ABSTRACT
In recent years there has been a growing interest towards pediatric movement disorders (PMD). The data derived from the synthesis of clinical observation, neuroimaging, biochemical and, molecular genetics studies have allowed for the identification of a significant number of pediatric diseases featuring movement disorders. The purpose of this review is to outline an approach to the advances in management of dystonia, neurotransmitter disorders, tics, and paroxysmal dyskinetic syndromes starting in children younger than 18 yr of age.
Subject(s)
Age Distribution , Age of Onset , Baclofen/therapeutic use , Benzodiazepines/therapeutic use , Child , Child, Preschool , Cholinergic Antagonists/therapeutic use , Dopamine Agents/therapeutic use , Drug Therapy, Combination , Dyskinesias/diagnosis , Dyskinesias/drug therapy , Dyskinesias/epidemiology , Early Diagnosis , Electromyography , Female , Humans , Incidence , Infant , Levodopa/therapeutic use , Male , Movement Disorders/diagnosis , Movement Disorders/drug therapy , Movement Disorders/epidemiology , Physical Examination , Prognosis , Risk Assessment , Severity of Illness Index , Sex Distribution , Spain , Treatment OutcomeABSTRACT
Nous avons rapporte les resultats d'une etude de 30 cas des mouvements anormaux de l'enfant dans le service de pediatrie du CHU de Gabriel Toure de Bamako sur une periode de 11 mois.La tranche d'age la plus touchee etait de 1 a 5 ans ; les garcons etaient le plus atteint avec un sex-ratio de 1;72. Les cas de dystonie et les chorees etaient le plus representes et reconnaissaient comme etiologies les infections. Les tics etaient le moins representes. La forme generalise et permanente des mouvements anormaux etaient le plus souvent rencontree dans notre echantillon. Le traitement traditionnel avait une place importante dans la therapeutique des sujets de notre etude. Dans notre etude nous avons recu un cas qui a accuse un traitement traditionnel comme facteur declanchant les mouvements anormaux
Subject(s)
Dyskinesias/epidemiology , Dyskinesias/etiologyABSTRACT
A Discinesia Tardia (DT) representa uma séria complicação da terapia neuroléptica por seu caráter potencialmente irreversível, sua natureza iatrogênica e ausência do tratamento eficaz. Neste estudo, os autores investigam a prevalência e os fatores associados à DT por meio de inquérito clinico realizado em 310 pacientes crônicos, de ambos os sexos, internados no Centro Hospitalar Psiquiátrico de Barbacena. Os pacientes foram avaliados utilizando-se a escala AIMS (Abnormal Involuntary Movement Scale), analisando-se também outras variáveis, como sexo, idade, tempo de internação, uso de neurolépticos e diagnóstico psiquiátrico. Entre os pacientes estudados, 27,6% apresentaram sinais clínicos compatíveis com o diagnóstico de DT, sendo 54,2% do sexo feminino e 45,8% do sexo masculino. O tempo de internação, a idade e o uso de neurolépticos foram as variáveis relacionadas com a ocorrência de DT, não sendo observadas diferenças entre as demais variáveis pesquisadas.
Tardive dyskinesia (TD) is a serious complication of neuroleptic drug therapy, because of its irreversibiliry, lack of effective treatment and iatrogenic nature. In this article, the authors investigate the prevalence and associated factors of TD among 310 inpatients of Psychiatric Hospital Center of Barbacena, using the Abnormal Involuntary Movement Scale. Some variables such as sex, age, time of hospitalization, use of neuroleptics and psychiatric diagnosis were also analyzed. The prevalence of TD among the patients in the hospital was 27,6% and the distribution was: 54,2% in women and 45,8% of men. The time of hospitalization, the age and the use of neuroleptics were the only variables associated with the ocorrence of TD.
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged, 80 and over , Antipsychotic Agents/adverse effects , Dyskinesias/epidemiology , Iatrogenic Disease/epidemiology , Dyskinesias/complications , Hospitals, PsychiatricABSTRACT
Tardive Dyskinesia is a serious, long term side effect of chronic neuroleptic treatment. The magnitude of this iatrogenic health problem has been compounded by the inadequate currently available. All schizophrenic patents residing in the three main hospitals in Alexandria with Psychiatric inpatient units were studied during May and June 1988. The aim of this work was to detect Tardive Dyskinesia [TD] among schizophrenic inpatients and to study the relationship between TD and cognitive impairment. Only case fitting the DSM III diagnostic criteria for schizophrenia and who were under neuroleptic treatment for more than one year were included in this study [280 patients, 161 males and 119 females]. The study showed that TD prevalence rate among the schizophrenic population was 4.2% [lips and personal movements in 58.3% and tongue movements in [41.6%]. Patients with TD performed significantly lower than patients without TD on the comprehension, digit span and similarities subscales of Wechsler Adult Intelligence Scale [t= 3.51, 6.022 and - 3.26 respectively]. All the correlation between scores on comprehension and digit span subscales and lip movements were statistically significant [r=0.467 and 0.622]