ABSTRACT
El porcentaje de presentacion de cancer es menor en relacion a años anteriores por lo demostrado en este estudio. El mayor porcentaje de polipos encontrados correspondieron al tipo adenomatoso y de estos el tipo tubular fue el mas frecuente. El rectosignoides es el sitio de mayor presenatacion de polipos cualquiera fuera su tipo histopatologico. La colonoscopia es el metodo diagnosticado ideal para los casos de polipos juntamente con la biopsia y la polipectomia...
Subject(s)
Male , Female , Humans , Colonoscopy , Endoscopy, Gastrointestinal , Gastroenterology , Colonic Polyps , Colonic Polyps/blood supply , Colonic Polyps/ultrastructureABSTRACT
This work was undertaken to quantify mast cells in order to investigate their role in determining the likelihood of malignant changes in colorectal polyps. The mean number of mast cells showed significant differences in various colonic disorders studied. On ultrastructure background, there was difference in mast cell character between non neolplastic and neoplastic polyps such as the degree of maturity and the intensity of chymase staining reaction. From this study we might speculate that mast cells may play a role in triggering the early phase of malignant changes in colonic polyps. Mast cells may be useful as marker of colorectal neoplasia. The mechanism of action of mast cells has not been yet elucidated
Subject(s)
Humans , Colonic Polyps/ultrastructure , Microscopy, Electron , Mast Cells , BiomarkersABSTRACT
O adenoma intestinal é uma lesäo benigna que apresenta um potencial de malignizaçäo para displasia grave e posteriormente adenocarcinoma invasivo. A remoçäo endoscópica desta lesäo constitui um tratamento curativo. Relata-se a experiência dos autores em dois casos de adenoma com displasia grave, removidos por polipectomia endoscópica