ABSTRACT
Leprosy is a contagious, chronic infectious disease caused by Mycobacterium leprae. The immune response of the host to this bacillus is variable, determining different clinical forms of the same disease. Between the Lepromatous and Tuberculoid spectra, both stable clinical forms, the Dimorfo type can be presented, with great immunological instability, determining clinical characteristics, according to the pole to which most approaches. Leproatous dimorphic leprosy is characterized by brwn and violet macules, large number of lesions and less definition at its edges, variable sizes and alteration of sensitivity. Conjugal leprosy occurs in very few cases, knowing that intimate contaqct for a long time is an important factor, but has also demonstrated the fundamental role of immunity and genetics to acquire and develop the disease. We present two cases of lepromatous dimorphic leprosy in spouses, with 20 years of cohabitation, in which the same clinical presentation was found. Ths is an infrequent fact, given the low infectivity of the pathogen and the multiple varieties that could occur.
Subject(s)
Humans , Male , Female , Middle Aged , Leprosy, Borderline/immunology , Leprosy, Lepromatous/immunology , Disease Transmission, Infectious/prevention & control , Erythema Nodosum/diagnosis , Erythema Nodosum/therapy , Leprosy, Multibacillary/therapyABSTRACT
El síndrome de Lõfgren, es una variante aguda de la sarcoidosis, que se caracteriza por fiebre, eritema nodoso, adenomegalias hiliares pulmonares y artritis. En general, tiene un curso benigno y autolimitado, que contrasta con las formas crónicas que requieren uso de corticoides y tienen tendencia a la recidiva. Se describe aquí el caso clínico de un paciente joven, de sexo masculino, con artritis pero sin eritema nodoso, lo que dificultó el planteo diagnóstico de síndrome de Lõfgren. Se realiza además una breve descripción comparativa entre la presentación clínica de la sarcoidosis crónica y el síndrome de Lõfgren...
Subject(s)
Humans , Male , Arthritis/diagnosis , Arthritis/therapy , Erythema Nodosum/diagnosis , Erythema Nodosum/therapy , Sarcoidosis/diagnosis , Sarcoidosis/etiology , Sarcoidosis/therapyABSTRACT
Os autores fazem uma revisão bibliográfica sobre eritema nodoso, incluindo suas diversas causas, manifestações clínicas, investigação e diagnósticos diferenciais. É enfatizada que eritema nodoso pode ser a manifestação cutânea de uma doença sistêmica, logo, essa situação deve ser afastada
Subject(s)
Humans , Male , Female , Adult , Erythema Nodosum/classification , Erythema Nodosum/diagnosis , Erythema Nodosum/epidemiology , Erythema Nodosum/etiology , Erythema Nodosum/physiopathology , Erythema Nodosum/pathology , Erythema Nodosum/therapy , Diagnosis, Differential , Panniculitis , Skin DiseasesABSTRACT
Eritema nodoso é uma síndrome de hipersensibilidade do grupo das paniculites, caracterizada por nódulos eritematosos dolorosos que aparecem mais freqüentemente na superfície extensora das pernas. A doença pode ser associada a vários agentes infecciosos, não-infecciosos e a drogas. Neste artigo revisamos os principais aspectos relacionados ao eritema nodoso, destacando os agentes etiológicos, achados clínicos e laboratoriais, diagnósticos diferenciais e tratamento.
Erythema nodosum is a hypersensitivity syndrome of panniculitis group, characterized by painfull erythematous nodules thar appear most commonly on the extensor surfaces of the legs. The disease may be associated with many infeccious of not infeccious agents and drugs. In the article, we rewiew the mainly aspects related to the erythema nodosum, such as clinical and laboratory findings, differential diagnosis and treatment.
Subject(s)
Humans , Male , Female , Erythema Nodosum/diagnosis , Erythema Nodosum/etiology , Erythema Nodosum/physiopathology , Erythema Nodosum/therapy , Diagnosis, DifferentialABSTRACT
Se presentan dos casos de eritema nodoso durante el primer trimestre del embarazo, uno confundido con una infección bacteriana de la piel y otro, que se presentó después de la administración de toxoide tetánico. Ambos exitosamente con Betametasona. Se revisan las posibles etiologías y se discute el tratamiento durante el embarazo