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1.
Bull Indian Inst Hist Med Hyderabad ; 2005 Jan-Jun; 35(1): 21-32
Article in English | IMSEAR | ID: sea-1748

ABSTRACT

Safety and efficacy of a drug mainly depends on the method of preparation. To assess the quality of a finished product, there should be some basic standards as well as methods of preparation. There are several parameters for testing the quality of a chemical drug, which have, are true indicators. So, there is no problem in assessing a synthetic drug's quality. As far as the preparation used in Ayurvĕdic system of medicine, a drug formulation or design may not be a problem, because many formulations are well documented in classical texts. But, there is confusion with respect to standards to be followed while preparing a formulation as well as basic parameters to assess the quality of the finished product. In Ayurvĕda, pañcavidhakaşăyakalpana are the basic pharmaceutical preparations, from which all the other preparations are developed. A specific method for each and every preparation and some basic standards of finished products are mentioned in Ayurvĕdic texts to maintain their quality. This information may some times vary from text to text. To overcome this problem Sărangdhara mentioned detailed information about various formulations with respect to their methods of preparation as well as basic standards and are documented in Sărangdhara Samhita.


Subject(s)
Drug Compounding/history , Formularies as Topic/history , History, Medieval , Humans , Medicine, Ayurvedic/history , Plant Preparations/history
2.
Bull Indian Inst Hist Med Hyderabad ; 2003 Jan-Jun; 33(1): 1-16
Article in English | IMSEAR | ID: sea-2068

ABSTRACT

Man has been fascinated by nature since he evolved from his primitive ancestors, the apes. No doubt to start with, he hunted for food mainly by killing the wild animals, but if there was anything on which he could depend upon with any confidence towards its availability, it was the plant. Not only the fact that a large number of plants provided him with food but also the fact that they provided him with curative medicine and shelter, were perhaps the reasons why he worshiped them more than the animals which also gave him food. There are a large number of plants, which are used by the people all over India for curse against witchcraft or to remove the effect of the evil eye and sickness. The use of the flora in India to relieve mankind from their sufferings was known from the ancient days. This includes all food, fuel, shelter, drugs, cosmetics etc. The standards have been maintained for several centuries since the disciples were trained in the forest close to the natural flora. In the present paper certain useful methodologies are evaluated for preparing standard Herbal formulations and focus mainly on two things namely drug (Dravya) and industry (pharmaceutical industry).


Subject(s)
Drug Compounding/history , History, Ancient , India , Medicine, Ayurvedic/history , Plants, Medicinal
3.
Bull Indian Inst Hist Med Hyderabad ; 2003 Jan-Jun; 33(1): 93-112
Article in English | IMSEAR | ID: sea-1734

ABSTRACT

This Indian Institute of History of Medicine possesses more than 100 medical manuscripts (paper) in Arabic, Persian and Urdu languages. One of the rare manuscripts is known as "Moalejat-e-Hindi", its specialty is that it is on ăyurvĕda in Persian. It contains shlokas in transliterated form. It contains three sections. It has been compiled by the order of Nizam-III of Hyderabad.


Subject(s)
Drug Compounding/history , History, Ancient , India , /history , Materia Medica/history , Medicine, Ayurvedic/history
4.
São Paulo; s.n; 2001. 133 p. ilus, tab, graf.
Thesis in Portuguese | LILACS | ID: lil-313788

ABSTRACT

Neste trabalho foi feito um estudo para obtenção de formulações multiparticuladas, formadas por micropartículas de polímeros naturais, solúveis em água, não tóxicos e biodegradáveis. Os polímeros utilizados foram: Caseína, Hidroxietilcelulose (HEC), Hidroxipropilmetilcelulose (HPMC), Alginato de sódio e Quitosana. As técnicas utilizadas para obtenção das micropartículas foram o spray drying e a atomização de alginato de sódio em uma solução de CaCl2, para gelificação das gotículas formadas, com uma complexaço ou não com quitosana. O estudo de micropartículas secas de alginato de cálcio e alginato de cálcio recoberta com uma membrana de qutosana revelou que diferentes procedimentos e variáveis de processo influenciavam...


Subject(s)
Animals , Capsules/pharmacokinetics , Caseins/analysis , Caseins/pharmacokinetics , Drug Compounding/history , Drug Compounding/methods , In Vitro Techniques , Insecticides , Polymers/analysis , Polymers/pharmacokinetics , Polymers/pharmacology , Biodegradation, Environmental , Biological Assay , Calorimetry, Differential Scanning , Chemistry, Pharmaceutical , Microscopy, Electron, Scanning , Microscopy, Confocal
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