ABSTRACT
Abstract: Ecthyma gangrenosum is a rare skin infection classically associated with Pseudomonas aeruginosa. We performed a retrospective study of all cases diagnosed with ecthyma gangrenosum from 2004-2010 in a university hospital in Mexico (8 cases, 5 female patients and 3 male patients, ages between 4 months and 2 years). The most common risk factor for ecthyma gangrenosum is neutropenia in immunocompromised patients. In previously healthy patients, immunological evaluation is important to rule out underlying immunodeficiency. Ecthyma gangrenosum in healthy patients has a high mortality rate and early diagnosis and aggressive antibiotic treatment is imperative as it can improve patients' prognosis.
Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Pseudomonas aeruginosa/isolation & purification , Pseudomonas Infections/complications , Ecthyma/microbiology , Gangrene/microbiology , Retrospective Studies , Ecthyma/drug therapy , Gangrene/drug therapyABSTRACT
Abstract Ecthyma gangrenosum is an uncommon dermatological manifestation characterized by round, indurated ulcers with a central necrotic black eschar and surrounding erythema. This report describes the case of a 5-year-old girl, affected by acute lymphocytic leukemia, presenting with a black eschar on her right thigh. Such lesions should always be correctly identified to avoid potentially fatal bacteraemia. Furthermore, because of its similar clinical presentation, cutaneous anthrax must be ruled out.
Subject(s)
Humans , Female , Child, Preschool , Pseudomonas Infections/microbiology , Skin Ulcer/microbiology , Ecthyma/microbiology , Precursor Cell Lymphoblastic Leukemia-Lymphoma/complications , Pseudomonas aeruginosa , Pseudomonas Infections/pathology , Skin Ulcer/pathology , Ecthyma/pathologyABSTRACT
El ectima gangrenoso es una vasculitis necrosante poco frecuente, en la mayoría de los casos secundaria a sepsis por Pseudomonas aeruginosa en pacientes inmunocomprometidos. Sin embargo, existen reportes de ectima gangrenoso secundarios a otras etiologías infecciosas. Presentamos un caso de ectima gangrenoso asociado a una infección por Staphylococcus aureus resistente a meticilina en una paciente sin los factores de riesgo clásicos de inmunosupresión que se describen en la literatura médica.
Ecthyma gangrenosum is an uncommon necrotizing vasculitis, in most cases secondary to sepsis by Pseudo-mona aeruginosa in immunocompromised patients. However, there have been several reports of ecthyma gangre-nosum caused by other infectious etiologies. We report an unusual case of ecthyma gangrenosum associated with methicillin-resistant Staphylococcus aureus infection in a patient without the classic immunological risk factors described in the literature.
Subject(s)
Humans , Female , Aged , Staphylococcal Infections/pathology , Ecthyma/microbiology , Ecthyma/pathology , Methicillin-Resistant Staphylococcus aureus/isolation & purification , Staphylococcal Infections/drug therapy , Biopsy , Risk Factors , Ecthyma/drug therapy , Epidermis/microbiology , Epidermis/pathology , Gangrene , ImmunocompetenceABSTRACT
Estudo clínico-epidemiológico e bacteriológico de ectima, em 2.377 crianças, revelou prevalência de 12%, com predomínio no sexo masculino em relaçäo ao feminino e nos melânicos, comparados aos leucodérmicos. Sugere influência de pequenos traumatismos cutâneos e de condiçöes socioeconômicas precárias como fatores predisponentes, e a ocorrência de tipos etiológicos específicos de estafilococos e estreptococos. É valorizada a importância do tratamento precoce
Subject(s)
Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Humans , Male , Female , Ecthyma/epidemiology , Brazil , Ecthyma/microbiology , Socioeconomic FactorsABSTRACT
Se comunica un caso de ectyma gangrenosos provocado por una cepa de P. aeruginosa resistente a la Gentamicina en un lactante con una severa alteración de la inmunidad celular. El paciente recibió tratamiento con antibióticos adecuados, inmunoglobulina normal e.v. y Levamisol. Con este tratamiento se observó esterilización de los cultivos y mejoría de las condiciones clínicas en un plazo de 2 semanas. Controles a distancia de uno y dos años del proceso mostraron total normalización de los parámetros de inmunidad celular