ABSTRACT
Abstract Chikungunya, an alphavirus infection presenting with fever, rash, and polyarthritis, is most often an acute febrile illness. Neurologic complications of chikungunya infection have been reported. Here we report the clinical and neuroimaging data of 2 patients with chikungunya-associated encephalitis during the recent Brazilian epidemic.
Subject(s)
Humans , Male , Aged , Encephalitis, Viral/virology , Chikungunya Fever/complications , Brazil/epidemiology , Magnetic Resonance Imaging , Disease Outbreaks , Encephalitis, Viral/diagnostic imaging , Chikungunya Fever/epidemiology , Middle AgedABSTRACT
Abstract The symptoms of chikungunya virus (CHIKV) infection include fever, headache, muscle aches, skin rash, and polyarthralgia, characterized by intense pain, edema, and temporary functional impairment. This is the first report of encephalitis caused by CHIKV infection associated with an atypical presentation of syndrome of inappropriate antidiuretic hormone secretion, evolving to cognitive impairment and apraxia of speech.