Evaluation and comparison of anti-Candida effect of heat cure polymethylmethacrylate resin enforced with silver nanoparticles and conventional heat cure resins: An in vitro study.

Recent years have been dominated by research in nano science. Dentistry is no exception and there is increased research on nanoparticles in dentistry. Complete dentures increase the carriage of Candida in healthy patients, and the proliferation of C. albicans can be associated with denture-induced stomatitis. Purpose: To evaluate the anti-Candida effect of heat cure denture base resins reinforced with Ag° in the ratio of 4:1, 3:1, 2:1 (Groups B, C, and D, respectively) to the weight of denture base resins. Materials and Methods: Ag° were synthesized by chemical reduction method, incorporated into the polymer powder according to the ratio for each group, subjected to polymerization and microbial assay was calculated for the reference C. albicans strains by agar diffusion method for the incubation period of 24 h. Results: Group D showed multifold decrease in the colony-forming units. Conclusion: The antimicrobial effect of silver could be used vividly in the denture base for immunocompromised and geriatric patients.

Treatment of the fungal infections of the female genital tract by different modalities of treatment

This study was done to manage the fungal infections of the lower female genital tract by different methods of treatment. It was done on 160 non-pregnant women complaining from fungal infection. After full clinical examination and taking cervical and vaginal swabs for microscopic examinations and cultured on Sabouraud's dextrose agar media, all cases were divided into three groups. The first group included 20 cases received oral treatment as fluconazole and ketoconazole only; the second group included 60 cases, every 10 cases received local treatment as miconazole [vag. ovule], tioconazole [vag. ovule], clotrimazole [vag. Ovule], povidone-iodine [vag. Ovule], econazole [vag. ovule] and gentian violet [as paint] and the third group included 80 cases received systemic and local treatment. Every eight cases from these groups received fluconazole plus miconazole nitrate, fluconazole plus tioconazole, fluconazole plus clotrimazole, fluconazole plus povidone-iodine, fluconazole plus econazole, ketoconazole plus miconazole nitrate, ketoconazole plus tioconazole ketoconazole, caplus tioconazole, ketoconazole plus clotrimazole, ketoconazole plus povidone-iodine and ketoconazole plus econazole