ABSTRACT
La embolización de cristales de colesterol genera un síndrome multiorgánico inespecífico, severo, relativamente infrecuente y de difícil diagnóstico. Se produce por la oclusión de pequeños vasos en diferentes sistemas, entre ellos la piel, órgano diana frecuente. Se comunica el caso de un varón de 69 años con múltiples factores de riesgo cardiovascular y varios eventos desencadenantes que presentó embolización por microcristales de colesterol con compromiso cutáneo y renal.
Cholesterol crystal embolization is a rare and severe multiorganic syn-drome of diffi cult diagnosis. It occurs as a result of the occlusion of smallvessels in diff erent organs, being the skin a frequent diana.We present the case of a 69 years-old male with multiple cardiovascularrisk factors and many precipitant events. He developed cholesterol em-bolization syndrome with cutaneous and renal involvement.
Subject(s)
Humans , Male , Aged , Embolism, Cholesterol/complications , Embolism, Cholesterol/diagnosis , Embolism, Cholesterol/drug therapy , Embolism, Cholesterol/therapy , Blue Toe Syndrome/diagnosis , Blue Toe Syndrome/etiology , Renal Insufficiency/etiology , Livedo Reticularis/etiologyABSTRACT
We report a 72 year-old male, that after a coronary angiogram presented pain, reduced distal skin temperature of both limbs, cyanosis of toes with preserved peripheral pulses and a rapidly progressive renal failure. Afterwards, the patient suffered a sudden bilateral amblyopia and hematochezia. Cholesterol embolism was confirmed with a skin biopsy and fundoscopy. A colonoscopy showed a possible ischemic colitis. After six months of follow up, the patient lost the distal phalanges of three toes, and renal failure stabilized, with a serum creatinine of 2.5 mg/dl. The diagnosis of cholesterol embolism is often missed, but it has a one year mortality of 80 percent and the presence of renal failure is the main prognostic indicator. Other prognostic indicators are the presence of high blood pressure, previous renal failure and peripheral artery disease.