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Rev. méd. Chile ; 147(3): 390-394, mar. 2019. graf
Article in Spanish | LILACS | ID: biblio-1004362

ABSTRACT

Goodpasture Syndrome is described as a single episode disease entity. It is diagnosed with the demonstration of antiglomerular basement (anti-GBM) antibodies in plasma or renal tissue. Although the recurrence of anti-GBM disease is rare, it has been reported in up to 3% of cases. Recurrence with negative anti-GBM antibodies in plasma is even less frequent We report a 63 years old male in whom anti-GBM disease recurred without detectable anti-GBM antibodies in plasma, despite having positive antibodies at the onset.


Subject(s)
Humans , Male , Middle Aged , Autoantibodies/analysis , Anti-Glomerular Basement Membrane Disease/pathology , Recurrence , Biopsy , Prednisone/therapeutic use , Trimethoprim, Sulfamethoxazole Drug Combination/therapeutic use , Fluorescent Antibody Technique , Anti-Glomerular Basement Membrane Disease/drug therapy , Anti-Glomerular Basement Membrane Disease/diagnostic imaging , Cyclophosphamide/therapeutic use , Kidney Diseases/pathology , Kidney Glomerulus/pathology , Anti-Bacterial Agents/therapeutic use
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