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Rev. chil. infectol ; Rev. chil. infectol;24(4): 313-318, ago. 2007. ilus
Article in Spanish | LILACS | ID: lil-459596

ABSTRACT

Metapneumovirus humano (MPVh), agente de infección respiratoria aguda baja (IRAB) recientemente descrito, ha sido detectado en 5,4 por ciento de lactantes chilenos hospitalizados por IRAB, con estudio negativo para virus respiratorio sincicial, adenovirus, parain-fluenza e influenza. Puede determinar bronquiolitis o neumonía en hospitalizados, en ocasiones llega a requerir conexión a ventilación mecánica y tratamiento en una unidad de cuidados intensivos. En algunos casos se presenta como apnea, situación que es más frecuente en prematuros. Está descrita su transmisión nosocomial. Presentamos el caso de un lactante de un mes de edad, con apnea, antecedente de prematurez e infección por MPVh y una probable adquisición intrahospitalaria. Se revisan las características clínicas de la infección por este agente y se discute la asociación con apnea e infección nosocomial. El MPVh debiera ser incluido en el estudio etiológico de lactantes que presentan apnea con estudio viral convencional negativo y como agente respiratorio de infección nosocomial


Human metapneumovirus (hMPV), a recently described pathogen of lower respiratory tract infections (LRTI), has been detected in 5,4 percent of Chilean infants hospitalized for LRTI whom are negative for adenovirus, respiratory syncytial virus, influenza and parainfluenza viruses. hMPV may cause bronchiolitis or pneumonia in hospitalized patients, and ocassionally require admission to intensive care units and mechanical ventilation. The infection has been associated with apnea, especially in preterm infants. Nosocomial dissemination has also been described. We present the case of a one-month-of age premature infant with apnea, and infection caused by hMPV of probable nosocomial aquisition. Clinical features of hMPV infection are reviewed and its association with apnea and nosocomial transmission is discussed. hMPV should be included in the routine diagnosis of respiratory viruses in infants with apnea and should be considered among the respiratory pathogens associated with nosocomial transmission


Subject(s)
Humans , Infant , Male , Apnea/virology , Cross Infection/virology , Metapneumovirus/isolation & purification , Paramyxoviridae Infections/complications , Respiratory Tract Infections/virology , Paramyxoviridae Infections/diagnosis , Paramyxoviridae Infections/drug therapy , Respiratory Tract Infections/diagnosis , Respiratory Tract Infections/drug therapy
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