N-bromosuccinimide as an analytical reagent for the determination of some antihypertensive agents

Oxprenolol hydrochloride, captopril nadolol, indapamide and atenolol are quantified using N-bromosuccinimide. The method depends on both direct titration using methyl red indicator and indirect iodometric titration. The stoichiometry of the reaction is ascertained in each case. The methods are successfully applied for the determination of the mentioned drugs in their tablet formulation