Bilateral upper eyelid coloboma and median groove of the nose

Colobomata of the eyelid are well-recognized and are usually unilateral. Bilateral eyelid coloboma is relatively rare. A six-months old male baby had large colobomata of both upper eyelids and a deep furrow at the tip of nose. The patient had no other facial or systemic abnormalities. Although coloboma was of the same size on both sides, only the right cornea showed xerosis and opacification secondary to exposure. The symmetrical eyelid colobomata and the central furrow in the tip of nose suggest that deformity developed due to a mechanical factor, probably from pressure caused by amniotic bands. [Pakistan Journal of Ophthalmology 8: 87-97, 1992]