Serum uric acid in primary nocturnal enuresis

A case control study was conducted on 41 cases of primary nocturnal enuresis and 20 controls in order to evaluate the implications of serum uric acid in the pathogenesis of primary nocturnal enuresis. Serum uric acid level was significantly lower in cases when compared with controls. No significant difference was detected in serum uric acid level between enuretic children with or without behavioral disturbance. Also, no difference was detected between those considered deep sleepers by their parents or not. This relatively lower level of serum uric acid in children suffering from primary nocturnal enuresis may be a possible factor in the pathogenesis of this problem