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Rev. chil. infectol ; 28(4): 359-362, ago. 2011. ilus
Article in Spanish | LILACS | ID: lil-603067

ABSTRACT

We present the case of a 12-year-old boy with acute lymphocytic leukemia who developed pneumonia and multiple brain infarcts compatible with acute necrotic encephalitis. The infectious disease screening tests revealed influenza A H1N1 virus, Staphylococcus aureus in broncho alveolar lavage, E. coli and galactomannan antigen in blood. CNS influenza associated complications are reviewed. This case highlights the importance of magnetic resonance imaging as a diagnostic tool in the assessment of immunocompromised patients with CNS compromise and the value of brain biopsy in the final identification of an infectious disease etiology.


Escolar de 12 años de edad, con Leucemia Linfocítica Aguda en tratamiento que desarrolla una bronconeumonía bilateral, infartos cerebrales compatibles con encefalitis necrosante aguda. El estudio infectológico demostró más de una causas infecciosa que pudiera explicar su evolución destacando influenza A H1N1, Staphylococcus aureus meticilina sensible en lavado bronco alveolar, E. coli y galactomanano en sangre. Se revisa el compromiso del SNC por influenza A H1N1. Se destaca la importancia del uso de resonancia magnética nuclear al evaluar pacientes inmunocomprometidos con complicaciones neurológicas y el aporte de una biopsia cerebral en aclarar la etiología de este compromiso.


Subject(s)
Child , Humans , Male , Encephalitis, Viral/virology , Immunocompromised Host/immunology , Influenza A Virus, H1N1 Subtype/isolation & purification , Influenza, Human/virology , Precursor Cell Lymphoblastic Leukemia-Lymphoma/immunology , Bronchoalveolar Lavage Fluid/microbiology , Encephalitis, Viral/immunology , Escherichia coli Infections/diagnosis , Fatal Outcome , Influenza, Human/immunology , Magnetic Resonance Imaging , Staphylococcal Infections/diagnosis
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