time of complaint, in other words, cases positive for this marker showed a shorter time of complaint than the cases in which Syndecan-1 was negative. EGFR was expressed in the majority of cases, irrespective of the histologic subtype, but showed no association with any clinical and radiographic parameter. PTHrP showed 100% positivity in our casuistic and statistical analysis showed that patients with strong positivity for this marker were at an older age than patients with presented marking between 0-25% of tumoral cells. The marker p53 showed positivity in 82.5% of the cases and of these, 40.7% with immunoreactivity between 51-100% of the tumoral cells. In conclusion, ameloblastoma showed similar gender distribuition, most of the cases occured in the fourth and fifth decades and the majority affected the posterior region of the mandible.The solid pattern was the most common and, radiographically those cases were predominantely multilocular. The multilocular pattern showed a statistically higher tendendy to recurrence when compared to the solid unilocular type. Moreover, a perforated osseous cortical increased 6.5X the chance for recurrence. Tipically, the Ameloblastoma epithelium was positive for citokeratins AE1AE3, 34ß12, 14 and 19. The time of complain for the positives cases of Syndecan-1 were statistically lower when compared to the negative cases and solid ameloblastomas were positive for EGFr and PTHrP.

A new radiological classification for ameloblastoma based on analysis of 19 cases / Nueva Clasificación Radiológica del Ameloblastoma Basada en el Análisis de 19 Casos

OBJECTIVE: To describe ameloblastoma of the jawbone in young Jamaicans, with special emphasis on radiological findings, and to introduce a radiological classification which could assist in the categorization of these cases according to their biological behaviour and hence their subsequent surgical and medical management. SUBJECTS AND METHODS: The series comprised all the 18 cases of ameloblastoma of the jaw seen in patients under the age of 20 years in the two major hospitals in Jamaica with an oral and maxillofacial surgery department from 1980 to 1995. Radiological and histological diagnosis was confirmed in all. A case of maxillary ameloblastoma in a 13-year old girl seen in the year 2000 was also included in this study. This last case had special attributes. RESULTS: All 19 patients had primary lesions of ameloblastoma. The mean age was 16.1 years with a mode of 18 years and a range of 13 to 19 years. The male to female ratio was 1.1:1. Eighteen cases were seen in the mandible and one case in the maxilla. Of these, 42were unilocular and 58were multilocular radiologically. Thirty-two per cent of cases had unerupted teeth associated with the lesions and 32had root resorption. Based on our new radiological classification, the most predominant radiological type was IIb2 with root resorption (42). There was no radiological type classically simulating dentigerous cyst (Ia2). CONCLUSION: Ameloblastoma in young Jamaicans presented more in the adolescent period and are predominantly unicystic and rare in the maxilla. A new classification for ameloblastoma based solely on radiological presentation is adopted.

Estudo dos casos de ameloblastomas diagnosticados no Laboratorio de Patologia Bucal da Faculdade de Odontologia da Universidade Federal do Rio Grande do Sul / Study of ameloblastoma's cases diagnosed in the Oral Pathology Laboratory of the Faculty of Dentistry of the Federal University of Rio Grande do Sul

Com o objetivo de obter um perfil de indivíduos afetados por ameloblastoma e comparar os resultados com os estudos encontrados na literatura, realizou-se uma análise retrospectiva dos casos de ameloblastomas do Laboratório de Patologia Bucal da FO-UFRGS. Os resultados revelaram uma maior ocorrência em indivíduos jovens, do sexo feminino, raça branca, localização predominantemente na mandíbula e tipo histológico plexiforme. Conclui-se que, o perfil dos pacientes com ameloblastoma diagnosticados no Laboratório de Patologia Bucal da FO-UFRGS concorda com o perfil de pacientes com ameloblastoma diagnosticado em outras partes do mundo e relatado na literatura diferindo apenas no que se refere a faixa etária no momento do diagnóstico

Aspectos dos ameloblastomas intra-ósseos da mandíbula na radiologia convencional / Radiographic findings of mandibular intraosseous ameloblastomas

OBJETIVO: Determinar a prevalência do ameloblastoma intra-ósseo da mandíbula em relação ao sexo e à idade dos pacientes, as suas localizações mais freqüentes e os achados radiológicos mais comuns. MATERIAL E MÉTODO: Foram revisados 31 casos de ameloblastomas intra-ósseos da mandíbula diagnosticados no Serviço de Cirurgia Oral e Maxilofacial do Hospital Universitário Pedro Ernesto, no período de janeiro de 1990 a dezembro de 1999. Os prontuários e as radiografias foram revisados por um único examinador. RESULTADOS: Houve ligeira predominância do sexo feminino e a média da idade dos pacientes foi de 35,2 anos. A maioria dos pacientes apresentava aumento de volume devido ao crescimento da lesão, e alguns deles relatavam sintomas dolorosos. Quanto aos aspectos radiológicos, todas as lesões eram exclusivamente radiotransparentes, sendo que 61,3 por cento eram multiloculadas e 38,7 por cento, uniloculadas. Os limites radiográficos eram nítidos e bem delimitados em 77,4 por cento dos casos e a maioria das lesões causava expansão nas corticais ósseas vestibular e lingual da mandíbula. Quarenta e dois por cento das lesões causavam deslocamento de elementos dentários adjacentes à lesão e em 25,8 por cento dos casos havia associação do tumor com dente incluso. CONCLUSÃO: Não houve diferenças estatisticamente significativas entre pacientes com lesões com aspecto radiológico uniloculado e multiloculado, quando foram analisados a expansão das corticais ósseas, os limites radiográficos, a associação da lesão com a coroa de um dente incluso, o deslocamento dentário e a reabsorção das raízes dentárias.

Fibroma ameloblástico / Ameloblastic fibroma

Las causas de la retención dentaria, asociadas con tumefacción facial, suelen ser muchas y muy variadas. Dentro de las mismas, las causas tumorales no son ltan tenidas en cuenta como debieran. Es por ello, que decidimos llamar la atención a este respecto y presentar este caso de retención dentaria y deformidad facial debido a un fibroma ameloblástico

Tumores odontogénicos en Puebla / Odontogenic tumors in Puebla

Los tumores de origen odontogénico representan un conjunto de entidades patológicas exclusivas de los huesos de la región maxilomandibular. La importancia de su diagnóstico clínico, radiográfico y microscópico radica en las serias implicaciones de su tratamiento y pronóstico. Se presenta un estudio retrospectivo sobre estas entidades a partir del análisis de 2.859 biopsias vistas en la Unidad de Diagnóstico de la ciudad de Puebla, México. En el presente estudio, estas entidades representaron el 0.24 por ciento, siendo el ameloblastoma de tipo quístico la lesión más frecuentemente hallada y representó el 57.1 por ciento de los tumores odontogénicos estudiados. Se discuten los aspectos antomoclínicos, de tratamiento y pronóstico y se hace énfasis en la importancia del diagnóstico preciso para estas lesiones, ya que como se reporta en la literatura, este grupo de entidades tienden a producir una gran destrucción del hueso y presentan complicaciones importantes

Ameloblastoma--a clinical study of 13 cases.

Ameloblastoma is commonly encountered odontogenic tumour in Bangladesh. A clinical assessment of this tumour is presented in this paper with the particular attention to its age, and sex incidence, clinical presentation, and its management. Complete removal of the neoplasm is the treatment of choice regardless the method of accomplishment to obtain complete cure. Small lesion, particularly in young patients may by given chance to be managed by enucleation and curettage exposing the healthy surrounding tissue. However radical resection of the tumour is the most efficient treatment particularly in large tumours to avoid recurrence.

Ameloblastomas de los maxilares. Revision de la literatura análisis epidemiológico y estudio histopatológico (Venezuela) / Ameloblastomas of the maxillary literature. Review, epidemiological analysis, histopathologic study (Venezuela)

Revisión completa de la literatura de los ameloblastomas de los maxilares; estudio epidemiológico de estos casos a nivel del laboratorio Central de Histopatología Bucal Dr. Pedro José Tinoco S. Facultad de Odontología de la U.C.V. Análisis comparativo de los datos internacionales y nacionales esta materia, su clasificación en base al aspecto histopatológico y sus posibles tratamientos