ABSTRACT
Resumen Objetivo: Describir la experiencia en cirugía electiva de condilomas anales en pacientes mayores de 15 años en un hospital terciario de la Región Metropolitana. Material y Método: Estudio observacional retrospectivo y descriptivo, en el cual se analizan las intervenciones quirúrgicas electivas realizadas entre 2008 a 2021. Resultados: Dentro del período analizado se obtuvo 165 cirugías de condilomas anales, lo que corresponde a 137 pacientes en total. El 85% de los pacientes son de sexo masculino, el 68% de los pacientes son VIH positivo, un 87% de los pacientes MSM (hombres que tienen sexo con otros hombres) son VIH positivo, el 34% de los pacientes tiene antecedente de ETS, el 46% de los pacientes recibió terapia tópica como tratamiento preoperatorio o posoperatorio. Un 25% de los pacientes presenta recidiva en su historia personal, un 21% de los pacientes presenta lesiones anales intraepiteliales de alto grado, un 6% presenta carcinoma escamoso infiltrante. No hubo mortalidad descrita. Discusión: El presente estudio, describe la experiencia en cirugía de condilomas de un hospital terciario de la Región Metropolitana de Chile, cuya población corresponde a un estrato socioeconómico medio y bajo. Se logra describir a la población que es intervenida de condilomas acuminados, además de sus resultados quirúrgicos precoces y a largo plazo. Conclusión: El presente estudio, presenta una población de 137 pacientes operados de condilomas anales, a partir de los hallazgos de la cirugía. Se cumple el objetivo del estudio de caracterizar en un período de 12 años los resultados quirúrgicos de dicha serie, algo no reportado previamente en la literatura chilena.
Objective: To describe the experience in elective surgery for anal condylomas in patients over 15 years of age in a tertiary hospital in the Metropolitan Region. Materials and Method: Retrospective and descriptive observational study about elective surgical interventions performed between 2008 to 2021. Results: Within the analyzed period, 165 anal warts surgeries were obtained, corresponding to 137 patients. 85% of the patients are male, 68% are HIV positive, 87% of the MSM patients are HIV positive, 34% of the patients have a history of STDs, 46% of the patients received topical therapy as preoperative or postoperative treatment. 25% present recurrence in their personal history, 21% present high-grade anal intraepithelial lesions, 6% present infiltrating squamous carcinoma. There was no reported mortality. Discussion: The present study describes the experience in condyloma surgery in a tertiary hospital in the Metropolitan Region of Chile, whose population corresponds to a medium and low socioeconomic stratum. It is possible to describe the population that undergoes surgery for this reason, in addition to its early and long-term surgical results. Conclusion: The present study presents a population of 137 patients operated on for anal condylomas, based on the findings of the surgery. The objective of the study to characterize the surgical results of this series over a 12-year period is fulfilled, something not previously reported in the Chilean literature.
Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Aged , Anus Diseases/therapy , Condylomata Acuminata/therapy , Antiviral Agents/therapeutic use , Anus Diseases/surgery , Anus Diseases/drug therapy , Papillomaviridae , Condylomata Acuminata/surgery , Condylomata Acuminata/drug therapy , Demography , Retrospective Studies , Papillomavirus Infections/therapy , Kaplan-Meier Estimate , Aminoquinolines/therapeutic useABSTRACT
La tuberculosis (TBC) es una enfermedad crónica transmisible, causada por el bacilo de Koch (Mycobacterium Tuberculosis). La forma extrapulmonar se presenta en el 5-15 por ciento de los casos. En la región anal en forma de ulceraciones, lesiones hipertróficas, fístulas, fisuras y abscesos perianales. Los autores relatan 4 casos de tuberculosis ano-recto-perineal. Haciendo énfasis en el diagnóstico precoz y en la capacidad del médico para comprometer al paciente para completar su tratamiento.
Tuberculosis is an infectious chronic disease, caused by Mycobacterium tuberculosis. Extrapulmonary disease accounts for 5 to 15 per cent of all cases. The disease might be presented as ulcers, hyperthrophic lesions, fistula, fissures and perianal abscesses. The authors refer to 4 cases of perianal tuberculosis. Emphasizing in sudden diagnosis and in the ability of the physician to compromise patients in order to fulfill their treatment.
Subject(s)
Humans , Male , Adult , Female , Middle Aged , Anus Diseases/diagnosis , Anus Diseases/drug therapy , Perineum/pathology , Tuberculosis/diagnosis , Tuberculosis/drug therapy , Antitubercular Agents/administration & dosage , Biopsy , Early DiagnosisABSTRACT
Antecedentes: La infección persistente por VPH de alto riesgo se asocia con cáncer cervicouterino, encontrándosepositividad en el 99,7% de los casos. Las verrugas anogenitales son una forma de presentación de la infección persistente. Objetivo: Investigar la eficacia y seguridad de imiquimod en crema al 5%, en el tratamiento de las verrugas anogenitales en mujeres. Método: Estudio prospectivo no randomizado, en mujeres portadoras de verrugas anogenitales asociadas a VPH. El tratamiento consiste en la autoaplicación de imiquiomod en crema al 5% tres veces a la semana por hasta un período de 16 semanas. Se define como respuesta completa al tratamiento aquella en que desaparece completamente la lesión; por respuesta parcial la disminución de al menos un 50% del volumen inicial de la lesión. Resultados: Durante un período de 8 meses fueron ingresadas y tratadas 38 pacientes La duración del tratamiento varió entre 1 y 4 meses. El número promedio de aplicaciones fue de 28,7. El 66% (25 casos) de las pacientes presentaron una respuesta completa, en tres casos no hubo respuesta, uno de ellos en una paciente inmunodeprimida, en 10 casos hubo respuestas parciales. En las pacientes con respuestas completas se necesitó un promedio de 28,7 aplicaciones hasta obtener el resultado. Conclusiones: Imiquimod es un fármaco con buena efectividad y seguridad en el tratamiento de las verrugas anogenitales asociadas a VPH, en tratamiento de tres veces por semana durante mínimo de 10 semanas.
Background: The chronic infection by high-risk HPV serotypes is strongly associated with cervical cancer, detection of HPV on tissue sample has been reported 99.7% of cases. The anal-genital warts represent the clinical manifestation of the persistent infection by this virus. Objectives: To investigate the efficacy and safety of Imiquimod cream 5% concentration, in the treatment of anal-genital warts in women. Methods: A non-randomized prospective study in women diagnosed with anal-genital warts HPV associated. The treatment consists in self-application of imiquimod cream 5%, three times a week for a period of 16 weeks or more. We define complete response to treatment in those patients where the lesion disappeared completely, and partial response to those where the lesion declined at least 50% of its initial volume. Results: Over a period of 8 months were admitted to the study and treated a total of 38 patients. Treatment duration varied between 1 and 4 months. The average number of applications was 28.7 times. 66% (25 cases) of the patients had a complete response, in three cases there was no response, one of them was an immunodepressed patients, in 10 cases there was partial response. The patients with complete response needed an average of 28.7 applications to get that result. Conclusions: Imiquimod is a drug with high effectiveness and safety in the treatment of anal-genital warts HPV associated, in a three times per week and at least 10 weeks total duration treatment.
Subject(s)
Humans , Female , Adolescent , Adult , Middle Aged , Adjuvants, Immunologic/administration & dosage , Aminoquinolines/administration & dosage , Genital Diseases, Female/drug therapy , Anus Diseases/drug therapy , Papillomavirus Infections/drug therapy , Genital Diseases, Female/virology , Anus Diseases/virology , Prospective Studies , Treatment Outcome , Warts/drug therapyABSTRACT
Protozoan infections of the skin, particularly cutaneous amoebiasis, are rare in HIV-positive patients. We report a case of amoebiasis cutis in an HIV-positive truck driver with a history of frequent unprotected sexual exposures. He presented with multiple painful ulcers and sinuses with purulent discharge, necrotic slough and scarring in the perianal and gluteal region for the last 2 years. He was positive for HIV-1 and -2. Cutaneous biopsy revealed numerous Entamoeba histolytica in the trophozoite form, in addition to an inflammatory infiltrate and necrotic debris. He responded well to oral metronidazole and chloroquine. Amoebiasis cutis should be considered in the differential diagnosis of perianal ulcers, particularly in HIV-positive patients.
Subject(s)
Adult , Amebiasis/drug therapy , Amebicides/therapeutic use , Animals , Antiprotozoal Agents/therapeutic use , Anus Diseases/drug therapy , Chloroquine/therapeutic use , Entamoeba histolytica/pathogenicity , Entamoebiasis/drug therapy , Humans , Male , Metronidazole/therapeutic use , Treatment Outcome , Ulcer/drug therapySubject(s)
Humans , Anus Diseases/complications , Anus Diseases/drug therapy , Anus Diseases/prevention & control , Rectal Diseases/drug therapy , Rectal Diseases/etiology , Rectal Diseases/prevention & control , Sexually Transmitted Diseases/drug therapy , Sexually Transmitted Diseases/prevention & control , Acquired Immunodeficiency Syndrome/complications , Anus Neoplasms/complications , Anus Neoplasms/mortality , Diagnosis, Differential , Quality of Life , Risk Groups , Sexual BehaviorABSTRACT
Relato de um caso de condiloma acuminado perianal em uma criança de 18 meses de idade sem história de contato sexual.
Subject(s)
Humans , Female , Infant , Condylomata Acuminata/diagnosis , Anus Diseases/diagnosis , Condylomata Acuminata/drug therapy , Anus Diseases/drug therapyABSTRACT
Se estudiaron 62 pacientes con patología anorrectal y cuadros postquirúrgicos, divididos en 3 grupos de l,2 y 3 semanas de tratamiento con una nueva pomada antiinflamatoria cicatrizante y analgésica de superficie, e se dan a conocer los resultados obtenidos