ABSTRACT
We report a case of Tinea nigra in an adolescent living in Itapema, Santa Catarina, Brazil, who presented a hyperchromic macule on the palm of the left hand, close to another erythematous macule caused by a rabbit bite. The patient received guidance on accidents and animal bites and evolved well treated with topical butenafine for the dermatomycosis. The authors also highlight the efficacy of the dermoscopic exam in diagnosing Tinea nigra with animal bite lesions and other traumas.
Subject(s)
Adolescent , Animals , Female , Humans , Rabbits , Bites and Stings/complications , Dermoscopy/methods , Tinea/diagnosis , Antifungal Agents/therapeutic use , Benzylamines/therapeutic use , Naphthalenes/therapeutic use , Skin/pathology , Treatment Outcome , Tinea/drug therapy , Tinea/etiologySubject(s)
Benzylamines/administration & dosage , Benzylamines/adverse effects , Benzylamines/analogs & derivatives , Benzylamines/pharmacokinetics , Benzylamines/therapeutic use , Male , Naphthalenes/administration & dosage , Naphthalenes/analogs & derivatives , Naphthalenes/adverse effects , Naphthalenes/pharmacokinetics , Naphthalenes/therapeutic useABSTRACT
Superficial dermatophytoses of skin are very common infections seen in clinical practice. Besides topical imidazoles, triazoles and allylamines, topical butenafine (a benzylamine derivative) is a novel agent with broad antifungal activity. One hundred and eleven patients with tinea infections were enrolled in this multicentric, randomised, single-blind non-comparative study, which involved application of butenafine (1%) cream in tinea pedis (4 weeks) and tinea cruris and tinea corporis (2 weeks) cases. The results showed that butenafine causes rapid resolution of signs and symptoms (erythema itching, burning, crusting, scaling, etc), with good patient and physician acceptability of treatment. The broader spectrum fungicidal activity and better drug retention in superficial skin layers may be responsible for this beneficial effect.