ABSTRACT
Abstract: Zoon's plasma cell balanitis is a chronic genital inflammatory dermatosis that affects uncircumcised men, especially the elderly. It's characterized by painless erythematous plaques of orange hue, located on the glans penis and foreskin. Circumcision is the most effective treatment; however, it can be hard for patients to accept. As an alternative, topical calcineurin inhibitors are used, with good response. This article reports the case of a 32-year-old patient, HIV carrier, diagnosed with Zoon's plasma cell balanitis. Treatment with topical tacrolimus was administered, without improvement. A 6-week course of thalidomide resulted in complete remission of the lesions, without recurrence after eight months of follow-up.
Subject(s)
Humans , Male , Adult , Plasma Cells/pathology , Thalidomide/therapeutic use , Balanitis/drug therapy , AIDS-Related Opportunistic Infections/drug therapy , Balanitis/pathology , Treatment Outcome , AIDS-Related Opportunistic Infections/pathologySubject(s)
Humans , Male , Adult , Balanitis/diagnosis , Balanitis/pathology , Balanitis/therapy , Cryotherapy , Diagnosis, DifferentialABSTRACT
La balanitis de células plasmáticas o balanitis de Zoon, es una dermatosis inflamatoria del pene, de tipo plasmocelular circunscrita, curso crónico recurrente y etiología idiopática, más frecuente en varones adultos mayores, que por su presentación se puede confundir con la eritroplasia de Queyrat. Se presenta el caso de un paciente varón de 82 años con tiempo de enfermedad de 8 años que acude a consulta por presentar lesiones eritematosas granulomatosas, ulceradas y sangrantes en área prepucial. Se realiza biopsia donde se observa adelgazamiento de la epidermis, con ausencia de las capas granular y córnea, y presencia de infiltrado en banda de células plasmáticas. Se confirma el diagnóstico de balanitis plasmocitaria de Zoon y se inicia tratamiento con tacrolimús 0,1 %,fluconazol y econazol con buena respuesta al tratamiento.
Zoon 's balanitis or plasma cell balanitis is an inflammatory dermatosis of penis, type circunscripta plasmocellular, recurrent, chronic course and idiopathic etiology, more frequent in older adult males, which can be confused with the erythroplasia of Queyrat for his presentation. The case of a male patient of 82 years with disease 8 years duration that presented erythematous granulomatous lesions, ulcerated and bleeding in the preputial area is presented. Biopsy showing thinning of the epidermis, is performed with the absence of layers granular and cornea, and presence of band of plasma cell infiltrate. The diagnosis of plasmocytaria Zoon balanitis was confirmed and treatment with tacrolimus 0,1 %,fluconazole and econazole was iniciated with good response to treatment.
Subject(s)
Humans , Male , Aged, 80 and over , Balanitis , Balanitis/diagnosis , Balanitis/pathology , Balanitis/therapy , Medical IllustrationABSTRACT
Inicialmente, denominada "Balanoposthite chronique circonscrite benigne a plasmocytes", a balanite plasmocitária de Zoon é uma dermatose inflamatória crônica da glande e prepúcio afetando homens não circuncisados. As diferentes opções de tratamento para esta afecção apresentam frequentemente resultados parciais. Relatos têm demonstrado sucesso terapêutico, com o uso de tacrolimo tópico. Relatamos o uso de pimecrolimus, um homólogo de tacrolimo, com boa resposta. Dois doentes do sexo masculino, com diagnóstico de Balanite de Zoon confirmado através de biópsia, foram submetidos a um tratamento diário com pimecrolimus tópico a 1 por cento, com importante melhora da doença após 6 semanas para o paciente, 1 e 8 semanas para o 2. Conclusão: O pimecrolimus em creme pode ser uma opção para o tratamento da doença.
Initially called (in French) "Balanoposthite chronique circonscrite benigne a plasmocytes", Zoon's plasma cell balanitis is a chronic inflammatory dermatosis affecting the glans and foreskin of uncircumcised men. The different treatment options for this condition often present partial results. Reports have shown therapeutic success using topical tacrolimus. We report the use of pimecrolimus, a homologue of tacrolimus, with good response. Two male patients diagnosed with Zoon's plasma cell balanitis, confirmed by biopsy, were subjected to daily treatment with topical pimecrolimus1 percent. Significant improvement was noted in patient 1 after 6 weeks and after 8 weeks in patient 2. Conclusion: Pimecrolimus cream may be an option for the treatment of this disease.
Subject(s)
Adult , Humans , Male , Middle Aged , Balanitis/drug therapy , Dermatologic Agents/therapeutic use , Tacrolimus/analogs & derivatives , Administration, Topical , Balanitis/pathology , Plasma Cells , Treatment Outcome , Tacrolimus/therapeutic useABSTRACT
A imunoterapia com o Bacilo Calmette-Guérin é amplamente usada no tratamento e profilaxia da neoplasia urotelial superficial. As complicações associadas ao tratamento são comuns. Os autores relatam um caso de inflamação granulomatosa do pênis, associada à terapia intravesical com Bacilo Calmette-Guérin, com múltiplos nódulos eritematosos indolores localizados na glande. É também efetuada uma revisão da literatura. A balanopostite granulomatosa é uma complicação rara associada à imunoterapia com Bacilo Calmette-Guérin, com uma apresentação clinicamente heterogênea que pode dificultar o diagnóstico. O seu reconhecimento clínico é essencial para o início precoce de tuberculostáticos e interrupção de Bacilo Calmette-Guérin.
Immunotherapy with Bacillus Calmette-Guérin is widely used for treatment and prophylaxis of superficial urothelial cancer. Complications associated with Bacillus Calmette-Guérin treatment are common. The authors describe a case of granulomatous inflammation of the penis associated with intravesical Bacillus Calmette-Guérin therapy, presenting with multiple erythematous and painless nodules located on the glans. A review of the literature is also performed. Granulomatous balanoposthitis is a rare complication of Bacillus Calmette-Guérin immunotherapy, with heterogeneous clinical presentation, which can make the diagnosis difficult. Its clinical recognition is essential for early start of therapy with antitubercular agents and interruption of Bacillus Calmette-Guérin.
Subject(s)
Aged , Humans , Male , Adjuvants, Immunologic/adverse effects , BCG Vaccine/adverse effects , Balanitis/chemically induced , Granuloma/chemically induced , Administration, Intravesical , Adjuvants, Immunologic/administration & dosage , Antitubercular Agents/therapeutic use , BCG Vaccine/administration & dosage , Balanitis/drug therapy , Balanitis/pathology , Granuloma/drug therapy , Granuloma/pathology , Urinary Bladder Neoplasms/drug therapyABSTRACT
Relata-se um caso de balanite de Zoon, confirmado histopatologicamente, em homem de 68 anos que vinha sendo tratado sem sucesso com diversos corticosteróides tópicos. Apresentou regressäo completa da lesäo após o uso de laser de CO2, näo tendo necessidade de realizar circuncisäo
Subject(s)
Humans , Male , Aged , Balanitis/pathology , Balanitis/surgery , Penile Diseases/therapy , Lasers/therapeutic use , Penis/injuries , Diagnosis, Differential , Erythroplasia/diagnosisABSTRACT
Se comunica el caso de un paciente de 39 años de edad con balanitis pesudoepiteliomatosa, queratósica y micácea, con placa hiperqueratósica de aspecto verrugoso a nivel del glande.
Subject(s)
Humans , Male , Adult , Balanitis/etiology , Balanitis/pathology , Penis/pathologyABSTRACT
Se presentan dos pacientes con balanitis seudo eritroplásicas con los caracteres clínico-histológicos de las balanitis seudo eritroplásica telangiectásia y variable de Mirande y de la balanitis liquenoide purpúrica y teleangiectásica, con infiltrados linfomonocitarios. Se aportan los elementos necessarios para reafirmar la anatomía de estas nuevas entidades, tratando de aclarar, el tan controvertido cuadro de las balanitis eritroplásicas
Subject(s)
Adult , Aged , Humans , Male , Balanitis/pathologyABSTRACT
Descreve-se um caso de balanite xerótica obliterante em menino de 11 anos. Discutem a etiologia da doença, bem como sua rara ocorrência na infância
Subject(s)
Child , Humans , Male , Balanitis/pathologyABSTRACT
Se presenta un caso de Balanitis Plasmocitaria de Zoon en un joven de 19 años con una evolución de dos años. Llamando la atención la edad tan temprana de aparición. Se le practicó la circunsición desapareciendo las lesiones