ABSTRACT
To establish whether role of amniotic membrane as biological dressing is because of blood vessel growth into it. Design: Prospective study of 22 cases of indoor burn patients. Setting; Plastic, Reconstructive Surgery and Burns Unit, Dow Medical College and Civil Hospital, Karachi. Subjects: Twenty two cases of indoor burn patients were studied. In nine cases freeze dried amniotic membrane and in thirteen cases fresh amniotic membrane was applied. Main outcome measures: Histopathological examination of biopsy specimen to see capillary budding and vascular ingrowth into membrane. Result: In none of the 22 cases studied capillary budding and any blood vessel growth into the membrane was found. The role of amniotic membrane in the management of burn wound stands the test of time and failure of documentation of vascular ingrowth into it does not alter its clinical utility