Manifestaciones cutáneas de las enfermedades sistémicas / Cutaneous manifestations of systemic diseases

La piel posee un doble origen embriológico ectomesodérmico, por lo que se relaciona con todos los órganos y sistemas del organismo. Es por esto que la piel puede reflejar alteraciones sistémicas de todo tipo, existiendo algunos marcadores dermatológicos bien reconocidos que pueden preceder, acompañar o seguir al diagnóstico de una enfermedad sistémica. La fácil accesibilidad de la piel para toma de muestra (cultivos, biopsias) facilita el estudio a cabalidad. El integrar los hallazgos clínicos con las lesiones de la piel, es una tarea difícil, que tanto dermatólogos como otros especialistas deben poner especial atención. Al estudiar el organismo humano desde el punto de vista de los diferentes sistemas se puede observar cómo en cada casoexisten lesiones cutáneas que están íntimamente ligadas a estaspatologías. En algunos casos estas lesiones son parte de la enfermedad o en otros casos son producto de la enfermedad.

The skin has a double embryological origin therefore relates to all organs and body systems. For this reason, the skin may reflect systemic changes of all kinds, with some well-recognized dermatological markers that may precede, accompany or follow the diagnosis of systemic disease. The easy accessibility of skin samples (for cultures, biopsies) facilitates research. Integrating clinical findings and skin lesions is a difficult task, for both dermatologists and other specialists, close attention is necessary. In studying the human organism from the view point of the different systems you can see how in each case there are skin lesions that are closely related to these pathologies. In some cases these lesions are part of the disease or in other cases are caused by the disease.

Role of colostrum in gastrointestinal infections.

Colostrum is breast milk produced after the birth of the newborn and lasts for 2-4 days. Colostrum is very important part of breast milk and lays down the immune system and confers growth factors and other protective factors for the young ones in mammals. This is the source of passive immunity transferred to the baby from the mother. The biological value of bovine colostrum in present day medical practice is documented in clinical trials and large databases containing case reports and anecdotal findings. The main actions include an antibacterial effect and modulation of immune response with the ability to neutralize lipopolysaccharides arising from gram negative bacterial pathogens. It has been found to be effective in infantile hemorrhagic diarrheas, other diarrheas and reduces the likelihood of disease progressing to hemolytic uremic syndrome. It has also been tested in H. pylori infection and diarrhea in immunodeficiency. Side effects of clinical relevance are limited to possible intolerance due to lactose and sensitivity to milk proteins.