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2.
Egyptian Journal of Pharmaceutical Sciences. 1997; 38 (4-6): 281-289
in English | IMEMR | ID: emr-44548

ABSTRACT

New isoxazolidin-3,5-diones[3,8], pyrazolidin-3,5-diones[4a,b,9] and other related products of barbituric acid 5a, 10 and thiobarbituric acids 5b were synthesized using the malonic acid diethyl ester 2 and 7 as intermediates. The evaluation of the antimicrobial activity of these newly compounds was carried out. The results of the study were given


Subject(s)
Barbiturates/analogs & derivatives , Isoxazoles/chemical synthesis , Pyrazoles/chemical synthesis , Malonates , Anti-Bacterial Agents/biosynthesis
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