ABSTRACT
Cysticercosis-related mortality has not been studied in Brazil. Deaths recorded in the State of São Paulo from 1985 to 2004 in which cysticercosis was mentioned on any line or in any part of the death certificate were studied. Causes of death were processed using the Multiple Cause Tabulator. Over this 20-year period, cysticercosis was identified in 1,570 deaths: as the underlying cause in 1,131 and as an associated cause of death in 439. Standardized mortality rates with cysticercosis as the underlying cause showed a downward trend and were higher among men and older individuals. Intracranial hypertension, cerebral edema, hydrocephalus, inflammatory diseases of the central nervous system, and cerebrovascular diseases were the main associated causes in deaths due to cysticercosis. AIDS was the principal underlying cause of death in which cysticercosis was an associated cause. The counties (municipalities) with the most cysticercosis-related deaths were São Paulo, Campinas, Ribeirão Preto, and Santo André. Wide variation was observed between counties regarding the value ascribed to cysticercosis as the underlying cause of death. This leads to underestimation of the disease's importance in planning health interventions.
A mortalidade relacionada à cisticercose na população não tem sido pesquisada no Brasil. Foram estudados os óbitos registrados entre 1985 e 2004 no Estado de São Paulo em que a cisticercose foi mencionada em qualquer linha ou parte da Declaração de Óbito. As causas de morte foram processadas pelo Tabulador de Causas Múltiplas. No período de vinte anos ocorreram 1.570 óbitos, sendo a cisticercose causa básica em 1.131 e causa associada de morte em 439. Os coeficientes padronizados de mortalidade por cisticercose como causa básica apresentaram tendência de declínio, foram maiores entre os homens e nas idades mais avançadas. As principais causas associadas nas mortes por cisticercose foram hipertensão intracraniana, edema cerebral, hidrocefalias, doenças inflamatórias do sistema nervoso central e doenças cerebrovasculares. A AIDS foi a principal causa básica nas mortes com a cisticercose como causa associada. Os municípios com maior número de mortes foram São Paulo, Campinas, Ribeirão Preto e Santo André. Observou-se grande variação entre os municípios na valorização da cisticercose como causa básica de morte, determinando sua subestima para subsidiar o planejamento de políticas de saúde.
Subject(s)
Cysticercosis/mortality , BrazilABSTRACT
Background. Previous studies have shown an increased frequency of chromosomal abnormalities in lymphocytes from animals and humans with cysticercosis. Some reports have suggested an association between neurocysticercosis and cancer. Methods. We designed a mortality rate study from the autopsy files of the Department of pathology at the General Hospital of Mexico. A total of 1,271 autopsy files were reviewed. All files in which a malignant neoplasia was found during autopsy were selected a cases. Autopsies in which no malignant disease was found were used as controls. The odds ratio was determined between the frequency of neurocysticercosis in patients with any malignant neoplasia and that of the controls. Results. Neurocysticercosis was more frequent in cases with malignant hematological diseases (MHD), than in controls (p= 0.01). The odds ratio for this association was 3.54, with 95 percent confidence interval from 1.17-9-79. Conclusions. Most human cancers arise from the interaction of a multiplicity of factors, indluding xenobiotics and endogenous constituents. Therefore, while it will be difficult to demostrate that neurocysticercosis is a causal agent of malignant hematological diseases (MHD), it should be considered as a potential risk factor for cancer induction in countries where cysticercosis remains a public health problem
Subject(s)
Humans , Female , Adolescent , Adult , Middle Aged , Cysticercosis/complications , Cysticercosis/mortality , Lymphoma , Neoplasms/complications , Neoplasms/mortalityABSTRACT
Foi realizado estudo retrospectivo de pacientes internados no Hospital das Clínicas da Faculdade de Medicina da Universidade de Säo Paulo, Säo Paulo (Brasil), no período de 7 anos (1979 a 1985), tendo sido diagnosticados 260 casos de cisticercose, corrrespondendo a 0,2
Subject(s)
Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Humans , Male , Female , History, 20th Century , Cysticercosis , Hospitalization , Health Surveys , Brazil , Cysticercosis/diagnosis , Cysticercosis/mortality , Cysticercosis/epidemiology , Hospitals, UniversityABSTRACT
La Neurocisticercosis multiquistica racemosa basal es una afeccion maligna con alta mortalidad hasta ahora por falta de tratamiento especifico. La enfermedad ha disminuido notablemente en Bogota por las medidas sanitarias, pero aun persiste en algunas zonas del pais. La aparicion de un nuevo cestocida util contra las formas embrionarias y las tenias constituye una esperanza para los enfermos con estas parasitosis. En este articulo se presenta un caso quirurgicamente en el cual la evolucion progresiva y el deterioro clinico fue detenida con la administracion de Praziquantel, con recuperacion del paciente.