ABSTRACT
We report a 54-year-old male patient who developed an unusual form of generalized drug eruption. He had pain and breathlessness on the left chest wall. He had history of taking several drugs at private clinics under a diagnosis of herpes zoster. Two weeks later he had a generalized skin eruption. Examination showed multiple variable sized, mild pruritic, erythematous macules and papules on the face and upper extremities. Skin lesions take the form of a clinically consistent with disseminated superficial actinic porokeratosis (DSAP). Methylprednisolone 16 mg, astemisole 10 mg, oxatomide 60 mg was prescribed. Topical corticosteroid cream was applied. Within two months, his eruption had cleared almost completely. The pathogenetic mechanisms of this case are unclear, but drug and UV light have been considered.
Subject(s)
Humans , Male , Drug Eruptions/physiopathology , Drug Eruptions/etiology , Drug Eruptions/drug therapy , Facial Dermatoses/pathology , Facial Dermatoses/drug therapy , Facial Dermatoses/chemically induced , Hand Dermatoses/pathology , Hand Dermatoses/drug therapy , Hand Dermatoses/chemically induced , Herpes Zoster/complications , Middle Aged , Porokeratosis/pathology , Porokeratosis/drug therapy , Porokeratosis/chemically inducedABSTRACT
Os autores fazem uma revisão bibliográfica da fisiopatogenia, diagnóstico e principais expressões dermatológicas das erupções cutâneas provocadas por drogas, bem como seu tratamento
Subject(s)
Humans , Drug Eruptions/physiopathology , Drug Eruptions/diagnosis , Drug Eruptions/therapyABSTRACT
Se presentan dos casos de dermatitis livedoide de Nicolau, necrosis cutánea secundaria a una inyección intrarterial accidental. Las drogas involucradas en estos casos son ampicilina benzatínica y un derivado pirazolónico. Asimismo comentamos las distintas teorías patogénicas y los diferentes diagnósticos diferenciales que podrían plantearse